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tegument_protein_UL37

Euk-Vir

Gallid_alphaherpesvirus_3

tegument_protein_UL37__NP_066869__Gallid_alphaherpesvirus_3__35250

Identity

Accession:
NP_066869 ↗
Protein ID:
tegument_protein_UL37
Kingdom:
euk

Quality

72.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 582-728
PDB
D2 medium residues 7-145
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03970.19 best Herpes_UL37_1 161.4 3.60e-47 100.0% 52.1%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5cwkA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 55.0 5.16e-01 100.0% 69.6%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 45.0 4.38e-01 92.1% 65.2%
4flbA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 50.0 5.17e-01 99.3% 90.1%
3zgzA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 40.0 3.70e-01 90.6% 50.8%
2diwA01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 50.0 4.98e-01 97.8% 87.9%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 41.0 4.59e-01 83.5% 91.5%
1sz9C00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 47.0 4.70e-01 100.0% 83.6%
3cbuA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 47.0 4.86e-01 87.8% 88.1%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 45.0 4.43e-01 94.2% 75.2%
4i1eA03 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.58 43.0 4.30e-01 77.0% 99.3%
1by1A00 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.54 43.0 3.83e-01 85.6% 78.5%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 47.0 4.39e-01 100.0% 77.6%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.53 44.0 4.33e-01 91.4% 94.8%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.52 40.0 3.92e-01 82.0% 83.2%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1283715 3852.1.1.1 alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 0.94 80.0 5.27e-01 98.6% 25.3%
2098130 3852.1.1.1 alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 0.93 85.0 6.49e-01 100.0% 47.6%
3840925 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.69 54.0 5.11e-01 100.0% 69.7%
3256816 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 49.0 4.77e-01 93.5% 70.0%
3699772 109.4.1.441 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFCD_C 0.65 59.0 3.93e-01 100.0% 25.9%
3398148 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 49.0 3.67e-01 92.8% 34.1%
3928123 109.4.1.44 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35 0.62 56.0 3.89e-01 100.0% 34.8%
3269027 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 45.0 4.41e-01 91.4% 68.4%
3875187 109.4.1.1904 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm, ARM_ARMC5 0.61 55.0 3.98e-01 100.0% 44.5%
3414203 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 51.0 4.50e-01 100.0% 62.9%
3251836 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.58 39.0 4.06e-01 91.4% 73.1%
3720031 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 50.0 4.85e-01 100.0% 85.0%
3650927 109.4.1.170 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CLASP_N 0.57 49.0 4.58e-01 99.3% 74.9%
3716269 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.52 47.0 3.83e-01 98.6% 62.4%
D3 medium residues 146-226
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03970.19 best Herpes_UL37_1 90.2 1.80e-25 100.0% 30.3%
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.75 67.0 4.99e-01 100.0% 47.8%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.73 65.0 5.18e-01 100.0% 67.9%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 65.0 5.46e-01 100.0% 77.9%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 65.0 6.07e-01 100.0% 100.0%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 59.0 6.22e-01 91.4% 100.0%
3fnrA01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.69 56.0 4.71e-01 91.4% 55.2%
2xzeB00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.69 59.0 5.02e-01 97.5% 60.9%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.69 60.0 5.40e-01 100.0% 92.2%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.68 61.0 5.71e-01 100.0% 85.9%
3cegA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.68 60.0 4.13e-01 100.0% 29.8%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 60.0 5.59e-01 100.0% 96.0%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 59.0 5.72e-01 100.0% 96.8%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 60.0 4.78e-01 98.8% 67.9%
8sbeA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.68 49.0 3.73e-01 77.8% 33.7%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.68 59.0 5.40e-01 100.0% 80.0%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 59.0 4.38e-01 98.8% 49.5%
3zheC01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 56.0 4.26e-01 95.1% 39.7%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 58.0 4.60e-01 100.0% 87.2%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 53.0 4.93e-01 86.4% 85.1%
7dl9A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.66 49.0 3.72e-01 79.0% 35.6%
1i1rB00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.65 52.0 4.12e-01 86.4% 73.7%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 55.0 5.01e-01 95.1% 95.5%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 56.0 4.51e-01 100.0% 77.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 53.0 4.75e-01 91.4% 94.0%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.64 50.0 3.42e-01 87.7% 77.2%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 54.0 4.83e-01 96.3% 70.6%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 53.0 4.60e-01 92.6% 68.8%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.63 55.0 5.07e-01 100.0% 77.4%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.63 56.0 4.36e-01 100.0% 57.3%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 53.0 4.43e-01 100.0% 95.6%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 44.0 3.68e-01 76.5% 48.3%
