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tegument_host_shutoff_protein

Euk-Vir

Macacine_alphaherpesvirus_1

tegument_host_shutoff_protein__NP_851901__Macacine_alphaherpesvirus_1__10325

Identity

Accession:: NP_851901 ↗
Protein ID:: tegument_host_shutoff_protein
Kingdom:: euk

Quality

74.5 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Macacine_alphaherpesvirus_1

TaxID: 10325

Cluster

View cluster (65 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 28-43_162-190_421-475

PDB

Domain cluster: representative

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4uurA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.54	42.0	3.90e-01	83.0%	92.7%
6fhpD00	1.10.390.10	Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2	0.53	32.0	3.75e-01	81.0%	93.5%
1nklA00	1.10.225.10	Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like	0.53	32.0	3.50e-01	83.0%	75.6%
1wgwA00	1.20.120.140	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain	0.51	35.0	3.61e-01	80.0%	73.7%
2fji102	1.10.357.70	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Exocyst complex component Sec6, C-terminal domain	0.50	40.0	3.24e-01	95.0%	45.3%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2895133	173.1.1.0 ↗	alpha arrays › Uteroglobin-like › Uteroglobin-like › Uteroglobin-like	0.55	36.0	3.87e-01	91.0%	79.8%
3858197	5001.1.1.82 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › WLS-like_TM	0.52	45.0	3.21e-01	99.0%	86.5%
2770597	3209.1.1.1 ↗	a+b two layers › RPL28 › RPL28 › RPL28 › Ribosomal_L28e	0.51	35.0	3.17e-01	94.0%	53.0%

D2 medium residues 241-275_382-420

PDB

Domain cluster: representative

CATH (10)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1w0bA01	1.20.58.420	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP	0.59	42.0	3.95e-01	75.7%	95.7%
3wvoC02	1.10.132.100	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 ›	0.56	47.0	4.01e-01	98.6%	88.5%
5hmlA02	1.10.150.20	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain	0.55	42.0	4.19e-01	85.1%	92.5%
2ntxA02	1.20.58.1310	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 2	0.55	47.0	4.24e-01	95.9%	71.8%
1elkA00	1.25.40.90	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.54	47.0	3.79e-01	100.0%	50.3%
1bh9B00	1.10.20.10	Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A	0.54	33.0	3.19e-01	95.9%	50.6%
1dlcA01	1.20.190.10	Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain	0.54	44.0	3.10e-01	87.8%	56.8%
1dvpA01	1.25.40.90	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.54	47.0	3.89e-01	100.0%	54.3%
1owlA02	1.25.40.80	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.53	44.0	3.85e-01	98.6%	65.9%
1werA02	1.10.506.10	Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1	0.52	42.0	3.47e-01	91.9%	93.2%

ECOD (16)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3922458	150.3.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine	0.57	45.0	3.72e-01	86.5%	62.2%
3679473	109.4.1.15 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS	0.56	48.0	3.94e-01	100.0%	52.1%
3494051	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.55	48.0	3.50e-01	100.0%	34.8%
3739678	5.1.4.74 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Vps16_N	0.55	46.0	2.88e-01	100.0%	16.8%
None	—		0.54	47.0	3.61e-01	98.6%	46.3%
3252673	109.4.1.94 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANTH	0.54	47.0	3.81e-01	100.0%	52.4%
4026062	218.2.1.1 ↗	a+b two layers › Enolase-N/ribosomal protein › Ribosomal protein L22 › Ribosomal protein L22 › Ribosomal_L22	0.53	40.0	3.12e-01	85.1%	35.3%
3173970	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.52	45.0	3.54e-01	100.0%	70.6%
3596822	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.52	45.0	4.04e-01	100.0%	74.5%
3491519	109.4.1.94 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANTH	0.52	44.0	3.76e-01	100.0%	56.2%
3635652	109.4.1.1276 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FAT, HEAT_ATR	0.52	43.0	2.93e-01	97.3%	24.6%
3204880	109.4.1.934 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_ATR	0.51	44.0	3.79e-01	100.0%	63.2%
4021172	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.51	44.0	3.27e-01	100.0%	76.1%
4007927	5065.1.1.3 ↗	alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2	0.50	41.0	2.81e-01	95.9%	76.5%
3742220	109.4.1.307 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tho2	0.50	43.0	2.92e-01	98.6%	25.9%
5056886	219.1.1.51 ↗	a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C39_2	0.50	40.0	3.08e-01	95.9%	91.7%