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tegument_protein_UL37
Euk-VirHuman_alphaherpesvirus_1
tegument_protein_UL37__YP_009137112__Human_alphaherpesvirus_1__10298
Identity
- Accession:
- YP_009137112 ↗
- Protein ID:
- tegument_protein_UL37
- Kingdom:
- euk
Quality
73.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Human_alphaherpesvirus_1
TaxID: 10298
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 68-194_208-227_521-580
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03970.19 best | Herpes_UL37_1 | 217.4 | 3.20e-64 | 74.4% | 58.4% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 41.0 | 4.80e-01 | 71.5% | 97.9% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 30.0 | 3.66e-01 | 84.1% | 70.6% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.59 | 40.0 | 4.25e-01 | 71.5% | 77.2% |
| 1m57A00 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.56 | 49.0 | 3.64e-01 | 94.7% | 69.3% |
| 3uonA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 46.0 | 4.18e-01 | 92.8% | 77.4% |
| 4c0eA01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 38.0 | 3.40e-01 | 82.1% | 52.7% |
| 1w07A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 32.0 | 3.54e-01 | 85.5% | 72.6% |
| 2id3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 32.0 | 3.79e-01 | 78.3% | 88.0% |
| 4b0zA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 35.0 | 3.45e-01 | 71.5% | 61.7% |
| 3ucaA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.52 | 45.0 | 4.15e-01 | 95.2% | 98.9% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.50 | 31.0 | 3.06e-01 | 79.7% | 55.2% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2098130 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.98 | 69.0 | 6.09e-01 | 71.0% | 58.2% |
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.89 | 83.0 | 6.02e-01 | 95.7% | 94.2% |
| 3709939 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 57.0 | 5.16e-01 | 96.6% | 78.6% |
| 3425142 | 5000.4.1.3 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › DUF4220 | 0.62 | 55.0 | 5.08e-01 | 95.7% | 88.5% |
| 3458947 | 604.5.1.72 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › DUF4220 | 0.61 | 54.0 | 5.14e-01 | 95.2% | 90.6% |
| 3253843 | 109.4.1.470 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS2 | 0.57 | 33.0 | 3.43e-01 | 90.8% | 58.9% |
| 3741179 | 601.3.1.13 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › TMEM33_Pom33 | 0.55 | 39.0 | 3.82e-01 | 72.0% | 98.7% |
| 3228662 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.55 | 47.0 | 4.30e-01 | 93.2% | 72.5% |
| 3369382 | 604.5.1.7 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ALMT | 0.54 | 41.0 | 3.84e-01 | 77.3% | 91.4% |
| 3708648 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 48.0 | 4.12e-01 | 95.2% | 66.2% |
| 4947466 | 3281.1.1.1 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M | 0.53 | 47.0 | 3.67e-01 | 98.1% | 73.4% |
| 3366419 | 109.4.1.628 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec7-like_HUS | 0.51 | 38.0 | 2.47e-01 | 82.6% | 18.4% |
| 3715189 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.50 | 44.0 | 3.86e-01 | 93.7% | 77.4% |
D2
medium
residues 242-306
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03970.19 best | Herpes_UL37_1 | 80.3 | 1.90e-22 | 92.3% | 21.7% |
CATH (36)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.71 | 61.0 | 5.82e-01 | 95.4% | 89.3% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.68 | 57.0 | 5.53e-01 | 95.4% | 100.0% |
| 4ikhA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.68 | 54.0 | 4.35e-01 | 87.7% | 68.5% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 56.0 | 4.34e-01 | 93.8% | 61.1% |
| 3fp3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 59.0 | 4.58e-01 | 96.9% | 64.4% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 55.0 | 4.90e-01 | 90.8% | 84.6% |
| 4fnvA01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.65 | 58.0 | 3.61e-01 | 100.0% | 30.5% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.65 | 55.0 | 4.99e-01 | 95.4% | 93.3% |
| 2i2xB01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.64 | 54.0 | 4.82e-01 | 100.0% | 94.0% |
| 3kfwX03 | 1.20.58.1460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 55.0 | 5.25e-01 | 95.4% | 94.7% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 52.0 | 4.50e-01 | 95.4% | 91.8% |
| 2guzB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.62 | 45.0 | 4.55e-01 | 80.0% | 86.2% |
| 4l7nA01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.62 | 44.0 | 3.47e-01 | 84.6% | 35.0% |
| 3nzpB03 | 1.20.58.930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 51.0 | 4.81e-01 | 93.8% | 86.1% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.60 | 45.0 | 4.29e-01 | 81.5% | 82.1% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 47.0 | 4.09e-01 | 90.8% | 91.7% |