1or4B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 47.0 3.89e-01 87.7% 77.8%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.59 52.0 5.18e-01 97.5% 98.8%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 49.0 4.55e-01 93.8% 84.3%
2qwoB00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.59 42.0 4.04e-01 87.7% 66.3%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.58 49.0 3.76e-01 96.3% 80.7%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 44.0 4.00e-01 80.2% 80.9%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.58 41.0 3.65e-01 74.1% 57.0%
2ykgA03 1.20.1320.30 Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 › 0.58 50.0 4.31e-01 100.0% 60.2%
4iv6B01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.57 44.0 3.98e-01 86.4% 67.2%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.56 38.0 3.92e-01 72.8% 75.0%
1xl3C00 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.56 46.0 4.52e-01 93.8% 91.2%
1txuA02 1.20.1050.80 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › VPS9 domain 0.55 48.0 3.90e-01 97.5% 53.8%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.55 50.0 3.78e-01 100.0% 53.0%
2p35A02 1.10.150.290 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › S-adenosyl-L-methionine-dependent methyltransferases 0.54 35.0 3.79e-01 88.9% 78.6%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.53 45.0 4.10e-01 96.3% 83.5%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 47.0 4.35e-01 100.0% 87.9%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 41.0 3.58e-01 86.4% 68.5%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 43.0 3.36e-01 90.1% 52.9%
1evyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.52 37.0 3.11e-01 76.5% 42.5%
6zhiB02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 44.0 4.44e-01 95.1% 97.6%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.51 39.0 3.46e-01 85.2% 55.6%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.50 36.0 3.73e-01 79.0% 85.9%
ECOD (57)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3844591 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.78 72.0 6.32e-01 100.0% 91.3%
3270160 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.78 70.0 6.57e-01 100.0% 89.0%
5051294 601.41.1.0 alpha bundles › Four-helical up-and-down bundle › C-terminal domain in uncharacterized DUF3829-like protein › C-terminal domain in uncharacterized DUF3829-like protein 0.75 67.0 5.83e-01 100.0% 73.6%
3515526 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.74 66.0 5.59e-01 100.0% 65.2%
4033482 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.74 64.0 6.19e-01 93.8% 100.0%
3588615 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.74 65.0 6.31e-01 97.5% 100.0%
3883669 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.73 63.0 5.27e-01 95.1% 70.0%
4240467 1206.1.1.0 0.73 62.0 5.86e-01 100.0% 77.0%
3577242 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.73 64.0 5.85e-01 98.8% 93.6%
4495127 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 63.0 4.71e-01 96.3% 41.5%
5067572 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.73 64.0 5.94e-01 100.0% 95.2%
3543090 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 64.0 5.88e-01 100.0% 99.0%
4027059 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.71 63.0 5.20e-01 98.8% 59.3%
4011740 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.71 61.0 5.71e-01 97.5% 89.0%
3871543 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 62.0 5.31e-01 100.0% 80.8%
3582234 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 61.0 5.69e-01 97.5% 88.0%
4027713 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 60.0 5.89e-01 100.0% 96.7%
3306390 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.69 59.0 5.41e-01 93.8% 77.1%
3993135 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 60.0 4.59e-01 100.0% 83.6%
5052411 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.69 58.0 5.48e-01 96.3% 93.0%
4972372 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.68 50.0 3.69e-01 77.8% 30.5%
5078097 604.1.1.265 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › HepT-like 0.68 56.0 4.79e-01 90.1% 80.8%
3410979 3745.1.1.1 alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex 0.68 58.0 3.89e-01 96.3% 45.5%
3602716 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.68 58.0 5.15e-01 100.0% 80.8%
4360664 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.67 58.0 4.27e-01 97.5% 70.2%
3577030 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.67 51.0 3.81e-01 82.7% 32.9%
3403601 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.67 51.0 3.88e-01 82.7% 35.9%
5053013 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.66 49.0 3.76e-01 79.0% 35.1%
3569902 604.5.1.43 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › Clusterin 0.66 59.0 4.90e-01 100.0% 62.1%
4995049 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.66 49.0 3.69e-01 79.0% 33.3%
2122584 109.26.1.1 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nucleoporin_C 0.66 55.0 3.34e-01 93.8% 13.8%
3244047 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.65 50.0 3.64e-01 82.7% 32.2%
