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serpin_family_protein
Euk-VirTurkeypox_virus
serpin_family_protein__YP_009177040__Turkeypox_virus__336486
Identity
- Accession:
- YP_009177040 ↗
- Protein ID:
- serpin_family_protein
- Kingdom:
- euk
Quality
75.9
mean pLDDT
Cluster
View cluster (68 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-145_227-292
Domain cluster:
rep: Serpin_1__YP_009408115__Eptesipox_virus__1329402__D1-137_237-300
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2h4pA01 | 3.30.497.10 | Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 | 0.76 | 69.0 | 6.52e-01 | 94.8% | 96.0% |
| 1mtpA01 | 3.30.497.10 | Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 | 0.74 | 67.0 | 6.57e-01 | 94.8% | 98.2% |
| 3ndaA01 | 3.30.497.10 | Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 | 0.74 | 67.0 | 6.37e-01 | 94.8% | 96.7% |
| 5i8fA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.53 | 25.0 | 2.82e-01 | 95.3% | 55.5% |
| 2le1A00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.52 | 23.0 | 2.68e-01 | 94.3% | 55.0% |
| 3tfzB00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.52 | 24.0 | 2.67e-01 | 94.8% | 52.7% |
| 4xrtA02 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.51 | 23.0 | 2.66e-01 | 94.8% | 54.4% |
| 1z94B00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.51 | 23.0 | 2.78e-01 | 94.3% | 62.2% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 154136 | 4059.1.1.0 ↗ | a+b complex topology › Serpins › Serpins › Serpins | 0.76 | 72.0 | 5.77e-01 | 100.0% | 96.1% |
| 4783841 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.73 | 64.0 | 5.51e-01 | 91.0% | 100.0% |
| 2709787 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.72 | 69.0 | 5.62e-01 | 100.0% | 96.7% |
| 3957979 | 4059.1.1.0 ↗ | a+b complex topology › Serpins › Serpins › Serpins | 0.72 | 65.0 | 5.63e-01 | 95.3% | 95.2% |
| 3937095 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.71 | 67.0 | 5.47e-01 | 100.0% | 98.4% |
| 5051779 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.55 | 21.0 | 2.83e-01 | 93.8% | 62.7% |
| 5040587 | 331.3.1.11 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 | 0.54 | 23.0 | 2.73e-01 | 95.3% | 53.5% |
| 2634554 | 331.3.1.1 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Bet_v_1 | 0.52 | 25.0 | 2.81e-01 | 95.3% | 55.8% |
| 3953672 | 331.3.1.5 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc | 0.52 | 23.0 | 2.71e-01 | 94.8% | 55.5% |
| 3479192 | 220.1.1.18 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PTB | 0.52 | 32.0 | 3.65e-01 | 91.5% | 81.9% |
| 5038407 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.52 | 23.0 | 2.75e-01 | 94.8% | 58.0% |
| 4289286 | 331.3.1.5 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc | 0.51 | 23.0 | 2.75e-01 | 94.8% | 58.0% |
| 3962603 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.50 | 23.0 | 3.10e-01 | 89.6% | 80.9% |
D2
medium
residues 146-226_293-317
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1wz9A02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.83 | 77.0 | 6.91e-01 | 100.0% | 98.6% |
| 4zk3A02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.80 | 73.0 | 6.86e-01 | 99.1% | 100.0% |
| 3zhaQ02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.78 | 72.0 | 6.67e-01 | 100.0% | 96.9% |
| 3ndaA02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.77 | 70.0 | 6.51e-01 | 100.0% | 98.5% |
| 7vljA01 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.76 | 56.0 | 5.94e-01 | 76.4% | 98.9% |
| 3pzfA01 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.75 | 68.0 | 5.72e-01 | 100.0% | 80.9% |
| 1jrrA01 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.74 | 68.0 | 6.46e-01 | 99.1% | 100.0% |
| 2v95A02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.73 | 67.0 | 6.24e-01 | 100.0% | 98.4% |
