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rifcsphigho2-12_scaffold_combined_curated_prodigal-single.1__X__X__00140

Bact-Vir

rifcsphigho2-12_scaffold_combined_curated_prodigal-single.1__X__X__00140

Identity

Kingdom:
phage

Quality

84.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 43-156_290-320
PDB
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4lx3A00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.83 55.0 6.54e-01 91.0% 96.0%
2lwyA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.75 67.0 6.90e-01 94.5% 97.1%
1am2A00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.75 68.0 6.25e-01 94.5% 98.9%
4e2tB00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.75 67.0 6.36e-01 94.5% 99.4%
1at0A00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.75 68.0 6.87e-01 95.9% 99.3%
2lcjA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.74 67.0 6.07e-01 94.5% 99.5%
4o1sA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.74 67.0 6.31e-01 95.2% 97.1%
1mi8A00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.74 67.0 6.80e-01 95.9% 97.9%
2imzA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.73 66.0 6.70e-01 93.8% 100.0%
5o9iA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.73 65.0 6.13e-01 94.5% 99.4%
2cw8A01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.73 65.0 6.13e-01 94.5% 99.4%
2jmzA01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.72 64.0 6.11e-01 94.5% 99.4%
6zgqA01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.72 64.0 6.40e-01 93.8% 100.0%
6vgwA01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.67 61.0 6.20e-01 96.6% 100.0%
3k6yA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.52 32.0 3.63e-01 90.3% 82.2%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5028312 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.78 70.0 7.17e-01 95.9% 97.1%
5028788 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.77 72.0 7.33e-01 96.6% 100.0%
3257888 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.77 71.0 7.01e-01 95.2% 99.3%
4978263 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.77 71.0 6.72e-01 95.9% 97.0%
5030213 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.76 70.0 6.96e-01 96.6% 94.7%
4993128 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.76 69.0 6.69e-01 95.9% 98.1%
3949431 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.76 69.0 6.83e-01 94.5% 99.3%
259963 69.1.1.3 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › PT-HINT 0.75 67.0 6.90e-01 94.5% 97.1%
5035476 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.75 68.0 6.59e-01 94.5% 97.5%
4983458 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.75 67.0 6.43e-01 93.8% 98.2%
4979524 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.75 70.0 5.68e-01 97.2% 99.6%
4984220 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.75 68.0 6.62e-01 93.8% 100.0%
4982797 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.75 69.0 6.94e-01 95.9% 98.6%
5022295 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.75 69.0 6.61e-01 96.6% 99.4%
4943231 69.1.1.16 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › ATP-synt_ab 0.75 68.0 6.30e-01 95.9% 98.3%
4392318 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.75 67.0 6.11e-01 93.8% 99.5%
4975971 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.75 64.0 6.76e-01 93.8% 100.0%
4940451 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.75 66.0 6.85e-01 93.1% 99.3%
5012699 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.75 67.0 6.30e-01 93.8% 99.4%
4998392 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.75 69.0 6.55e-01 95.9% 100.0%
4975578 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 67.0 5.31e-01 95.2% 56.7%
1291738 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 54.0 6.26e-01 91.7% 99.1%
4977673 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 67.0 5.65e-01 94.5% 99.1%
5012957 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.74 68.0 6.31e-01 95.9% 98.9%
182766 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.74 67.0 6.07e-01 94.5% 99.5%
5065032 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.74 68.0 6.44e-01 95.2% 100.0%
4999902 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 67.0 6.78e-01 95.2% 100.0%
3495262 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.74 68.0 6.29e-01 97.2% 96.7%
5028299 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.74 66.0 6.44e-01 93.8% 98.1%
4872043 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 68.0 6.72e-01 96.6% 98.0%
4993480 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 67.0 6.47e-01 95.9% 99.4%
4993808 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 67.0 6.74e-01 95.2% 100.0%
4993853 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 66.0 6.30e-01 94.5% 99.4%
2524072 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.74 66.0 6.23e-01 94.5% 98.2%
4992651 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 67.0 6.39e-01 95.9% 97.0%
4975503 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.74 66.0 6.11e-01 95.2% 99.4%
