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tegument_host_shutoff_protein
Euk-VirFruit_bat_alphaherpesvirus_1
tegument_host_shutoff_protein__YP_009042103__Fruit_bat_alphaherpesvirus_1__1343901
Identity
- Accession:
- YP_009042103 ↗
- Protein ID:
- tegument_host_shutoff_protein
- Kingdom:
- euk
Quality
73.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Pteropodid_alphaherpesvirus_1
TaxID: 1343901
Cluster
View cluster (65 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-16_82-108_162-240_428-444
Domain cluster:
rep: tegument_host_shutoff_protein__NP_073335__Meleagrid_alphaherpesvirus_1__37108__D85-112_166-226_368-381
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00867.24 best | XPG_I | 27.6 | 4.10e-06 | 38.1% | 40.9% |
CATH (2)
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4028492 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.74 | 62.0 | 5.17e-01 | 87.8% | 100.0% |
| 4024047 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.74 | 62.0 | 5.12e-01 | 87.1% | 100.0% |
| 4589814 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.74 | 62.0 | 4.99e-01 | 87.1% | 100.0% |
| 3428426 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.73 | 61.0 | 5.30e-01 | 87.1% | 100.0% |
| 3781390 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.73 | 60.0 | 5.11e-01 | 85.6% | 100.0% |
| 3789016 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.73 | 62.0 | 4.71e-01 | 87.8% | 100.0% |
| 3484303 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.73 | 61.0 | 5.41e-01 | 87.1% | 100.0% |
| 3477276 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.73 | 60.0 | 4.93e-01 | 85.6% | 100.0% |
| None | — | 0.73 | 61.0 | 5.08e-01 | 86.3% | 100.0% | |
| 3743690 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.73 | 61.0 | 5.62e-01 | 87.8% | 100.0% |
| 3176999 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.73 | 60.0 | 4.99e-01 | 87.1% | 100.0% |
| 4021778 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.73 | 61.0 | 4.70e-01 | 87.8% | 100.0% |
| 3882124 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.73 | 61.0 | 5.20e-01 | 87.8% | 86.5% |
| 4964944 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.73 | 61.0 | 5.22e-01 | 87.8% | 100.0% |
| 3701288 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.72 | 60.0 | 5.06e-01 | 86.3% | 100.0% |
| 3875510 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.72 | 61.0 | 5.22e-01 | 87.8% | 100.0% |
| 4426402 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.72 | 61.0 | 5.12e-01 | 87.8% | 99.5% |
| 4933316 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.72 | 61.0 | 5.06e-01 | 87.8% | 99.6% |
| 4237276 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.72 | 61.0 | 5.18e-01 | 87.8% | 100.0% |
| 4264908 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.72 | 59.0 | 5.03e-01 | 86.3% | 95.3% |
| 4028346 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.71 | 60.0 | 4.53e-01 | 87.8% | 99.7% |
| 3584243 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.71 | 48.0 | 4.96e-01 | 71.9% | 72.3% |
| 4395983 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.71 | 59.0 | 4.98e-01 | 86.3% | 100.0% |
| 3938152 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.71 | 59.0 | 5.06e-01 | 85.6% | 100.0% |
| 4946948 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.71 | 60.0 | 5.00e-01 | 87.1% | 100.0% |
| 5049771 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.70 | 59.0 | 4.94e-01 | 87.8% | 100.0% |
| 4927168 | 2006.1.4.19 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N | 0.70 | 59.0 | 4.92e-01 | 87.1% | 100.0% |
| 3613309 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.70 | 59.0 | 4.89e-01 | 87.8% | 100.0% |
| 4956546 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.70 | 58.0 | 4.91e-01 | 86.3% | 100.0% |
| 142326 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.69 | 58.0 | 4.81e-01 | 87.1% | 98.2% |
| 4979225 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.69 | 55.0 | 4.77e-01 | 82.0% | 100.0% |
| 3721945 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.69 | 56.0 | 5.02e-01 | 84.9% | 100.0% |
| 5041361 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.68 | 55.0 | 5.30e-01 | 83.5% | 100.0% |
| 4028970 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.68 | 63.0 | 4.99e-01 | 97.8% | 98.9% |
