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serine_threonine_protein_kinase

Euk-Vir

Marseillevirus_marseillevirus

serine_threonine_protein_kinase__YP_003407148__Marseillevirus_marseillevirus__694581

Identity

Accession:
YP_003407148 ↗
Protein ID:
serine_threonine_protein_kinase
Kingdom:
euk

Quality

85.5 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Marseilleviridae› Marseillevirus› Marseillevirus_marseillevirus

TaxID: 694581

Cluster

View cluster (72 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-64
PDB
Domain cluster: rep: serine_threonine_protein_kinase__YP_009507063__Tunisvirus_fontaine2__1421067__D4-64
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1blxA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.86 79.0 6.78e-01 100.0% 94.6%
6yllA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.85 77.0 6.92e-01 98.4% 100.0%
1yxsA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.82 73.0 6.39e-01 100.0% 91.3%
3nynB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.81 73.0 4.73e-01 100.0% 31.0%
2wtkC01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.81 72.0 6.35e-01 100.0% 88.8%
6ziwI01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.81 73.0 6.72e-01 100.0% 96.2%
2vd5B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.81 72.0 5.05e-01 100.0% 42.2%
3i6uA02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.77 70.0 6.16e-01 100.0% 86.2%
5hesA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.77 69.0 6.27e-01 100.0% 84.0%
2oo8X01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.76 59.0 5.97e-01 83.6% 93.3%
4fg9A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.75 67.0 6.15e-01 100.0% 86.1%
2z7rA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.75 67.0 6.02e-01 100.0% 83.3%
5cenA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.72 64.0 5.94e-01 100.0% 85.9%
3havA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.68 59.0 5.29e-01 100.0% 77.5%
4glkA00 3.10.129.130 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › 0.62 54.0 3.97e-01 100.0% 52.1%
1e7uA04 3.30.1010.10 Alpha Beta › 2-Layer Sandwich › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 0.60 49.0 3.82e-01 100.0% 57.0%
5lohB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.60 50.0 4.80e-01 100.0% 83.8%
1s28A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.59 50.0 4.03e-01 100.0% 56.2%
3tu3A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.58 47.0 4.00e-01 98.4% 58.8%
4gf3A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.57 47.0 3.93e-01 100.0% 56.1%
4oloB00 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.57 42.0 3.91e-01 83.6% 77.4%
2nr4A01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.54 43.0 3.53e-01 95.1% 82.7%
1dusA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 46.0 3.34e-01 100.0% 74.2%
1a5yA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.54 43.0 2.91e-01 93.4% 60.2%
7npaA02 3.30.70.3340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 45.0 4.06e-01 95.1% 69.4%
2hf2B02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.53 46.0 3.86e-01 100.0% 74.8%
4lq0A02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.52 40.0 3.16e-01 88.5% 45.6%
4dw8A02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.52 43.0 3.71e-01 98.4% 76.4%
3jz3B01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.52 42.0 3.25e-01 93.4% 69.6%
1nf2A02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.51 43.0 3.71e-01 100.0% 76.4%
2qmlA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 42.0 3.08e-01 98.4% 59.1%
7plsA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.50 42.0 3.76e-01 98.4% 95.7%
2cqpA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.50 36.0 3.23e-01 80.3% 66.3%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3894646 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.84 75.0 4.83e-01 98.4% 26.2%
2137571 206.1.1.74 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr 0.80 73.0 5.48e-01 100.0% 44.9%
3758771 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.80 71.0 4.41e-01 100.0% 22.9%
