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ribonucleotide_reductase_subunit_1

Euk-Vir

Cervid_alphaherpesvirus_3

ribonucleotide_reductase_subunit_1__YP_010087566__Cervid_alphaherpesvirus_3__2115790

Identity

Accession:: YP_010087566 ↗
Protein ID:: ribonucleotide_reductase_subunit_1
Kingdom:: euk

Quality

89.5 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Cervid_alphaherpesvirus_3

TaxID: 2115790

Cluster

View cluster (122 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 19-160

PDB

Domain cluster: rep: ribonucleotide_reductase_subunit_1__NP_040142__Human_alphaherpesvirus_3__10335__D1-140

D2 high residues 456-609

PDB

Domain cluster: rep: rr1__YP_009552690__Operophtera_brumata_nucleopolyhedrovirus__1046267__D445-618_684-706

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02867.21 best	Ribonuc_red_lgC	111.5	6.30e-32	100.0%	28.4%

D3 medium residues 161-215

PDB

Domain cluster: representative

CATH (30)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1e7lA02	1.10.720.10	Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 ›	0.73	52.0	5.28e-01	76.4%	96.4%
1irzA00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.66	41.0	3.94e-01	74.5%	54.7%
3spcA02	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.65	55.0	4.32e-01	100.0%	67.7%
2ft0A00	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.64	56.0	3.71e-01	100.0%	27.5%
1u84A00	1.10.340.20	Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Apc36109-like domain	0.64	43.0	3.85e-01	81.8%	48.1%
3ufeA02	1.20.58.1950	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.63	45.0	4.59e-01	81.8%	77.4%
3oxfA05	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.62	39.0	3.55e-01	76.4%	48.0%
3b5iA02	1.10.1200.220	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ›	0.61	49.0	4.20e-01	96.4%	53.7%
4kjmA02	1.20.5.420	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C	0.61	45.0	4.57e-01	92.7%	80.0%
2gfhA02	1.20.120.710	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain	0.61	41.0	3.65e-01	87.3%	45.3%
3g0tA02	6.10.120.10	Special › Helix non-globular › 434 Repressor (Amino-terminal Domain) › Bacterial aspartate aminotransferase, helical domain	0.61	49.0	4.54e-01	89.1%	97.1%
3lulA01	3.30.470.10	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain	0.60	50.0	4.01e-01	94.5%	72.3%
1td6A03	1.10.472.40	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3	0.59	46.0	3.97e-01	98.2%	53.3%
1gcvB00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.58	48.0	3.68e-01	94.5%	82.4%
1wdhA02	1.10.720.60	Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 ›	0.57	46.0	3.91e-01	94.5%	87.3%
3cr3A00	1.25.40.340	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain	0.57	47.0	3.39e-01	100.0%	97.9%
1fadA00	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.56	46.0	4.01e-01	100.0%	89.5%
4n4gA01	1.20.920.10	Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like	0.56	49.0	3.95e-01	100.0%	94.6%
1un8A02	1.25.40.340	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain	0.56	48.0	3.37e-01	100.0%	97.9%
3ermB00	1.10.10.710	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like	0.56	42.0	4.08e-01	89.1%	73.4%
1a22A00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.55	40.0	2.96e-01	83.6%	49.4%
4griA04	1.10.8.70	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutamate-tRNA synthetase, class I, anticodon-binding domain 1	0.55	40.0	4.05e-01	89.1%	84.9%
6lcuA02	1.10.10.470	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Maltooligosyl trehalose synthase; domain 4	0.55	41.0	3.53e-01	90.9%	52.4%
4qxbB00	6.10.280.250	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	40.0	3.84e-01	83.6%	92.6%
3zgyA02	1.10.1040.10	Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	0.53	45.0	3.49e-01	98.2%	67.4%
3pivA00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.53	40.0	3.00e-01	85.5%	66.0%
2d2sA02	1.20.58.1220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain	0.53	38.0	3.20e-01	80.0%	59.4%
6m9sB01	1.20.910.10	Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like	0.52	39.0	2.68e-01	83.6%	74.7%
1hwyA01	1.10.287.140	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.52	41.0	4.25e-01	85.5%	98.0%
3shgA00	1.10.3290.10	Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain	0.51	42.0	3.00e-01	98.2%	52.5%