5029540 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.73 65.0 6.30e-01 93.8% 98.8%
3604383 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.73 65.0 5.63e-01 93.8% 98.1%
5066389 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.73 67.0 6.03e-01 96.6% 99.5%
4993454 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.73 66.0 5.54e-01 95.9% 98.3%
4243055 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.73 69.0 6.18e-01 100.0% 89.7%
3518586 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.73 69.0 6.05e-01 100.0% 91.7%
4948016 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.73 64.0 6.33e-01 91.7% 97.3%
2675767 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.73 66.0 6.50e-01 95.9% 98.1%
5031634 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.73 67.0 6.46e-01 97.2% 96.9%
5024341 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.73 66.0 6.04e-01 95.9% 97.8%
4993581 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.73 66.0 6.22e-01 95.9% 97.1%
4971412 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.73 64.0 5.88e-01 92.4% 100.0%
4983616 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.73 66.0 6.19e-01 95.2% 99.4%
5009161 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.73 66.0 5.09e-01 96.6% 99.3%
3604113 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.73 65.0 6.59e-01 95.2% 99.3%
4979631 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.72 65.0 6.45e-01 95.2% 100.0%
5014854 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.72 65.0 5.61e-01 95.9% 98.1%
5029355 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.72 64.0 6.39e-01 94.5% 100.0%
3603108 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.72 65.0 6.56e-01 95.9% 97.9%
4997604 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.71 64.0 6.10e-01 95.9% 97.1%
3517362 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.71 64.0 6.51e-01 95.9% 100.0%
3604439 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.71 64.0 6.03e-01 95.9% 98.2%
4322985 2004.1.1.14 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU 0.71 66.0 4.86e-01 100.0% 63.4%
4943244 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.71 62.0 5.90e-01 93.8% 98.8%
5031914 69.1.1.4 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing 0.70 64.0 5.84e-01 96.6% 95.7%
5052154 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.70 63.0 6.04e-01 95.2% 99.4%
4948019 69.1.1.17 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › MCM 0.70 63.0 5.94e-01 96.6% 97.7%
4971400 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.70 66.0 5.10e-01 100.0% 69.5%
4978364 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.67 51.0 5.66e-01 88.3% 98.3%
4999896 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.67 52.0 5.63e-01 91.7% 93.6%
4932851 69.1.1.1 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Hint 0.66 56.0 5.80e-01 95.9% 97.0%
4999893 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.64 48.0 5.41e-01 91.7% 100.0%
4970868 69.1.1.0 beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint 0.62 51.0 5.51e-01 91.0% 100.0%
3655111 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.55 38.0 4.32e-01 91.7% 93.6%
4012379 4.18.1.1 beta barrels › SH3 › Plus3 › Plus3 › Plus-3 0.54 30.0 3.34e-01 80.7% 67.8%
3635435 4.18.1.1 beta barrels › SH3 › Plus3 › Plus3 › Plus-3 0.53 33.0 3.33e-01 87.6% 61.4%
D2 medium residues 157-217_232-289
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF14527.12 best LAGLIDADG_WhiA 30.8 3.60e-07 75.6% 90.3%
PF14528.12 LAGLIDADG_3 34.1 3.50e-08 62.2% 97.6%
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dq3A04 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.81 64.0 6.53e-01 81.5% 90.4%
8dy9I01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.80 57.0 4.59e-01 72.3% 44.7%
2ex5A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.80 62.0 5.02e-01 79.8% 58.0%
3ko2A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.79 61.0 5.50e-01 81.5% 72.7%
2dchX01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.78 52.0 5.89e-01 70.6% 87.1%
4yhxA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.77 59.0 5.53e-01 79.0% 81.6%
2dchX02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.77 58.0 6.07e-01 79.0% 92.8%
3hyiA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.77 59.0 4.96e-01 79.8% 49.7%
5a72A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.77 61.0 5.50e-01 83.2% 73.2%
4lq0A02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.76 58.0 5.36e-01 79.0% 79.6%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.75 35.0 4.61e-01 70.6% 80.3%
1af5A00 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.74 58.0 5.71e-01 82.4% 87.3%
7qssA01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.73 54.0 4.56e-01 75.6% 50.0%
3c0wA02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.73 51.0 5.44e-01 71.4% 91.3%
1ef0B02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.72 51.0 4.32e-01 72.3% 87.2%
6vudA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.62 36.0 4.39e-01 84.9% 90.7%
