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tegument_host_shutoff_protein

Euk-Vir

Meleagrid_alphaherpesvirus_1

tegument_host_shutoff_protein__NP_073335__Meleagrid_alphaherpesvirus_1__37108

Identity

Accession:
NP_073335 ↗
Protein ID:
tegument_host_shutoff_protein
Kingdom:
euk

Quality

72.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Mardivirus› Meleagrid_alphaherpesvirus_1

TaxID: 37108

Cluster

View cluster (65 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 30-84_150-165_382-412
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2zttA00 6.10.140.720 Special › Helix non-globular › Helix Hairpins › 0.62 38.0 4.38e-01 76.5% 84.9%
2pbxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 47.0 3.81e-01 82.4% 87.8%
4hkuB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 44.0 3.80e-01 81.4% 91.3%
2fd5A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 43.0 3.99e-01 78.4% 93.2%
2rn7A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 29.0 3.51e-01 70.6% 78.8%
1rqgA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.54 39.0 3.47e-01 77.5% 56.3%
2n1rA00 1.10.150.90 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 0.51 42.0 3.82e-01 96.1% 66.4%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4932293 2002.1.1.36 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Pterin_bind 0.56 43.0 3.20e-01 88.2% 31.1%
3351969 2007.9.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR 0.53 46.0 3.93e-01 98.0% 81.7%
3967462 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 40.0 3.23e-01 82.4% 78.1%
3284593 1188.1.1.1 ↗ alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip 0.52 45.0 3.47e-01 99.0% 55.1%
1556812 612.1.1.0 ↗ alpha arrays › Retroviral matrix proteins › Retroviral matrix proteins › Retroviral matrix proteins 0.51 42.0 3.82e-01 96.1% 66.4%
D2 medium residues 85-112_166-226_368-381
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00867.24 best XPG_I 30.4 5.80e-07 66.0% 46.6%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5v07Z01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.67 55.0 4.28e-01 86.4% 85.0%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3721945 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.71 55.0 4.40e-01 80.6% 58.9%
4979225 2006.1.4.25 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I 0.71 58.0 4.51e-01 85.4% 88.5%
3781390 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.69 56.0 4.33e-01 85.4% 80.9%
3789016 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.68 57.0 3.97e-01 86.4% 85.9%
3743690 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.68 56.0 4.60e-01 86.4% 53.1%
3808902 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.68 56.0 4.50e-01 85.4% 82.8%
5041361 2006.1.4.25 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I 0.68 53.0 4.59e-01 82.5% 74.8%
4964944 2006.1.4.25 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I 0.67 56.0 4.31e-01 86.4% 85.2%
3484303 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.67 56.0 4.43e-01 86.4% 83.2%
3584243 2006.1.4.25 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I 0.67 51.0 4.69e-01 83.5% 62.3%
4589814 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.67 55.0 4.07e-01 86.4% 85.7%
5049771 2006.1.4.25 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I 0.66 54.0 4.13e-01 86.4% 87.1%
3882124 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.66 54.0 4.15e-01 86.4% 72.1%
4426402 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.66 54.0 4.11e-01 86.4% 82.7%
None — 0.65 54.0 4.10e-01 86.4% 84.5%
3610118 2006.1.4.46 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N, XPG_I, XPG_I_2 0.65 59.0 4.18e-01 96.1% 80.3%
3701288 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.65 53.0 4.07e-01 86.4% 84.5%
4264908 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.65 53.0 4.09e-01 86.4% 80.9%
4001799 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.64 59.0 4.29e-01 98.1% 69.5%
3937112 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.64 58.0 4.27e-01 98.1% 87.6%
3937732 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.63 52.0 4.18e-01 86.4% 83.2%
4020826 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.63 57.0 4.14e-01 95.1% 85.5%
3581443 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.63 58.0 4.02e-01 98.1% 86.6%
4377686 4156.1.1.0 ↗ alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like 0.62 54.0 3.22e-01 91.3% 69.0%
142326 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.62 51.0 3.87e-01 86.4% 84.6%
4028436 2006.1.4.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.61 53.0 3.90e-01 93.2% 70.6%
4028970 2006.1.4.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I 0.61 56.0 4.06e-01 98.1% 69.6%
5041646 2006.1.4.13 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_9 0.53 41.0 3.78e-01 83.5% 69.6%
3937068 2004.1.1.417 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, AAA_21 0.51 38.0 2.52e-01 80.6% 90.8%
D3 medium residues 227-265_320-367
PDB
Domain cluster: rep: tegument_host_shutoff_protein__NP_851901__Macacine_alphaherpesvirus_1__10325__D241-275_382-420