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tegument_protein_UL37
Euk-VirGallid_alphaherpesvirus_1
tegument_protein_UL37__YP_182366__Gallid_alphaherpesvirus_1__10386
Identity
- Accession:
- YP_182366 ↗
- Protein ID:
- tegument_protein_UL37
- Kingdom:
- euk
Quality
64.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Iltovirus›
Gallid_alphaherpesvirus_1
TaxID: 10386
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 706-889
Domain cluster:
representative
CATH (46)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.84 | 47.0 | 6.27e-01 | 75.5% | 100.0% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 43.0 | 6.00e-01 | 80.4% | 100.0% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 43.0 | 6.00e-01 | 81.0% | 100.0% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.82 | 46.0 | 5.64e-01 | 86.4% | 85.6% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.81 | 58.0 | 6.12e-01 | 87.5% | 82.2% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.80 | 61.0 | 6.38e-01 | 87.0% | 85.1% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 53.0 | 6.34e-01 | 91.8% | 100.0% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.79 | 69.0 | 6.36e-01 | 90.2% | 83.4% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 58.0 | 5.33e-01 | 98.9% | 61.4% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.77 | 40.0 | 5.41e-01 | 84.8% | 97.8% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.77 | 48.0 | 5.82e-01 | 88.6% | 95.8% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 46.0 | 5.84e-01 | 85.3% | 100.0% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 40.0 | 4.37e-01 | 83.7% | 60.4% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 50.0 | 5.96e-01 | 92.9% | 96.8% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.75 | 55.0 | 5.50e-01 | 91.8% | 71.9% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.75 | 49.0 | 4.75e-01 | 91.8% | 59.5% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.75 | 32.0 | 4.90e-01 | 79.9% | 98.6% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.75 | 49.0 | 4.05e-01 | 70.7% | 39.2% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.74 | 47.0 | 4.68e-01 | 88.0% | 60.7% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 41.0 | 4.11e-01 | 91.3% | 52.2% |
| 3nyjA00 | 1.20.120.770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain | 0.74 | 48.0 | 4.86e-01 | 90.8% | 65.7% |
| 4k1pE00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.74 | 66.0 | 5.40e-01 | 95.1% | 79.7% |
| 4dyqA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.74 | 26.0 | 3.53e-01 | 76.1% | 58.3% |
| 7nmqA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.73 | 67.0 | 5.29e-01 | 95.7% | 83.1% |
| 1hciA03 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 47.0 | 5.69e-01 | 88.6% | 100.0% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 43.0 | 5.49e-01 | 77.7% | 100.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 61.0 | 6.29e-01 | 100.0% | 95.4% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.72 | 66.0 | 5.37e-01 | 98.4% | 75.2% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.71 | 50.0 | 5.80e-01 | 88.0% | 100.0% |
| 1ciiA01 | 1.20.250.10 | Mainly Alpha › Up-down Bundle › Colicin Ia; domain 1 › Colicin Ia, domain 1 | 0.70 | 54.0 | 4.27e-01 | 78.8% | 68.9% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.70 | 52.0 | 5.48e-01 | 94.0% | 85.4% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 37.0 | 4.87e-01 | 71.7% | 93.9% |
| 1qu7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.70 | 49.0 | 4.51e-01 | 70.7% | 59.9% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 48.0 | 5.03e-01 | 83.7% | 76.8% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 48.0 | 4.32e-01 | 75.0% | 52.3% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.67 | 59.0 | 4.98e-01 | 94.0% | 69.0% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.67 | 43.0 | 5.17e-01 | 84.2% | 99.1% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.67 | 36.0 | 4.58e-01 | 77.7% | 87.3% |
| 3rrkA02 | 1.20.1460.20 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › | 0.62 | 37.0 | 4.01e-01 | 71.2% | 68.4% |
| 7smtA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.60 | 42.0 | 4.31e-01 | 95.7% | 74.7% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.55 | 49.0 | 3.61e-01 | 94.6% | 55.9% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.54 | 24.0 | 3.35e-01 | 80.4% | 86.7% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 33.0 | 3.63e-01 | 79.3% | 76.0% |
