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ribonucleotide_reductase_subunit_1

Euk-Vir

Equid_alphaherpesvirus_3

ribonucleotide_reductase_subunit_1__YP_009054924__Equid_alphaherpesvirus_3__80341

Identity

Accession:
YP_009054924 ↗
Protein ID:
ribonucleotide_reductase_subunit_1
Kingdom:
euk

Quality

91.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Equid_alphaherpesvirus_3

TaxID: 80341

Cluster

View cluster (122 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 222-389
PDB
Domain cluster: rep: IMGVR_UViG_3300028089_000252-3300028089-Ga0255299_10029802__D277-388_452-478
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 116.5 1.80e-33 99.4% 29.8%
D2 medium residues 6-85
PDB
Domain cluster: rep: ribonucleotide_reductase_subunit_1__YP_009137191__Human_alphaherpesvirus_2__10310__D371-445
D3 medium residues 86-155_177-203
PDB
Domain cluster: rep: ribonucleotide_reductase_subunit_1__NP_077434__Cercopithecine_alphaherpesvirus_9__35246__D89-165
D4 medium residues 156-176_204-219_451-613
PDB
Domain cluster: rep: rr1__YP_009552690__Operophtera_brumata_nucleopolyhedrovirus__1046267__D445-618_684-706
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 124.3 8.40e-36 91.5% 29.6%
D5 medium residues 390-414_614-645_701-778
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 65.6 5.10e-18 47.4% 11.3%
PF02867.21 Ribonuc_red_lgC 25.0 1.00e-05 26.7% 6.3%
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2wghA00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.89 80.0 4.89e-01 91.9% 52.2%
3r7wA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 46.0 4.17e-01 77.8% 95.1%
2hsjD00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.61 43.0 3.77e-01 74.1% 82.7%
2jaxA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.59 36.0 3.73e-01 75.6% 64.0%
5dqpB00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.58 44.0 3.14e-01 79.3% 75.7%
2z3vA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 36.0 3.65e-01 74.1% 62.0%
3v3tA01 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.57 43.0 3.74e-01 77.8% 83.4%
3oy2A02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.57 37.0 3.13e-01 76.3% 38.4%
1z8hA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.57 44.0 3.85e-01 81.5% 76.2%
5iz4A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 44.0 3.62e-01 81.5% 97.2%
4nimA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 43.0 3.61e-01 80.7% 91.3%
3s83A00 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.57 43.0 3.49e-01 79.3% 57.0%
6hcdD00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.57 36.0 3.68e-01 77.8% 63.7%
3gemD00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 43.0 3.76e-01 81.5% 97.7%
1jcjA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 47.0 3.83e-01 93.3% 95.2%
4f3hA00 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.55 41.0 3.36e-01 78.5% 58.7%
1j93A00 3.20.20.210 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 0.54 44.0 3.28e-01 85.9% 75.5%
2gs3A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.54 37.0 3.50e-01 94.1% 55.6%
1jqxA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 44.0 3.48e-01 85.9% 75.7%
3tnjA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 33.0 3.45e-01 79.3% 66.1%
4wnyA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 37.0 3.79e-01 79.3% 72.0%
2ejaA00 3.20.20.210 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 0.53 42.0 3.18e-01 84.4% 80.1%
3cynB00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.53 37.0 3.44e-01 94.1% 55.5%
2oq2D00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 39.0 3.23e-01 77.0% 56.9%
3hlkB02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 38.0 3.06e-01 74.1% 87.3%
3lm3A01 3.20.20.510 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Uncharacterised protein PF12979, DUF3863 0.52 42.0 3.30e-01 87.4% 84.6%
3weeB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.52 37.0 3.43e-01 72.6% 79.5%
6llwB01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.52 36.0 2.93e-01 80.0% 38.6%
3oo2A02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.51 42.0 3.68e-01 88.9% 89.5%
1um8A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 38.0 3.31e-01 81.5% 98.3%
3t1iA02 3.30.110.110 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Mre11, capping domain 0.50 35.0 4.00e-01 72.6% 100.0%
5w4zA00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.50 44.0 3.07e-01 95.6% 89.2%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4015532 2500.1.1.0 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.91 86.0 5.36e-01 97.0% 63.7%
3823652 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.91 85.0 5.37e-01 97.0% 68.0%
996122 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.90 85.0 5.32e-01 97.0% 63.7%
3647789 2003.1.5.31 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS 0.64 41.0 3.17e-01 78.5% 28.9%
4529833 2495.1.1.2 ↗ a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.62 36.0 4.31e-01 74.1% 85.6%
3707620 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.58 40.0 3.60e-01 88.9% 50.5%
153585 2002.5.1.1 ↗ a/b barrels › TIM beta/alpha-barrel › EAL domain › EAL domain › EAL 0.57 44.0 3.50e-01 79.3% 56.7%
4635446 2005.1.1.11 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.56 38.0 3.19e-01 81.5% 40.0%
4988934 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.56 42.0 3.17e-01 78.5% 84.2%
3180815 2002.1.1.38 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TAL_FSA 0.55 41.0 3.04e-01 77.8% 42.2%
3977088 2002.5.1.1 ↗ a/b barrels › TIM beta/alpha-barrel › EAL domain › EAL domain › EAL 0.55 41.0 3.39e-01 78.5% 57.4%
3600351 7522.1.1.0 ↗ a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.55 42.0 4.15e-01 80.7% 86.9%
3960786 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.55 42.0 3.84e-01 81.5% 94.4%
3993940 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.53 41.0 3.51e-01 81.5% 76.7%
4057588 2002.1.1.53 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Ala_racemase_N 0.53 44.0 3.64e-01 89.6% 85.0%
3953223 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.52 35.0 3.98e-01 81.5% 91.0%
3242179 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.52 41.0 3.67e-01 81.5% 88.6%
4003239 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.52 40.0 3.49e-01 80.7% 89.3%
3625748 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.52 40.0 3.53e-01 81.5% 82.5%
3999802 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.52 40.0 3.59e-01 81.5% 89.5%
4993064 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.52 39.0 3.62e-01 80.0% 65.1%
5013830 2004.1.1.66 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase_2 0.51 38.0 3.30e-01 76.3% 73.7%
4972770 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.51 37.0 3.30e-01 74.8% 58.5%
5064420 2004.1.1.146 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATPase 0.51 40.0 3.45e-01 84.4% 63.6%
4969850 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 41.0 3.14e-01 88.9% 86.5%
3735949 2005.1.1.12 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1e 0.51 44.0 3.33e-01 97.8% 99.2%
D6 medium residues 646-700
PDB
Domain cluster: rep: ribonucleotide_reductase_subunit_1__YP_182368__Gallid_alphaherpesvirus_1__10386__D639-699