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tegument_protein_UL37
Euk-VirHuman_betaherpesvirus_5
tegument_protein_UL37__YP_081505__Human_betaherpesvirus_5__10359
Identity
- Accession:
- YP_081505 ↗
- Protein ID:
- tegument_protein_UL37
- Kingdom:
- euk
Quality
78.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Human_betaherpesvirus_5
TaxID: 10359
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-146_174-205
Domain cluster:
rep: tegument_protein__YP_010087505__Phascolarctid_gammaherpesvirus_1__2249313__D1-176
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 118.4 | 3.90e-34 | 95.5% | 17.3% |
D2
medium
residues 206-326
Domain cluster:
rep: tegument_protein_UL37__YP_004940219__Saimiriine_betaherpesvirus_4__1535247__D207-302
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 100.8 | 8.20e-29 | 100.0% | 13.7% |
D3
medium
residues 327-436
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 101.2 | 6.10e-29 | 100.0% | 13.1% |
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ctwB00 | 1.10.8.930 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 | 0.66 | 46.0 | 4.51e-01 | 83.6% | 65.8% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 42.0 | 4.94e-01 | 79.1% | 98.7% |
| 2lt3A01 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.63 | 33.0 | 3.43e-01 | 75.5% | 53.0% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.63 | 44.0 | 4.89e-01 | 81.8% | 92.9% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 48.0 | 5.03e-01 | 80.0% | 98.0% |
| 1nafA02 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 46.0 | 5.14e-01 | 80.9% | 100.0% |
| 4ackB00 | 1.25.40.590 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU | 0.62 | 43.0 | 3.92e-01 | 72.7% | 85.0% |
| 4nt1A00 | 1.10.3520.10 | Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein | 0.60 | 43.0 | 3.60e-01 | 75.5% | 95.0% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 46.0 | 4.74e-01 | 80.0% | 97.1% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.60 | 47.0 | 4.76e-01 | 83.6% | 98.2% |
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.59 | 41.0 | 4.11e-01 | 97.3% | 69.0% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 40.0 | 4.09e-01 | 82.7% | 71.6% |
| 5cy5B00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.58 | 53.0 | 4.77e-01 | 100.0% | 77.2% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 37.0 | 4.31e-01 | 81.8% | 96.0% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 38.0 | 3.99e-01 | 80.0% | 76.3% |
| 1grlB01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.57 | 40.0 | 3.09e-01 | 71.8% | 78.3% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 4.49e-01 | 83.6% | 91.7% |
| 3c64A00 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 3.91e-01 | 81.8% | 91.4% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 43.0 | 4.42e-01 | 81.8% | 87.2% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.56 | 41.0 | 3.74e-01 | 83.6% | 57.8% |
| 4ceiA03 | 6.10.250.2380 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.56 | 39.0 | 3.89e-01 | 84.5% | 70.5% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.55 | 41.0 | 3.68e-01 | 83.6% | 56.3% |
| 1mhyG02 | 1.20.1280.30 | Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 | 0.55 | 35.0 | 4.12e-01 | 81.8% | 98.6% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 43.0 | 4.20e-01 | 83.6% | 76.7% |
| 3efzB00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.55 | 40.0 | 3.23e-01 | 77.3% | 68.4% |
| 2qzcA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.54 | 47.0 | 3.86e-01 | 98.2% | 74.2% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.53 | 46.0 | 4.12e-01 | 100.0% | 98.8% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.53 | 40.0 | 4.03e-01 | 79.1% | 92.9% |
| 1w36C06 | 1.10.10.990 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.52 | 31.0 | 3.75e-01 | 79.1% | 90.3% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 41.0 | 4.16e-01 | 83.6% | 96.3% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.52 | 37.0 | 4.08e-01 | 83.6% | 94.3% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 40.0 | 4.15e-01 | 84.5% | 96.2% |
| 1kt1A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 35.0 | 3.17e-01 | 100.0% | 48.1% |
| 2jswA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.50 | 41.0 | 3.50e-01 | 90.0% | 60.3% |
| 3vuqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 39.0 | 3.39e-01 | 83.6% | 70.5% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3801688 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 52.0 | 5.31e-01 | 84.5% | 96.2% |
| 3586228 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 51.0 | 5.30e-01 | 85.5% | 100.0% |
| 4046137 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.61 | 48.0 | 4.20e-01 | 83.6% | 70.1% |
| 3795 | 603.2.1.2 ↗ | alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil | 0.61 | 48.0 | 4.74e-01 | 84.5% | 93.2% |
| 3237761 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 47.0 | 4.92e-01 | 82.7% | 96.0% |
| 3941249 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 48.0 | 5.05e-01 | 84.5% | 99.0% |