| 7utzR02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 41.0 | 3.57e-01 | 81.0% | 74.7% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 34.0 | 3.66e-01 | 79.9% | 77.0% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 39.0 | 4.34e-01 | 85.3% | 100.0% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3806507 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.86 | 71.0 | 6.47e-01 | 95.7% | 66.8% |
| 3577620 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.83 | 52.0 | 6.52e-01 | 89.7% | 100.0% |
| 3494045 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.83 | 49.0 | 5.41e-01 | 87.5% | 71.3% |
| 3876247 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.83 | 54.0 | 6.60e-01 | 87.5% | 100.0% |
| 3276862 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.83 | 63.0 | 5.96e-01 | 95.1% | 66.5% |
| 4663621 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.83 | 58.0 | 6.82e-01 | 90.2% | 100.0% |
| 4977102 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.83 | 51.0 | 6.19e-01 | 73.9% | 91.2% |
| 3883667 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.82 | 47.0 | 6.20e-01 | 79.3% | 100.0% |
| 3855782 | 604.1.1.92 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_desmoplakin_3 | 0.82 | 49.0 | 6.03e-01 | 82.6% | 91.7% |
| 5047075 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 56.0 | 4.41e-01 | 70.1% | 65.9% |
| 3418792 | 3755.3.1.400 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A_C | 0.80 | 67.0 | 7.14e-01 | 92.4% | 99.4% |
| 4024356 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.79 | 66.0 | 7.07e-01 | 95.1% | 100.0% |
| 5083475 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.79 | 56.0 | 4.84e-01 | 93.5% | 48.4% |
| 4086306 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.78 | 55.0 | 5.04e-01 | 70.7% | 73.8% |
| 4400687 | 2004.1.1.782 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23, AAA_29, SbcC_Walker_B | 0.78 | 49.0 | 3.63e-01 | 71.7% | 26.4% |
| 3355282 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.78 | 66.0 | 6.59e-01 | 88.0% | 90.0% |
| 4955963 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 54.0 | 5.23e-01 | 70.1% | 84.5% |
| 3949412 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.78 | 54.0 | 5.40e-01 | 70.1% | 70.3% |
| 3569017 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.77 | 54.0 | 5.81e-01 | 97.8% | 82.5% |
| 3702347 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.77 | 51.0 | 5.21e-01 | 70.1% | 69.7% |
| 3789529 | 604.12.1.4 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 | 0.76 | 53.0 | 6.17e-01 | 86.4% | 100.0% |
| 5070736 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.75 | 51.0 | 4.94e-01 | 71.2% | 62.5% |
| 4345467 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.75 | 50.0 | 3.66e-01 | 71.2% | 27.0% |
| 4417464 | 3758.1.1.4 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › TelA | 0.75 | 68.0 | 5.99e-01 | 95.7% | 78.8% |
| 4991905 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.75 | 69.0 | 5.84e-01 | 97.8% | 75.4% |
| 3719591 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.75 | 66.0 | 6.22e-01 | 92.4% | 82.8% |
| 3770021 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.74 | 61.0 | 5.91e-01 | 93.5% | 77.1% |
| 4549103 | 3755.4.1.54 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340 | 0.74 | 52.0 | 3.99e-01 | 71.2% | 70.3% |
| 4937528 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.74 | 55.0 | 5.62e-01 | 75.5% | 82.9% |
| 3722750 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.74 | 65.0 | 5.34e-01 | 93.5% | 84.4% |
| 3711574 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.73 | 68.0 | 6.32e-01 | 100.0% | 84.3% |
| 3496957 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.72 | 52.0 | 3.56e-01 | 73.4% | 55.0% |
| 3394455 | 3602.1.1.17 ↗ | alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › KIF21A_4th | 0.71 | 61.0 | 5.07e-01 | 95.1% | 53.0% |
| 3579748 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.71 | 48.0 | 5.00e-01 | 71.2% | 74.1% |
| 3473984 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.70 | 59.0 | 5.25e-01 | 89.1% | 66.3% |
| 3697385 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.70 | 50.0 | 3.74e-01 | 72.8% | 74.2% |
| 3730963 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.69 | 65.0 | 4.81e-01 | 99.5% | 50.0% |
