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tegument_protein_UL37
Euk-VirMeleagrid_alphaherpesvirus_1
tegument_protein_UL37__NP_073331__Meleagrid_alphaherpesvirus_1__37108
Identity
- Accession:
- NP_073331 ↗
- Protein ID:
- tegument_protein_UL37
- Kingdom:
- euk
Quality
71.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Mardivirus›
Meleagrid_alphaherpesvirus_1
TaxID: 37108
Cluster
View cluster (7 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 580-721
Domain cluster:
rep: tegument_protein_UL37__YP_009137112__Human_alphaherpesvirus_1__10298__D597-729
D2
high
residues 732-887
Domain cluster:
rep: tegument_protein_UL37__YP_182366__Gallid_alphaherpesvirus_1__10386__D706-889
D3
medium
residues 6-142
Domain cluster:
rep: tegument_protein_UL37__NP_040144__Human_alphaherpesvirus_3__10335__D1-130
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03970.19 best | Herpes_UL37_1 | 165.4 | 2.30e-48 | 99.3% | 51.3% |
D4
medium
residues 143-228
Domain cluster:
rep: tegument_protein_UL37__NP_066869__Gallid_alphaherpesvirus_3__35250__D146-226
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03970.19 best | Herpes_UL37_1 | 97.7 | 9.70e-28 | 100.0% | 31.8% |
D5
medium
residues 229-343
Domain cluster:
rep: tegument_protein_UL37__YP_009176900__Testudinid_alphaherpesvirus_3__2560801__D261-389
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03970.19 best | Herpes_UL37_1 | 43.3 | 3.80e-11 | 36.5% | 15.7% |
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.53 | 43.0 | 4.25e-01 | 88.7% | 94.4% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.51 | 40.0 | 3.51e-01 | 85.2% | 72.5% |
| 7wf6A01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.50 | 39.0 | 3.71e-01 | 84.3% | 79.1% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.50 | 39.0 | 3.97e-01 | 84.3% | 95.7% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.88 | 80.0 | 5.08e-01 | 100.0% | 22.6% |
| 3493998 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 36.0 | 2.71e-01 | 74.8% | 27.0% |
| 3658835 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 41.0 | 4.08e-01 | 83.5% | 92.5% |
| 5020623 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.52 | 43.0 | 4.27e-01 | 89.6% | 96.6% |
| 3212271 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.52 | 41.0 | 3.72e-01 | 84.3% | 82.5% |
| 3964502 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.51 | 40.0 | 4.13e-01 | 83.5% | 97.3% |
| 1503807 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.50 | 39.0 | 3.97e-01 | 83.5% | 94.8% |
D6
medium
residues 344-491
Domain cluster:
rep: tegument_protein_UL37__YP_068340__Suid_alphaherpesvirus_1__10345__D296-434
D7
medium
residues 492-544
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4mycA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.75 | 62.0 | 3.87e-01 | 98.1% | 17.1% |
| 1q16B03 | 1.10.3650.10 | Mainly Alpha › Orthogonal Bundle › nitrate reductase domain fold › nitrate reductase domain like | 0.72 | 52.0 | 4.57e-01 | 77.4% | 84.4% |
| 2j5iA02 | 6.10.250.2850 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.70 | 47.0 | 5.18e-01 | 73.6% | 100.0% |
| 1tmxB00 | 2.60.130.10 | Mainly Beta › Sandwich › Protocatechuate 3,4-Dioxygenase, subunit A › Aromatic compound dioxygenase | 0.69 | 55.0 | 3.52e-01 | 92.5% | 17.1% |
| 3h7aA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.65 | 47.0 | 3.13e-01 | 77.4% | 42.0% |
| 1kmiZ02 | 1.10.287.500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 56.0 | 4.24e-01 | 100.0% | 87.3% |
| 3h1nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 52.0 | 4.15e-01 | 100.0% | 85.8% |
| 4ap9A02 | 1.10.150.210 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 | 0.61 | 40.0 | 3.92e-01 | 73.6% | 61.7% |
| 4hwgA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.57 | 45.0 | 2.98e-01 | 86.8% | 29.4% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 49.0 | 3.88e-01 | 100.0% | 81.2% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4971240 | 1076.1.1.1 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like | 0.77 | 67.0 | 4.27e-01 | 100.0% | 49.4% |
| 4323124 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.73 | 61.0 | 3.79e-01 | 100.0% | 17.0% |
| 3250617 | 140.1.1.4 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 | 0.69 | 57.0 | 3.81e-01 | 100.0% | 28.9% |
| 3244309 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.68 | 53.0 | 3.53e-01 | 92.5% | 20.0% |
| 4371007 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.68 | 52.0 | 4.64e-01 | 96.2% | 56.5% |
| 3170253 | 632.3.1.11 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain › SUV3_C | 0.67 | 55.0 | 4.90e-01 | 88.7% | 66.7% |
D8
medium
residues 974-1033