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ribonucleotide_reductase_subunit_2a

Euk-Vir

Epinotia_aporema_granulovirus

ribonucleotide_reductase_subunit_2a__YP_006908511__Epinotia_aporema_granulovirus__166056

Identity

Accession:
YP_006908511 ↗
Protein ID:
ribonucleotide_reductase_subunit_2a
Kingdom:
euk

Quality

74.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 57-168_197-252
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00268.28 best Ribonuc_red_sm 41.7 1.30e-10 66.7% 38.1%
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4bmoA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.90 87.0 7.03e-01 100.0% 72.4%
1h0oA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.90 87.0 7.00e-01 100.0% 70.1%
1biqA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.90 86.0 6.60e-01 100.0% 69.1%
2aniA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.89 86.0 6.75e-01 100.0% 68.8%
6eboA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.89 85.0 6.72e-01 100.0% 65.0%
2rccA01 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.87 84.0 7.04e-01 100.0% 80.3%
5olkB01 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.86 82.0 6.74e-01 100.0% 74.2%
4a5dB00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.82 80.0 6.97e-01 100.0% 73.3%
1mhyD00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.80 75.0 5.21e-01 100.0% 41.8%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 59.0 6.25e-01 78.0% 96.7%
4mudC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 61.0 5.56e-01 86.3% 74.1%
2yw6B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.72 55.0 5.83e-01 78.6% 100.0%
3t9jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.72 51.0 5.52e-01 72.6% 100.0%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.72 57.0 5.74e-01 83.3% 92.4%
1lb3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 55.0 5.51e-01 81.0% 91.6%
1nfvA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 55.0 5.52e-01 81.5% 87.0%
1z6oA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 55.0 5.05e-01 82.7% 79.2%
1otvA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.68 53.0 4.61e-01 81.0% 67.7%
3vvaA00 1.20.1260.140 Mainly Alpha › Up-down Bundle › Ferritin › Alternative oxidase 0.68 57.0 4.84e-01 88.7% 84.2%
1uddA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.67 52.0 4.80e-01 81.5% 75.3%
3no6A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.65 52.0 4.62e-01 83.3% 71.5%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 40.0 4.33e-01 76.2% 71.8%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 40.0 4.78e-01 80.4% 95.3%
3dyjA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.61 40.0 4.04e-01 79.8% 65.1%
3oqlC00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.60 55.0 4.86e-01 100.0% 88.8%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 45.0 4.24e-01 77.4% 91.5%
4gytA00 1.20.120.740 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YgfB uncharacterised protein family PF03695 0.59 33.0 3.30e-01 74.4% 49.7%
1j77A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.59 46.0 4.33e-01 83.3% 68.3%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 45.0 3.80e-01 81.5% 86.5%
3iqtA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.57 32.0 3.74e-01 81.5% 77.2%
3pivA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.57 41.0 4.24e-01 72.6% 90.4%
4ib4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.57 42.0 3.51e-01 76.2% 95.4%
7twaC00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.55 50.0 4.61e-01 100.0% 88.2%
3vw7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 44.0 3.67e-01 85.1% 99.6%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 39.0 3.43e-01 75.6% 72.7%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.53 31.0 3.38e-01 97.0% 66.7%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 40.0 3.56e-01 79.2% 79.3%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 40.0 3.47e-01 81.0% 92.1%
6tejB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.52 38.0 3.15e-01 76.2% 82.8%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.52 40.0 3.20e-01 81.0% 98.5%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3470297 150.1.2.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase 0.90 88.0 6.71e-01 100.0% 60.3%
4603349 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 87.0 6.55e-01 100.0% 57.2%
4481595 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 87.0 6.70e-01 100.0% 63.0%
1726039 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 87.0 6.64e-01 100.0% 69.3%
3274715 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 74.0 6.67e-01 83.9% 79.5%
436631 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 87.0 6.53e-01 100.0% 66.8%
5009507 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 86.0 6.69e-01 100.0% 65.5%
151585 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.89 86.0 7.16e-01 100.0% 76.1%
56518 150.1.2.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase 0.89 86.0 6.59e-01 100.0% 69.3%
5009513 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.89 85.0 6.66e-01 100.0% 66.3%
4267558 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.89 85.0 6.67e-01 100.0% 65.5%
3284093 150.1.1.132 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › AurF 0.83 79.0 6.22e-01 100.0% 67.5%
3959806 150.1.2.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase 0.83 79.0 6.16e-01 100.0% 67.1%
5009415 150.1.2.20 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Rubrerythrin 0.81 76.0 6.20e-01 100.0% 70.2%
3756278 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.69 56.0 5.36e-01 100.0% 73.8%
3802402 633.22.1.0 alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) 0.65 48.0 5.04e-01 95.8% 83.9%
3195065 6155.1.1.6 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 0.62 56.0 5.02e-01 98.2% 79.1%
3913234 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.60 46.0 5.08e-01 95.8% 97.8%
3200515 5050.1.1.26 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot 0.57 42.0 4.13e-01 73.8% 99.4%
5014010 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 39.0 3.62e-01 70.8% 74.0%
2701721 628.1.1.1 alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD 0.56 33.0 3.64e-01 91.7% 69.0%
3228302 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.55 39.0 4.51e-01 90.5% 100.0%
3580332 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 40.0 4.22e-01 94.0% 83.2%
5001604 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 38.0 3.63e-01 74.4% 79.0%
3485769 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.50 36.0 3.50e-01 79.2% 63.6%
D2 medium residues 169-196_253-320
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 50.0 4.28e-01 96.9% 96.2%
3etvA02 1.20.58.2230 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Retrograde transport protein Dsl1, N-terminal domain 0.57 41.0 3.22e-01 78.1% 55.8%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.57 46.0 3.08e-01 89.6% 42.1%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.56 39.0 4.04e-01 84.4% 79.3%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.55 42.0 4.03e-01 82.3% 93.9%
3ehmA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 45.0 3.15e-01 96.9% 39.5%
3h4cA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.50 37.0 3.70e-01 77.1% 87.5%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3283457 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.61 37.0 3.72e-01 70.8% 58.0%
5038830 375.1.1.26 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 0.57 39.0 3.92e-01 84.4% 68.0%
3703267 101.1.10.1 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.57 45.0 4.18e-01 83.3% 76.7%
3906030 5001.1.1.3 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2 0.55 42.0 3.25e-01 82.3% 89.1%
3515526 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.54 43.0 3.89e-01 87.5% 68.1%
3409412 101.1.10.19 alpha arrays › HTH › HTH › Cyclin-like › ORC6_2nd 0.53 36.0 3.66e-01 70.8% 75.8%