1dd5A02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.62 37.0 4.52e-01 85.7% 93.3%
5mmjh01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.59 34.0 4.10e-01 71.4% 89.3%
3zcoA00 1.10.10.2450 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.58 41.0 4.07e-01 73.1% 97.6%
2ln3A00 3.30.110.140 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › 0.55 34.0 3.91e-01 79.8% 85.5%
3pqkA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 39.0 4.16e-01 72.3% 90.9%
2ebbA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.55 38.0 4.18e-01 70.6% 89.6%
1js3A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 38.0 4.15e-01 70.6% 91.8%
1yyvB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 38.0 3.95e-01 72.3% 87.5%
5eriA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 37.0 3.46e-01 70.6% 56.2%
4hqeA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 37.0 3.94e-01 71.4% 86.7%
2fswA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 38.0 4.01e-01 72.3% 87.3%
5e1wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 37.0 3.31e-01 70.6% 49.4%
2zkzC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 36.0 4.06e-01 73.1% 95.4%
5hs7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 36.0 3.88e-01 71.4% 89.8%
3db0B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.51 36.0 3.62e-01 73.1% 85.5%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4937054 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.91 63.0 6.78e-01 71.4% 89.5%
5028488 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.89 66.0 6.99e-01 75.6% 94.3%
3950413 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.88 67.0 7.00e-01 79.0% 90.9%
5029252 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.86 65.0 6.52e-01 77.3% 85.8%
5022297 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.83 59.0 6.61e-01 76.5% 91.6%
4934140 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.82 61.0 6.28e-01 77.3% 80.9%
4943246 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.81 61.0 6.61e-01 77.3% 92.0%
4979626 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.81 66.0 6.37e-01 84.9% 92.3%
4559752 242.1.1.6 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_WhiA 0.80 58.0 6.64e-01 78.2% 97.8%
4996524 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.80 60.0 5.01e-01 85.7% 47.7%
4993483 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.80 61.0 6.54e-01 82.4% 90.5%
4979525 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.80 61.0 5.03e-01 79.0% 48.7%
3604140 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.79 69.0 5.85e-01 91.6% 83.8%
4946208 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.79 55.0 6.25e-01 72.3% 94.4%
4288172 242.1.1.6 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_WhiA 0.79 61.0 5.94e-01 80.7% 76.2%
4997606 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.78 68.0 6.14e-01 90.8% 80.0%
3205225 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.78 60.0 6.28e-01 79.8% 89.1%
3738330 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.78 58.0 5.49e-01 77.3% 78.6%
5023789 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.78 50.0 5.87e-01 71.4% 91.8%
5023543 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.78 58.0 6.25e-01 79.0% 91.0%
5023542 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.78 48.0 5.94e-01 70.6% 98.7%
5028300 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.77 51.0 5.97e-01 72.3% 94.1%
4992480 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.77 53.0 6.02e-01 72.3% 92.2%
4938255 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.77 48.0 5.70e-01 70.6% 92.5%
1159602 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.77 58.0 6.04e-01 79.0% 92.0%
3603087 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.77 53.0 6.24e-01 71.4% 100.0%
4377946 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.77 61.0 5.91e-01 83.2% 89.2%
4096150 242.1.1.6 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_WhiA 0.77 59.0 5.87e-01 80.7% 78.4%
5012958 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.76 56.0 5.49e-01 76.5% 95.4%
4975576 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.76 55.0 6.30e-01 74.8% 98.9%
4626502 242.1.1.6 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_WhiA 0.76 59.0 5.85e-01 80.7% 78.4%
4971000 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.76 57.0 6.16e-01 77.3% 93.0%
4171345 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.76 52.0 5.82e-01 70.6% 95.8%
4122798 242.1.1.6 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_WhiA 0.76 59.0 6.30e-01 81.5% 95.2%
5028789 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.76 55.0 6.25e-01 74.8% 100.0%
5046394 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.76 52.0 5.96e-01 70.6% 97.8%
5012700 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.76 52.0 5.99e-01 74.8% 97.6%
5065185 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.75 52.0 5.89e-01 70.6% 96.7%
5066572 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.75 56.0 6.00e-01 84.0% 86.7%
3251998 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.75 56.0 5.92e-01 76.5% 90.5%