| 3stoA02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.73 | 66.0 | 5.94e-01 | 100.0% | 97.9% |
| 1lj5A02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.73 | 66.0 | 5.82e-01 | 100.0% | 96.8% |
| 3ozqA01 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.72 | 66.0 | 5.64e-01 | 100.0% | 77.6% |
| 1x7dB01 | 3.30.1780.10 | Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 | 0.64 | 46.0 | 3.91e-01 | 100.0% | 46.7% |
| 1y8cA02 | 2.20.25.110 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases | 0.61 | 31.0 | 3.86e-01 | 78.3% | 83.3% |
| 1omoA01 | 3.30.1780.10 | Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 | 0.60 | 43.0 | 3.82e-01 | 99.1% | 53.0% |
| 4bd4A00 | 2.60.40.200 | Mainly Beta › Sandwich › Immunoglobulin-like › Superoxide dismutase, copper/zinc binding domain | 0.58 | 40.0 | 3.97e-01 | 78.3% | 67.9% |
| 1wzlA04 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.54 | 40.0 | 4.53e-01 | 78.3% | 100.0% |
| 2xn2A03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.53 | 40.0 | 4.25e-01 | 81.1% | 100.0% |
| 2yfoA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.52 | 40.0 | 4.21e-01 | 81.1% | 100.0% |
| 2p4bB02 | 3.30.200.100 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › MucB/RseB, C-terminal domain | 0.52 | 38.0 | 3.98e-01 | 100.0% | 83.7% |
| 1srqA01 | 3.30.1120.160 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.52 | 40.0 | 3.66e-01 | 82.1% | 78.3% |
| 3a21A02 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.51 | 41.0 | 4.36e-01 | 87.7% | 100.0% |
| 1ulvA01 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.50 | 47.0 | 3.41e-01 | 100.0% | 60.3% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 279848 | 4059.1.1.0 ↗ | a+b complex topology › Serpins › Serpins › Serpins | 0.82 | 77.0 | 5.13e-01 | 100.0% | 53.9% |
| 3551728 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.82 | 77.0 | 5.11e-01 | 100.0% | 54.4% |
| 3843221 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.81 | 75.0 | 5.00e-01 | 100.0% | 52.2% |
| 2998442 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.80 | 74.0 | 5.00e-01 | 100.0% | 51.2% |
| 4262036 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.80 | 74.0 | 4.97e-01 | 100.0% | 51.2% |
| 358183 | 4059.1.1.0 ↗ | a+b complex topology › Serpins › Serpins › Serpins | 0.80 | 73.0 | 4.95e-01 | 100.0% | 55.1% |
| 3862912 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.80 | 73.0 | 4.90e-01 | 100.0% | 53.2% |
| 3918321 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.79 | 74.0 | 4.88e-01 | 100.0% | 50.9% |
| 3912871 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.79 | 73.0 | 4.87e-01 | 100.0% | 52.0% |
| 154755 | 4059.1.1.0 ↗ | a+b complex topology › Serpins › Serpins › Serpins | 0.78 | 72.0 | 4.85e-01 | 100.0% | 52.8% |
| 3395892 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.78 | 72.0 | 4.79e-01 | 100.0% | 51.9% |
| 4199509 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.77 | 72.0 | 4.87e-01 | 100.0% | 52.0% |
| 141145 | 4059.1.1.0 ↗ | a+b complex topology › Serpins › Serpins › Serpins | 0.77 | 71.0 | 4.76e-01 | 100.0% | 52.9% |
| 7646 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.77 | 71.0 | 4.76e-01 | 100.0% | 53.7% |
| 86481 | 4059.1.1.0 ↗ | a+b complex topology › Serpins › Serpins › Serpins | 0.77 | 71.0 | 4.75e-01 | 100.0% | 53.7% |
| 4955122 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.77 | 71.0 | 4.80e-01 | 100.0% | 55.1% |
| 3770064 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.76 | 70.0 | 4.70e-01 | 100.0% | 52.8% |
| 3630669 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.76 | 70.0 | 4.60e-01 | 100.0% | 54.0% |
| 3395896 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.76 | 69.0 | 4.68e-01 | 100.0% | 53.6% |