| 4013285 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.68 | 57.0 | 5.12e-01 | 89.7% | 66.7% |
| 3702282 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 50.0 | 5.62e-01 | 85.3% | 97.9% |
| 5066104 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.67 | 48.0 | 3.41e-01 | 73.4% | 54.4% |
| 5007101 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.66 | 46.0 | 3.64e-01 | 70.7% | 53.3% |
| 3477822 | 1147.1.1.1 ↗ | alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL | 0.64 | 41.0 | 4.84e-01 | 76.6% | 93.6% |
| 3714759 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.64 | 52.0 | 5.32e-01 | 83.2% | 90.3% |
| 3282593 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.63 | 55.0 | 5.00e-01 | 94.0% | 70.0% |
| 3993135 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 55.0 | 5.40e-01 | 93.5% | 90.3% |
| 3385727 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.62 | 49.0 | 4.25e-01 | 81.0% | 77.0% |
| 3928383 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.62 | 45.0 | 4.18e-01 | 87.0% | 59.1% |
| 3889450 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.61 | 48.0 | 4.71e-01 | 85.3% | 75.5% |
| 3955485 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.59 | 46.0 | 3.96e-01 | 97.8% | 51.0% |
| 3936511 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 50.0 | 3.72e-01 | 100.0% | 62.9% |
D2
medium
residues 38-129
Domain cluster:
representative
CATH (57)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.78 | 50.0 | 5.98e-01 | 78.3% | 95.2% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.73 | 61.0 | 5.66e-01 | 90.2% | 89.7% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.71 | 59.0 | 5.22e-01 | 90.2% | 87.2% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.67 | 56.0 | 4.89e-01 | 91.3% | 84.4% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.66 | 49.0 | 4.68e-01 | 90.2% | 67.9% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.66 | 45.0 | 3.61e-01 | 71.7% | 89.5% |
| 1grlB01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.65 | 50.0 | 3.72e-01 | 83.7% | 65.2% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 52.0 | 4.96e-01 | 90.2% | 83.3% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 47.0 | 5.12e-01 | 87.0% | 98.6% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.63 | 49.0 | 4.55e-01 | 90.2% | 66.7% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.62 | 39.0 | 4.09e-01 | 70.7% | 70.4% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.62 | 51.0 | 5.10e-01 | 92.4% | 93.8% |
| 1zoyA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.62 | 50.0 | 4.67e-01 | 90.2% | 69.2% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 43.0 | 4.10e-01 | 72.8% | 97.2% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.60 | 37.0 | 4.44e-01 | 70.7% | 93.4% |
| 2ptfB02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.60 | 37.0 | 4.38e-01 | 87.0% | 100.0% |
| 3fhnA01 | 6.10.280.210 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A | 0.60 | 48.0 | 3.92e-01 | 92.4% | 44.6% |
| 4aidA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.60 | 47.0 | 4.98e-01 | 85.9% | 97.6% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.60 | 43.0 | 3.85e-01 | 75.0% | 82.0% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.60 | 45.0 | 4.13e-01 | 83.7% | 98.5% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.60 | 47.0 | 4.88e-01 | 88.0% | 92.0% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.59 | 47.0 | 4.53e-01 | 87.0% | 91.7% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 41.0 | 4.13e-01 | 95.7% | 70.1% |
| 3ce2A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.59 | 50.0 | 4.27e-01 | 95.7% | 72.7% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 34.0 | 3.58e-01 | 89.1% | 63.4% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.58 | 44.0 | 4.08e-01 | 89.1% | 63.0% |
| 2rpaA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 44.0 | 4.66e-01 | 90.2% | 97.4% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 47.0 | 4.53e-01 | 92.4% | 84.4% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 46.0 | 4.06e-01 | 91.3% | 58.0% |
| 2qibB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 50.0 | 3.90e-01 | 100.0% | 68.3% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.56 | 47.0 | 4.04e-01 | 93.5% | 59.5% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 46.0 | 4.41e-01 | 89.1% | 85.2% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 45.0 | 4.08e-01 | 91.3% | 72.6% |