3282307 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.75 52.0 5.78e-01 70.6% 95.8%
3206012 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.75 56.0 6.11e-01 78.2% 95.0%
4993809 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.75 54.0 5.90e-01 75.6% 89.0%
4464568 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.75 55.0 6.04e-01 77.3% 91.0%
3603293 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.74 57.0 5.85e-01 79.8% 88.7%
5029853 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.74 55.0 5.52e-01 76.5% 86.7%
4997605 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.74 54.0 5.89e-01 75.6% 91.0%
4474382 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.74 60.0 5.93e-01 84.9% 89.6%
5052155 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.72 62.0 5.41e-01 91.6% 81.7%
4979624 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.72 53.0 5.50e-01 76.5% 92.7%
4479273 242.1.1.1 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_1 0.72 54.0 5.32e-01 79.8% 86.2%
4978474 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.70 60.0 5.69e-01 89.1% 89.6%
4978265 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.69 58.0 5.21e-01 89.1% 81.2%
4996403 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.68 44.0 4.99e-01 84.0% 86.7%
4200948 242.1.1.2 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 0.67 46.0 4.99e-01 74.8% 84.0%
4405102 242.1.1.8 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3, Intein_splicing 0.66 56.0 4.08e-01 89.9% 37.3%
3659848 320.4.1.0 a+b two layers › R3H domain-like › PUB domain › PUB domain 0.61 42.0 4.06e-01 70.6% 80.7%
5014006 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.59 36.0 4.25e-01 79.0% 85.9%
4152393 305.2.1.1 a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.58 40.0 4.25e-01 71.4% 85.7%
3185841 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.54 31.0 3.87e-01 82.4% 94.3%
4006693 3012.1.1.0 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.54 35.0 4.10e-01 92.4% 92.9%
3737998 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.53 36.0 4.19e-01 84.0% 97.6%
3589189 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 37.0 3.71e-01 79.0% 69.6%
4094836 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.52 39.0 3.45e-01 94.1% 53.3%
D3 medium residues 321-372
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17975.7 best RNR_Alpha 36.0 1.20e-08 100.0% 62.4%
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.88 81.0 4.55e-01 100.0% 12.5%
2wghA00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.78 69.0 3.85e-01 100.0% 7.9%
3ugjA02 1.10.8.750 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Phosphoribosylformylglycinamidine synthase, linker domain 0.71 52.0 4.97e-01 82.7% 66.1%
1icrA00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.71 53.0 3.45e-01 80.8% 26.4%
4i8oA03 1.10.8.1130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial toxin RNase RnlA/LsoA, C-terminal Dmd-binding domain 0.65 45.0 4.22e-01 73.1% 71.6%
1jwjA01 3.90.340.10 Alpha Beta › Alpha-Beta Complex › Nitric Oxide Synthase; Chain A, domain 1 › Nitric Oxide Synthase; Chain A, domain 1 0.64 52.0 3.71e-01 92.3% 57.4%
2qvwB05 1.10.1740.150 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.64 45.0 3.94e-01 92.3% 50.0%
2isyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 50.0 3.83e-01 96.2% 34.8%
2gz4A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.64 53.0 3.67e-01 100.0% 62.5%
2ig3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 54.0 4.15e-01 100.0% 76.4%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.62 50.0 4.27e-01 90.4% 87.2%
1k8kA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.62 48.0 4.10e-01 90.4% 100.0%
4fqnC00 1.20.1160.20 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › 0.61 48.0 4.21e-01 90.4% 75.3%
2co9A00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.61 42.0 3.47e-01 76.9% 38.2%
7oufB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.60 43.0 3.20e-01 78.8% 29.5%
3besR03 6.10.140.1480 Special › Helix non-globular › Helix Hairpins › 0.60 41.0 4.09e-01 73.1% 71.4%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.59 46.0 3.61e-01 88.5% 45.2%
7pl7A01 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.59 49.0 3.64e-01 100.0% 97.4%
1wgfA01 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.58 42.0 4.20e-01 78.8% 77.4%
3l4aA00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.58 42.0 3.30e-01 80.8% 43.8%
4griA04 1.10.8.70 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutamate-tRNA synthetase, class I, anticodon-binding domain 1 0.58 44.0 4.47e-01 92.3% 86.8%
1l9lA00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.56 38.0 3.53e-01 73.1% 63.5%
1j09A04 1.10.8.70 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutamate-tRNA synthetase, class I, anticodon-binding domain 1 0.56 40.0 4.13e-01 82.7% 87.5%
7r97A01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.56 46.0 3.44e-01 98.1% 64.9%
1reoA03 1.10.405.10 Mainly Alpha › Orthogonal Bundle › Guanine Nucleotide Dissociation Inhibitor; domain 1 › Guanine Nucleotide Dissociation Inhibitor, domain 1 0.56 38.0 3.20e-01 75.0% 84.2%