| 4qhpA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.59 | 50.0 | 3.27e-01 | 100.0% | 27.2% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.59 | 45.0 | 3.89e-01 | 86.2% | 85.6% |
| 5bovB00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.58 | 49.0 | 3.21e-01 | 96.9% | 74.8% |
| 4jdxF00 | 6.10.140.1840 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 40.0 | 3.68e-01 | 87.7% | 54.4% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 43.0 | 3.78e-01 | 83.1% | 60.8% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.57 | 45.0 | 3.94e-01 | 89.2% | 92.2% |
| 4j0eA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.57 | 40.0 | 2.90e-01 | 76.9% | 32.7% |
| 3di1A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.57 | 42.0 | 2.71e-01 | 78.5% | 41.7% |
| 1cpcB00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.56 | 44.0 | 3.30e-01 | 87.7% | 53.5% |
| 2v40A02 | 1.10.300.10 | Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 | 0.56 | 45.0 | 4.13e-01 | 90.8% | 65.9% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.56 | 44.0 | 3.92e-01 | 89.2% | 97.9% |
| 1f6kC00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.55 | 43.0 | 2.78e-01 | 83.1% | 43.2% |
| 1nklA00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.55 | 39.0 | 3.73e-01 | 78.5% | 62.8% |
| 4n4pD00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.54 | 42.0 | 2.74e-01 | 83.1% | 42.4% |
| 1b8dA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.54 | 43.0 | 3.30e-01 | 89.2% | 52.4% |
| 7lvlA01 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.53 | 42.0 | 2.77e-01 | 87.7% | 20.8% |
| 4xkyA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.51 | 41.0 | 2.74e-01 | 92.3% | 41.3% |
| 3cprA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.51 | 41.0 | 2.64e-01 | 87.7% | 29.8% |
| 1np7A02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 40.0 | 3.42e-01 | 92.3% | 61.3% |
| 1pc3A01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.51 | 41.0 | 3.29e-01 | 92.3% | 94.3% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2098130 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.94 | 89.0 | 5.62e-01 | 100.0% | 23.6% |
| 3588615 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 59.0 | 5.37e-01 | 96.9% | 97.8% |
| 4380838 | 109.4.1.45 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BTAD | 0.69 | 57.0 | 4.28e-01 | 90.8% | 56.9% |
| 3285486 | 109.4.1.45 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BTAD | 0.69 | 59.0 | 4.45e-01 | 95.4% | 98.8% |
| 3583791 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.69 | 55.0 | 4.28e-01 | 86.2% | 48.1% |
| 4014764 | 109.4.1.913 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_TBCD | 0.68 | 48.0 | 3.15e-01 | 75.4% | 18.6% |
| 5051158 | 3651.1.1.0 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain | 0.66 | 58.0 | 4.91e-01 | 100.0% | 91.8% |
| 3882300 | 7087.1.1.1 ↗ | alpha bundles › Emopamil binding protein (EBP) transmembrane domain › Emopamil binding protein (EBP) transmembrane domain › Emopamil binding protein (EBP) transmembrane domain › EBP | 0.66 | 56.0 | 4.13e-01 | 95.4% | 58.9% |
| 3555742 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.65 | 54.0 | 5.09e-01 | 100.0% | 89.4% |
| 3170874 | 109.4.1.2352 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29558, PF29954, PF29957 | 0.65 | 55.0 | 3.22e-01 | 100.0% | 16.1% |
| 5029796 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.64 | 44.0 | 3.62e-01 | 72.3% | 60.8% |
| 3621979 | 3198.1.1.1 ↗ | alpha bundles › ABA-1 repeat unit › ABA-1 repeat unit › ABA-1 repeat unit › NPA | 0.63 | 49.0 | 4.12e-01 | 87.7% | 50.8% |
| 4466183 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.63 | 52.0 | 4.56e-01 | 95.4% | 87.6% |
| 3224841 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.61 | 51.0 | 4.11e-01 | 92.3% | 72.8% |
| 3188288 | 109.4.1.268 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › LARP1_HEAT | 0.59 | 48.0 | 4.11e-01 | 98.5% | 90.8% |
| 4365191 | 141.1.1.2 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › SQS_PSY | 0.57 | 49.0 | 3.03e-01 | 95.4% | 32.6% |
| 3941188 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 47.0 | 3.99e-01 | 100.0% | 80.0% |
| 5079626 | 316.1.1.18 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › AbiEii | 0.54 | 46.0 | 3.28e-01 | 100.0% | 40.0% |
| 4958038 | 2002.1.1.29 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DHDPS | 0.54 | 40.0 | 2.60e-01 | 78.5% | 41.0% |
| 3798361 | 193.1.1.0 ↗ | alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like | 0.53 | 40.0 | 3.30e-01 | 83.1% | 66.4% |
