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serine_proteinase_inhibitor_1

Euk-Vir

BeAn_58058_virus

serine_proteinase_inhibitor_1__YP_009329635__BeAn_58058_virus__67082

Identity

Accession:
YP_009329635 ↗
Protein ID:
serine_proteinase_inhibitor_1
Kingdom:
euk

Quality

86.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 15-98_207-271
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00079.26 best Serpin 41.7 1.20e-10 57.7% 22.2%
PF00079.26 Serpin 46.2 5.40e-12 45.6% 16.5%
D2 high residues 132-203
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00079.26 best Serpin 32.6 7.10e-08 98.6% 16.2%
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1lj5A02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.94 87.0 6.53e-01 100.0% 45.5%
4dy0B02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.94 86.0 6.92e-01 100.0% 54.7%
3zhaQ02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.89 76.0 6.11e-01 100.0% 50.4%
3f02B02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.88 80.0 7.04e-01 100.0% 70.0%
1i99I02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.84 73.0 6.10e-01 100.0% 57.3%
5c98B02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.81 76.0 6.08e-01 100.0% 58.9%
7vljA01 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.75 60.0 5.51e-01 100.0% 67.7%
2jmuA01 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.68 49.0 3.52e-01 77.8% 70.9%
2g2sA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.65 46.0 4.83e-01 81.9% 84.4%
6m9yA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.64 45.0 4.89e-01 81.9% 94.7%
6gp1A00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.63 44.0 4.61e-01 75.0% 81.5%
6ka3A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.62 47.0 3.81e-01 81.9% 49.0%
2nlkA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.62 42.0 2.88e-01 70.8% 29.2%
3akoC00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.60 49.0 3.95e-01 93.1% 69.8%
2qkdA03 2.20.25.420 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › ZPR1, zinc finger domain 0.58 39.0 4.54e-01 76.4% 100.0%
7arcC01 3.30.460.80 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › NADH:ubiquinone oxidoreductase Nqo5 subunit 0.57 41.0 3.31e-01 94.4% 40.0%
4pj2A00 2.40.128.460 Mainly Beta › Beta Barrel › Lipocalin › Periplasmic lysozyme inhibitor of I-type lysozyme 0.57 43.0 3.68e-01 81.9% 49.6%
5mu3B00 3.40.50.12050 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 41.0 3.18e-01 76.4% 60.7%
2kt4B01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.57 41.0 3.35e-01 77.8% 42.3%
1ah5A03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.57 40.0 3.76e-01 100.0% 61.6%
4dduA07 2.60.510.20 Mainly Beta › Sandwich › EV matrix protein fold › 0.56 42.0 3.69e-01 100.0% 54.2%
7ovuA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.56 48.0 3.61e-01 100.0% 45.6%
3u2sC00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.55 34.0 3.18e-01 94.4% 47.8%
6euaA01 3.90.215.10 Alpha Beta › Alpha-Beta Complex › Gamma Fibrinogen; Chain A, domain 1 › Gamma Fibrinogen, chain A, domain 1 0.54 38.0 3.12e-01 91.7% 38.1%
4i0kA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 38.0 3.50e-01 75.0% 55.8%
5hpfA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.54 41.0 3.08e-01 98.6% 33.1%
2giaA00 2.30.31.40 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › 0.54 41.0 3.36e-01 87.5% 69.5%
2g7uC02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.54 40.0 3.03e-01 98.6% 32.6%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.54 41.0 4.00e-01 100.0% 74.7%
1fu1A01 2.170.210.10 Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › DNA double-strand break repair and VJ recombination XRCC4, N-terminal 0.53 47.0 4.02e-01 100.0% 99.2%
2ia7A00 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 37.0 3.25e-01 73.6% 92.8%
7r97A02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.52 33.0 3.38e-01 100.0% 66.2%
3dmbA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.52 44.0 3.63e-01 100.0% 65.8%
3a58A01 2.30.29.90 Mainly Beta › Roll › PH-domain like › 0.52 41.0 3.17e-01 87.5% 60.9%
2rs7A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.52 37.0 3.69e-01 100.0% 73.0%
5tjjB02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.52 41.0 3.14e-01 87.5% 88.8%
3zqsA01 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.52 39.0 3.71e-01 81.9% 67.0%
1x67A01 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.52 44.0 3.69e-01 100.0% 72.2%
3r4kA02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.51 40.0 3.01e-01 100.0% 34.1%
4l8hB00 3.30.380.10 Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein 0.51 39.0 3.32e-01 83.3% 80.5%
3igrA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 45.0 3.39e-01 100.0% 57.4%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.51 36.0 3.61e-01 84.7% 72.7%
3vrdB03 3.90.760.10 Alpha Beta › Alpha-Beta Complex › Flavocytochrome C Sulfide Dehydrogenase; Chain A Domain 3 › Flavocytochrome c sulphide dehydrogenase, flavin-binding domain 0.51 36.0 3.58e-01 75.0% 90.5%
2o0yB02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.50 39.0 2.96e-01 100.0% 34.5%
1c9rA04 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.50 38.0 3.43e-01 84.7% 82.2%
2fsrA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.50 43.0 3.37e-01 100.0% 45.0%
2eenA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.50 41.0 3.28e-01 100.0% 62.7%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4458125 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.97 90.0 5.50e-01 100.0% 19.8%
154136 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.94 87.0 5.25e-01 100.0% 18.3%
3900687 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.94 87.0 5.25e-01 100.0% 18.4%
986348 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.94 86.0 5.32e-01 100.0% 19.8%