2m3aA00 1.10.10.1900 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Knl-2 Myb-like DNA-binding domain-like 0.52 33.0 3.13e-01 71.2% 49.3%
1qrvA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.51 41.0 3.76e-01 96.2% 69.9%
3fvvA02 1.20.1440.100 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function 0.51 41.0 3.71e-01 94.2% 85.3%
2n1rA00 1.10.150.90 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 0.50 39.0 3.12e-01 98.1% 71.6%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5034061 148.1.3.400 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Ribonuc_red_lgN 0.81 73.0 4.84e-01 100.0% 31.1%
4976420 1074.1.1.0 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases 0.80 72.0 5.62e-01 100.0% 58.1%
3515890 1074.1.1.1 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_lgN 0.78 69.0 5.17e-01 100.0% 96.8%
3970179 103.6.1.0 alpha arrays › RuvA-C › FGAM synthase PurL, linker domain › FGAM synthase PurL, linker domain 0.73 51.0 4.92e-01 75.0% 65.0%
3221809 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.71 48.0 4.61e-01 73.1% 61.7%
4050022 101.35.1.4 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3 0.69 45.0 4.50e-01 71.2% 63.6%
5012860 4957.1.1.0 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit 0.66 51.0 4.08e-01 84.6% 43.0%
3915335 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.66 49.0 3.30e-01 92.3% 19.5%
5024095 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.64 53.0 3.48e-01 92.3% 71.3%
3928496 143.1.1.0 alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain 0.62 47.0 4.53e-01 84.6% 73.3%
3739025 103.1.1.57 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › GDH2_N 0.61 49.0 4.55e-01 94.2% 75.7%
3410442 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.61 47.0 3.61e-01 86.5% 44.0%
3385104 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.61 48.0 4.30e-01 94.2% 62.5%
3989133 2010.1.1.3 a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain › EIIA-man 0.61 43.0 3.23e-01 76.9% 79.3%
3222778 103.15.1.1 alpha arrays › RuvA-C › Mitoribosomal protein mS23 › Mitoribosomal protein mS23 › MRP-S23 0.58 41.0 3.26e-01 80.8% 32.8%
3609451 108.1.1.73 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5+EF-hand_7 0.58 45.0 3.94e-01 88.5% 69.4%
5073637 212.1.1.0 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.55 39.0 3.12e-01 86.5% 33.6%
3711589 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.54 44.0 3.98e-01 92.3% 65.3%
3211834 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.54 39.0 3.45e-01 96.2% 51.3%
1176214 108.2.1.1 alpha arrays › EF-hand › Insect pheromone/odorant-binding proteins › Insect pheromone/odorant-binding proteins › PBP_GOBP 0.54 45.0 3.42e-01 96.2% 73.0%
3572021 190.1.1.3 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box_2 0.54 42.0 4.03e-01 94.2% 73.8%
3414570 190.1.1.5 alpha arrays › HMG-box-like › HMG-box › HMG-box › Protamine_like 0.53 42.0 3.88e-01 98.1% 73.3%
144750 150.3.1.3 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL6 0.52 43.0 3.08e-01 98.1% 55.4%
3689474 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.51 40.0 3.41e-01 94.2% 53.0%
3583002 101.1.2.265 alpha arrays › HTH › HTH › winged helix domain › Stork_head 0.51 41.0 3.81e-01 92.3% 95.7%
3593415 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.51 41.0 3.63e-01 92.3% 70.0%
338972 4966.1.1.2 alpha arrays › inserted helical bundle subdomain in T7 RNA polymerase › inserted helical bundle subdomain in T7 RNA polymerase › inserted helical bundle subdomain in T7 RNA polymerase › vRNAP_plug 0.50 43.0 3.45e-01 98.1% 87.7%
D4 medium residues 373-424_537-636_903-922
PDB
D5 medium residues 425-536
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF21995.2 best RNR-II_ins_dom 38.5 1.60e-09 73.2% 67.3%
D6 medium residues 637-742
PDB
D7 medium residues 743-804_874-902
PDB
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1l1lA03 3.90.1390.10 Alpha Beta › Alpha-Beta Complex › b-12 dependent (class ii) ribonucleotide reductase, chain A, domain 3 › b-12 dependent (class ii) ribonucleotide reductase, chain A, domain 3 0.85 74.0 7.39e-01 91.2% 93.6%
1nxiA00 3.30.70.970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RraB-like 0.59 44.0 3.88e-01 78.0% 80.3%
3ahpA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 42.0 4.05e-01 82.4% 97.2%
2ypyA00 3.30.70.390 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Epstein Barr virus nuclear antigen-1, DNA-binding domain 0.54 42.0 3.75e-01 85.7% 79.1%
1l2mA00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.53 43.0 3.98e-01 87.9% 89.0%
4e98C00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 41.0 3.97e-01 82.4% 98.1%
4ozjA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 41.0 4.01e-01 85.7% 90.4%
5gxxA02 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.51 37.0 3.19e-01 78.0% 80.9%
2vzyC00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 43.0 3.45e-01 94.5% 89.9%
2efpA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.51 35.0 3.47e-01 71.4% 84.7%