| 8a0rA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 48.0 | 4.31e-01 | 98.9% | 68.5% |
| 1qqeA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 41.0 | 3.04e-01 | 100.0% | 26.7% |
| 1hbgA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 48.0 | 4.08e-01 | 94.6% | 69.4% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.55 | 47.0 | 4.35e-01 | 98.9% | 74.1% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 42.0 | 3.62e-01 | 97.8% | 49.4% |
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.55 | 44.0 | 4.22e-01 | 91.3% | 73.6% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.55 | 44.0 | 4.31e-01 | 90.2% | 87.3% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 33.0 | 3.45e-01 | 89.1% | 63.2% |
| 2a9uA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 40.0 | 3.69e-01 | 97.8% | 57.9% |
| 3k1hA00 | 3.30.1120.180 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 | 0.54 | 42.0 | 3.95e-01 | 87.0% | 67.8% |
| 7qihA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 34.0 | 3.39e-01 | 98.9% | 58.4% |
| 2w0gA00 | 1.20.58.610 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain | 0.53 | 43.0 | 3.92e-01 | 90.2% | 79.1% |
| 2cwoA01 | 1.20.58.1200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RNA silencing suppressor P21, N-terminal domain | 0.53 | 40.0 | 4.29e-01 | 94.6% | 100.0% |
| 1j0mA01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.53 | 46.0 | 3.18e-01 | 100.0% | 26.3% |
| 6j3eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 45.0 | 3.91e-01 | 97.8% | 80.3% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 45.0 | 4.03e-01 | 96.7% | 91.1% |
| 2if4A02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 47.0 | 4.17e-01 | 100.0% | 68.4% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.53 | 43.0 | 4.37e-01 | 91.3% | 91.0% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.52 | 40.0 | 4.21e-01 | 92.4% | 90.6% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 46.0 | 3.87e-01 | 98.9% | 70.7% |
| 2b1eA01 | 1.20.58.1150 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 41.0 | 4.27e-01 | 91.3% | 94.2% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 42.0 | 3.73e-01 | 87.0% | 69.2% |
| 1htjF00 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.50 | 45.0 | 3.63e-01 | 100.0% | 86.8% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.50 | 41.0 | 3.60e-01 | 90.2% | 90.1% |
ECOD (59)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3598148 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.76 | 62.0 | 5.07e-01 | 87.0% | 55.2% |
| 3957116 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.75 | 65.0 | 4.94e-01 | 95.7% | 51.6% |
| 4959408 | 1075.1.1.38 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › FLQE3_permease | 0.72 | 62.0 | 4.68e-01 | 96.7% | 50.0% |
| 4886107 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.70 | 57.0 | 5.58e-01 | 90.2% | 81.0% |
| 4372227 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.70 | 61.0 | 5.49e-01 | 95.7% | 76.8% |
| 3572533 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 57.0 | 4.06e-01 | 90.2% | 34.2% |
| 4987734 | 4070.1.1.0 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like | 0.67 | 61.0 | 4.93e-01 | 100.0% | 74.7% |
| 4460528 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.66 | 52.0 | 5.20e-01 | 84.8% | 84.2% |
| 4172899 | 633.24.1.0 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain | 0.66 | 51.0 | 5.12e-01 | 83.7% | 87.4% |
| 5074624 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.64 | 51.0 | 4.59e-01 | 88.0% | 85.2% |
| 3285329 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.64 | 56.0 | 4.37e-01 | 100.0% | 45.1% |
| 5077373 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 54.0 | 5.34e-01 | 98.9% | 90.0% |
| 3778624 | 627.1.1.0 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain | 0.62 | 50.0 | 4.88e-01 | 87.0% | 81.0% |
| 3511626 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.62 | 52.0 | 4.25e-01 | 91.3% | 84.7% |
| 3390932 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 47.0 | 4.82e-01 | 90.2% | 85.6% |
| 3923922 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.62 | 41.0 | 4.41e-01 | 84.8% | 82.7% |
| 3950985 | 138.1.1.3 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNApol3-delta_C | 0.62 | 46.0 | 3.77e-01 | 78.3% | 92.9% |
| 5020412 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.60 | 48.0 | 4.68e-01 | 88.0% | 87.6% |