3675097 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.78 71.0 4.39e-01 100.0% 21.3%
3292650 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.77 69.0 4.30e-01 100.0% 22.2%
3723206 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.76 69.0 4.49e-01 100.0% 28.2%
3357283 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.76 68.0 4.17e-01 100.0% 18.9%
3446439 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.74 66.0 4.15e-01 100.0% 21.3%
3656665 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.74 66.0 4.11e-01 100.0% 20.0%
3652776 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.74 66.0 4.11e-01 100.0% 21.5%
5067728 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.72 63.0 4.24e-01 100.0% 28.7%
3962924 1.1.5.44 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › SecDF_P1_head 0.72 56.0 4.64e-01 85.2% 63.9%
5000427 4246.1.1.0 ↗ a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.68 59.0 3.71e-01 98.4% 35.7%
3232606 11.1.5.97 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › DUF7808 0.64 51.0 4.22e-01 86.9% 55.5%
4234613 206.1.1.9 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.64 50.0 3.58e-01 90.2% 38.5%
3703176 64.1.1.0 ↗ beta meanders › WW domain-like › WW domain › WW domain 0.64 36.0 4.12e-01 90.2% 75.0%
4648737 1.1.5.44 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › SecDF_P1_head 0.63 48.0 3.78e-01 85.2% 47.9%
3605879 64.1.1.0 ↗ beta meanders › WW domain-like › WW domain › WW domain 0.61 36.0 4.06e-01 95.1% 77.8%
3188677 306.3.1.2 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › Img2 0.60 47.0 4.36e-01 86.9% 67.5%
3254803 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 51.0 3.50e-01 100.0% 26.4%
4627664 601.23.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_III 0.58 50.0 3.16e-01 95.1% 21.8%
4626252 4271.1.1.3 ↗ alpha complex topology › PriB N-terminal domain-like › PriB N-terminal domain-like › PriB N-terminal domain-like › DNA_primase_lrg_N 0.58 49.0 3.36e-01 93.4% 27.7%
1316837 304.54.1.1 ↗ a+b two layers › Alpha-beta plaits › CcmK-like › CcmK-like › BMC 0.57 42.0 3.95e-01 83.6% 81.5%
3433847 206.1.1.14 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.57 45.0 3.02e-01 100.0% 39.4%
3586672 6050.1.1.0 ↗ a+b two layers › Phage tail assembly chaperone › Phage tail assembly chaperone › Phage tail assembly chaperone 0.56 42.0 3.62e-01 83.6% 89.5%
4957561 6050.1.1.0 ↗ a+b two layers › Phage tail assembly chaperone › Phage tail assembly chaperone › Phage tail assembly chaperone 0.56 42.0 3.62e-01 83.6% 97.1%
3485482 10.1.1.10 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › MAM 0.55 46.0 3.24e-01 93.4% 89.5%
1513169 6043.1.1.2 ↗ a+b two layers › yfeY-like › yfeY-like › yfeY-like › DUF4309 0.54 35.0 3.27e-01 100.0% 50.6%
4978474 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.54 40.0 3.20e-01 90.2% 37.8%
3482386 10.32.1.5 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Ephrin_lbd 0.53 42.0 3.15e-01 90.2% 85.9%
3479084 12.5.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related 0.53 45.0 3.43e-01 96.7% 72.7%
5060878 7523.1.1.0 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.53 33.0 2.85e-01 91.8% 33.9%
3738420 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.53 42.0 3.44e-01 90.2% 88.3%
5023543 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.52 39.0 3.37e-01 93.4% 50.0%
4997179 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.51 40.0 3.57e-01 90.2% 61.7%
3112292 66.1.1.0 ↗ beta sandwiches › ISP domain › ISP domain › ISP domain 0.51 42.0 4.04e-01 100.0% 98.7%
5039290 4.6.1.0 ↗ beta barrels › SH3 › PRC-barrel domain › PRC-barrel domain 0.50 40.0 3.82e-01 90.2% 76.0%
1621735 66.1.1.0 ↗ beta sandwiches › ISP domain › ISP domain › ISP domain 0.50 42.0 3.86e-01 100.0% 92.9%
D2 high residues 68-193
PDB
Domain cluster: rep: MG450654.1__ATW62846.1__SCBWM1_gp162__00163__D192-294
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF00069.32 best Pkinase 90.0 2.50e-25 99.2% 45.8%
PF07714.24 PK_Tyr_Ser-Thr 46.0 6.20e-12 92.9% 43.8%
PF03109.23 ABC1 26.8 3.90e-06 46.0% 17.5%