| 3495156 | 109.58.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA repair protein Rev1 C-terminal domain › DNA repair protein Rev1 C-terminal domain › REV1_C | 0.53 | 42.0 | 3.97e-01 | 92.3% | 77.6% |
| 1395462 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.52 | 39.0 | 3.30e-01 | 86.2% | 51.6% |
D3
medium
residues 307-370
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5hzlB01 | 3.80.10.10 | Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor | 0.53 | 43.0 | 3.12e-01 | 92.2% | 61.6% |
| 3p2hA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.52 | 38.0 | 2.84e-01 | 81.2% | 59.2% |
D4
medium
residues 371-520
Domain cluster:
rep: tegument_protein_UL37__YP_068340__Suid_alphaherpesvirus_1__10345__D296-434
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.65 | 46.0 | 5.31e-01 | 99.3% | 99.1% |
| 7ldgA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 46.0 | 4.08e-01 | 99.3% | 55.9% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.57 | 37.0 | 4.01e-01 | 71.3% | 76.4% |
| 4crwA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 41.0 | 3.65e-01 | 96.7% | 54.0% |
| 5cy5B00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.53 | 41.0 | 4.12e-01 | 79.3% | 91.3% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.53 | 35.0 | 4.16e-01 | 93.3% | 99.0% |
| 2qibB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 40.0 | 3.60e-01 | 100.0% | 58.2% |
| 2onkC00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.52 | 43.0 | 3.62e-01 | 87.3% | 76.2% |
| 4hkuB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 42.0 | 4.01e-01 | 100.0% | 75.1% |
| 2ajaA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.51 | 43.0 | 3.35e-01 | 91.3% | 43.4% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 35.0 | 3.82e-01 | 88.7% | 88.9% |
| 3zc0D00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 43.0 | 4.01e-01 | 93.3% | 90.9% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.92 | 76.0 | 5.09e-01 | 100.0% | 26.3% |
| 4132802 | 507.1.1.1 ↗ | alpha arrays › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB | 0.60 | 36.0 | 3.65e-01 | 87.3% | 58.7% |
| 3601804 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 50.0 | 4.08e-01 | 100.0% | 88.5% |
| 3853711 | 109.4.1.1224 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_DOCK9 | 0.56 | 49.0 | 3.79e-01 | 97.3% | 66.9% |
| 3453655 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 33.0 | 3.56e-01 | 93.3% | 68.0% |
| 5047093 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.54 | 39.0 | 3.58e-01 | 74.0% | 76.4% |
| 3435257 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 34.0 | 3.67e-01 | 96.0% | 74.4% |
| 3476318 | 109.34.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › 26S proteasome subunit Rpn2 N-terminal domain › 26S proteasome subunit Rpn2 N-terminal domain › RPN1_RPN2_N | 0.53 | 38.0 | 3.04e-01 | 100.0% | 34.9% |
| 3866268 | 109.4.1.235 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 | 0.53 | 45.0 | 3.80e-01 | 94.7% | 55.9% |
| 4017969 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 47.0 | 3.26e-01 | 100.0% | 56.7% |
| 3250614 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 44.0 | 3.93e-01 | 93.3% | 70.9% |
| 3910413 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 40.0 | 3.70e-01 | 89.3% | 63.1% |
| 3808736 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 45.0 | 3.84e-01 | 99.3% | 89.0% |
| 3405149 | 5000.6.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Tethering factor for nuclear proteasome cut8 › Tethering factor for nuclear proteasome cut8 › Cut8 | 0.50 | 43.0 | 3.96e-01 | 98.7% | 71.8% |
| 3655114 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 38.0 | 3.89e-01 | 94.7% | 84.3% |
| 5071234 | 4070.1.1.2 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 | 0.50 | 38.0 | 3.53e-01 | 79.3% | 84.5% |
| 3252711 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 43.0 | 2.98e-01 | 100.0% | 24.8% |
| 3801633 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.50 | 39.0 | 3.86e-01 | 80.7% | 95.5% |
D5
medium
residues 597-729
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.77 | 58.0 | 6.43e-01 | 77.4% | 100.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.76 | 56.0 | 6.02e-01 | 75.9% | 98.2% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.75 | 55.0 | 5.63e-01 | 75.9% | 82.0% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.75 | 58.0 | 5.19e-01 | 81.2% | 70.7% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.74 | 46.0 | 5.70e-01 | 74.4% | 100.0% |
| 1sj7C00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.73 | 54.0 | 5.00e-01 | 75.9% | 74.7% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 53.0 | 5.43e-01 | 76.7% | 95.4% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.72 | 53.0 | 5.97e-01 | 86.5% | 100.0% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 64.0 | 5.48e-01 | 100.0% | 91.9% |
