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structural_glycoprotein_E2
Euk-VirPestivirus_giraffe-1_H138
structural_glycoprotein_E2__NP_777524__Pestivirus_giraffe-1_H138__119222
Identity
- Accession:
- NP_777524 ↗
- Protein ID:
- structural_glycoprotein_E2
- Kingdom:
- euk
Quality
84.1
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Pestivirus›
Pestivirus_giraffe-1_H138
TaxID: 119222
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 8-85
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF16329.11 best | Pestivirus_E2 | 71.4 | 9.30e-20 | 100.0% | 20.4% |
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yq2A01 | 2.60.320.20 | Mainly Beta › Sandwich › mini-chromosome maintenance (MCM) complex, domain 2 › Pestivirus envelope glycoprotein E2, domain A | 0.97 | 93.0 | 8.81e-01 | 100.0% | 87.5% |
| 2l04A00 | 2.60.40.1080 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.73 | 45.0 | 4.28e-01 | 100.0% | 52.7% |
| 3pddA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.69 | 45.0 | 4.15e-01 | 100.0% | 51.5% |
| 4b8eB00 | 2.60.120.920 | Mainly Beta › Sandwich › Jelly Rolls › SPRY domain | 0.65 | 54.0 | 4.09e-01 | 92.3% | 84.9% |
| 4pbxA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.59 | 41.0 | 3.95e-01 | 100.0% | 63.0% |
| 2w91A03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.59 | 43.0 | 3.96e-01 | 100.0% | 59.2% |
| 1x5aA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.59 | 39.0 | 3.77e-01 | 100.0% | 59.3% |
| 7u7nA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.57 | 43.0 | 4.02e-01 | 100.0% | 66.0% |
| 1hxmB02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.55 | 42.0 | 3.90e-01 | 100.0% | 62.9% |
| 6rptC00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 42.0 | 3.78e-01 | 100.0% | 60.7% |
| 3pv7A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 43.0 | 4.09e-01 | 100.0% | 75.5% |
| 7y8sB01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 36.0 | 3.57e-01 | 100.0% | 70.1% |
| 3uuwB02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.50 | 34.0 | 2.70e-01 | 70.5% | 65.2% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 185025 | 3539.1.1.1 ↗ | beta sandwiches › N-terminal domain in envelope glycoprotein E2 › N-terminal domain in envelope glycoprotein E2 › N-terminal domain in envelope glycoprotein E2 › Pestivirus_E2 | 0.97 | 93.0 | 8.86e-01 | 100.0% | 88.5% |
| 3597326 | 11.1.4.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like | 0.70 | 52.0 | 4.94e-01 | 100.0% | 67.8% |
| 3560927 | 391.1.1.0 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module | 0.69 | 32.0 | 4.41e-01 | 70.5% | 97.1% |
| 3910257 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.65 | 46.0 | 4.75e-01 | 100.0% | 77.3% |
| 5034826 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.63 | 40.0 | 3.83e-01 | 100.0% | 53.7% |
| 5060182 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.60 | 38.0 | 3.64e-01 | 100.0% | 54.4% |
| 3405662 | 11.1.1.822 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF229 | 0.56 | 41.0 | 4.00e-01 | 100.0% | 68.9% |
| 4981604 | 230.1.1.3 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › PTPS | 0.51 | 42.0 | 3.43e-01 | 92.3% | 98.7% |
D2
medium
residues 197-268
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF16329.11 best | Pestivirus_E2 | 80.4 | 1.80e-22 | 100.0% | 19.4% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 185027 | 3540.1.1.1 ↗ | beta sandwiches › C-terminal region of envelope glycoprotein E2 › C-terminal region of envelope glycoprotein E2 › C-terminal region of envelope glycoprotein E2 › Pestivirus_E2 | 0.97 | 93.0 | 6.74e-01 | 100.0% | 43.1% |
| 4860658 | 11.23.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Ig-like domain in envelope glycoprotein E2 › Ig-like domain in envelope glycoprotein E2 › Pestivirus_E2 | 0.87 | 81.0 | 6.13e-01 | 100.0% | 48.4% |