3mgjA00 3.30.70.2690 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › LOR/SDH bifunctional enzyme, conserved domain 0.50 36.0 3.58e-01 75.8% 100.0%
6vh5C03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.50 37.0 3.80e-01 80.2% 97.8%
1kn6A00 3.30.70.850 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8, pro-domain 0.50 32.0 3.52e-01 85.7% 80.8%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5051775 2500.1.1.9 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › RNR-II_ins_dom 0.91 79.0 4.72e-01 89.0% 29.0%
4087732 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.90 86.0 5.19e-01 100.0% 32.7%
3275621 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.88 84.0 5.15e-01 98.9% 34.2%
4208725 2500.1.1.0 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.83 78.0 4.73e-01 100.0% 30.4%
3421380 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.59 42.0 4.26e-01 73.6% 94.4%
4399086 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.57 40.0 4.19e-01 75.8% 95.3%
3590219 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.56 41.0 4.18e-01 78.0% 93.3%
4963170 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.56 41.0 4.21e-01 79.1% 94.4%
5066425 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.56 39.0 4.15e-01 73.6% 100.0%
4965941 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.55 42.0 4.03e-01 83.5% 93.6%
4373827 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.55 42.0 4.27e-01 82.4% 97.7%
4333414 304.24.1.1 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C 0.54 38.0 3.85e-01 73.6% 84.0%
3591960 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.54 37.0 3.79e-01 72.5% 95.6%
4030243 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.52 41.0 3.94e-01 84.6% 95.2%
3587356 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.52 40.0 4.05e-01 83.5% 100.0%
4972691 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.52 38.0 3.78e-01 79.1% 94.0%
4173219 304.8.1.1 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Thr_dehydrat_C 0.52 37.0 3.72e-01 72.5% 92.2%
4638999 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.52 36.0 3.83e-01 73.6% 97.5%
3978701 304.54.1.1 a+b two layers › Alpha-beta plaits › CcmK-like › CcmK-like › BMC 0.52 37.0 3.78e-01 74.7% 97.8%
4020643 304.8.1.1 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Thr_dehydrat_C 0.51 35.0 3.52e-01 71.4% 94.7%
4927807 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.51 34.0 3.57e-01 70.3% 94.1%
4524153 304.22.1.1 a+b two layers › Alpha-beta plaits › Urease metallochaperone UreE, C-terminal domain › Urease metallochaperone UreE, C-terminal domain › UreE_C 0.51 38.0 3.93e-01 79.1% 89.4%
4987678 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.51 37.0 3.76e-01 78.0% 94.4%
3108806 304.54.1.1 a+b two layers › Alpha-beta plaits › CcmK-like › CcmK-like › BMC 0.51 35.0 3.53e-01 71.4% 92.3%
3365659 304.8.1.1 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Thr_dehydrat_C 0.51 35.0 3.54e-01 71.4% 93.3%
4220405 213.1.1.3 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Autoind_synth 0.50 43.0 3.33e-01 94.5% 92.7%
D8 medium residues 805-873
PDB
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.85 79.0 4.60e-01 100.0% 29.2%
2yk4A01 3.30.370.20 Alpha Beta › 2-Layer Sandwich › Barnase; Chain D › 0.69 53.0 5.08e-01 91.3% 70.7%
4pqgA03 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.67 54.0 4.06e-01 94.2% 35.6%
5ddtA00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.66 54.0 3.76e-01 91.3% 32.3%
1y44A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.66 57.0 3.85e-01 100.0% 45.1%
4x7rA03 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.65 53.0 4.04e-01 95.7% 37.3%
6jtdA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.65 54.0 3.67e-01 94.2% 31.2%
4obxA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 56.0 3.90e-01 98.6% 37.4%
7kx9A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 54.0 4.31e-01 97.1% 66.7%
5jldA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.63 49.0 3.45e-01 87.0% 97.9%
4cvhA01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.63 53.0 3.68e-01 94.2% 29.6%
4gl8A03 3.10.105.10 Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 0.62 48.0 3.50e-01 87.0% 57.8%
3dlbA04 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.62 50.0 3.88e-01 95.7% 58.9%
1narA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.62 53.0 3.56e-01 100.0% 63.7%
4mp8A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 48.0 3.63e-01 85.5% 44.5%
1pzmA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 46.0 3.54e-01 84.1% 35.3%
4lg1B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 51.0 3.69e-01 97.1% 38.5%
4icsA01 3.40.1830.10 Alpha Beta › 3-Layer(aba) Sandwich › Thermophilic metalloprotease-like › Thermophilic metalloprotease (M29) 0.60 45.0 3.39e-01 85.5% 31.1%
7zr3A01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.60 51.0 3.40e-01 100.0% 72.8%
4kt7A00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.60 50.0 3.50e-01 94.2% 30.8%
1edzA02 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.59 40.0 3.37e-01 72.5% 45.0%
