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tegument_protein_UL21
Euk-VirHuman_alphaherpesvirus_1
tegument_protein_UL21__YP_009137095__Human_alphaherpesvirus_1__10298
Identity
- Accession:
- YP_009137095 ↗
- Protein ID:
- tegument_protein_UL21
- Kingdom:
- euk
Quality
75.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Human_alphaherpesvirus_1
TaxID: 10298
Cluster
View cluster (29 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 285-390
Domain cluster:
rep: tegument_protein_UL21__YP_009361917__Ateline_alphaherpesvirus_1__35243__D279-385
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03252.19 best | Herpes_UL21 | 144.2 | 8.70e-42 | 100.0% | 20.4% |
D2
high
residues 399-532
Domain cluster:
rep: tegument_protein_UL21__YP_009252265__Canid_alphaherpesvirus_1__170325__D384-522
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03252.19 best | Herpes_UL21 | 151.1 | 6.60e-44 | 92.5% | 23.7% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ichA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.55 | 36.0 | 4.27e-01 | 72.4% | 100.0% |
| 1un8A02 | 1.25.40.340 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain | 0.55 | 41.0 | 3.72e-01 | 79.1% | 94.3% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.55 | 34.0 | 4.04e-01 | 76.9% | 92.2% |
| 4w8kA02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.54 | 41.0 | 3.67e-01 | 81.3% | 92.4% |
| 1wmgA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.53 | 35.0 | 4.07e-01 | 73.1% | 97.8% |
| 2nwlC00 | 1.10.3860.10 | Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter | 0.53 | 41.0 | 2.96e-01 | 81.3% | 79.4% |
| 3w6bB00 | 1.10.530.10 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.53 | 42.0 | 4.05e-01 | 83.6% | 86.9% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.51 | 31.0 | 3.30e-01 | 97.0% | 67.5% |
| 1iduA02 | 1.10.606.10 | Mainly Alpha › Orthogonal Bundle › Vanadium-containing Chloroperoxidase; domain 2 › Vanadium-containing Chloroperoxidase, domain 2 | 0.51 | 43.0 | 3.17e-01 | 95.5% | 83.0% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1828353 | 1064.1.1.1 ↗ | alpha complex topology › Tegument protein UL21 › Tegument protein UL21 › Tegument protein UL21 › Herpes_UL21 | 0.94 | 91.0 | 7.03e-01 | 98.5% | 52.4% |
| 5015275 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.59 | 38.0 | 3.92e-01 | 75.4% | 67.7% |
| 4243254 | 192.29.1.114 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Mitofilin | 0.59 | 34.0 | 3.10e-01 | 73.1% | 42.2% |
| 5062219 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.57 | 38.0 | 3.76e-01 | 77.6% | 62.8% |
| 4967414 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.57 | 38.0 | 3.83e-01 | 78.4% | 66.7% |
| 5007096 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.57 | 37.0 | 3.77e-01 | 75.4% | 67.7% |
| 3708682 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.56 | 49.0 | 4.40e-01 | 94.0% | 77.3% |
| 5068927 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.56 | 35.0 | 3.74e-01 | 74.6% | 72.2% |
| 4939929 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.55 | 35.0 | 3.58e-01 | 80.6% | 63.7% |
| 5007694 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.55 | 36.0 | 3.86e-01 | 78.4% | 75.0% |
| 3290358 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.54 | 36.0 | 3.82e-01 | 77.6% | 75.0% |
| 5025678 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.54 | 37.0 | 3.77e-01 | 78.4% | 71.5% |
| 5066095 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.53 | 36.0 | 3.63e-01 | 76.1% | 66.4% |
| 3603607 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.53 | 36.0 | 3.69e-01 | 78.4% | 71.5% |
| 4014246 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 44.0 | 3.38e-01 | 91.8% | 40.3% |
| 5023506 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.53 | 36.0 | 3.50e-01 | 79.1% | 61.3% |
| 4964693 | 5060.2.1.0 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain | 0.53 | 36.0 | 3.56e-01 | 78.4% | 66.4% |
| 5080467 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.53 | 35.0 | 3.52e-01 | 78.4% | 65.0% |
| 3927985 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.51 | 43.0 | 3.63e-01 | 91.8% | 85.1% |
| 4999943 | 5060.2.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF | 0.51 | 35.0 | 3.60e-01 | 79.1% | 74.4% |
D3
medium
residues 1-55_137-151_170-189_209-223
Domain cluster:
rep: tegument_protein_UL21__YP_443867__Papiine_alphaherpesvirus_2__340907__D1-51_171-191_209-225
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03252.19 best | Herpes_UL21 | 105.4 | 4.90e-30 | 64.8% | 11.8% |
D4
medium
residues 56-136_152-169
Domain cluster:
rep: tegument_protein_UL21__YP_182374__Gallid_alphaherpesvirus_1__10386__D52-162
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03252.19 best | Herpes_UL21 | 122.7 | 2.80e-35 | 100.0% | 20.4% |