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tegument_protein_UL37
Euk-VirHuman_gammaherpesvirus_4
tegument_protein_UL37__YP_401653__Human_gammaherpesvirus_4__10376
Identity
- Accession:
- YP_401653 ↗
- Protein ID:
- tegument_protein_UL37
- Kingdom:
- euk
Quality
59.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Lymphocryptovirus›
human_gammaherpesvirus_4
TaxID: 10376
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 752-889_913-958
D2
medium
residues 25-191
Domain cluster:
rep: tegument_protein__YP_010087505__Phascolarctid_gammaherpesvirus_1__2249313__D1-176
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 162.3 | 2.20e-47 | 97.6% | 18.4% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5cwkA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 44.0 | 4.44e-01 | 78.4% | 74.4% |
| 4by6A01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 46.0 | 3.88e-01 | 86.2% | 75.5% |
| 4lctB00 | 1.25.40.570 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 48.0 | 3.80e-01 | 92.8% | 59.5% |
| 1t5oA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.54 | 37.0 | 3.95e-01 | 88.0% | 80.1% |
| 4udsA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 37.0 | 3.55e-01 | 94.0% | 64.2% |
| 7dvqK01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.51 | 42.0 | 4.20e-01 | 86.8% | 85.5% |
| 3efzB00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.51 | 38.0 | 3.51e-01 | 78.4% | 83.1% |
| 7c4sB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 39.0 | 3.28e-01 | 79.0% | 75.7% |
| 4eadA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.51 | 33.0 | 3.89e-01 | 86.2% | 100.0% |
| 2e1qC05 | 3.30.390.50 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain | 0.50 | 27.0 | 3.09e-01 | 80.2% | 68.6% |
| 5jjxA01 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.50 | 44.0 | 3.72e-01 | 98.2% | 66.0% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3235930 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 46.0 | 3.83e-01 | 86.8% | 83.5% |
| 3721874 | 109.4.1.75 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › IFRD | 0.57 | 51.0 | 3.96e-01 | 99.4% | 87.9% |
| 3996299 | 109.5.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › adenylylcyclase associated protein, CAP-N › adenylylcyclase associated protein, CAP-N › CAP_N | 0.57 | 36.0 | 3.91e-01 | 82.0% | 76.3% |
| 3612931 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 45.0 | 3.37e-01 | 92.2% | 77.6% |
| 3172167 | 604.6.1.2 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › ANTH | 0.52 | 36.0 | 3.77e-01 | 70.7% | 89.7% |
| 5028980 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.52 | 37.0 | 3.58e-01 | 74.3% | 77.5% |
| 3934042 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.52 | 44.0 | 4.24e-01 | 94.0% | 80.0% |
| 3248574 | 109.4.1.926 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FH3_FHOD1-3 | 0.51 | 42.0 | 3.61e-01 | 88.0% | 69.6% |
| 3169908 | 109.4.1.167 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rif1_N | 0.50 | 43.0 | 2.98e-01 | 93.4% | 31.7% |
D3
medium
residues 192-249
Domain cluster:
rep: BOLF1__YP_001129450__Human_herpesvirus_4_type_2__12509__D193-249
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 40.6 | 1.30e-10 | 100.0% | 5.6% |
D4
medium
residues 311-471_494-506
Domain cluster:
rep: JM123__YP_238426__Macaca_fuscata_rhadinovirus__272551__D339-466
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 202.4 | 1.60e-59 | 100.0% | 20.7% |
D5
medium
residues 602-675_709-751
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 104.0 | 8.60e-30 | 100.0% | 10.4% |
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tfkB00 | 1.20.120.650 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Colicin D | 0.67 | 47.0 | 5.32e-01 | 94.9% | 100.0% |
| 3dyjA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.66 | 55.0 | 4.87e-01 | 88.9% | 77.7% |
| 4ocqA01 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.66 | 49.0 | 3.83e-01 | 76.9% | 72.9% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.66 | 36.0 | 3.26e-01 | 90.6% | 38.5% |
| 1b68A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.66 | 55.0 | 5.21e-01 | 89.7% | 98.6% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.66 | 55.0 | 5.28e-01 | 89.7% | 86.4% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.66 | 52.0 | 4.34e-01 | 84.6% | 98.0% |