4j0eA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 47.0 3.44e-01 89.9% 50.5%
4u1qA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 50.0 3.74e-01 98.6% 39.0%
2vdwG00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 51.0 3.45e-01 100.0% 30.1%
2rffA00 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.59 33.0 2.84e-01 88.4% 34.2%
4y7uA00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.58 49.0 3.49e-01 95.7% 77.2%
3do8A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 45.0 3.69e-01 100.0% 43.7%
2vshA00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.58 47.0 3.44e-01 94.2% 76.2%
5dh0A01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.58 50.0 4.29e-01 100.0% 68.4%
2jfzA02 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 46.0 3.90e-01 88.4% 62.7%
2dt8A02 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.58 47.0 3.95e-01 95.7% 56.9%
3wxmB02 3.30.420.60 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 0.58 45.0 3.84e-01 88.4% 77.0%
3h7aA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 48.0 3.53e-01 100.0% 72.6%
2d13A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.57 43.0 3.75e-01 88.4% 50.9%
2o2gA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 48.0 3.52e-01 100.0% 88.9%
1j09A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.57 46.0 3.94e-01 92.8% 96.7%
6dv2G02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 44.0 3.39e-01 91.3% 50.5%
1dtnA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.56 47.0 3.38e-01 98.6% 47.4%
4s1wB02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.56 45.0 3.63e-01 92.8% 65.8%
2z1dA01 3.40.50.11750 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HypD, alpha/beta domain 1 0.55 43.0 3.51e-01 88.4% 53.2%
1f2vA00 3.40.50.10230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase 0.55 44.0 3.25e-01 92.8% 45.0%
3ry7A00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.55 42.0 2.87e-01 88.4% 27.4%
1utbB01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.55 41.0 3.44e-01 98.6% 45.3%
4pioA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 44.0 3.45e-01 100.0% 46.4%
2p9bA02 3.30.110.90 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Amidohydrolase 0.53 39.0 3.71e-01 84.1% 65.1%
2mzbA00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.53 42.0 3.19e-01 92.8% 41.3%
3pl5A03 3.30.1180.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › 0.53 43.0 3.73e-01 95.7% 58.7%
7febA03 3.40.50.12790 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › FHIPEP family, domain 4 0.52 40.0 3.69e-01 85.5% 80.4%
3fefA00 3.90.1820.10 Alpha Beta › Alpha-Beta Complex › LDH C-terminal domain-like › AglA-like glucosidase 0.52 43.0 2.71e-01 98.6% 73.0%
4x9xA01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 41.0 3.43e-01 97.1% 94.6%
3o3mB02 3.40.50.11890 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 42.0 3.60e-01 97.1% 80.2%
4fypB00 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.51 42.0 3.08e-01 98.6% 70.1%
ECOD (67)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4992331 247.1.1.30 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 0.70 61.0 4.19e-01 100.0% 47.4%
4465856 247.1.1.33 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B, Lactamase_B_2, Anti-Pycsar_Apyc1 0.69 60.0 3.95e-01 100.0% 39.1%
3171720 2006.1.1.28 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › APP1_cat 0.69 56.0 3.97e-01 91.3% 91.6%
3737774 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.69 60.0 4.63e-01 98.6% 54.8%
4254890 247.1.1.30 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 0.66 56.0 3.70e-01 98.6% 39.4%
4956614 247.1.1.30 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 0.66 57.0 3.76e-01 100.0% 39.0%
4667650 7516.1.1.7 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › UDPGP 0.66 52.0 3.40e-01 89.9% 62.4%
4138173 247.1.1.33 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B, Lactamase_B_2, Anti-Pycsar_Apyc1 0.65 56.0 3.70e-01 100.0% 38.1%
4342487 247.1.1.30 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 0.64 54.0 3.63e-01 100.0% 38.7%
4139456 247.1.1.41 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B, Lactamase_B_4, Anti-Pycsar_Apyc1 0.64 54.0 3.64e-01 100.0% 40.5%
3503043 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.64 53.0 3.72e-01 97.1% 39.6%
4857936 2487.1.1.13 a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" › Ncstrn_small 0.63 45.0 3.26e-01 85.5% 24.5%
4952517 2002.1.1.77 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › RNase_P_p30 0.63 50.0 3.56e-01 89.9% 38.3%
4631364 7516.1.1.5 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › IspD 0.63 53.0 3.69e-01 94.2% 33.2%
4029247 247.1.1.29 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2, Anti-Pycsar_Apyc1 0.62 53.0 3.34e-01 100.0% 32.7%
3630518 2496.1.1.6 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › CRAL_TRIO_2 0.62 52.0 4.01e-01 98.6% 84.7%
4596140 2002.1.1.30 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 0.62 53.0 3.20e-01 100.0% 66.3%
2320951 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.62 51.0 3.63e-01 94.2% 78.7%
