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tegument_protein_UL37
Euk-VirColumbid_alphaherpesvirus_1
tegument_protein_UL37__YP_009352945__Columbid_alphaherpesvirus_1__93386
Identity
- Accession:
- YP_009352945 ↗
- Protein ID:
- tegument_protein_UL37
- Kingdom:
- euk
Quality
73.5
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Mardivirus›
Columbid_alphaherpesvirus_1
TaxID: 93386
Cluster
View cluster (7 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 598-740
Domain cluster:
rep: tegument_protein_UL37__YP_009137112__Human_alphaherpesvirus_1__10298__D597-729
D2
medium
residues 11-103
Domain cluster:
rep: tegument_protein_UL37__YP_009137189__Human_alphaherpesvirus_2__10310__D54-123_144-163
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03970.19 best | Herpes_UL37_1 | 79.5 | 3.40e-22 | 100.0% | 34.8% |
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 52.0 | 4.68e-01 | 75.3% | 75.4% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 47.0 | 5.45e-01 | 74.2% | 98.4% |
| 2pftA00 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.71 | 63.0 | 3.95e-01 | 100.0% | 21.6% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.69 | 49.0 | 4.78e-01 | 75.3% | 76.7% |
| 3k7xA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.68 | 60.0 | 4.09e-01 | 100.0% | 32.9% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 55.0 | 5.20e-01 | 91.4% | 88.4% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.66 | 58.0 | 4.42e-01 | 100.0% | 51.5% |
| 2pvqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 55.0 | 5.30e-01 | 91.4% | 88.7% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.65 | 56.0 | 4.79e-01 | 95.7% | 76.8% |
| 2fbnA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 52.0 | 4.49e-01 | 89.2% | 58.2% |
| 4d8mA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.65 | 57.0 | 4.36e-01 | 97.8% | 73.6% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.64 | 46.0 | 4.72e-01 | 75.3% | 84.3% |
| 7qpgW01 | 1.10.357.150 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.64 | 56.0 | 4.52e-01 | 100.0% | 84.2% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.63 | 55.0 | 4.57e-01 | 100.0% | 67.6% |
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 37.0 | 4.05e-01 | 86.0% | 69.6% |
| 4b7yD00 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.63 | 45.0 | 4.48e-01 | 75.3% | 96.9% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 45.0 | 3.88e-01 | 76.3% | 93.4% |
| 3fhnA01 | 6.10.280.210 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A | 0.62 | 45.0 | 3.65e-01 | 76.3% | 42.9% |
| 3zgzA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.62 | 49.0 | 3.98e-01 | 88.2% | 45.2% |
| 3n2oA03 | 1.20.58.930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 48.0 | 4.83e-01 | 87.1% | 89.6% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.61 | 43.0 | 4.10e-01 | 75.3% | 67.3% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.60 | 52.0 | 4.17e-01 | 100.0% | 64.4% |
| 3k3oA02 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 43.0 | 4.47e-01 | 76.3% | 91.7% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 42.0 | 4.36e-01 | 76.3% | 93.0% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.59 | 42.0 | 4.09e-01 | 75.3% | 68.0% |
| 4j8dD00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 43.0 | 3.66e-01 | 89.2% | 45.1% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 40.0 | 4.19e-01 | 72.0% | 84.7% |
| 2h7oA01 | 1.20.120.1330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain | 0.58 | 51.0 | 4.69e-01 | 98.9% | 78.9% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 51.0 | 4.34e-01 | 100.0% | 85.4% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.58 | 49.0 | 4.59e-01 | 95.7% | 75.9% |
| 1a17A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 40.0 | 3.41e-01 | 87.1% | 42.1% |
| 2kc7A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 41.0 | 4.09e-01 | 92.5% | 69.7% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 41.0 | 3.74e-01 | 77.4% | 100.0% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.56 | 47.0 | 4.64e-01 | 97.8% | 100.0% |
| 1ldjA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.55 | 45.0 | 4.20e-01 | 94.6% | 90.4% |
