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rifcsphigho2-12_scaffold_combined_curated_prodigal-single.1__X__X__00304
Bact-Virrifcsphigho2-12_scaffold_combined_curated_prodigal-single.1__X__X__00304
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-135
Domain cluster:
rep: OQ921342.1__WIT27079.1__X__00092__D2-126
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 48.0 | 4.04e-01 | 77.4% | 41.4% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 45.0 | 5.01e-01 | 91.0% | 78.7% |
| 2pmsC00 | 6.10.140.920 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 49.0 | 5.43e-01 | 71.4% | 91.7% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 45.0 | 5.43e-01 | 94.0% | 95.7% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.68 | 51.0 | 4.07e-01 | 77.4% | 75.9% |
| 2c0uA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 45.0 | 4.17e-01 | 75.2% | 53.8% |
| 2oexA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.67 | 49.0 | 4.80e-01 | 75.2% | 72.7% |
| 2pg0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 43.0 | 4.17e-01 | 77.4% | 58.4% |
| 3whjA00 | 6.10.140.1710 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 43.0 | 4.72e-01 | 94.7% | 79.3% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.66 | 44.0 | 4.68e-01 | 92.5% | 76.5% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 48.0 | 4.20e-01 | 75.2% | 81.4% |
| 8b6jF01 | 1.10.287.20 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain | 0.63 | 31.0 | 4.06e-01 | 72.9% | 89.6% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 46.0 | 4.33e-01 | 77.4% | 66.0% |
| 3r4iA02 | 6.10.140.960 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 20.0 | 2.99e-01 | 74.4% | 63.3% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.61 | 32.0 | 3.93e-01 | 72.9% | 80.0% |
| 2kseA00 | 1.20.5.1040 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Sensor protein qsec. | 0.59 | 33.0 | 4.25e-01 | 91.0% | 96.1% |
| 7d3uC01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 40.0 | 4.37e-01 | 88.0% | 86.0% |
| 3geeA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.58 | 40.0 | 3.77e-01 | 77.4% | 57.1% |
| 3vkgB03 | 1.20.58.1120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 | 0.57 | 43.0 | 4.08e-01 | 85.7% | 66.7% |
| 2o6yA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.56 | 50.0 | 3.78e-01 | 96.2% | 70.8% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.56 | 42.0 | 4.16e-01 | 96.2% | 72.4% |
| 1b8fA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.56 | 48.0 | 3.70e-01 | 100.0% | 40.6% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.54 | 43.0 | 4.06e-01 | 94.0% | 70.1% |
| 1lnwF01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 31.0 | 3.21e-01 | 72.2% | 60.5% |
| 2pfmA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.52 | 46.0 | 3.72e-01 | 97.0% | 73.8% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 47.0 | 3.89e-01 | 96.2% | 70.7% |
| 4a64C03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.51 | 34.0 | 3.84e-01 | 93.2% | 89.0% |
| 2ba0A03 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.51 | 32.0 | 3.76e-01 | 94.7% | 97.6% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3803978 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.76 | 51.0 | 5.10e-01 | 77.4% | 66.7% |
| 3441655 | 3567.1.1.88 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › PGG | 0.75 | 49.0 | 4.36e-01 | 78.2% | 47.6% |
| None | — | 0.74 | 50.0 | 3.43e-01 | 80.5% | 21.7% | |
| 3443624 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.72 | 51.0 | 4.34e-01 | 80.5% | 46.8% |
| 3593719 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.69 | 53.0 | 4.65e-01 | 78.2% | 61.6% |
| 3174776 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.69 | 51.0 | 4.17e-01 | 75.9% | 80.4% |
| 3669232 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 50.0 | 4.98e-01 | 76.7% | 76.4% |
| 5018039 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.68 | 49.0 | 5.26e-01 | 76.7% | 85.2% |
| 3702575 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.67 | 48.0 | 5.19e-01 | 72.9% | 90.4% |
| 3598773 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.67 | 51.0 | 4.23e-01 | 78.2% | 62.3% |
| 3606470 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.67 | 51.0 | 4.41e-01 | 78.2% | 70.3% |
| 3649819 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.66 | 49.0 | 5.08e-01 | 75.9% | 80.8% |
| 4650317 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.66 | 49.0 | 4.76e-01 | 76.7% | 75.9% |
| 3339348 | 606.1.1.12 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Rx_N | 0.66 | 50.0 | 5.06e-01 | 78.2% | 81.5% |
| 3385045 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 49.0 | 4.96e-01 | 77.4% | 83.1% |
| 4446432 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.64 | 48.0 | 3.92e-01 | 76.7% | 75.8% |
| 3948731 | 192.10.1.1 ↗ | alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › DksA_N | 0.64 | 47.0 | 4.99e-01 | 91.0% | 84.2% |
| 3208746 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.63 | 41.0 | 3.59e-01 | 80.5% | 41.9% |
| 3431118 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.62 | 43.0 | 4.72e-01 | 87.2% | 86.4% |
| 3582590 | 3291.1.1.9 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF2371 | 0.62 | 46.0 | 4.83e-01 | 76.7% | 85.0% |
| 3783794 | 192.15.1.77 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › OST3_OST6 | 0.62 | 50.0 | 5.17e-01 | 84.2% | 92.0% |
| 3596846 | 4992.1.1.0 ↗ | extended segments › RelB-like › RelB-like › RelB-like | 0.62 | 41.0 | 4.01e-01 | 75.2% | 61.4% |
| 3575264 | 604.12.1.61 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Clc-like | 0.60 | 43.0 | 4.66e-01 | 94.7% | 85.2% |
| 3827214 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.60 | 40.0 | 3.93e-01 | 92.5% | 62.8% |
| 3764098 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 44.0 | 3.99e-01 | 94.7% | 57.8% |
| 5053794 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.58 | 42.0 | 4.33e-01 | 76.7% | 77.7% |
| 3893414 | 1021.1.1.0 ↗ | a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases | 0.56 | 37.0 | 4.11e-01 | 75.9% | 83.8% |
| 3595074 | 180.1.1.0 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase | 0.55 | 47.0 | 4.29e-01 | 93.2% | 75.6% |
| 4343390 | 109.4.1.451 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Iml2-TPR_39 | 0.54 | 42.0 | 2.67e-01 | 98.5% | 16.1% |
| 3886245 | 3562.1.1.1 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Orai-1 | 0.54 | 49.0 | 4.14e-01 | 100.0% | 72.4% |
| 3624435 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 40.0 | 3.85e-01 | 94.0% | 69.0% |
| 3490709 | 102.1.3.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain | 0.52 | 45.0 | 4.45e-01 | 94.7% | 93.8% |
| 3580346 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.52 | 40.0 | 3.32e-01 | 94.7% | 46.0% |
| 3274839 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.52 | 48.0 | 3.74e-01 | 100.0% | 53.3% |
| 3553628 | 109.4.1.120 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Kinetochor_Ybp2 | 0.52 | 46.0 | 3.32e-01 | 97.7% | 36.3% |
| 3837979 | 3799.1.1.0 ↗ | alpha bundles › SabA N-terminal extracellular adhesion domain › SabA N-terminal extracellular adhesion domain › SabA N-terminal extracellular adhesion domain | 0.51 | 44.0 | 3.52e-01 | 92.5% | 93.5% |
| 4593130 | 601.7.1.40 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Cas13a_C | 0.51 | 39.0 | 2.90e-01 | 79.7% | 93.9% |
| 3911582 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.51 | 44.0 | 4.25e-01 | 92.5% | 86.7% |