3277759 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.62 47.0 3.32e-01 85.5% 25.2%
4971361 7592.1.1.3 a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › DUF6293_N 0.61 47.0 4.00e-01 88.4% 49.2%
4096359 7516.1.1.5 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › IspD 0.61 50.0 3.48e-01 92.8% 31.8%
3981522 298.4.1.0 a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E 0.61 47.0 4.10e-01 85.5% 53.6%
4659212 7516.1.1.5 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › IspD 0.61 49.0 3.45e-01 91.3% 31.5%
4119794 2005.1.1.7 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1d 0.61 49.0 3.40e-01 92.8% 90.7%
4539830 7516.1.1.5 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › IspD 0.61 49.0 3.48e-01 92.8% 31.7%
5073860 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.61 51.0 4.16e-01 97.1% 77.7%
4978583 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.61 50.0 3.44e-01 91.3% 31.0%
3196251 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.60 51.0 4.02e-01 95.7% 49.3%
3249798 2003.1.5.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 0.60 50.0 3.51e-01 98.6% 29.8%
4945256 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.60 50.0 3.55e-01 97.1% 44.7%
5047918 7592.1.1.0 a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains 0.60 45.0 3.80e-01 92.8% 45.4%
3398173 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.60 50.0 3.25e-01 95.7% 26.3%
1513133 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.59 48.0 3.49e-01 94.2% 76.5%
5028069 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.59 47.0 3.35e-01 92.8% 33.1%
3964157 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.58 48.0 3.45e-01 95.7% 78.3%
4993477 2003.1.4.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › DS 0.58 39.0 3.15e-01 72.5% 33.1%
5070067 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.58 48.0 3.37e-01 95.7% 33.6%
5072515 300.1.1.0 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.58 49.0 3.82e-01 98.6% 93.3%
3947532 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.58 45.0 3.85e-01 89.9% 50.8%
3744246 2484.1.1.104 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_1 0.58 48.0 3.31e-01 97.1% 44.9%
3195505 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.57 48.0 3.55e-01 100.0% 86.7%
4020211 7590.1.1.0 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs 0.57 46.0 3.78e-01 95.7% 64.8%
3600635 3261.1.1.0 a+b two layers › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb 0.57 44.0 3.63e-01 84.1% 52.8%
3711262 3261.1.1.0 a+b two layers › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb › amino-terminal domain of OmpATb 0.56 44.0 4.07e-01 85.5% 71.1%
3810687 2005.1.1.43 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CHX17_2nd 0.56 46.0 3.59e-01 95.7% 83.5%
3510656 2485.1.1.71 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › SelP_N 0.56 45.0 3.57e-01 92.8% 44.4%
3959793 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.56 48.0 3.36e-01 98.6% 53.2%
3958063 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 45.0 4.20e-01 97.1% 73.7%
4097188 298.4.1.2 a+b two layers › FwdE/GAPDH domain-like › V-type ATPase subunit E › V-type ATPase subunit E › FliH 0.55 44.0 3.81e-01 88.4% 57.3%
3267443 2496.1.1.1 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › CRAL_TRIO 0.55 46.0 3.50e-01 100.0% 70.0%
None 0.55 48.0 2.91e-01 100.0% 34.7%
4942364 7516.1.1.1 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.55 45.0 3.11e-01 95.7% 67.4%
4464341 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 43.0 3.74e-01 92.8% 85.8%
4946141 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.55 46.0 3.37e-01 100.0% 94.4%
1522913 7523.1.1.15 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.55 41.0 3.79e-01 98.6% 61.7%
5076942 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.54 46.0 3.57e-01 95.7% 58.7%
4411262 3008.1.1.0 a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.54 40.0 3.99e-01 82.6% 79.5%
4546046 7542.1.2.0 a/b three-layered sandwiches › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain II 0.54 41.0 3.96e-01 87.0% 76.5%
4192832 7542.1.2.1 a/b three-layered sandwiches › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain II › Aconitase 0.54 42.0 4.00e-01 88.4% 76.5%
3307688 2006.1.1.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Acid_phosphat_B 0.54 44.0 3.19e-01 94.2% 91.3%
3911725 2007.9.1.1 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR 0.53 44.0 3.46e-01 98.6% 74.7%
4936753 7516.1.1.24 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transf_3 0.53 43.0 3.12e-01 94.2% 34.7%
3703121 7579.1.1.28 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S28 0.53 41.0 3.29e-01 92.8% 89.7%
3441606 207.1.1.79 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › F-box 0.52 44.0 2.77e-01 100.0% 94.3%
5029775 2484.1.1.38 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 0.52 42.0 3.57e-01 94.2% 80.8%
3327526 7579.1.1.6 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.52 45.0 3.23e-01 100.0% 57.2%
5064517 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.50 41.0 3.40e-01 94.2% 77.8%