| 3232264 | 109.25.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN | 0.60 | 52.0 | 4.76e-01 | 100.0% | 80.0% |
| 3955636 | 604.12.1.106 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF28475 | 0.60 | 39.0 | 4.34e-01 | 73.9% | 82.7% |
| 3463676 | 109.4.1.1186 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF6857 | 0.59 | 52.0 | 4.44e-01 | 98.9% | 59.4% |
| 4995297 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.59 | 48.0 | 4.56e-01 | 92.4% | 81.7% |
| 5054354 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.59 | 49.0 | 4.16e-01 | 96.7% | 92.9% |
| 3282705 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.58 | 52.0 | 4.29e-01 | 100.0% | 61.2% |
| 3904719 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.58 | 48.0 | 3.74e-01 | 98.9% | 41.0% |
| 3497029 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.58 | 44.0 | 4.28e-01 | 91.3% | 73.0% |
| 3831265 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 44.0 | 4.42e-01 | 93.5% | 78.9% |
| 3393542 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.57 | 44.0 | 3.75e-01 | 92.4% | 49.0% |
| 3828970 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.57 | 46.0 | 4.64e-01 | 91.3% | 86.3% |
| 3724802 | 109.4.1.381 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rrn11 | 0.57 | 52.0 | 3.65e-01 | 100.0% | 46.8% |
| 3603670 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.57 | 47.0 | 3.66e-01 | 100.0% | 40.0% |
| 3631742 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.57 | 50.0 | 3.94e-01 | 97.8% | 86.1% |
| 3686751 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.57 | 42.0 | 4.48e-01 | 92.4% | 91.3% |
| 5072449 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.56 | 43.0 | 4.44e-01 | 90.2% | 83.3% |
| 3756 | 601.20.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipophorin-III › Apolipophorin-III | 0.56 | 47.0 | 4.04e-01 | 93.5% | 59.5% |
| 5018948 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.56 | 46.0 | 4.40e-01 | 92.4% | 83.6% |
| 4935676 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.56 | 46.0 | 4.43e-01 | 92.4% | 82.7% |
| 3584048 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 43.0 | 4.36e-01 | 92.4% | 85.6% |
| 3453526 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.56 | 42.0 | 3.88e-01 | 96.7% | 60.8% |
| 4978312 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.56 | 40.0 | 4.47e-01 | 88.0% | 98.6% |
| 3582234 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 45.0 | 4.46e-01 | 90.2% | 82.0% |
| 1503807 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.55 | 46.0 | 4.33e-01 | 93.5% | 80.0% |
| 5036565 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.55 | 48.0 | 3.80e-01 | 100.0% | 47.0% |
| 3263375 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.55 | 49.0 | 3.95e-01 | 100.0% | 51.1% |
| 3773235 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.55 | 41.0 | 4.18e-01 | 91.3% | 81.1% |
| 4940283 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.55 | 43.0 | 3.56e-01 | 98.9% | 44.6% |
| 4947260 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.55 | 43.0 | 4.59e-01 | 97.8% | 98.8% |
| 3975328 | 3718.1.1.1 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT | 0.54 | 43.0 | 4.47e-01 | 92.4% | 95.3% |
| 4979381 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.53 | 46.0 | 3.62e-01 | 98.9% | 43.1% |
| 3718498 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.53 | 44.0 | 4.47e-01 | 90.2% | 91.1% |
| 4049927 | 4044.1.1.1 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane | 0.53 | 36.0 | 3.65e-01 | 72.8% | 68.4% |
| 3480252 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.53 | 38.0 | 4.11e-01 | 93.5% | 96.0% |
| 1141909 | 3718.1.1.1 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT | 0.53 | 43.0 | 4.37e-01 | 91.3% | 91.0% |
| 3690309 | 604.13.1.0 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like | 0.52 | 43.0 | 3.93e-01 | 90.2% | 68.0% |
| 2492496 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.52 | 43.0 | 3.65e-01 | 94.6% | 86.8% |
| 3901994 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.51 | 43.0 | 3.82e-01 | 90.2% | 75.4% |
| 4958131 | 109.10.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin | 0.51 | 43.0 | 3.45e-01 | 97.8% | 45.4% |
| 5084074 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.51 | 42.0 | 3.36e-01 | 97.8% | 41.4% |
| 3784830 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 45.0 | 3.57e-01 | 100.0% | 63.6% |
