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ribonucleotide_reductase_subunit_2
Euk-VirEquid_alphaherpesvirus_3
ribonucleotide_reductase_subunit_2__YP_009054923__Equid_alphaherpesvirus_3__80341
Identity
- Accession:
- YP_009054923 ↗
- Protein ID:
- ribonucleotide_reductase_subunit_2
- Kingdom:
- euk
Quality
88.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
Equid_alphaherpesvirus_3
TaxID: 80341
Cluster
View cluster (59 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 22-226
Domain cluster:
rep: ribonucleotide_reductase_subunit_2__YP_009052007__Elephant_endotheliotropic_herpesvirus_5__768738__D11-211
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00268.28 best | Ribonuc_red_sm | 156.5 | 1.40e-45 | 100.0% | 71.9% |
D2
medium
residues 227-292
Domain cluster:
rep: ORF54__NP_733908__Callitrichine_gammaherpesvirus_3__106331__D213-276
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4a5dB00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.93 | 70.0 | 4.62e-01 | 80.3% | 22.4% |
| 1h0oA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.86 | 75.0 | 4.73e-01 | 97.0% | 21.2% |
| 5olkB01 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.84 | 79.0 | 5.02e-01 | 100.0% | 24.4% |
| 2aniA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.84 | 71.0 | 4.46e-01 | 97.0% | 18.9% |
| 4bmoA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.82 | 72.0 | 4.58e-01 | 98.5% | 21.4% |
| 1biqA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.80 | 72.0 | 4.51e-01 | 100.0% | 19.7% |
| 3vm9A02 | 6.10.140.2110 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 51.0 | 5.45e-01 | 72.7% | 89.5% |
| 3geeA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.67 | 45.0 | 3.43e-01 | 71.2% | 35.1% |
| 3gwlA00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.66 | 48.0 | 4.14e-01 | 81.8% | 49.1% |
| 1vpdA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.65 | 45.0 | 3.58e-01 | 71.2% | 91.6% |
| 1knzA01 | 6.10.280.20 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Rotavirus non-structural protein NSP3, N-terminal domain | 0.64 | 45.0 | 3.89e-01 | 72.7% | 49.0% |
| 1oqcA00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.63 | 48.0 | 4.03e-01 | 81.8% | 80.4% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.62 | 46.0 | 3.38e-01 | 81.8% | 49.2% |
| 4cmyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 49.0 | 3.75e-01 | 87.9% | 77.3% |
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 48.0 | 3.93e-01 | 90.9% | 92.8% |
| 2zttA00 | 6.10.140.720 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 39.0 | 3.86e-01 | 78.8% | 60.3% |
| 3umbA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.60 | 45.0 | 4.28e-01 | 81.8% | 75.9% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 51.0 | 3.76e-01 | 100.0% | 72.6% |
| 2w01B00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.59 | 48.0 | 3.58e-01 | 97.0% | 81.7% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 45.0 | 3.72e-01 | 81.8% | 76.9% |
| 5facA02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.57 | 40.0 | 2.84e-01 | 100.0% | 22.2% |
| 1hciA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 43.0 | 3.55e-01 | 81.8% | 74.6% |
| 5xdcB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.55 | 43.0 | 3.66e-01 | 86.4% | 97.3% |
| 2m63A00 | 1.25.40.780 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 46.0 | 3.62e-01 | 100.0% | 76.4% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.54 | 45.0 | 3.71e-01 | 93.9% | 75.0% |
| 1wynA01 | 1.10.418.10 | Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain | 0.53 | 41.0 | 3.47e-01 | 81.8% | 70.4% |
| 5xe7A01 | 1.20.140.160 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain | 0.53 | 44.0 | 3.60e-01 | 100.0% | 78.2% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.53 | 42.0 | 3.66e-01 | 86.4% | 68.6% |
| 2afaA00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.52 | 43.0 | 2.76e-01 | 100.0% | 27.2% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 41.0 | 3.47e-01 | 84.8% | 74.1% |
| 6ndsA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.52 | 43.0 | 2.91e-01 | 100.0% | 95.7% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.50 | 42.0 | 3.49e-01 | 90.9% | 66.7% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 151585 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.93 | 74.0 | 4.72e-01 | 84.8% | 20.5% |
| 162837 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.87 | 76.0 | 4.84e-01 | 98.5% | 21.5% |
| 2388926 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.84 | 76.0 | 4.82e-01 | 98.5% | 23.0% |
| 4481595 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.83 | 77.0 | 4.76e-01 | 100.0% | 21.2% |
| 4488174 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.83 | 75.0 | 4.67e-01 | 98.5% | 20.9% |
| 3470297 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.82 | 77.0 | 4.73e-01 | 100.0% | 20.3% |
| 4603349 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.82 | 75.0 | 4.59e-01 | 100.0% | 18.3% |
| 4026999 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.82 | 73.0 | 4.61e-01 | 100.0% | 20.6% |
| 3386562 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.81 | 74.0 | 4.59e-01 | 100.0% | 20.0% |
| 3968133 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.80 | 74.0 | 4.54e-01 | 100.0% | 18.9% |
| 4044429 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.68 | 55.0 | 3.75e-01 | 87.9% | 80.9% |
| 4936001 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.67 | 53.0 | 4.43e-01 | 86.4% | 66.1% |
| 4311479 | 507.1.1.1 ↗ | alpha arrays › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB | 0.67 | 43.0 | 3.29e-01 | 71.2% | 26.7% |
| 4427305 | 192.29.1.275 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › NB-LRR | 0.66 | 58.0 | 3.96e-01 | 100.0% | 68.6% |
| 4385627 | 109.4.1.218 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP | 0.64 | 48.0 | 3.21e-01 | 81.8% | 27.9% |
| 5031241 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.63 | 47.0 | 4.50e-01 | 81.8% | 97.5% |
| 3595737 | 109.4.1.218 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP | 0.62 | 50.0 | 3.82e-01 | 86.4% | 44.7% |
| 4959335 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.62 | 45.0 | 4.02e-01 | 78.8% | 72.6% |
| 3922379 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.61 | 41.0 | 3.50e-01 | 71.2% | 48.2% |
| 3166146 | 7110.1.1.1 ↗ | alpha arrays › Helical insertion of YcjX stress protein › Helical insertion of YcjX stress protein › Helical insertion of YcjX stress protein › DUF463 | 0.61 | 49.0 | 3.91e-01 | 87.9% | 48.1% |
| 3957488 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.59 | 42.0 | 3.82e-01 | 75.8% | 85.6% |
| 3352250 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.58 | 46.0 | 4.22e-01 | 84.8% | 83.5% |
| 3532664 | 3755.3.1.391 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › USHBP1_PDZ-bd | 0.58 | 40.0 | 3.18e-01 | 72.7% | 72.9% |
| 4168571 | 186.1.1.1 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 | 0.55 | 45.0 | 3.87e-01 | 93.9% | 92.7% |
| 3739120 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 46.0 | 3.47e-01 | 95.5% | 59.4% |
| 4657272 | 186.1.1.1 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 | 0.54 | 45.0 | 3.96e-01 | 97.0% | 93.3% |
| 4946658 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.53 | 45.0 | 3.62e-01 | 100.0% | 73.8% |
| 4979930 | 2003.1.3.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain | 0.53 | 41.0 | 2.52e-01 | 83.3% | 55.4% |
| 3457403 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.52 | 40.0 | 3.44e-01 | 92.4% | 60.0% |
| 3607111 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 42.0 | 3.13e-01 | 92.4% | 73.7% |