4067074 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.92 84.0 5.09e-01 100.0% 18.4%
3884984 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.69 51.0 4.23e-01 77.8% 48.8%
3265334 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.66 51.0 4.40e-01 81.9% 74.5%
4797813 271.1.1.1 beta barrels › GFP-like › GFP-like › GFP-like › GFP 0.64 45.0 4.89e-01 81.9% 94.7%
3815916 216.1.1.4 a+b two layers › UBC-like › UBC-like › UBC-like › RWD 0.63 49.0 3.95e-01 83.3% 66.4%
4927548 331.3.1.9 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › AHSA1 0.63 46.0 3.93e-01 77.8% 52.5%
3723442 216.1.1.4 a+b two layers › UBC-like › UBC-like › UBC-like › RWD 0.63 48.0 3.97e-01 81.9% 55.4%
4015374 11.8.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Osmotin-like › Osmotin-like 0.62 46.0 3.73e-01 80.6% 83.6%
3962822 331.3.1.2 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Ring_hydroxyl_A 0.62 51.0 4.09e-01 88.9% 71.9%
3417430 331.1.1.0 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.62 48.0 4.29e-01 86.1% 61.0%
4115704 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.61 41.0 4.08e-01 100.0% 66.7%
3966797 283.2.1.1 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › GPW_gp25 0.61 39.0 3.35e-01 98.6% 40.9%
3735671 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.59 40.0 3.59e-01 100.0% 51.0%
3924626 2484.1.1.4 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H 0.58 42.0 4.02e-01 98.6% 65.9%
3666722 11.10.1.5 beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like › MATH_2 0.57 44.0 3.55e-01 84.7% 75.2%
3723171 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 40.0 3.11e-01 95.8% 34.7%
4004011 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.57 40.0 3.52e-01 100.0% 49.1%
3352475 330.3.1.0 a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.57 45.0 4.45e-01 100.0% 81.3%
3998224 4272.1.1.1 a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa 0.57 41.0 3.22e-01 94.4% 37.2%
3085049 11.1.1.96 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › C1-set 0.56 38.0 3.21e-01 70.8% 89.9%
3173109 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.55 42.0 3.49e-01 100.0% 46.4%
4272864 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.55 45.0 3.82e-01 100.0% 53.3%
5023443 330.4.1.0 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.55 37.0 3.93e-01 100.0% 78.5%
3280054 331.3.1.11 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.55 39.0 3.21e-01 77.8% 69.3%
3706496 7026.1.1.0 beta meanders › N-terminal region of lipid transporter Vps13 › N-terminal region of lipid transporter Vps13 › N-terminal region of lipid transporter Vps13 0.55 38.0 2.65e-01 73.6% 67.0%
3594465 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.54 37.0 4.06e-01 72.2% 90.9%
3235699 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.54 38.0 3.31e-01 100.0% 47.0%
4012884 7525.1.1.0 a/b three-layered sandwiches › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like 0.54 39.0 2.94e-01 80.6% 98.1%
5080802 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.54 42.0 4.52e-01 95.8% 98.3%
4054729 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.54 40.0 3.97e-01 100.0% 76.0%
4216680 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.54 39.0 3.57e-01 100.0% 59.1%
4365325 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.54 39.0 3.69e-01 100.0% 64.7%
3472467 284.1.3.0 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.54 40.0 4.04e-01 84.7% 85.3%
222972 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.54 41.0 3.83e-01 100.0% 66.3%
3830643 2484.1.1.67 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.53 40.0 3.70e-01 97.2% 63.3%
3593683 2492.1.1.0 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like 0.53 37.0 2.55e-01 75.0% 45.4%
3631621 2484.1.1.24 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.53 40.0 3.10e-01 83.3% 92.6%
4935472 330.4.1.0 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.53 39.0 3.98e-01 100.0% 81.4%
4611568 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.53 39.0 3.91e-01 100.0% 77.3%
4965501 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.53 37.0 3.44e-01 100.0% 58.9%
3258455 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.52 40.0 3.49e-01 100.0% 54.1%
4967370 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.52 37.0 3.48e-01 100.0% 60.0%
4132764 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.52 38.0 3.64e-01 100.0% 65.9%
3404964 221.13.1.0 a+b two layers › beta-Grasp › Mitochondrial calcium uniporter N-terminal domain › Mitochondrial calcium uniporter N-terminal domain 0.52 41.0 3.66e-01 90.3% 94.8%
3211024 221.13.1.0 a+b two layers › beta-Grasp › Mitochondrial calcium uniporter N-terminal domain › Mitochondrial calcium uniporter N-terminal domain 0.52 38.0 3.45e-01 80.6% 90.5%
3938447 2484.1.1.4 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H 0.52 42.0 3.35e-01 94.4% 80.6%
3739683 220.1.1.20 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_TFIIH 0.52 39.0 3.40e-01 93.1% 52.7%
4029815 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.52 43.0 3.51e-01 88.9% 82.3%
4609498 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.52 36.0 3.52e-01 73.6% 71.2%
3827488 319.1.1.15 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › PF27746 0.52 39.0 3.43e-01 97.2% 53.6%
4135153 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.51 38.0 3.83e-01 100.0% 77.3%
5018871 213.1.1.25 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_3 0.51 44.0 3.48e-01 100.0% 61.9%
3194095 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.51 39.0 3.56e-01 100.0% 62.1%
3269121 220.1.1.20 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_TFIIH 0.51 38.0 3.33e-01 94.4% 52.7%
3680900 220.1.1.78 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_2 0.50 43.0 3.64e-01 94.4% 68.3%