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ribonucleotide_reductase_subunit_1

Euk-Vir

Beluga_whale_alphaherpesvirus_1

ribonucleotide_reductase_subunit_1__YP_010084951__Beluga_whale_alphaherpesvirus_1__1434720

Identity

Accession:
YP_010084951 ↗
Protein ID:
ribonucleotide_reductase_subunit_1
Kingdom:
euk

Quality

91.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Beluga_whale_alphaherpesvirus_1

TaxID: 1434720

Cluster

View cluster (122 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-94
PDB
Domain cluster: rep: ribonucleotide_reductase_subunit_1__YP_009137191__Human_alphaherpesvirus_2__10310__D371-445
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.77 62.0 5.82e-01 85.1% 94.7%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.76 62.0 5.71e-01 87.2% 90.8%
7csoA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.73 57.0 4.34e-01 84.0% 72.7%
1ki1B01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.70 56.0 4.38e-01 86.2% 80.4%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 38.0 4.55e-01 91.5% 82.3%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 53.0 4.52e-01 83.0% 79.5%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.68 55.0 4.63e-01 87.2% 73.4%
2yqdA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.68 54.0 5.05e-01 87.2% 95.8%
6d5xA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.67 55.0 4.62e-01 86.2% 80.1%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.67 40.0 4.26e-01 93.6% 67.1%
2radA03 1.20.1440.30 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain 0.67 53.0 4.82e-01 86.2% 81.9%
2ikbC00 1.20.141.10 Mainly Alpha › Up-down Bundle › Chitosanase, subunit A; domain 1 › Chitosanase, subunit A, domain 1 0.66 49.0 4.14e-01 78.7% 56.5%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.66 44.0 4.99e-01 72.3% 90.1%
1wvtA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.66 54.0 4.57e-01 87.2% 79.1%
4qgpB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.65 40.0 3.84e-01 85.1% 55.1%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.64 53.0 4.40e-01 88.3% 81.2%
4dkcB00 1.20.1250.80 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-34 0.64 48.0 4.09e-01 80.9% 62.5%
4nwpD00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.64 56.0 4.73e-01 93.6% 84.6%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 40.0 4.36e-01 93.6% 76.9%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.63 50.0 4.67e-01 85.1% 97.4%
2xheA03 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.63 45.0 4.11e-01 85.1% 57.9%
1lqsL01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 48.0 4.70e-01 81.9% 92.0%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 42.0 3.39e-01 71.3% 84.1%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.61 36.0 3.86e-01 98.9% 69.2%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 40.0 4.42e-01 96.8% 88.7%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.60 45.0 3.85e-01 79.8% 74.7%
3t9oB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.59 40.0 3.74e-01 70.2% 75.0%
3gzkA02 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.58 44.0 2.81e-01 79.8% 34.7%
1ocsA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.56 45.0 4.04e-01 87.2% 90.9%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.56 39.0 3.60e-01 100.0% 55.3%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.53 45.0 4.11e-01 94.7% 92.1%
1zbtA01 6.10.140.1950 Special › Helix non-globular › Helix Hairpins › 0.53 39.0 4.20e-01 94.7% 88.0%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.53 45.0 3.83e-01 94.7% 74.7%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.53 39.0 3.57e-01 79.8% 92.2%
3p0uA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.52 43.0 3.31e-01 91.5% 56.3%
4ehsA00 1.10.860.10 Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A 0.51 43.0 3.92e-01 91.5% 95.2%
3ckyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.51 37.0 3.34e-01 77.7% 82.1%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5039441 633.21.1.47 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › SPW 0.77 59.0 5.62e-01 80.9% 97.3%
3969893 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.75 43.0 5.17e-01 91.5% 84.6%
3705589 650.1.1.1 ↗ alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.73 45.0 4.44e-01 76.6% 58.0%
2512963 633.21.1.1 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 0.72 60.0 5.36e-01 90.4% 87.9%
3180887 174.1.1.9 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF1746 0.71 57.0 5.11e-01 86.2% 77.7%
3950032 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.71 58.0 4.34e-01 86.2% 63.3%
3606082 650.1.1.1 ↗ alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.69 44.0 4.58e-01 77.7% 67.8%
3890423 3758.1.1.0 ↗ alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.68 52.0 3.73e-01 81.9% 77.1%
3214642 2484.1.1.50 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Dimer_Tnp_hAT 0.66 56.0 3.61e-01 91.5% 50.2%
3735917 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.65 52.0 3.33e-01 85.1% 25.7%
3967544 5069.1.1.44 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › CopD 0.64 44.0 3.87e-01 70.2% 79.3%
3470828 601.1.2.4 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.64 54.0 4.88e-01 93.6% 93.1%
3593945 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 49.0 3.76e-01 80.9% 86.3%
4961908 101.1.6.0 ↗ alpha arrays › HTH › HTH › TrpR 0.62 32.0 3.47e-01 85.1% 57.5%
4438700 622.1.1.0 ↗ alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.61 44.0 4.69e-01 76.6% 85.9%
4958742 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 44.0 4.02e-01 77.7% 92.8%
3505829 101.1.2.507 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_TANC1 0.59 40.0 3.44e-01 70.2% 75.3%
3595071 650.1.1.0 ↗ alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain 0.58 44.0 4.42e-01 79.8% 83.2%
3691994 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.57 51.0 3.49e-01 96.8% 44.8%
3713097 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 49.0 3.30e-01 92.6% 39.8%
4669161 3812.1.1.16 ↗ alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › Med12 0.55 41.0 3.56e-01 77.7% 96.4%
3474944 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 42.0 3.03e-01 80.9% 52.6%
3250524 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.55 43.0 3.37e-01 85.1% 86.3%
3393225 101.1.1.66 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_5 0.54 35.0 3.64e-01 89.4% 71.8%
3400200 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 41.0 3.83e-01 83.0% 97.6%
3463858 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 39.0 3.83e-01 95.7% 71.0%
3279558 192.31.1.5 ↗ alpha bundles › Long alpha-hairpin › CP12 › CP12 › DUF4254 0.54 40.0 3.82e-01 98.9% 67.3%
3813741 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.53 45.0 4.07e-01 97.9% 84.3%
3215014 632.22.1.184 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › SMC_N 0.53 40.0 2.56e-01 92.6% 15.0%
4013204 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.53 47.0 2.94e-01 98.9% 63.3%
3839264 180.1.1.0 ↗ alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase 0.52 45.0 3.57e-01 95.7% 80.0%
3593555 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 45.0 3.57e-01 95.7% 80.0%
3270478 6155.1.1.4 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC 0.52 40.0 3.85e-01 80.9% 77.1%
3970129 7579.1.1.0 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.51 34.0 2.46e-01 72.3% 22.5%
D2 medium residues 332-429_630-641_709-783
PDB
Domain cluster: rep: ribonucleotide_reductase_subunit_1__NP_042658__Equid_gammaherpesvirus_2__12657__D311-417_701-750
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 72.2 5.10e-20 54.0% 17.8%
PF02867.21 Ribonuc_red_lgC 46.0 4.30e-12 33.0% 9.5%
D3 medium residues 501-618
PDB
Domain cluster: rep: Rr1__YP_002854736__Euproctis_pseudoconspersa_nucleopolyhedrovirus__307467__D484-597
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 96.5 2.20e-27 99.2% 21.6%