| 3905848 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.60 | 47.0 | 4.28e-01 | 82.7% | 64.8% |
| 3221766 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 47.0 | 4.87e-01 | 84.5% | 91.4% |
| 3577230 | 604.1.1.5 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_3 | 0.59 | 47.0 | 4.87e-01 | 84.5% | 100.0% |
| 3224989 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.59 | 46.0 | 4.31e-01 | 83.6% | 75.7% |
| 3792010 | 604.1.1.105 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1_2 | 0.59 | 46.0 | 4.74e-01 | 82.7% | 89.5% |
| 3277234 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.59 | 46.0 | 3.90e-01 | 83.6% | 57.8% |
| 3254975 | 603.2.1.2 ↗ | alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil | 0.58 | 46.0 | 4.60e-01 | 83.6% | 87.8% |
| 143217 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 46.0 | 4.79e-01 | 83.6% | 93.9% |
| 3585432 | 604.1.1.98 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1 | 0.58 | 46.0 | 4.57e-01 | 84.5% | 87.8% |
| 4936312 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 45.0 | 4.53e-01 | 82.7% | 90.0% |
| 3269429 | 603.2.1.2 ↗ | alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil | 0.57 | 45.0 | 4.52e-01 | 84.5% | 95.7% |
| 3172910 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.57 | 43.0 | 4.40e-01 | 80.0% | 89.5% |
| 3576591 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.57 | 44.0 | 4.16e-01 | 83.6% | 80.7% |
| 4951650 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.56 | 51.0 | 3.85e-01 | 100.0% | 60.8% |
| 4020741 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.56 | 37.0 | 2.82e-01 | 92.7% | 29.4% |
| 3914665 | 604.5.1.10 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › HRG | 0.56 | 43.0 | 3.98e-01 | 82.7% | 72.9% |
| 3635930 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.56 | 43.0 | 3.87e-01 | 81.8% | 67.1% |
| 3935027 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 44.0 | 4.57e-01 | 84.5% | 95.0% |
| 4010905 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.55 | 42.0 | 4.04e-01 | 81.8% | 85.4% |
| 3174287 | 633.23.1.9 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › SUR7 | 0.55 | 43.0 | 3.66e-01 | 83.6% | 82.7% |
| 4015889 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.55 | 45.0 | 3.83e-01 | 100.0% | 52.1% |
| 4021006 | 627.1.1.0 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain | 0.55 | 45.0 | 3.82e-01 | 100.0% | 52.1% |
| 4027942 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 48.0 | 3.16e-01 | 100.0% | 27.2% |
| 3624507 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 43.0 | 4.26e-01 | 82.7% | 85.2% |
| 3177598 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.55 | 41.0 | 4.33e-01 | 80.9% | 91.9% |
| 3589790 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.54 | 47.0 | 3.76e-01 | 96.4% | 80.4% |
| 3723690 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.54 | 42.0 | 4.09e-01 | 83.6% | 82.4% |
| 3272245 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.54 | 47.0 | 3.58e-01 | 97.3% | 67.8% |
| 4014788 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 42.0 | 4.32e-01 | 82.7% | 100.0% |
| 3239878 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.54 | 39.0 | 4.25e-01 | 96.4% | 94.4% |
| 3714155 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 40.0 | 4.24e-01 | 83.6% | 92.6% |
| 3876261 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.53 | 45.0 | 3.90e-01 | 98.2% | 59.4% |
| 3989031 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.53 | 45.0 | 3.57e-01 | 97.3% | 74.4% |
| 3262083 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.52 | 40.0 | 4.07e-01 | 80.0% | 90.5% |
| 3503541 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.51 | 39.0 | 3.66e-01 | 81.8% | 69.3% |
| 3637933 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.51 | 43.0 | 3.18e-01 | 90.9% | 73.0% |
| 3928047 | 601.1.2.111 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DUF7087 | 0.51 | 41.0 | 3.89e-01 | 90.0% | 80.4% |
| 3899734 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.50 | 39.0 | 4.10e-01 | 82.7% | 98.0% |
| 3275892 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.50 | 45.0 | 3.95e-01 | 100.0% | 69.7% |
D4
medium
residues 557-724_948-971
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 125.9 | 2.10e-36 | 97.9% | 18.9% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vdyA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 28.0 | 3.22e-01 | 89.6% | 70.0% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.51 | 38.0 | 3.28e-01 | 76.6% | 87.8% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5006400 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 26.0 | 2.48e-01 | 70.8% | 32.2% |
| 3254479 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.57 | 31.0 | 3.39e-01 | 96.4% | 62.6% |
D5
medium
residues 725-875
Domain cluster:
rep: tegument_protein_UL37__NP_612690__Panine_betaherpesvirus_2__188763__D711-904
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 110.0 | 1.40e-31 | 100.0% | 17.9% |