| 3urzA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 43.0 | 3.45e-01 | 87.1% | 47.5% |
| 1hh8A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 45.0 | 3.59e-01 | 91.4% | 45.3% |
| 2c0kB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 44.0 | 3.79e-01 | 90.3% | 84.6% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 45.0 | 3.99e-01 | 100.0% | 89.9% |
| 6cxtB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.51 | 41.0 | 3.91e-01 | 90.3% | 77.7% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.50 | 41.0 | 3.80e-01 | 90.3% | 93.4% |
ECOD (33)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2098130 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.95 | 83.0 | 5.64e-01 | 100.0% | 30.5% |
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.93 | 79.0 | 4.82e-01 | 100.0% | 17.2% |
| 4982242 | 109.2.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid | 0.74 | 60.0 | 3.69e-01 | 91.4% | 15.4% |
| 3474944 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 59.0 | 4.28e-01 | 92.5% | 36.7% |
| 3905991 | 109.4.1.160 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3384 | 0.70 | 54.0 | 4.03e-01 | 93.5% | 33.0% |
| 3586713 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.70 | 56.0 | 4.72e-01 | 91.4% | 51.6% |
| 3716269 | 109.4.1.5 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 | 0.69 | 53.0 | 3.83e-01 | 92.5% | 28.9% |
| 3704321 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.69 | 49.0 | 5.13e-01 | 75.3% | 83.5% |
| 4106991 | 109.4.1.1211 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Frtz | 0.68 | 54.0 | 4.55e-01 | 86.0% | 55.0% |
| 3648097 | 109.4.1.429 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec7-like_HDS | 0.68 | 59.0 | 4.60e-01 | 95.7% | 54.5% |
| 3400801 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.68 | 49.0 | 4.32e-01 | 75.3% | 62.2% |
| 5018508 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 55.0 | 5.54e-01 | 91.4% | 91.6% |
| 4998292 | 109.2.1.106 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › PF25840 | 0.66 | 55.0 | 4.03e-01 | 92.5% | 34.1% |
| 3398148 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 54.0 | 3.73e-01 | 92.5% | 27.1% |
| 1165026 | 5000.4.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › Endotoxin_N | 0.65 | 57.0 | 4.35e-01 | 97.8% | 72.9% |
| 3620006 | 109.4.1.142 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CSN8_PSD8_EIF3K | 0.64 | 52.0 | 3.88e-01 | 91.4% | 36.1% |
| 3391259 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.63 | 45.0 | 4.60e-01 | 75.3% | 87.8% |
| 3365651 | 109.4.1.163 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SYMPK_PTA1_N | 0.63 | 52.0 | 3.48e-01 | 92.5% | 22.8% |
| 4030331 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 54.0 | 4.06e-01 | 100.0% | 38.0% |
| 3840925 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.63 | 50.0 | 4.24e-01 | 93.5% | 50.3% |
| 4083920 | 140.1.1.0 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.63 | 51.0 | 4.04e-01 | 88.2% | 44.2% |
| 3813564 | 3711.1.1.36 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › NPH3 | 0.62 | 49.0 | 4.00e-01 | 87.1% | 46.7% |
| 3824535 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 51.0 | 4.74e-01 | 92.5% | 77.5% |
| 3414203 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 52.0 | 4.08e-01 | 95.7% | 45.4% |
| 3472980 | 109.4.1.262 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_C | 0.60 | 52.0 | 4.49e-01 | 100.0% | 94.2% |
| 3727368 | 609.1.1.0 ↗ | alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase | 0.60 | 45.0 | 3.87e-01 | 80.6% | 66.7% |
| 3893391 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.59 | 41.0 | 4.16e-01 | 75.3% | 73.3% |
| 3442441 | 604.16.1.0 ↗ | alpha bundles › Spectrin repeat-like › Hypothetical membrane protein Ta0354, soluble domain › Hypothetical membrane protein Ta0354, soluble domain | 0.59 | 42.0 | 4.25e-01 | 75.3% | 75.8% |
| 5045957 | 4156.1.1.0 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like | 0.58 | 43.0 | 3.51e-01 | 79.6% | 82.2% |
| 3925863 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 49.0 | 3.56e-01 | 97.8% | 31.6% |
| 436032 | 109.4.1.191 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7 | 0.56 | 44.0 | 3.47e-01 | 87.1% | 48.1% |
