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single-stranded_DNA-binding_protein
Euk-VirGallid_alphaherpesvirus_1
single-stranded_DNA-binding_protein__YP_182358__Gallid_alphaherpesvirus_1__10386
Identity
- Accession:
- YP_182358 ↗
- Protein ID:
- single-stranded_DNA-binding_protein
- Kingdom:
- euk
Quality
71.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Iltovirus›
Gallid_alphaherpesvirus_1
TaxID: 10386
Cluster
View cluster (33 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 872-948
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 31.9 | 3.10e-08 | 100.0% | 7.1% |
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1urjA03 | 1.10.150.560 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.88 | 83.0 | 8.12e-01 | 100.0% | 93.9% |
| 2x3mA00 | 1.25.40.670 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.73 | 52.0 | 4.05e-01 | 75.3% | 36.7% |
| 1dqeA00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.64 | 52.0 | 4.33e-01 | 89.6% | 88.3% |
| 1qdmA03 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.62 | 47.0 | 4.79e-01 | 84.4% | 83.1% |
| 4jaqA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.61 | 50.0 | 4.11e-01 | 100.0% | 49.0% |
| 4ivnA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.60 | 42.0 | 4.27e-01 | 74.0% | 81.6% |
| 4fcyA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.59 | 45.0 | 4.48e-01 | 80.5% | 80.8% |
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 37.0 | 4.18e-01 | 75.3% | 89.3% |
| 2qw6D00 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.58 | 46.0 | 4.53e-01 | 100.0% | 81.4% |
| 3s4lA00 | 1.10.3210.30 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › | 0.56 | 45.0 | 3.45e-01 | 92.2% | 66.5% |
| 2yhsA01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.56 | 44.0 | 4.19e-01 | 97.4% | 72.2% |
| 2o3fA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 41.0 | 4.06e-01 | 80.5% | 79.3% |
| 1v9mA01 | 1.10.132.50 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › ATP synthase (C/AC39) subunit, domain 3 | 0.55 | 40.0 | 3.55e-01 | 77.9% | 83.5% |
| 3b0pA02 | 1.20.120.1460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 42.0 | 4.28e-01 | 89.6% | 89.3% |
| 3r72A00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.53 | 45.0 | 3.94e-01 | 98.7% | 91.8% |
| 3ckyA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.52 | 46.0 | 3.86e-01 | 100.0% | 85.1% |
| 2nq2A00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.52 | 40.0 | 2.77e-01 | 88.3% | 30.5% |
| 2cvzA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 45.0 | 3.81e-01 | 100.0% | 88.6% |
| 2gf2A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 45.0 | 3.79e-01 | 100.0% | 92.5% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3055 | 102.6.1.1 ↗ | alpha arrays › HhH/H2TH › C-terminal domain in viral ssDNA binding protein › C-terminal domain in viral ssDNA binding protein › Viral_DNA_bp | 0.88 | 83.0 | 8.12e-01 | 100.0% | 93.9% |
| 1309095 | 102.6.1.1 ↗ | alpha arrays › HhH/H2TH › C-terminal domain in viral ssDNA binding protein › C-terminal domain in viral ssDNA binding protein › Viral_DNA_bp | 0.88 | 83.0 | 7.24e-01 | 100.0% | 70.6% |
| 3016251 | 532.2.1.1 ↗ | alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › HrpJ | 0.66 | 46.0 | 4.58e-01 | 75.3% | 69.6% |
| 3907073 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.58 | 42.0 | 4.68e-01 | 76.6% | 100.0% |
| 3277942 | 191.1.1.33 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_31 | 0.58 | 51.0 | 4.41e-01 | 100.0% | 79.0% |
| 4529419 | 101.1.1.11 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_6 | 0.58 | 41.0 | 4.19e-01 | 76.6% | 82.7% |
| 3171365 | 822.1.1.1 ↗ | a+b two layers › GYF/BRK domain-like › GYF domain › GYF domain › GYF | 0.57 | 43.0 | 3.43e-01 | 80.5% | 81.9% |
| 5001603 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.57 | 45.0 | 4.32e-01 | 89.6% | 93.3% |
| 3984938 | 101.1.6.0 ↗ | alpha arrays › HTH › HTH › TrpR | 0.54 | 45.0 | 4.49e-01 | 98.7% | 97.5% |
| 149157 | 108.2.1.1 ↗ | alpha arrays › EF-hand › Insect pheromone/odorant-binding proteins › Insect pheromone/odorant-binding proteins › PBP_GOBP | 0.53 | 45.0 | 3.94e-01 | 98.7% | 91.8% |
| 3236297 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.52 | 39.0 | 3.74e-01 | 83.1% | 81.1% |
D2
medium
residues 18-107_156-239_270-302_726-765
Domain cluster:
rep: ORF6__YP_001129352__Human_gammaherpesvirus_8__37296__D13-252_683-721
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 83.0 | 1.20e-23 | 37.2% | 7.3% |
| PF00747.23 | Viral_DNA_bp | 81.2 | 4.10e-23 | 34.8% | 7.1% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3p96A02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.52 | 20.0 | 3.35e-01 | 91.1% | 100.0% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7679 | 4174.1.1.1 ↗ | a+b complex topology › N-terminal domain in viral ssDNA binding protein › N-terminal domain in viral ssDNA binding protein › N-terminal domain in viral ssDNA binding protein › Viral_DNA_bp | 0.93 | 75.0 | 7.19e-01 | 81.4% | 98.9% |
| 3552442 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 17.0 | 2.50e-01 | 81.0% | 58.3% |