| 1yjgA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.65 | 56.0 | 5.04e-01 | 91.5% | 97.5% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 48.0 | 3.79e-01 | 76.9% | 77.3% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 54.0 | 5.23e-01 | 89.7% | 86.3% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 55.0 | 4.52e-01 | 90.6% | 54.6% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.65 | 53.0 | 5.39e-01 | 88.9% | 89.4% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 56.0 | 4.57e-01 | 94.9% | 75.8% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.64 | 55.0 | 5.32e-01 | 92.3% | 91.7% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.64 | 51.0 | 5.00e-01 | 88.0% | 78.9% |
| 5jfqB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.63 | 44.0 | 3.21e-01 | 70.9% | 31.4% |
| 4ciuA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 44.0 | 3.72e-01 | 70.9% | 84.4% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.63 | 51.0 | 4.58e-01 | 88.9% | 73.8% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 51.0 | 4.90e-01 | 88.9% | 97.8% |
| 5l0wB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 45.0 | 4.22e-01 | 74.4% | 84.1% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.61 | 49.0 | 4.07e-01 | 88.9% | 64.5% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 49.0 | 4.91e-01 | 88.9% | 95.0% |
| 3u5nA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.60 | 44.0 | 4.41e-01 | 88.9% | 75.0% |
| 4jvsA01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 45.0 | 4.44e-01 | 80.3% | 91.3% |
| 6qumA04 | 1.10.1140.10 | Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 | 0.58 | 42.0 | 3.92e-01 | 75.2% | 59.1% |
| 2ptqA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.58 | 47.0 | 3.61e-01 | 88.0% | 78.8% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 40.0 | 4.70e-01 | 85.5% | 100.0% |
| 5eroA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.57 | 52.0 | 3.84e-01 | 99.1% | 91.0% |
| 6l3tA01 | 1.20.1440.80 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain | 0.57 | 47.0 | 3.92e-01 | 88.0% | 89.4% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.56 | 41.0 | 3.94e-01 | 76.9% | 83.1% |
| 4dhiB02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.55 | 46.0 | 4.29e-01 | 89.7% | 89.7% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.55 | 39.0 | 4.15e-01 | 74.4% | 89.4% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.55 | 46.0 | 4.17e-01 | 93.2% | 97.5% |
| 2f2gA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.55 | 45.0 | 3.75e-01 | 89.7% | 89.8% |
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.54 | 34.0 | 3.26e-01 | 91.5% | 53.3% |
| 2hg4D03 | 3.40.366.10 | Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 | 0.53 | 41.0 | 3.10e-01 | 82.9% | 63.2% |
| 2qkwA00 | 1.20.1270.140 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AvrPto | 0.53 | 38.0 | 4.12e-01 | 77.8% | 87.1% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 42.0 | 4.11e-01 | 85.5% | 94.6% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 43.0 | 4.24e-01 | 86.3% | 92.6% |
| 2z4vA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.52 | 47.0 | 3.48e-01 | 100.0% | 81.5% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.52 | 42.0 | 4.24e-01 | 100.0% | 85.5% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 35.0 | 3.73e-01 | 95.7% | 77.7% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.51 | 39.0 | 3.93e-01 | 83.8% | 97.4% |
| 4fp4A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.50 | 43.0 | 3.47e-01 | 95.7% | 70.0% |
ECOD (55)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3993967 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.75 | 54.0 | 5.12e-01 | 73.5% | 71.1% |
| 4979051 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.74 | 62.0 | 5.45e-01 | 89.7% | 74.7% |
| 3260332 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.71 | 64.0 | 5.69e-01 | 100.0% | 87.6% |
| 4929148 | 192.29.1.300 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › AmoC | 0.70 | 60.0 | 5.36e-01 | 91.5% | 90.0% |
| 2878134 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.69 | 57.0 | 5.43e-01 | 88.9% | 92.9% |
| 4928072 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.69 | 55.0 | 5.57e-01 | 83.8% | 100.0% |
| 3600308 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 56.0 | 4.50e-01 | 90.6% | 85.8% |
| 3283510 | 192.29.1.52 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy | 0.68 | 56.0 | 5.06e-01 | 88.0% | 97.4% |
| 4164765 | 601.1.3.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 | 0.67 | 52.0 | 4.59e-01 | 81.2% | 74.1% |
| 3195851 | 601.1.3.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 | 0.67 | 55.0 | 4.82e-01 | 87.2% | 72.9% |
| 3496944 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.66 | 54.0 | 5.24e-01 | 86.3% | 90.8% |
| 4929492 | 601.1.3.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 | 0.66 | 56.0 | 5.28e-01 | 91.5% | 94.3% |
