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ribonucleotide_reductase_subunit_1

Euk-Vir

Epinotia_aporema_granulovirus

ribonucleotide_reductase_subunit_1__YP_006908510__Epinotia_aporema_granulovirus__166056

Identity

Accession:
YP_006908510 ↗
Protein ID:
ribonucleotide_reductase_subunit_1
Kingdom:
euk

Quality

87.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 486-576
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 28.0 1.20e-06 62.6% 10.1%
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5nthA01 3.40.50.10590 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Zn-dependent exopeptidases 0.62 56.0 4.39e-01 100.0% 71.9%
1wpwA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.62 43.0 2.95e-01 72.5% 45.8%
3flkA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.60 45.0 3.02e-01 78.0% 65.5%
1qhhA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 43.0 3.55e-01 75.8% 41.5%
7mi0A01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.60 41.0 3.30e-01 100.0% 34.9%
2pmqA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.58 47.0 3.52e-01 89.0% 79.9%
3d0cB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.58 46.0 3.28e-01 89.0% 60.0%
1mldA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 49.0 4.25e-01 98.9% 96.6%
4xpqA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 45.0 3.19e-01 89.0% 82.6%
6oz7B00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 48.0 3.65e-01 100.0% 75.0%
3wtbC00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 48.0 3.61e-01 100.0% 71.6%
3vk5B00 3.20.20.390 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › FMN-linked oxidoreductases 0.55 44.0 3.27e-01 89.0% 74.2%
8jx6B01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 39.0 3.07e-01 76.9% 34.5%
4w7sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 46.0 3.75e-01 97.8% 71.0%
4ru1A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 44.0 3.82e-01 100.0% 56.8%
3uugA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 46.0 3.76e-01 100.0% 58.6%
4idsA02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.53 46.0 3.64e-01 98.9% 77.3%
2bo4A01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.52 39.0 3.14e-01 100.0% 38.5%
3fi9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 46.0 3.99e-01 100.0% 91.6%
5bseA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 45.0 3.70e-01 100.0% 64.2%
2yr1A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 46.0 3.33e-01 100.0% 35.8%
3jb9X01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 43.0 3.23e-01 92.3% 51.5%
3d8uB02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 44.0 3.84e-01 100.0% 61.3%
1o97C00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 44.0 3.24e-01 97.8% 70.5%
3rhfD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 3.19e-01 100.0% 83.2%
3oy2A02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.50 42.0 3.21e-01 94.5% 41.4%
5dqpB00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.50 44.0 2.89e-01 100.0% 28.0%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5062539 7542.1.2.3 a/b three-layered sandwiches › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain II › AcnX_2nd 0.64 43.0 4.23e-01 100.0% 63.0%
5041906 2002.1.1.83 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1 0.61 50.0 3.30e-01 89.0% 55.3%
4207189 5046.1.1.1 extended segments › F-type ATP synthase subunit b › F-type ATP synthase subunit b › F-type ATP synthase subunit b › ATP-synt_B 0.61 43.0 3.24e-01 72.5% 41.3%
3656282 7588.1.1.0 a/b three-layered sandwiches › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase 0.61 43.0 4.70e-01 95.6% 95.7%
4519243 2004.1.1.49 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase 0.60 43.0 3.08e-01 76.9% 24.6%
4981993 3979.1.1.0 a+b four layers › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain 0.60 39.0 4.50e-01 96.7% 100.0%
5005213 2002.1.1.56 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Dus 0.59 49.0 3.37e-01 90.1% 66.3%
None 0.59 49.0 3.27e-01 90.1% 59.7%
5005259 2004.1.1.49 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase 0.58 48.0 2.91e-01 91.2% 82.2%
3171402 2002.1.1.56 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Dus 0.58 48.0 3.13e-01 90.1% 54.2%
3473465 2002.1.1.56 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Dus 0.58 48.0 3.17e-01 92.3% 50.7%
None 0.58 48.0 3.27e-01 92.3% 60.0%
3202878 2002.1.1.56 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Dus 0.58 47.0 2.99e-01 90.1% 53.2%
4973360 2002.1.1.36 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Pterin_bind 0.56 46.0 3.27e-01 89.0% 70.2%
3722663 7514.1.1.0 a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain 0.56 48.0 4.44e-01 98.9% 93.3%
3869472 2006.1.6.13 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_3 0.55 49.0 3.99e-01 100.0% 76.0%
4991266 2002.1.1.75 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › QRPTase_C 0.55 45.0 3.75e-01 90.1% 78.2%
4963785 7514.1.1.0 a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain 0.55 44.0 4.15e-01 100.0% 70.2%