3210369 603.1.1.108 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27599 0.65 53.0 4.58e-01 91.4% 80.0%
3476494 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.63 55.0 4.67e-01 100.0% 62.9%
4032837 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.63 49.0 3.74e-01 82.7% 37.8%
3220780 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.63 48.0 3.52e-01 82.7% 32.2%
3721346 5050.1.1.12 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TRI12 0.63 46.0 4.09e-01 79.0% 55.8%
4985999 4994.1.1.0 alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like 0.62 49.0 4.93e-01 86.4% 95.0%
3388598 109.4.1.398 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FANCI_S1 0.61 49.0 3.88e-01 90.1% 43.9%
3329547 604.6.1.22 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 0.61 53.0 4.88e-01 100.0% 86.4%
3712266 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.60 49.0 4.27e-01 93.8% 57.8%
3701760 611.3.1.0 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.60 51.0 4.29e-01 95.1% 79.3%
3386740 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.60 50.0 3.73e-01 97.5% 37.8%
3251303 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.60 48.0 4.92e-01 90.1% 97.5%
3599480 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.59 42.0 3.15e-01 75.3% 30.2%
3891314 593.1.1.1 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 0.59 44.0 3.17e-01 79.0% 71.7%
3817914 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 43.0 3.81e-01 80.2% 76.8%
3427778 604.1.1.144 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26575 0.58 46.0 4.62e-01 86.4% 98.8%
3179160 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 44.0 3.31e-01 82.7% 33.2%
3895470 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.56 39.0 3.76e-01 80.2% 62.1%
4937297 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.53 47.0 4.40e-01 100.0% 89.0%
4942062 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.52 47.0 4.62e-01 96.3% 100.0%
4679869 632.15.1.4 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › HSP70 0.52 46.0 4.59e-01 100.0% 96.5%
4591251 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.51 46.0 4.55e-01 100.0% 96.5%
4365789 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.51 46.0 4.46e-01 100.0% 92.2%
3961831 103.4.1.7 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › DUF1290 0.51 43.0 4.01e-01 95.1% 81.0%
171404 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.50 36.0 3.73e-01 79.0% 85.9%
D4 medium residues 227-373
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03970.19 best Herpes_UL37_1 46.7 3.60e-12 29.9% 16.1%
D5 medium residues 374-486
PDB
D6 medium residues 487-541
PDB
D7 medium residues 763-806_880-967
PDB
D8 medium residues 807-879
PDB
Domain cluster: representative
CATH (75)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.95 81.0 7.79e-01 98.6% 80.2%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.95 90.0 7.69e-01 100.0% 83.5%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.94 89.0 6.95e-01 100.0% 68.3%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.94 84.0 7.26e-01 100.0% 65.1%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.93 86.0 8.02e-01 98.6% 82.6%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.93 86.0 7.40e-01 100.0% 67.3%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.92 87.0 6.75e-01 100.0% 52.1%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.92 66.0 7.04e-01 74.0% 100.0%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.92 86.0 6.48e-01 100.0% 74.2%
3sjqC00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.92 63.0 6.12e-01 71.2% 87.5%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.91 83.0 7.24e-01 100.0% 68.0%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.91 75.0 7.96e-01 86.3% 98.4%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.91 65.0 7.08e-01 76.7% 88.5%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.90 84.0 5.36e-01 100.0% 24.9%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.89 83.0 6.18e-01 100.0% 45.2%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.89 80.0 7.84e-01 97.3% 94.9%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.89 83.0 5.75e-01 100.0% 34.9%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.89 81.0 6.99e-01 100.0% 66.7%
3tulB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.89 82.0 6.60e-01 100.0% 57.9%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.89 83.0 7.04e-01 100.0% 65.2%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.88 82.0 6.06e-01 100.0% 45.8%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.87 82.0 7.42e-01 100.0% 93.6%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.87 80.0 6.24e-01 100.0% 77.4%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.87 80.0 7.46e-01 100.0% 90.9%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.87 71.0 7.66e-01 90.4% 100.0%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.87 77.0 7.76e-01 97.3% 95.8%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.86 77.0 7.29e-01 97.3% 83.7%
