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single-stranded_DNA-binding_protein

Euk-Vir

Human_betaherpesvirus_7

single-stranded_DNA-binding_protein__YP_073781__Human_betaherpesvirus_7__10372

Identity

Accession:: YP_073781 ↗
Protein ID:: single-stranded_DNA-binding_protein
Kingdom:: euk

Quality

77.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_7

TaxID: 10372

Cluster

View cluster (33 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1004-1092

PDB

Domain cluster: rep: major_DNA_binding_protein__NP_050222__Human_betaherpesvirus_6B__32604__D1005-1084

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	64.4	5.00e-18	100.0%	7.8%

D2 medium residues 1-14_217-261_298-320_624-751

PDB

Domain cluster: representative

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	165.5	1.50e-48	71.9%	13.0%
PF00747.23	Viral_DNA_bp	44.3	5.70e-12	23.3%	4.1%

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1mn8D00	1.10.150.180	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Gamma-retroviral matrix domain	0.54	21.0	3.00e-01	76.2%	73.2%
1fouA01	1.10.246.30	Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 ›	0.53	18.0	3.05e-01	78.1%	85.1%
4d6wB02	6.10.140.740	Special › Helix non-globular › Helix Hairpins ›	0.53	20.0	2.92e-01	79.0%	75.0%

D3 medium residues 15-216

PDB

Domain cluster: rep: major_DNA_binding_protein__NP_042934__Human_betaherpesvirus_6A__32603__D1-185

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	220.5	3.60e-65	100.0%	18.7%

D4 medium residues 262-297_366-414

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	26.3	1.60e-06	54.1%	3.6%

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1nbwA05	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.65	23.0	3.05e-01	91.8%	53.3%
5h80B03	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.57	50.0	3.65e-01	100.0%	58.6%
3kmuA02	1.10.510.10	Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1	0.51	42.0	3.30e-01	89.4%	67.0%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4199578	314.1.1.9 ↗	a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_His	0.53	41.0	2.80e-01	85.9%	35.9%

D5 medium residues 415-499_874-905

PDB

Domain cluster: rep: major_DNA_binding_protein__NP_050222__Human_betaherpesvirus_6B__32604__D414-501

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	102.8	1.30e-29	73.5%	7.5%

D6 medium residues 500-520_856-873_906-963_979-1001

PDB

D7 medium residues 539-623_810-829_841-855

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	68.3	3.20e-19	71.7%	8.0%

CATH (13)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2rp4A00	6.10.280.60	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain	0.64	29.0	3.74e-01	79.2%	73.2%
3n2oA03	1.20.58.930	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	40.0	4.46e-01	85.8%	91.7%
4abnA01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.56	38.0	2.91e-01	99.2%	29.4%
4oydB00	1.10.132.20	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor	0.56	44.0	4.46e-01	91.7%	83.8%
2v6yA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.56	30.0	3.72e-01	95.0%	84.0%
4q5nA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.55	41.0	4.31e-01	100.0%	83.9%
1jogA00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.52	45.0	4.37e-01	93.3%	92.6%
1w99A01	1.20.190.10	Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain	0.52	46.0	4.10e-01	100.0%	68.2%
2ra1A01	1.20.58.790	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.51	35.0	3.87e-01	91.7%	86.7%
3swhA01	1.10.357.50	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 ›	0.51	46.0	4.17e-01	100.0%	77.0%
4xpwA00	1.20.120.50	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like	0.50	42.0	4.11e-01	96.7%	82.4%
5nl6A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.50	33.0	3.50e-01	95.0%	75.0%
6vmsR00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.50	45.0	3.41e-01	97.5%	47.5%

ECOD (14)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4030256	603.2.1.0 ↗	alpha bundles › STAT-like › STAT › STAT	0.65	38.0	4.20e-01	95.0%	71.6%
3706812	603.1.1.17 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE	0.56	46.0	3.50e-01	87.5%	79.3%
3173547	603.1.1.17 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE	0.54	49.0	3.92e-01	99.2%	97.0%
4979034	601.1.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin	0.54	49.0	4.85e-01	100.0%	95.2%
3927597	604.3.1.0 ↗	alpha bundles › Spectrin repeat-like › BAG domain › BAG domain	0.54	39.0	3.92e-01	74.2%	89.2%
3682864	192.29.1.101 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N	0.54	44.0	4.33e-01	93.3%	81.5%
3543893	604.1.1.1 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin	0.52	38.0	3.84e-01	94.2%	75.0%
3579213	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.52	36.0	3.81e-01	95.0%	78.2%
3719434	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.52	39.0	3.91e-01	95.0%	76.0%
3795092	622.4.1.0 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related	0.52	38.0	3.66e-01	75.8%	85.2%
3190165	601.1.1.81 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CcsR_C	0.52	47.0	3.68e-01	100.0%	81.2%
3740106	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.51	35.0	3.59e-01	93.3%	72.2%
4138504	310.2.1.1 ↗	a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF	0.51	44.0	3.78e-01	92.5%	88.6%
3934845	5001.1.1.66 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg	0.50	43.0	3.30e-01	94.2%	80.0%