| 3377749 | 3843.1.1.15 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › ETR1_N | 0.65 | 47.0 | 5.01e-01 | 75.2% | 90.0% |
| 3971056 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.65 | 51.0 | 5.10e-01 | 83.8% | 89.2% |
| 3517672 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.64 | 53.0 | 4.91e-01 | 88.9% | 76.0% |
| 3668496 | 632.1.1.17 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Sas10_Utp3 | 0.63 | 45.0 | 4.83e-01 | 73.5% | 88.0% |
| 145714 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.63 | 51.0 | 4.64e-01 | 88.9% | 76.5% |
| 3804223 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.63 | 51.0 | 4.58e-01 | 88.0% | 85.5% |
| 3233827 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.63 | 51.0 | 5.14e-01 | 88.0% | 89.2% |
| 3734743 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.63 | 45.0 | 3.50e-01 | 74.4% | 69.6% |
| 3474226 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 49.0 | 4.69e-01 | 85.5% | 88.6% |
| 3786110 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.62 | 56.0 | 4.52e-01 | 100.0% | 96.0% |
| 3211383 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.61 | 44.0 | 4.77e-01 | 80.3% | 86.0% |
| 3467780 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.61 | 44.0 | 4.09e-01 | 75.2% | 78.0% |
| 3659493 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.61 | 51.0 | 4.81e-01 | 89.7% | 82.7% |
| 3797268 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.61 | 49.0 | 4.52e-01 | 87.2% | 81.3% |
| 4001485 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.60 | 51.0 | 4.86e-01 | 92.3% | 84.3% |
| 3199446 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.60 | 48.0 | 5.11e-01 | 88.9% | 100.0% |
| 5047040 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.60 | 48.0 | 3.97e-01 | 85.5% | 84.8% |
| 3213000 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.60 | 43.0 | 3.48e-01 | 72.6% | 81.4% |
| 3277855 | 3562.1.1.3 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › DUF6328 | 0.60 | 47.0 | 4.41e-01 | 84.6% | 85.5% |
| 4119718 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.59 | 41.0 | 4.67e-01 | 85.5% | 93.3% |
| 3243052 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.59 | 54.0 | 4.10e-01 | 100.0% | 57.0% |
| 3651030 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.59 | 49.0 | 4.28e-01 | 89.7% | 80.0% |
| 3514002 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 52.0 | 4.82e-01 | 94.9% | 93.8% |
| 3589614 | 601.1.2.99 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar | 0.58 | 43.0 | 4.25e-01 | 76.1% | 82.1% |
| 3419359 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.58 | 47.0 | 4.51e-01 | 86.3% | 84.4% |
| 3880919 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.58 | 47.0 | 4.38e-01 | 87.2% | 86.5% |
| 5009776 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.57 | 45.0 | 4.77e-01 | 95.7% | 95.2% |
| 5038871 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.56 | 39.0 | 4.09e-01 | 78.6% | 79.0% |
| 5047771 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.56 | 44.0 | 4.46e-01 | 85.5% | 98.3% |
| 5052249 | 632.1.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › AmyA-A_glucT_m | 0.56 | 43.0 | 4.51e-01 | 87.2% | 87.3% |
| 3806117 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.55 | 46.0 | 4.20e-01 | 90.6% | 85.8% |
| 3799978 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.55 | 44.0 | 4.19e-01 | 86.3% | 82.1% |
| 3199926 | 611.2.1.0 ↗ | alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) | 0.53 | 38.0 | 3.75e-01 | 80.3% | 68.0% |
| 3469086 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.52 | 45.0 | 4.26e-01 | 91.5% | 99.3% |
| 4013663 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.52 | 44.0 | 4.03e-01 | 92.3% | 92.9% |
| 3440148 | 611.7.1.2 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MCAfunc | 0.52 | 42.0 | 3.98e-01 | 83.8% | 80.0% |
| 3764834 | 601.1.2.2 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ | 0.52 | 47.0 | 4.02e-01 | 100.0% | 86.3% |
| 3359287 | 611.7.1.14 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7792 | 0.52 | 44.0 | 3.92e-01 | 91.5% | 76.4% |
| 3936334 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.52 | 46.0 | 3.73e-01 | 99.1% | 85.7% |
| 3736801 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.52 | 47.0 | 4.17e-01 | 100.0% | 85.5% |
| 3391070 | 632.1.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid | 0.51 | 40.0 | 4.19e-01 | 84.6% | 87.3% |
| 3598146 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.51 | 38.0 | 4.05e-01 | 76.9% | 96.0% |
| 3335015 | 109.4.1.1169 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_ESP1_2nd | 0.50 | 45.0 | 3.50e-01 | 99.1% | 72.2% |