←Back to structures
ribonucleotide_reductase_subunit_1
Euk-VirHuman_alphaherpesvirus_1
ribonucleotide_reductase_subunit_1__YP_009137114__Human_alphaherpesvirus_1__10298
Identity
- Accession:
- YP_009137114 ↗
- Protein ID:
- ribonucleotide_reductase_subunit_1
- Kingdom:
- euk
Quality
73.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Human_alphaherpesvirus_1
TaxID: 10298
Cluster
View cluster (122 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 582-777
Domain cluster:
rep: IMGVR_UViG_3300042092_000730-3300042092-Ga0453238_010587_859_2079__D220-402
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02867.21 best | Ribonuc_red_lgC | 141.4 | 5.50e-41 | 100.0% | 37.2% |
D2
medium
residues 319-398
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 57.0 | 5.01e-01 | 100.0% | 91.1% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 46.0 | 3.39e-01 | 78.8% | 69.2% |
| 3ckdA02 | 1.20.58.360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines | 0.60 | 44.0 | 3.85e-01 | 77.5% | 55.6% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 46.0 | 4.15e-01 | 81.2% | 86.1% |
| 7d3uC01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 46.0 | 4.17e-01 | 83.7% | 84.1% |
| 2cufA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.55 | 37.0 | 3.86e-01 | 97.5% | 77.8% |
| 4bmhA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.51 | 42.0 | 3.29e-01 | 97.5% | 61.9% |
| 1wdhA02 | 1.10.720.60 | Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › | 0.50 | 37.0 | 3.43e-01 | 77.5% | 85.3% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3625044 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.71 | 49.0 | 4.44e-01 | 71.2% | 64.8% |
| 3615526 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.69 | 45.0 | 4.58e-01 | 70.0% | 67.5% |
| 3543934 | 109.4.1.1758 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Dopey_N, TPR_DOP1_M | 0.65 | 48.0 | 3.13e-01 | 78.8% | 33.3% |
| 3858699 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.62 | 39.0 | 3.68e-01 | 83.7% | 51.0% |
| 3858695 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.59 | 45.0 | 4.45e-01 | 82.5% | 90.6% |
| 3182634 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.59 | 40.0 | 3.95e-01 | 71.2% | 67.8% |
| 3764064 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.59 | 45.0 | 4.46e-01 | 82.5% | 87.1% |
| 3934240 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.58 | 39.0 | 3.73e-01 | 97.5% | 58.9% |
| 3586162 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.56 | 47.0 | 4.20e-01 | 100.0% | 96.0% |
| 3896924 | 320.4.1.5 ↗ | a+b two layers › R3H domain-like › PUB domain › PUB domain › Gasdermin_C | 0.55 | 41.0 | 3.11e-01 | 80.0% | 94.6% |
| 3287687 | 633.23.1.7 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › DUF5336 | 0.55 | 43.0 | 3.73e-01 | 85.0% | 61.6% |
| 3231568 | 7515.1.1.19 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Sulfatase, Phosphodiest | 0.53 | 41.0 | 2.75e-01 | 85.0% | 32.2% |
| 3657422 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.51 | 39.0 | 3.81e-01 | 82.5% | 95.6% |
| 3800968 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.51 | 39.0 | 3.64e-01 | 100.0% | 65.7% |
| 3599434 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 40.0 | 2.38e-01 | 91.3% | 20.8% |
| 4406284 | 152.1.2.1 ↗ | alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 | 0.50 | 34.0 | 3.59e-01 | 71.2% | 78.6% |
D3
medium
residues 399-459_489-500
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 49.0 | 4.30e-01 | 93.2% | 89.4% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.56 | 48.0 | 4.06e-01 | 100.0% | 77.1% |
| 3dcfA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 38.0 | 3.11e-01 | 74.0% | 52.8% |
| 3ly7A02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 40.0 | 3.14e-01 | 90.4% | 35.4% |
| 3i5pA01 | 1.25.40.450 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, N-terminal subdomain | 0.54 | 48.0 | 3.98e-01 | 100.0% | 65.6% |
| 3tacB01 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.54 | 41.0 | 3.48e-01 | 83.6% | 78.7% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.51 | 44.0 | 3.90e-01 | 98.6% | 83.6% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 46.0 | 3.54e-01 | 100.0% | 51.9% |
| 1x3kA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 41.0 | 3.25e-01 | 89.0% | 59.9% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3717365 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 51.0 | 3.47e-01 | 82.2% | 73.2% |
| 4952441 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.65 | 46.0 | 3.10e-01 | 89.0% | 20.8% |
| 4512905 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.65 | 47.0 | 3.07e-01 | 82.2% | 18.1% |
| 3220791 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.61 | 54.0 | 4.00e-01 | 98.6% | 92.1% |
| 3740779 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.59 | 45.0 | 4.49e-01 | 97.3% | 80.0% |
| 3679873 | 109.4.1.90 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TOM20_plant | 0.54 | 49.0 | 3.78e-01 | 100.0% | 50.9% |
| 3412629 | 109.4.1.839 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT | 0.54 | 42.0 | 2.99e-01 | 95.9% | 26.8% |