| 4058628 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.75 | 68.0 | 4.60e-01 | 100.0% | 53.8% |
| 3388801 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.74 | 67.0 | 4.55e-01 | 100.0% | 53.9% |
| 1289420 | 4059.1.1.0 ↗ | a+b complex topology › Serpins › Serpins › Serpins | 0.73 | 67.0 | 4.55e-01 | 100.0% | 52.3% |
| 3403800 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.73 | 66.0 | 4.49e-01 | 100.0% | 53.0% |
| 3404796 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.72 | 66.0 | 4.50e-01 | 100.0% | 54.6% |
| 4539644 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.72 | 65.0 | 4.50e-01 | 100.0% | 55.2% |
| 3389012 | 4059.1.1.1 ↗ | a+b complex topology › Serpins › Serpins › Serpins › Serpin | 0.71 | 65.0 | 4.40e-01 | 100.0% | 53.4% |
| 3414586 | 11.1.1.824 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Chitin_bind_4 | 0.66 | 37.0 | 4.00e-01 | 87.7% | 63.4% |
| 4969785 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.66 | 35.0 | 2.74e-01 | 90.6% | 25.6% |
| 4957722 | 71.1.1.0 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB | 0.65 | 41.0 | 3.72e-01 | 93.4% | 48.6% |
| 3270645 | 5.1.3.25 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Mcl1_mid | 0.62 | 40.0 | 2.82e-01 | 94.3% | 21.2% |
| 3599877 | 304.25.1.0 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain | 0.58 | 43.0 | 3.40e-01 | 94.3% | 38.3% |
| 3551012 | 3257.1.1.1 ↗ | a+b complex topology › Phosphoinositide phosphatase SAC1 N-terminal domain › Phosphoinositide phosphatase SAC1 N-terminal domain › Phosphoinositide phosphatase SAC1 N-terminal domain › Syja_N | 0.58 | 40.0 | 3.11e-01 | 70.8% | 84.3% |
| 1291143 | 9.1.1.17 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › MoaF | 0.56 | 45.0 | 3.95e-01 | 99.1% | 59.5% |
| 4490072 | 12.1.1.3 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Alpha-amylase_C | 0.56 | 46.0 | 4.62e-01 | 88.7% | 100.0% |
| 3959682 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.56 | 35.0 | 4.07e-01 | 74.5% | 89.3% |
| 4671861 | 11.1.1.14 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 | 0.54 | 35.0 | 3.61e-01 | 70.8% | 70.0% |
| 3512529 | 216.1.1.2 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › Autophagy_act_C | 0.53 | 43.0 | 3.76e-01 | 85.8% | 59.4% |
| 3290942 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 40.0 | 4.06e-01 | 88.7% | 79.0% |
| 4316811 | 12.1.1.27 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Glyco_hydro_36C | 0.53 | 40.0 | 4.27e-01 | 80.2% | 100.0% |
| 4426077 | 241.1.1.2 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › Autophagy_act_C | 0.53 | 45.0 | 3.92e-01 | 90.6% | 66.5% |
| 5083438 | 267.1.1.0 ↗ | a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain | 0.52 | 45.0 | 3.87e-01 | 94.3% | 65.5% |
| 3273331 | 2.9.1.1 ↗ | beta barrels › OB-fold › RNB domain-like › RNB domain-like › RNB | 0.52 | 44.0 | 2.95e-01 | 90.6% | 80.8% |
| 4269845 | 11.1.1.14 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 | 0.51 | 35.0 | 3.54e-01 | 70.8% | 70.9% |
| 4545659 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.51 | 34.0 | 3.93e-01 | 85.8% | 94.7% |
| 4959619 | 267.1.1.3 ↗ | a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase | 0.51 | 44.0 | 3.78e-01 | 94.3% | 60.0% |
| 3672562 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 42.0 | 2.49e-01 | 90.6% | 12.0% |
| 3534480 | 11.1.1.232 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › SKICH | 0.51 | 35.0 | 3.54e-01 | 73.6% | 71.4% |
| 3594086 | 267.1.1.0 ↗ | a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain | 0.51 | 44.0 | 3.28e-01 | 94.3% | 55.0% |
| 5012403 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.50 | 35.0 | 3.05e-01 | 71.7% | 57.0% |
| 3738735 | 2.9.1.1 ↗ | beta barrels › OB-fold › RNB domain-like › RNB domain-like › RNB | 0.50 | 43.0 | 2.86e-01 | 90.6% | 27.0% |