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tegument_protein_UL37

Euk-Vir

Human_betaherpesvirus_7

tegument_protein_UL37__YP_073770__Human_betaherpesvirus_7__10372

Identity

Accession:
YP_073770 ↗
Protein ID:
tegument_protein_UL37
Kingdom:
euk

Quality

81.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_7

TaxID: 10372

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 649-697_712-852
PDB
Domain cluster: rep: tegument_protein_UL37__NP_612690__Panine_betaherpesvirus_2__188763__D711-904
D2 medium residues 1-79
PDB
Domain cluster: rep: tegument_protein_UL37__YP_004940219__Saimiriine_betaherpesvirus_4__1535247__D1-106
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04523.19 best Herpes_U30 30.3 1.70e-07 89.9% 7.5%
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ebbA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.69 56.0 3.89e-01 89.9% 29.5%
2ii2A04 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.68 55.0 5.51e-01 89.9% 97.5%
3nfqB02 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.66 54.0 4.89e-01 91.1% 76.9%
4ksaA02 1.20.140.90 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain 0.65 54.0 4.57e-01 93.7% 84.7%
1wjtA00 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.65 55.0 5.06e-01 94.9% 76.7%
4i1eA03 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.64 54.0 4.59e-01 97.5% 100.0%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 49.0 4.12e-01 86.1% 70.0%
3ubkB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 51.0 4.43e-01 91.1% 78.4%
4eadA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.62 49.0 4.49e-01 87.3% 82.2%
4agsB04 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 49.0 4.16e-01 91.1% 75.9%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.59 42.0 2.78e-01 74.7% 54.3%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.59 40.0 3.92e-01 70.9% 86.5%
5cwhA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.59 50.0 4.11e-01 97.5% 52.6%
2guzB00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.57 36.0 3.86e-01 100.0% 76.9%
3urzA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 42.0 3.24e-01 84.8% 35.1%
2dlaA01 1.20.930.50 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.55 46.0 3.83e-01 100.0% 71.2%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 39.0 2.76e-01 77.2% 29.3%
2kckA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 42.0 3.84e-01 87.3% 63.4%
1nigA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.54 36.0 3.08e-01 70.9% 95.2%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 38.0 3.64e-01 74.7% 97.8%
2uv8A04 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 46.0 2.83e-01 98.7% 50.4%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 32.0 3.41e-01 100.0% 66.2%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.53 41.0 3.79e-01 91.1% 81.6%
1dgfA03 1.20.1370.60 Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › 0.52 41.0 3.79e-01 94.9% 81.6%
1gnlA01 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 41.0 3.41e-01 86.1% 53.2%
4x54A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 43.0 3.27e-01 97.5% 96.7%
1sxjE03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.50 42.0 3.94e-01 92.4% 87.6%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3252586 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 52.0 4.71e-01 84.8% 58.2%
3648924 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 55.0 5.21e-01 94.9% 87.4%
3639334 109.4.1.1756 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30849 0.65 53.0 4.19e-01 91.1% 56.5%
3258591 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.63 53.0 5.24e-01 96.2% 91.8%
3248189 109.16.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › TROVE domain-like › TROVE domain-like 0.62 48.0 3.27e-01 87.3% 21.6%
3223016 611.3.1.0 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.61 51.0 5.00e-01 96.2% 87.1%
3803417 109.4.1.1260 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, PPR_long 0.61 51.0 3.06e-01 93.7% 12.2%
3996811 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.60 51.0 4.07e-01 96.2% 62.4%
3515056 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 48.0 3.83e-01 91.1% 64.6%
4985834 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.58 51.0 3.73e-01 100.0% 63.2%
3520607 109.27.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › BACK 0.54 43.0 4.10e-01 91.1% 95.8%
3569167 3164.1.1.5 ↗ few secondary structure elements › Zinc-binding domain in Junin virus envelope glycoprotein › Zinc-binding domain in Junin virus envelope glycoprotein › Zinc-binding domain in Junin virus envelope glycoprotein › ZSWIM1-3_helical 0.54 35.0 3.91e-01 70.9% 88.3%
3740128 4982.1.1.0 ↗ alpha arrays › KaiA/RbsU domain-like › KaiA/RbsU domain › KaiA/RbsU domain 0.53 44.0 4.16e-01 92.4% 86.3%
D3 medium residues 80-209
PDB
Domain cluster: rep: UL47__YP_009137485__Papio_ursinus_cytomegalovirus__1667587__D107-143_158-215
D4 medium residues 210-319
PDB
Domain cluster: rep: tegument_protein_UL37__YP_004940219__Saimiriine_betaherpesvirus_4__1535247__D207-302
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04523.19 best Herpes_U30 52.7 2.70e-14 100.0% 12.7%
D5 medium residues 320-474
PDB
Domain cluster: rep: JM123__YP_238426__Macaca_fuscata_rhadinovirus__272551__D339-466
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04523.19 best Herpes_U30 66.3 2.20e-18 98.1% 18.1%
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4flbA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 38.0 4.08e-01 93.5% 77.9%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 51.0 4.42e-01 96.1% 89.0%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.55 43.0 4.62e-01 91.0% 95.5%
2fphX01 3.30.1370.160 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.53 26.0 3.59e-01 82.6% 93.5%
4a64A01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.51 41.0 4.38e-01 90.3% 98.5%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 43.0 4.12e-01 92.9% 87.9%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1283715 3852.1.1.1 ↗ alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 0.79 63.0 4.38e-01 100.0% 27.0%
3700079 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.60 46.0 4.05e-01 80.0% 92.9%
3300114 109.4.1.14 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MyTH4 0.57 39.0 3.53e-01 89.7% 48.6%
3254024 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 42.0 4.15e-01 79.4% 81.2%
4405715 604.5.1.8 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_2 0.53 42.0 3.54e-01 82.6% 74.1%
3810540 3684.1.1.10 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 0.53 44.0 3.98e-01 87.7% 89.3%
3260300 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.51 43.0 4.07e-01 91.0% 85.9%
4025565 4250.1.1.1 ↗ alpha bundles › Duffy-binding-like domain, N-terminal subdomain › Duffy-binding-like domain, N-terminal subdomain › Duffy-binding-like domain, N-terminal subdomain › Duffy_binding 0.51 39.0 3.71e-01 80.0% 89.2%
3377464 3755.3.1.285 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A 0.50 37.0 3.74e-01 86.5% 75.0%
D6 medium residues 475-498_546-641
PDB
Domain cluster: rep: tegument_protein_UL37__YP_009253934__Macaca_nemestrina_herpesvirus_7__1846169__D552-645