| 3963163 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.50 | 36.0 | 3.12e-01 | 76.3% | 68.4% |
| 4260430 | 191.1.1.18 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_14 | 0.50 | 42.0 | 3.68e-01 | 97.8% | 79.3% |
D3
medium
residues 104-216
Domain cluster:
rep: tegument_protein_UL37__YP_009176900__Testudinid_alphaherpesvirus_3__2560801__D149-260
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03970.19 best | Herpes_UL37_1 | 97.2 | 1.40e-27 | 100.0% | 41.9% |
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 54.0 | 4.57e-01 | 83.2% | 83.5% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 60.0 | 5.55e-01 | 100.0% | 88.7% |
| 5lbmA00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.66 | 47.0 | 5.26e-01 | 77.9% | 100.0% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 43.0 | 4.10e-01 | 100.0% | 58.5% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.63 | 57.0 | 5.68e-01 | 100.0% | 97.4% |
| 2pmsC00 | 6.10.140.920 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 44.0 | 4.52e-01 | 73.5% | 86.2% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.62 | 41.0 | 4.14e-01 | 86.7% | 66.1% |
| 4d0nB01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.62 | 55.0 | 4.34e-01 | 100.0% | 72.7% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 49.0 | 4.38e-01 | 85.0% | 64.3% |
| 1st6A02 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.61 | 54.0 | 4.26e-01 | 97.3% | 94.1% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.61 | 43.0 | 3.64e-01 | 72.6% | 76.5% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 48.0 | 4.98e-01 | 100.0% | 93.1% |
| 4wjg400 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.60 | 49.0 | 3.76e-01 | 88.5% | 73.2% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 47.0 | 4.46e-01 | 89.4% | 70.1% |
| 3owaA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 48.0 | 4.18e-01 | 86.7% | 60.8% |
| 4doyA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 47.0 | 4.04e-01 | 87.6% | 54.1% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 52.0 | 5.10e-01 | 100.0% | 92.6% |
| 2jswA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.58 | 51.0 | 4.37e-01 | 100.0% | 68.3% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.57 | 49.0 | 4.98e-01 | 93.8% | 97.4% |
| 6pmiF01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.57 | 27.0 | 3.16e-01 | 87.6% | 61.3% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.57 | 48.0 | 4.51e-01 | 91.2% | 77.1% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 47.0 | 4.37e-01 | 91.2% | 77.7% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 46.0 | 3.80e-01 | 90.3% | 78.5% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.56 | 49.0 | 4.17e-01 | 97.3% | 89.2% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.55 | 46.0 | 3.93e-01 | 91.2% | 83.7% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.55 | 44.0 | 4.45e-01 | 86.7% | 93.8% |
| 4ys0A02 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.54 | 33.0 | 2.90e-01 | 91.2% | 41.2% |
| 2onkC00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.53 | 41.0 | 3.17e-01 | 81.4% | 63.1% |
| 2c0uA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 47.0 | 4.19e-01 | 100.0% | 81.7% |
| 1t33A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 38.0 | 3.44e-01 | 90.3% | 54.4% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.52 | 43.0 | 3.83e-01 | 89.4% | 73.0% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 46.0 | 4.17e-01 | 99.1% | 90.4% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.52 | 42.0 | 3.55e-01 | 85.0% | 95.5% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 46.0 | 4.25e-01 | 100.0% | 90.7% |
| 5iduC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 46.0 | 4.15e-01 | 100.0% | 84.3% |
| 1x9fD00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 45.0 | 4.24e-01 | 97.3% | 90.0% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 46.0 | 4.29e-01 | 100.0% | 91.4% |
| 1binA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 46.0 | 4.27e-01 | 99.1% | 92.3% |