3361648 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.55 44.0 3.42e-01 100.0% 38.1%
5019938 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 40.0 3.01e-01 76.9% 68.7%
5034779 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.55 48.0 3.85e-01 100.0% 73.2%
3819461 2002.1.1.56 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Dus 0.54 48.0 3.27e-01 100.0% 28.1%
3623775 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.54 47.0 3.39e-01 100.0% 70.0%
3612075 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 48.0 3.69e-01 100.0% 80.0%
5071731 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.54 40.0 3.51e-01 100.0% 52.1%
3894731 2007.1.2.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.53 40.0 2.87e-01 97.8% 26.1%
4015669 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.53 47.0 3.09e-01 100.0% 24.0%
5000445 2006.1.3.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.52 46.0 3.84e-01 100.0% 81.2%
5013905 2002.1.1.105 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PEP-utilizers_C 0.52 46.0 3.18e-01 100.0% 44.6%
3515603 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 43.0 3.47e-01 95.6% 64.5%
5083400 2002.1.1.105 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › PEP-utilizers_C 0.52 45.0 3.36e-01 94.5% 88.6%
3485308 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.51 45.0 3.62e-01 100.0% 74.7%
3653395 2006.1.6.9 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Copine 0.51 45.0 3.81e-01 100.0% 66.5%
3389310 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.50 40.0 3.41e-01 89.0% 79.4%
4930920 4093.1.1.1 a+b three layers › CofE-like › CofE-like › CofE-like › F420_ligase 0.50 42.0 3.61e-01 100.0% 57.9%
D2 medium residues 1-56
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3lcvB01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.71 48.0 4.78e-01 100.0% 68.4%
6ui4A02 1.20.58.530 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 47.0 3.37e-01 92.9% 25.2%
2ii2A03 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.58 42.0 3.56e-01 87.5% 43.9%
1bqbA02 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.58 46.0 3.57e-01 94.6% 59.7%
4ga4A02 3.40.1030.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 › Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 0.55 45.0 3.01e-01 98.2% 27.2%
7y4rB01 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.55 39.0 3.21e-01 75.0% 41.5%
8e9gE01 1.10.10.1590 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E 0.53 36.0 3.58e-01 78.6% 65.1%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 43.0 3.30e-01 94.6% 39.3%
3mvuA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.51 43.0 2.97e-01 100.0% 86.6%
3h5qA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.51 33.0 3.06e-01 76.8% 52.9%
4muoA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.50 32.0 3.01e-01 92.9% 50.0%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4573827 1074.1.1.1 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_lgN 0.86 78.0 6.05e-01 100.0% 52.2%
3659168 148.1.3.205 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_At3g28540 0.80 53.0 4.33e-01 100.0% 40.0%
3201189 10.12.1.21 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › ERG2_Sigma1R 0.76 49.0 3.23e-01 100.0% 17.2%
4941424 2004.1.1.76 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.69 53.0 3.16e-01 82.1% 78.1%
3652954 108.1.1.73 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5+EF-hand_7 0.66 46.0 4.28e-01 76.8% 81.3%
4947492 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.65 51.0 3.88e-01 83.9% 79.2%
3250805 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.65 49.0 4.46e-01 83.9% 87.5%
3477380 103.4.1.3 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Med15_N 0.64 44.0 4.51e-01 100.0% 74.5%
3486982 632.3.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain 0.64 44.0 4.49e-01 100.0% 74.5%
3927392 198.1.1.1 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 0.64 46.0 4.10e-01 76.8% 77.5%
3714062 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 42.0 2.43e-01 75.0% 20.3%
3618873 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.55 34.0 3.39e-01 100.0% 58.3%
3992404 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.55 34.0 3.05e-01 100.0% 41.2%
3320919 2003.1.5.14 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3 0.54 43.0 3.00e-01 100.0% 97.9%
4330938 4041.1.1.1 a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.53 42.0 3.03e-01 96.4% 61.0%
3396075 198.1.1.2 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 0.53 38.0 3.42e-01 78.6% 66.3%
4499385 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.50 37.0 2.68e-01 78.6% 68.8%
3288392 608.1.1.1 alpha arrays › AhpD-like › AhpD-like › AhpD-like › CMD 0.50 37.0 3.01e-01 82.1% 82.6%
D3 medium residues 57-72_298-485
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 43.8 2.00e-11 98.0% 18.1%
D4 medium residues 73-181_256-297
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 26.7 3.00e-06 31.1% 7.2%
D5 medium residues 182-255
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 32.9 4.00e-08 100.0% 13.0%