D3
medium
residues 108-155_240-269_390-400_417-473
Domain cluster:
rep: single-stranded_DNA-binding_protein__NP_073323__Meleagrid_alphaherpesvirus_1__37108__D110-131_237-282_449-492
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 51.3 | 4.40e-14 | 41.1% | 5.0% |
| PF00747.23 | Viral_DNA_bp | 32.0 | 3.10e-08 | 34.2% | 4.1% |
D4
medium
residues 474-540
D5
medium
residues 541-559_646-664_766-823
D6
medium
residues 560-645
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 55.5 | 2.40e-15 | 100.0% | 7.9% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 47.0 | 5.55e-01 | 97.7% | 100.0% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.71 | 45.0 | 4.50e-01 | 84.9% | 62.5% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.69 | 44.0 | 4.37e-01 | 82.6% | 61.1% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 45.0 | 4.60e-01 | 76.7% | 73.8% |
| 1ciiA02 | 3.30.305.10 | Alpha Beta › 2-Layer Sandwich › Colicin Ia; domain 2 › Colicin Ia; domain 2 | 0.65 | 42.0 | 3.95e-01 | 73.3% | 55.4% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 50.0 | 5.35e-01 | 89.5% | 98.6% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.63 | 48.0 | 4.59e-01 | 100.0% | 69.3% |
| 3spcA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 51.0 | 4.50e-01 | 90.7% | 87.4% |
| 5ljmA00 | 1.20.58.2190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 48.0 | 3.64e-01 | 84.9% | 53.2% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.60 | 40.0 | 4.07e-01 | 80.2% | 69.4% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.60 | 50.0 | 4.57e-01 | 91.9% | 99.1% |
| 7b00A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.59 | 47.0 | 2.93e-01 | 84.9% | 49.7% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.59 | 45.0 | 4.09e-01 | 88.4% | 60.3% |
| 1gaxA05 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.59 | 43.0 | 4.58e-01 | 88.4% | 89.0% |
| 3ipiA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.57 | 51.0 | 3.60e-01 | 100.0% | 77.6% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.56 | 43.0 | 4.41e-01 | 88.4% | 87.8% |
| 2etjA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.55 | 40.0 | 3.04e-01 | 75.6% | 56.7% |
| 4q5rA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 48.0 | 4.46e-01 | 97.7% | 91.1% |
| 5zyrA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 49.0 | 4.03e-01 | 97.7% | 88.7% |
| 2rd9B01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.55 | 47.0 | 3.84e-01 | 100.0% | 74.3% |
| 3purA03 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 39.0 | 3.63e-01 | 91.9% | 59.1% |
| 2yqrA01 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.53 | 48.0 | 4.57e-01 | 100.0% | 88.3% |
| 1ignA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.52 | 34.0 | 3.41e-01 | 93.0% | 62.4% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3844936 | 101.1.1.273 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › PF26094 | 0.69 | 36.0 | 3.87e-01 | 82.6% | 58.7% |
| 4217794 | 5086.1.1.94 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD | 0.68 | 53.0 | 4.62e-01 | 82.6% | 98.4% |
| 3441963 | 605.1.1.222 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF4220 | 0.65 | 54.0 | 4.87e-01 | 89.5% | 93.0% |
| 4876717 | 4070.1.1.1 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M41 | 0.64 | 56.0 | 4.23e-01 | 100.0% | 70.7% |
| 3862747 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.63 | 47.0 | 4.80e-01 | 88.4% | 81.2% |
| 3544534 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 45.0 | 4.62e-01 | 81.4% | 80.0% |
| 4020856 | 650.1.1.0 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain | 0.62 | 48.0 | 4.13e-01 | 82.6% | 64.4% |
| 3927597 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.62 | 50.0 | 4.53e-01 | 90.7% | 64.2% |
| 3646270 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.61 | 50.0 | 5.27e-01 | 91.9% | 100.0% |
| 3731115 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 50.0 | 4.18e-01 | 95.3% | 86.9% |
| 3730401 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.60 | 48.0 | 3.93e-01 | 88.4% | 76.2% |
| 3256828 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.59 | 41.0 | 3.73e-01 | 97.7% | 55.5% |
| 4585740 | 101.11.1.0 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0.57 | 46.0 | 4.53e-01 | 84.9% | 84.4% |
| 3229806 | 6157.1.1.1 ↗ | alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP | 0.57 | 51.0 | 4.65e-01 | 100.0% | 75.7% |
| 3257573 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.56 | 41.0 | 3.43e-01 | 88.4% | 40.6% |
| 4880296 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 42.0 | 4.22e-01 | 83.7% | 86.2% |
| 5037841 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.53 | 46.0 | 4.27e-01 | 100.0% | 89.6% |
| 4344487 | 375.1.1.179 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha | 0.51 | 41.0 | 3.39e-01 | 88.4% | 46.7% |
| 4221024 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 41.0 | 3.17e-01 | 89.5% | 38.0% |
| 3494678 | 220.1.1.60 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › ECT2_PH | 0.50 | 43.0 | 3.20e-01 | 96.5% | 87.7% |