| 2vpzC00 | 1.20.1630.10 | Mainly Alpha › Up-down Bundle › Formate dehydrogenase/DMSO reductase fold › Formate dehydrogenase/DMSO reductase domain | 0.67 | 52.0 | 4.26e-01 | 82.7% | 92.4% |
| 1bbhA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.67 | 50.0 | 5.12e-01 | 78.9% | 100.0% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.64 | 52.0 | 5.54e-01 | 85.7% | 100.0% |
| 3fhnA03 | 1.10.357.100 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Dsl1p vesicle tethering complex, Tip20p subunit, domain C | 0.58 | 42.0 | 3.86e-01 | 74.4% | 81.0% |
| 5dqqA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.58 | 45.0 | 4.59e-01 | 82.0% | 95.3% |
| 3tm8B00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.57 | 45.0 | 3.49e-01 | 83.5% | 84.7% |
| 4qreA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.54 | 45.0 | 4.17e-01 | 90.2% | 94.2% |
| 1izmA00 | 1.20.120.740 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YgfB uncharacterised protein family PF03695 | 0.53 | 44.0 | 4.10e-01 | 90.2% | 78.2% |
| 2xgjA03 | 1.10.3380.30 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › | 0.53 | 43.0 | 3.73e-01 | 88.7% | 80.0% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.53 | 44.0 | 3.22e-01 | 94.0% | 74.3% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5074120 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.74 | 52.0 | 5.98e-01 | 88.7% | 100.0% |
| 3519442 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.72 | 56.0 | 5.28e-01 | 80.5% | 89.7% |
| 3718416 | 601.16.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.72 | 60.0 | 5.71e-01 | 88.7% | 80.0% |
| 3487768 | 601.16.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.71 | 54.0 | 5.35e-01 | 78.9% | 97.9% |
| 5074606 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.71 | 51.0 | 5.76e-01 | 78.9% | 100.0% |
| 3401856 | 601.34.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › F-actin binding domain of Abl › F-actin binding domain of Abl › F_actin_bind | 0.68 | 53.0 | 5.71e-01 | 81.2% | 100.0% |
| 3704187 | 601.28.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 | 0.68 | 51.0 | 5.51e-01 | 91.7% | 94.5% |
| 3464862 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.68 | 52.0 | 4.26e-01 | 79.7% | 70.0% |
| 4609538 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 51.0 | 5.46e-01 | 79.7% | 91.3% |
| 2539030 | 601.2.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Cytochrom_C_2 | 0.67 | 53.0 | 5.76e-01 | 86.5% | 100.0% |
| 4944703 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 51.0 | 5.21e-01 | 83.5% | 100.0% |
| 5010969 | 5069.1.1.105 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF973 | 0.65 | 55.0 | 5.38e-01 | 99.2% | 82.8% |
| 4879693 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.64 | 50.0 | 5.01e-01 | 82.0% | 92.7% |
| 3261143 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.58 | 46.0 | 4.21e-01 | 83.5% | 83.9% |
| 5018475 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 46.0 | 4.78e-01 | 97.0% | 94.2% |
| 3727319 | 601.1.1.77 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF3176 | 0.56 | 47.0 | 4.26e-01 | 92.5% | 93.5% |
| 4998788 | 3236.1.1.1 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger | 0.55 | 47.0 | 3.40e-01 | 94.0% | 72.5% |
| 3703129 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 41.0 | 3.65e-01 | 79.7% | 78.0% |
| 4376682 | 604.39.1.26 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › 5TM-5TMR_LYT | 0.52 | 41.0 | 3.75e-01 | 84.2% | 98.9% |
| 3355425 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 39.0 | 3.67e-01 | 82.0% | 77.1% |
D6
medium
residues 741-972
Domain cluster:
rep: tegument_protein_UL37__YP_182366__Gallid_alphaherpesvirus_1__10386__D706-889
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 43.0 | 5.89e-01 | 83.2% | 99.2% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.80 | 50.0 | 5.83e-01 | 71.1% | 85.7% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.79 | 36.0 | 5.47e-01 | 86.2% | 100.0% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.77 | 37.0 | 5.38e-01 | 70.7% | 100.0% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.76 | 37.0 | 5.35e-01 | 88.8% | 98.2% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.76 | 38.0 | 4.25e-01 | 90.9% | 58.6% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.76 | 37.0 | 5.34e-01 | 90.5% | 100.0% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 42.0 | 5.54e-01 | 83.2% | 97.6% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.76 | 39.0 | 5.50e-01 | 91.4% | 100.0% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.74 | 45.0 | 