ECOD (29)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4308397	1074.1.1.4 ↗	alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_2_N	0.80	67.0	4.68e-01	100.0%	30.3%
5030207	1074.1.1.4 ↗	alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_2_N	0.80	67.0	5.11e-01	100.0%	41.7%
5062184	101.1.2.141 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_24	0.79	48.0	4.73e-01	80.0%	56.7%
5055914	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.74	46.0	4.66e-01	81.8%	63.6%
5062183	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.73	45.0	4.05e-01	80.0%	45.3%
5055912	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	45.0	4.15e-01	80.0%	48.6%
4948833	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	46.0	4.80e-01	80.0%	72.0%
5047333	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.72	46.0	3.92e-01	85.5%	40.0%
4945903	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	48.0	4.83e-01	81.8%	70.9%
5046275	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.70	43.0	4.34e-01	74.5%	61.8%
5058606	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.69	45.0	4.07e-01	78.2%	49.3%
185221	3502.1.1.1 ↗	alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG	0.69	49.0	4.71e-01	90.9%	64.2%
3245021	110.1.1.0 ↗	alpha arrays › DEATH domain › DEATH domain › DEATH domain	0.67	57.0	4.85e-01	94.5%	90.0%
3491310	3826.1.1.67 ↗	alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Med10	0.66	41.0	3.75e-01	74.5%	46.7%
4947069	304.123.1.0 ↗	a+b two layers › Alpha-beta plaits › PF0523-like › PF0523-like	0.66	55.0	3.75e-01	92.7%	70.8%
4489833	6130.1.1.1 ↗	alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Se-cys_synth_N	0.63	48.0	4.48e-01	83.6%	67.1%
4610257	6130.1.1.0 ↗	alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain	0.63	48.0	4.61e-01	85.5%	72.3%
5044477	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.59	47.0	3.90e-01	89.1%	60.0%
3483338	110.1.1.0 ↗	alpha arrays › DEATH domain › DEATH domain › DEATH domain	0.59	47.0	4.00e-01	96.4%	90.5%
4196397	106.1.1.1 ↗	alpha arrays › Globin-like › Globin-like › Globin-like › Globin	0.57	45.0	3.55e-01	98.2%	80.0%
4295116	6130.1.1.1 ↗	alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Se-cys_synth_N	0.56	43.0	4.01e-01	89.1%	68.0%
3481034	4009.1.1.0 ↗	alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins	0.56	47.0	4.23e-01	100.0%	72.5%
3578169	11.1.1.6 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › A2M	0.55	36.0	2.57e-01	74.5%	22.4%
3690980	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.55	45.0	3.77e-01	96.4%	56.2%
3017495	1128.1.1.2 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2	0.54	44.0	3.62e-01	96.4%	51.3%
3478409	592.1.1.5 ↗	alpha arrays › PWI domain-like › PWI domain › PWI domain › PF26084	0.52	41.0	3.65e-01	98.2%	89.5%
3603105	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.52	39.0	3.63e-01	85.5%	100.0%
4563833	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.50	41.0	2.57e-01	96.4%	37.5%
3740294	3826.1.1.0 ↗	alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR)	0.50	37.0	2.91e-01	89.1%	32.7%

D4 medium residues 216-339_413-455

PDB

Domain cluster: rep: IMGVR_UViG_3300028089_000252-3300028089-Ga0255299_10029802__D277-388_452-478

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02867.21 best	Ribonuc_red_lgC	80.6	1.40e-22	69.5%	22.5%
PF02867.21	Ribonuc_red_lgC	35.9	5.00e-09	25.8%	7.8%

D5 medium residues 340-412_739-761

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02867.21 best	Ribonuc_red_lgC	31.3	1.20e-07	81.2%	13.2%

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2wghA00	3.20.70.20	Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain ›	0.87	84.0	4.90e-01	100.0%	58.7%
2v6eA03	1.10.443.30	Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Telomere resolvase	0.52	41.0	3.18e-01	85.4%	88.4%
2bl0C01	1.10.238.10	Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand	0.52	27.0	2.97e-01	87.5%	58.7%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4822330	2500.1.1.2 ↗	a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC	0.89	86.0	5.27e-01	100.0%	86.5%
4015532	2500.1.1.0 ↗	a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel	0.88	85.0	5.02e-01	100.0%	69.7%
3823652	2500.1.1.2 ↗	a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC	0.88	85.0	5.02e-01	100.0%	74.2%
996122	2500.1.1.2 ↗	a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC	0.86	83.0	4.90e-01	100.0%	69.4%
3976699	3355.1.1.21 ↗	alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_sulph_symp, CitMHS	0.56	41.0	2.68e-01	79.2%	85.2%
3644493	219.1.1.0 ↗	a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases	0.55	39.0	2.56e-01	72.9%	86.6%

D6 medium residues 642-708

PDB

Domain cluster: rep: ribonucleotide_reductase_subunit_1__YP_182368__Gallid_alphaherpesvirus_1__10386__D639-699