D3
medium
residues 312-473
Domain cluster:
rep: tegument_protein_UL37__YP_068340__Suid_alphaherpesvirus_1__10345__D296-434
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3zheB02 | 1.20.190.60 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › | 0.61 | 46.0 | 4.47e-01 | 98.1% | 71.3% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 49.0 | 4.69e-01 | 87.0% | 99.5% |
| 1b0bA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 36.0 | 3.84e-01 | 92.6% | 70.2% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 35.0 | 4.27e-01 | 84.6% | 97.1% |
| 3b34A05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.56 | 51.0 | 4.05e-01 | 98.8% | 62.5% |
| 4qhpA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.56 | 51.0 | 4.03e-01 | 98.8% | 63.3% |
| 7ep1B01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.55 | 45.0 | 4.01e-01 | 98.8% | 59.1% |
| 7ep3A01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.55 | 46.0 | 4.07e-01 | 99.4% | 61.1% |
| 3a0oA02 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.55 | 46.0 | 3.59e-01 | 92.0% | 55.1% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.54 | 32.0 | 3.66e-01 | 83.3% | 77.3% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.54 | 38.0 | 4.14e-01 | 79.0% | 88.6% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 39.0 | 3.68e-01 | 75.3% | 76.8% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 35.0 | 3.92e-01 | 78.4% | 88.6% |
| 5d1rB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 41.0 | 3.66e-01 | 96.9% | 59.7% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.51 | 35.0 | 3.62e-01 | 71.0% | 73.2% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.51 | 40.0 | 4.22e-01 | 93.2% | 93.6% |
| 1e7pC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.51 | 41.0 | 3.59e-01 | 85.8% | 89.8% |
| 6vxcA01 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.51 | 45.0 | 2.94e-01 | 99.4% | 67.8% |
| 4mbsA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 38.0 | 3.08e-01 | 80.9% | 80.9% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.50 | 36.0 | 3.96e-01 | 75.3% | 93.0% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.86 | 72.0 | 4.94e-01 | 100.0% | 28.8% |
| 3789279 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 45.0 | 3.28e-01 | 77.8% | 69.2% |
| 3621566 | 109.4.1.87 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 | 0.58 | 53.0 | 3.48e-01 | 100.0% | 27.8% |
| None | — | 0.58 | 49.0 | 3.25e-01 | 93.2% | 29.9% | |
| 3267294 | 109.4.1.330 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BIG2_C | 0.56 | 49.0 | 4.20e-01 | 96.3% | 79.3% |
| 3207708 | 109.4.1.1982 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26523 | 0.56 | 48.0 | 4.60e-01 | 95.1% | 87.8% |
| 3793060 | 109.4.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 | 0.56 | 48.0 | 4.24e-01 | 94.4% | 72.1% |
| 3506732 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 41.0 | 3.77e-01 | 75.9% | 69.8% |
| 3952713 | 109.4.1.497 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EccD | 0.55 | 47.0 | 3.78e-01 | 99.4% | 47.3% |
| 3938613 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 48.0 | 2.98e-01 | 98.1% | 24.6% |
| 3725100 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 48.0 | 3.81e-01 | 98.8% | 57.3% |
| 3489305 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 48.0 | 3.55e-01 | 100.0% | 82.5% |
| 5046767 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.53 | 37.0 | 3.27e-01 | 71.0% | 58.0% |
| 3613994 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.53 | 38.0 | 3.68e-01 | 72.8% | 67.8% |
| 3240339 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.53 | 43.0 | 3.71e-01 | 85.2% | 76.7% |
| 3591412 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.53 | 38.0 | 3.68e-01 | 73.5% | 66.7% |
| 3727603 | 109.4.1.598 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mak10 | 0.52 | 44.0 | 3.88e-01 | 91.4% | 98.8% |
| 3934050 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 47.0 | 3.94e-01 | 100.0% | 64.7% |
| 3972478 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 34.0 | 3.85e-01 | 71.6% | 90.8% |
| 3472905 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.51 | 41.0 | 3.90e-01 | 86.4% | 75.4% |
| 3832686 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.50 | 39.0 | 3.73e-01 | 82.1% | 82.1% |
| 4525096 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.50 | 37.0 | 3.69e-01 | 75.9% | 87.3% |
D4
medium
residues 549-705