| 3vr4B04 | 1.10.1140.10 | Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 | 0.51 | 40.0 | 3.63e-01 | 83.2% | 90.1% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 46.0 | 4.33e-01 | 100.0% | 89.7% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 45.0 | 4.06e-01 | 100.0% | 89.9% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.50 | 40.0 | 3.65e-01 | 85.8% | 80.9% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2098130 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.89 | 85.0 | 6.18e-01 | 100.0% | 44.0% |
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.89 | 80.0 | 5.08e-01 | 100.0% | 22.2% |
| 3949980 | 4177.1.1.62 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › EspA_EspE | 0.73 | 58.0 | 5.00e-01 | 83.2% | 87.6% |
| 4505260 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.70 | 53.0 | 4.44e-01 | 85.0% | 47.6% |
| 4005041 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.68 | 59.0 | 5.75e-01 | 100.0% | 87.2% |
| 5078219 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.67 | 54.0 | 4.66e-01 | 86.7% | 65.7% |
| 3242888 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.67 | 61.0 | 5.74e-01 | 100.0% | 87.4% |
| 5009949 | 192.29.1.301 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF973 | 0.66 | 57.0 | 4.58e-01 | 92.9% | 61.9% |
| 3805445 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.66 | 59.0 | 5.16e-01 | 100.0% | 72.0% |
| 3450026 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.65 | 54.0 | 4.85e-01 | 100.0% | 63.8% |
| 3917447 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 59.0 | 5.48e-01 | 100.0% | 85.0% |
| 3802240 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.65 | 45.0 | 4.80e-01 | 91.2% | 81.0% |
| 4544758 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.64 | 50.0 | 5.07e-01 | 83.2% | 90.9% |
| 3607681 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.63 | 58.0 | 5.47e-01 | 100.0% | 95.6% |
| 3247041 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.63 | 55.0 | 5.19e-01 | 100.0% | 82.9% |
| 3979458 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.60 | 55.0 | 4.70e-01 | 100.0% | 94.9% |
| 4962302 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.58 | 45.0 | 3.44e-01 | 81.4% | 66.5% |
| 3716257 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.57 | 48.0 | 4.57e-01 | 91.2% | 81.5% |
| 3579981 | 632.11.1.14 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › TMEM107 | 0.57 | 42.0 | 4.44e-01 | 91.2% | 87.0% |
| 3826019 | 633.22.1.0 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) | 0.57 | 50.0 | 4.29e-01 | 100.0% | 65.8% |
| 3306743 | 192.29.1.101 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N | 0.57 | 47.0 | 4.44e-01 | 89.4% | 77.8% |
| 4553792 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.57 | 45.0 | 3.47e-01 | 85.0% | 52.2% |
| 3385045 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 48.0 | 4.59e-01 | 91.2% | 83.1% |
| 3889386 | 4177.2.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › IKBKB_SDD | 0.56 | 46.0 | 3.46e-01 | 89.4% | 63.2% |
| 4965940 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.56 | 40.0 | 3.68e-01 | 74.3% | 71.0% |
| 4262162 | 3882.1.1.1 ↗ | alpha bundles › Atg17 › Atg17 › Atg17 › ATG17_like | 0.53 | 43.0 | 2.94e-01 | 89.4% | 60.6% |
| 134292 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.53 | 47.0 | 4.14e-01 | 100.0% | 79.8% |
| 3285010 | 174.1.1.7 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4345 | 0.52 | 46.0 | 4.41e-01 | 96.5% | 100.0% |
D4
medium
residues 217-391
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03970.19 best | Herpes_UL37_1 | 56.7 | 3.20e-15 | 32.0% | 20.6% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vu2201 | 1.20.58.1070 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 32.0 | 3.31e-01 | 90.9% | 58.8% |
| 3zheA02 | 1.25.40.760 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 34.0 | 3.22e-01 | 90.3% | 55.1% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.89 | 75.0 | 5.24e-01 | 100.0% | 31.5% |
| 3230196 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 31.0 | 3.68e-01 | 85.7% | 67.5% |
| 3258491 | 109.4.1.765 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vac14_Fab1_bd | 0.51 | 30.0 | 3.04e-01 | 90.3% | 54.4% |
D5
medium
residues 745-898
Domain cluster:
rep: tegument_protein_UL37__YP_182366__Gallid_alphaherpesvirus_1__10386__D706-889
D6
medium
residues 899-978