2qe7G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.86 78.0 7.05e-01 100.0% 86.6%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.85 73.0 5.65e-01 93.2% 44.5%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.85 74.0 6.89e-01 93.2% 81.1%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.85 71.0 6.66e-01 89.0% 94.3%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.85 77.0 6.70e-01 100.0% 70.6%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.84 65.0 6.10e-01 90.4% 68.6%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.84 73.0 6.47e-01 91.8% 98.0%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.84 67.0 4.10e-01 84.9% 15.3%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.83 79.0 6.87e-01 100.0% 72.8%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 75.0 6.54e-01 100.0% 68.2%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.82 73.0 6.58e-01 98.6% 77.0%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.82 74.0 6.64e-01 98.6% 78.8%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 77.0 6.63e-01 100.0% 72.6%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 68.0 6.27e-01 93.2% 71.3%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 65.0 6.58e-01 91.8% 87.7%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.80 73.0 4.66e-01 100.0% 63.1%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.80 72.0 6.41e-01 98.6% 77.5%
1rfyB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.80 72.0 6.70e-01 97.3% 79.5%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.79 70.0 5.23e-01 100.0% 88.5%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 70.0 6.26e-01 98.6% 70.6%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.79 68.0 6.17e-01 94.5% 72.2%
1fxkC00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 70.0 5.75e-01 100.0% 91.0%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.78 63.0 6.16e-01 86.3% 84.6%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.78 69.0 5.99e-01 100.0% 64.0%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.78 61.0 6.01e-01 83.6% 98.7%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 70.0 5.36e-01 100.0% 46.0%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.77 64.0 5.38e-01 90.4% 55.5%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.77 63.0 5.59e-01 94.5% 62.6%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.76 60.0 6.31e-01 87.7% 95.4%
2etnB01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.76 62.0 6.18e-01 93.2% 86.8%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 66.0 5.44e-01 98.6% 56.6%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 67.0 4.71e-01 100.0% 31.9%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 62.0 6.31e-01 90.4% 94.4%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.75 66.0 6.54e-01 100.0% 93.5%
3g80A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.75 59.0 5.91e-01 86.3% 84.9%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 60.0 6.31e-01 89.0% 100.0%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.74 54.0 5.85e-01 91.8% 98.3%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 63.0 5.69e-01 100.0% 70.3%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.73 63.0 5.75e-01 100.0% 72.5%
3jcuZ00 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.72 55.0 5.91e-01 83.6% 100.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.72 64.0 6.09e-01 100.0% 91.8%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.72 59.0 5.04e-01 91.8% 55.9%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.71 60.0 5.74e-01 94.5% 83.7%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 59.0 5.91e-01 97.3% 100.0%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.67 59.0 5.92e-01 100.0% 100.0%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 50.0 4.99e-01 83.6% 76.9%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.67 58.0 5.83e-01 98.6% 100.0%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.64 55.0 4.39e-01 100.0% 48.1%
ECOD (78)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3237264 3755.4.1.82 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Snf7 0.96 89.0 7.12e-01 97.3% 54.6%
4024396 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.96 92.0 7.20e-01 100.0% 54.1%
4977416 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.95 91.0 6.04e-01 100.0% 30.5%
58691 4177.1.1.3 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin 0.95 90.0 7.26e-01 100.0% 76.6%
4604091 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.95 90.0 7.93e-01 100.0% 80.0%
3686252 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.94 90.0 6.27e-01 100.0% 43.5%
3507969 3755.3.1.420 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PTHB1_hp 0.94 89.0 6.47e-01 100.0% 41.7%
3876221 5.1.12.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › PERK and Ire1 luminal domains › KIF21A 0.94 89.0 6.71e-01 100.0% 49.0%
3409209 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.94 89.0 7.31e-01 100.0% 60.8%
3865253 209.1.1.1 a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C 0.93 88.0 5.53e-01 100.0% 22.6%
3493358 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.93 84.0 7.78e-01 100.0% 77.8%
3595968 605.2.1.0 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 0.93 81.0 7.87e-01 91.8% 85.0%
3707236 3291.1.1.16 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Flagellar_rod 0.93 88.0 6.40e-01 100.0% 41.7%
4275409 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.93 88.0 7.46e-01 100.0% 66.4%
3991023 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.93 82.0 7.25e-01 93.2% 68.0%
5062807 1203.1.2.0 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.93 87.0 5.18e-01 100.0% 76.9%
3462288 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.92 84.0 7.72e-01 100.0% 77.8%
3764842 209.1.1.1 a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C 0.92 87.0 5.53e-01 100.0% 23.9%
3785314 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.92 87.0 5.78e-01 100.0% 44.1%
4052416 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.92 75.0 7.25e-01 84.9% 86.3%
