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single-stranded_DNA-binding_protein
Euk-VirHuman_gammaherpesvirus_4
single-stranded_DNA-binding_protein__YP_401717__Human_gammaherpesvirus_4__10376
Identity
- Accession:
- YP_401717 ↗
- Protein ID:
- single-stranded_DNA-binding_protein
- Kingdom:
- euk
Quality
73.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Lymphocryptovirus›
human_gammaherpesvirus_4
TaxID: 10376
Cluster
View cluster (33 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 991-1073
Domain cluster:
rep: JM5__YP_238308__Macaca_fuscata_rhadinovirus__272551__D1010-1077
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 69.8 | 1.20e-19 | 100.0% | 7.3% |
D2
medium
residues 11-106_131-242_676-717
Domain cluster:
rep: ORF6__YP_001129352__Human_gammaherpesvirus_8__37296__D13-252_683-721
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 120.0 | 8.20e-35 | 46.4% | 11.5% |
| PF00747.23 | Viral_DNA_bp | 112.1 | 1.90e-32 | 40.0% | 8.6% |
D3
medium
residues 107-130_243-273_315-392_405-430_453-486_612-624
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 150.9 | 3.70e-44 | 72.8% | 15.7% |
D4
medium
residues 274-314_625-675
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 70.9 | 5.20e-20 | 56.5% | 4.5% |
| PF00747.23 | Viral_DNA_bp | 37.9 | 4.80e-10 | 45.6% | 3.6% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3v9rA00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.57 | 32.0 | 3.36e-01 | 88.0% | 58.0% |
| 7eq1R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 44.0 | 3.14e-01 | 88.0% | 36.8% |
| 1wgwA00 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.53 | 36.0 | 3.57e-01 | 94.6% | 65.7% |
| 3mekA03 | 1.10.220.160 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › | 0.51 | 29.0 | 3.02e-01 | 79.3% | 58.1% |
| 3lqhA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.51 | 35.0 | 3.41e-01 | 100.0% | 62.3% |
| 2hzdA00 | 6.10.20.40 | Special › Helix non-globular › Arc Repressor Mutant, subunit A › TEA/ATTS domain | 0.50 | 28.0 | 2.93e-01 | 85.9% | 59.8% |
D5
medium
residues 487-506_588-611_718-745_845-944_966-982
D6
medium
residues 524-587
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 51.8 | 3.20e-14 | 100.0% | 6.1% |
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 55.0 | 5.70e-01 | 98.4% | 93.1% |
| 5jazA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.70 | 50.0 | 4.44e-01 | 96.9% | 52.7% |
| 2ce7B03 | 1.20.58.760 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Peptidase M41 | 0.68 | 61.0 | 4.48e-01 | 100.0% | 72.0% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 59.0 | 5.47e-01 | 98.4% | 78.5% |
| 2b7mA00 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.67 | 59.0 | 3.47e-01 | 100.0% | 13.3% |
| 2vqrA01 | 3.40.720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A | 0.66 | 58.0 | 3.48e-01 | 100.0% | 66.2% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.64 | 50.0 | 4.08e-01 | 85.9% | 48.8% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 55.0 | 4.16e-01 | 98.4% | 56.1% |
| 6lo8F01 | 1.10.287.810 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains | 0.63 | 49.0 | 4.87e-01 | 95.3% | 81.2% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 46.0 | 5.07e-01 | 82.8% | 100.0% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.62 | 50.0 | 3.89e-01 | 92.2% | 67.8% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.62 | 53.0 | 4.61e-01 | 98.4% | 96.1% |
| 1wu3I00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.62 | 51.0 | 3.88e-01 | 95.3% | 71.4% |
| 3ns4A00 | 1.10.357.110 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Vacuolar protein sorting-associated protein 53, C-terminus | 0.61 | 52.0 | 3.76e-01 | 100.0% | 32.2% |
| 2pg0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 53.0 | 4.09e-01 | 98.4% | 58.4% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.61 | 54.0 | 4.41e-01 | 98.4% | 55.2% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.59 | 52.0 | 4.36e-01 | 100.0% | 92.9% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3182060 | 4168.1.1.0 ↗ | alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain | 0.76 | 51.0 | 4.87e-01 | 84.4% | 60.0% |
| 4511746 | 150.5.1.51 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100_2 | 0.71 | 64.0 | 4.65e-01 | 100.0% | 38.9% |
| 4033102 | 632.5.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylocoagulase › Staphylocoagulase | 0.71 | 63.0 | 5.52e-01 | 100.0% | 81.1% |
| 4217794 | 5086.1.1.94 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD | 0.69 | 61.0 | 4.90e-01 | 98.4% | 96.8% |
| 4304195 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 60.0 | 4.03e-01 | 100.0% | 55.6% |
| 1552160 | 4070.1.1.1 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M41 | 0.66 | 60.0 | 4.19e-01 | 100.0% | 63.8% |
| 3610238 | 4070.1.1.1 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M41 | 0.66 | 59.0 | 4.12e-01 | 100.0% | 69.4% |
| 3597298 | 4070.1.1.0 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like | 0.66 | 59.0 | 4.12e-01 | 100.0% | 69.7% |
| 3175323 | 7015.1.1.1 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC | 0.66 | 58.0 | 3.79e-01 | 100.0% | 23.0% |
| 3270180 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.59 | 52.0 | 4.62e-01 | 96.9% | 72.2% |
D7
medium
residues 746-844
Domain cluster:
rep: ORF6__YP_010084546__Macaca_nemestrina_rhadinovirus_2__123630__D750-828
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00747.23 best | Viral_DNA_bp | 130.8 | 4.50e-38 | 100.0% | 8.6% |