5.29e-01 | 86.6% | 84.1% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.74 | 36.0 | 3.89e-01 | 83.2% | 53.0% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 35.0 | 3.75e-01 | 84.9% | 53.4% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.67 | 53.0 | 5.46e-01 | 81.0% | 90.6% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 46.0 | 4.71e-01 | 72.4% | 80.2% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.62 | 32.0 | 4.49e-01 | 96.6% | 100.0% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 29.0 | 3.73e-01 | 98.7% | 75.5% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 37.0 | 4.31e-01 | 83.6% | 86.3% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 23.0 | 3.56e-01 | 91.4% | 85.3% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 41.0 | 4.32e-01 | 71.1% | 88.5% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 25.0 | 3.55e-01 | 90.9% | 83.9% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 38.0 | 3.62e-01 | 77.6% | 60.0% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 39.0 | 3.74e-01 | 72.4% | 81.9% |
| 7zo9A01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.54 | 37.0 | 3.32e-01 | 94.8% | 49.5% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 38.0 | 3.59e-01 | 72.8% | 79.3% |
| 1v9dB00 | 1.20.58.2220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain | 0.52 | 49.0 | 4.32e-01 | 100.0% | 86.6% |
| 4im0A04 | 1.20.1270.420 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.51 | 38.0 | 3.80e-01 | 75.0% | 76.9% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.51 | 39.0 | 4.09e-01 | 90.1% | 84.9% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 37.0 | 3.50e-01 | 73.3% | 77.1% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1760269 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.84 | 43.0 | 6.07e-01 | 70.3% | 99.1% |
| 4026675 | 603.1.1.172 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF1617 | 0.82 | 42.0 | 5.91e-01 | 76.3% | 100.0% |
| 3282593 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.81 | 48.0 | 4.76e-01 | 86.2% | 56.7% |
| 5067572 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.80 | 38.0 | 5.62e-01 | 86.6% | 100.0% |
| 4985142 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.79 | 38.0 | 3.98e-01 | 70.3% | 49.8% |
| 3394455 | 3602.1.1.17 ↗ | alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › KIF21A_4th | 0.77 | 52.0 | 4.63e-01 | 74.1% | 50.2% |
| 4535653 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.72 | 37.0 | 3.85e-01 | 81.5% | 52.1% |
| 3583890 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.70 | 38.0 | 4.79e-01 | 87.9% | 84.8% |
| 3494933 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.67 | 47.0 | 4.10e-01 | 70.7% | 49.0% |
| 3639947 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.65 | 42.0 | 4.64e-01 | 87.9% | 80.0% |
| 3699731 | 109.4.1.1375 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_SYVN1_N | 0.64 | 32.0 | 3.08e-01 | 79.3% | 41.2% |
| 3758651 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.64 | 42.0 | 4.58e-01 | 75.4% | 78.9% |
| 5001630 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.61 | 35.0 | 4.03e-01 | 86.6% | 74.7% |
| 4991905 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.61 | 53.0 | 4.94e-01 | 91.8% | 83.9% |
| 4013285 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.60 | 46.0 | 4.55e-01 | 84.9% | 75.8% |
| 3491073 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.58 | 48.0 | 4.22e-01 | 85.3% | 80.6% |
| 4018104 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.57 | 41.0 | 3.81e-01 | 73.7% | 64.1% |
| 4549103 | 3755.4.1.54 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340 | 0.57 | 45.0 | 3.69e-01 | 80.2% | 82.4% |
| 3726222 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 37.0 | 3.74e-01 | 79.3% | 63.9% |
| 3168919 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.56 | 40.0 | 3.71e-01 | 72.4% | 77.1% |
| 5082020 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.55 | 42.0 | 3.60e-01 | 78.9% | 68.6% |
| 3779631 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.54 | 39.0 | 4.21e-01 | 100.0% | 85.5% |
| 3614118 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.52 | 38.0 | 2.85e-01 | 73.3% | 89.0% |
| 3599997 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.52 | 40.0 | 2.67e-01 | 79.7% | 92.5% |
| 3713380 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 42.0 | 4.02e-01 | 86.6% | 74.1% |
| 4033880 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.51 | 35.0 | 3.80e-01 | 91.4% | 81.0% |
| 3173337 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.50 | 42.0 | 3.79e-01 | 85.8% | 93.1% |
| 3250469 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.50 | 45.0 | 4.20e-01 | 96.1% | 77.5% |