4619538 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.92 87.0 7.28e-01 100.0% 63.5%
3562523 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.92 86.0 6.34e-01 100.0% 42.9%
3176480 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.92 83.0 7.67e-01 100.0% 78.7%
4206858 4992.1.1.23 extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N 0.92 87.0 7.25e-01 100.0% 63.5%
3592652 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.92 86.0 6.02e-01 100.0% 35.6%
3919840 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.91 86.0 5.87e-01 100.0% 33.2%
3600080 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.91 83.0 5.20e-01 97.3% 21.9%
3366371 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.91 85.0 5.57e-01 100.0% 44.1%
3694749 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.91 78.0 5.16e-01 100.0% 25.9%
4260979 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.91 86.0 5.61e-01 100.0% 27.5%
3319132 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.91 84.0 6.63e-01 100.0% 52.1%
3595675 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.90 85.0 5.79e-01 100.0% 32.9%
3906191 4323.1.1.1 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.90 84.0 6.41e-01 100.0% 52.3%
3184698 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.90 84.0 7.79e-01 100.0% 81.1%
4045531 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.90 85.0 7.10e-01 100.0% 63.5%
3699468 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.90 85.0 5.95e-01 100.0% 36.5%
3276646 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.90 84.0 6.54e-01 100.0% 51.4%
3732397 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.90 83.0 6.93e-01 100.0% 60.8%
4028874 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.90 84.0 5.36e-01 100.0% 33.1%
3715005 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.90 83.0 6.29e-01 100.0% 63.7%
3273065 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.89 83.0 5.10e-01 100.0% 19.2%
3409871 2003.1.2.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.89 83.0 4.85e-01 100.0% 13.6%
3764851 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.89 83.0 7.65e-01 100.0% 85.6%
3361950 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.89 82.0 5.61e-01 100.0% 32.2%
3219759 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.89 80.0 6.34e-01 98.6% 51.9%
4946455 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.89 80.0 7.72e-01 97.3% 93.8%
4978412 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.89 78.0 5.69e-01 93.2% 38.9%
3848917 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.88 81.0 7.63e-01 98.6% 89.4%
3660998 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.88 81.0 4.87e-01 100.0% 23.4%
3226449 5001.1.1.34 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srb 0.88 81.0 5.23e-01 100.0% 24.3%
4051951 605.2.1.0 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 0.88 80.0 7.42e-01 97.3% 81.1%
3565133 3755.3.1.44 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › JMY 0.88 82.0 6.80e-01 100.0% 60.8%
3468090 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.88 82.0 6.89e-01 100.0% 67.0%
3289986 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.87 81.0 6.23e-01 100.0% 49.3%
4021462 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.87 81.0 4.69e-01 100.0% 35.9%
4998236 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.87 79.0 4.71e-01 100.0% 15.6%
3258119 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.86 80.0 5.51e-01 100.0% 33.8%
3933048 4992.1.1.12 extended segments › RelB-like › RelB-like › RelB-like › LIN9_C 0.86 80.0 7.10e-01 100.0% 77.0%
3530085 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.86 78.0 4.62e-01 100.0% 25.0%
3207548 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 78.0 6.19e-01 100.0% 75.7%
5059270 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.85 79.0 6.44e-01 100.0% 59.2%
3465588 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.84 75.0 6.55e-01 95.9% 72.4%
3804036 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 74.0 6.37e-01 100.0% 63.5%
4005034 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.82 77.0 5.69e-01 100.0% 43.5%
4652719 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.82 71.0 6.49e-01 98.6% 72.6%
3495507 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 72.0 5.54e-01 100.0% 80.0%
3167271 192.8.1.385 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Med11 0.81 66.0 6.48e-01 90.4% 83.7%
4022378 3860.1.1.0 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm 0.81 72.0 4.79e-01 100.0% 30.0%
3494616 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.80 58.0 5.53e-01 76.7% 85.9%
3168493 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 73.0 5.51e-01 100.0% 75.2%
4674184 2004.1.1.798 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15, AAA_29 0.79 72.0 4.48e-01 100.0% 18.7%
4405271 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.77 68.0 5.37e-01 100.0% 49.0%
3476331 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.77 69.0 5.75e-01 100.0% 58.4%
4000107 3567.1.1.122 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › BAR 0.77 68.0 5.28e-01 100.0% 47.5%
3543713 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.76 67.0 6.33e-01 100.0% 93.3%
3941012 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.76 67.0 4.19e-01 100.0% 19.2%
3282651 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.74 64.0 3.88e-01 100.0% 15.8%
4392833 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 63.0 4.53e-01 98.6% 65.6%