| 4860656 | 11.23.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Ig-like domain in envelope glycoprotein E2 › Ig-like domain in envelope glycoprotein E2 › Pestivirus_E2 | 0.60 | 42.0 | 4.41e-01 | 79.2% | 81.8% |
D3
medium
residues 274-328
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF16329.11 best | Pestivirus_E2 | 108.6 | 4.60e-31 | 100.0% | 14.8% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ildA03 | 2.60.40.4200 | Mainly Beta › Sandwich › Immunoglobulin-like › Pestivirus envelope glycoprotein E2, C-terminal domain | 0.82 | 69.0 | 5.83e-01 | 100.0% | 57.6% |
| 1g8kC01 | 2.60.40.4210 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.62 | 53.0 | 4.25e-01 | 100.0% | 69.8% |
| 4g6tA00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.61 | 50.0 | 3.79e-01 | 90.9% | 49.2% |
| 4feuF01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.61 | 48.0 | 4.41e-01 | 89.1% | 84.9% |
| 2xq0A01 | 2.60.40.1730 | Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain | 0.60 | 44.0 | 3.18e-01 | 83.6% | 57.5% |
| 3hlkA01 | 2.60.40.2240 | Mainly Beta › Sandwich › Immunoglobulin-like › Acyl-CoA thioester hydrolase/BAAT N-terminal domain | 0.58 | 45.0 | 3.47e-01 | 89.1% | 56.3% |
| 3b5mA01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.56 | 47.0 | 3.76e-01 | 98.2% | 82.4% |
| 1pmhX00 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.54 | 43.0 | 3.15e-01 | 94.5% | 83.1% |
| 8owfA01 | 2.60.40.290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 42.0 | 3.51e-01 | 92.7% | 76.6% |
| 2hljA01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.53 | 39.0 | 3.13e-01 | 87.3% | 79.6% |
| 2nwaA01 | 2.40.240.20 | Mainly Beta › Beta Barrel › Ribosomal Protein L25; Chain P › Hypothetical PUA domain-like; domain 1 | 0.53 | 44.0 | 4.10e-01 | 100.0% | 89.3% |
| 3wj2B00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.52 | 42.0 | 2.71e-01 | 94.5% | 22.3% |
| 3aimA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 42.0 | 2.72e-01 | 94.5% | 24.4% |
| 3o4oC01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 40.0 | 3.43e-01 | 94.5% | 74.7% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4860658 | 11.23.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Ig-like domain in envelope glycoprotein E2 › Ig-like domain in envelope glycoprotein E2 › Pestivirus_E2 | 0.74 | 61.0 | 4.45e-01 | 100.0% | 32.9% |
| 3269854 | 306.3.1.2 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › Img2 | 0.64 | 55.0 | 4.40e-01 | 98.2% | 50.4% |
| 4025788 | 4081.1.1.7 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Ribophorin_I | 0.58 | 47.0 | 3.18e-01 | 94.5% | 48.5% |
| 4106330 | 244.1.1.0 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C | 0.58 | 42.0 | 3.13e-01 | 81.8% | 72.5% |
| 3677446 | 12.5.1.14 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related › DUF1191 | 0.57 | 45.0 | 3.20e-01 | 90.9% | 32.2% |
| 3562130 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.55 | 45.0 | 3.68e-01 | 94.5% | 68.2% |
| 4124934 | 3110.1.1.10 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › PF30401 | 0.54 | 40.0 | 3.22e-01 | 83.6% | 78.2% |
| None | — | 0.54 | 42.0 | 2.69e-01 | 92.7% | 32.7% | |
| 4295259 | 1.1.8.5 ↗ | beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain › tRNA_Me_trans_C | 0.52 | 42.0 | 3.44e-01 | 92.7% | 97.3% |
| 5031616 | 4.26.1.0 ↗ | beta barrels › SH3 › Chromatin protein Cren7 › Chromatin protein Cren7 | 0.52 | 43.0 | 4.32e-01 | 100.0% | 92.7% |
| 3922242 | 11.1.1.179 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 | 0.51 | 40.0 | 3.38e-01 | 90.9% | 57.1% |
| 4580972 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.51 | 41.0 | 3.40e-01 | 94.5% | 69.1% |
| 3245603 | 222.1.1.0 ↗ | a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase | 0.50 | 37.0 | 3.18e-01 | 89.1% | 70.0% |
D4
medium
residues 336-373