| 3223707 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.68 | 58.0 | 4.73e-01 | 87.8% | 100.0% |
| 3610118 | 2006.1.4.46 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N, XPG_I, XPG_I_2 | 0.68 | 64.0 | 4.95e-01 | 100.0% | 98.9% |
| 3182237 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.68 | 57.0 | 4.96e-01 | 87.8% | 100.0% |
| 3581443 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.67 | 62.0 | 4.69e-01 | 97.8% | 96.7% |
| 3416420 | 2006.1.4.52 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PF27698 | 0.67 | 62.0 | 4.07e-01 | 97.1% | 53.8% |
| 4001799 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.66 | 61.0 | 4.89e-01 | 97.8% | 99.2% |
| 3718837 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.66 | 62.0 | 4.75e-01 | 100.0% | 99.7% |
D2
medium
residues 41-81_445-473
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2f2cA02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.62 | 50.0 | 4.37e-01 | 92.9% | 57.5% |
| 1wwmA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.59 | 46.0 | 3.46e-01 | 85.7% | 72.2% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 50.0 | 4.30e-01 | 100.0% | 90.6% |
| 3ecsC01 | 1.20.120.1070 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain | 0.56 | 49.0 | 4.29e-01 | 94.3% | 90.0% |
| 4rocA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 48.0 | 4.23e-01 | 98.6% | 70.9% |
| 3mdmA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.54 | 43.0 | 2.65e-01 | 87.1% | 28.0% |
| 1so2A00 | 1.10.1300.10 | Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 0.54 | 45.0 | 2.92e-01 | 97.1% | 61.2% |
| 3qx3A04 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.53 | 41.0 | 3.66e-01 | 82.9% | 73.0% |
| 5ywwA01 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.51 | 37.0 | 3.20e-01 | 77.1% | 48.7% |
| 3hzjA03 | 1.10.472.80 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Ypt/Rab-GAP domain of gyp1p, domain 3 | 0.51 | 41.0 | 3.22e-01 | 88.6% | 53.7% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.50 | 39.0 | 3.25e-01 | 84.3% | 75.8% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3966587 | 3352.1.1.46 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › TgpA_N | 0.69 | 56.0 | 4.34e-01 | 90.0% | 52.9% |
| 3421290 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 59.0 | 4.24e-01 | 100.0% | 58.9% |
| 3382335 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.65 | 59.0 | 3.34e-01 | 100.0% | 15.6% |
| 3365794 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.65 | 58.0 | 3.85e-01 | 100.0% | 40.0% |
| 4308067 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.64 | 48.0 | 4.80e-01 | 87.1% | 80.0% |
| 4639417 | 2004.1.1.226 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADDB_N | 0.60 | 50.0 | 2.87e-01 | 92.9% | 57.9% |
| 4004763 | 5069.1.3.74 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › BPD_transp_1 | 0.60 | 42.0 | 3.70e-01 | 75.7% | 100.0% |
| 5040578 | 604.9.1.0 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 | 0.60 | 46.0 | 4.72e-01 | 85.7% | 89.2% |
| 3913373 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 41.0 | 3.43e-01 | 74.3% | 66.7% |
| 3412630 | 101.1.10.7 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C | 0.57 | 48.0 | 3.86e-01 | 92.9% | 47.4% |
| 3886005 | 601.2.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes | 0.57 | 40.0 | 3.43e-01 | 74.3% | 69.6% |
| 4889682 | 11.2.1.20 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › FerB | 0.57 | 43.0 | 3.46e-01 | 85.7% | 58.2% |
| 5043888 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.55 | 41.0 | 4.23e-01 | 85.7% | 87.7% |
| 4940271 | 7000.1.1.0 ↗ | alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS | 0.54 | 42.0 | 3.94e-01 | 87.1% | 67.8% |
| 4940618 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.54 | 42.0 | 4.09e-01 | 87.1% | 76.2% |
| 3673426 | 109.4.1.1279 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long, TPR_24 | 0.53 | 46.0 | 2.77e-01 | 100.0% | 18.8% |
| 5026124 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.52 | 42.0 | 4.33e-01 | 91.4% | 95.4% |
| 3369911 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.52 | 40.0 | 3.73e-01 | 88.6% | 65.6% |
| 3726235 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.51 | 44.0 | 3.18e-01 | 100.0% | 45.3% |
| 3221809 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.50 | 38.0 | 4.09e-01 | 82.9% | 96.7% |
D3
medium
residues 241-274_371-427