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tegument_protein_VP11_12

Euk-Vir

Meleagrid_alphaherpesvirus_1

tegument_protein_VP11_12__NP_073340__Meleagrid_alphaherpesvirus_1__37108

Identity

Accession:
NP_073340 ↗
Protein ID:
tegument_protein_VP11_12
Kingdom:
euk

Quality

70.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 14-124_141-163
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03387.19 best Herpes_UL46 88.3 6.60e-25 100.0% 34.0%
D2 medium residues 125-140_164-265
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03387.19 best Herpes_UL46 54.0 1.80e-14 87.3% 22.8%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 60.0 5.26e-01 79.7% 76.9%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 58.0 4.92e-01 79.7% 58.4%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.74 56.0 4.59e-01 78.8% 56.0%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.72 53.0 5.80e-01 78.0% 100.0%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.70 50.0 5.45e-01 74.6% 95.9%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.69 52.0 5.01e-01 79.7% 80.0%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 51.0 5.55e-01 79.7% 96.9%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.68 50.0 4.27e-01 78.0% 57.9%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 48.0 5.12e-01 74.6% 98.1%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 54.0 5.09e-01 86.4% 72.0%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 50.0 5.19e-01 79.7% 99.1%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.66 49.0 4.41e-01 78.0% 64.5%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.64 48.0 4.80e-01 79.7% 77.3%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.63 53.0 5.40e-01 92.4% 100.0%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.63 50.0 5.11e-01 86.4% 87.6%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.63 52.0 3.87e-01 91.5% 98.5%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.63 47.0 4.38e-01 78.8% 93.2%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.62 43.0 4.83e-01 77.1% 95.5%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.61 50.0 4.28e-01 86.4% 55.4%
4ielA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 43.0 4.42e-01 76.3% 76.7%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.60 48.0 4.16e-01 86.4% 62.6%
7e4mA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.60 45.0 3.49e-01 78.8% 88.7%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.60 40.0 4.47e-01 70.3% 93.1%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.56 42.0 3.36e-01 80.5% 90.2%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 41.0 3.78e-01 78.0% 75.3%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.56 30.0 3.35e-01 90.7% 65.6%
2cvzA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.55 41.0 4.03e-01 78.8% 97.0%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.54 44.0 4.22e-01 86.4% 78.2%
2cfqA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 42.0 3.49e-01 83.1% 78.5%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 35.0 4.14e-01 79.7% 100.0%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.53 37.0 4.21e-01 77.1% 93.5%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 44.0 3.70e-01 96.6% 95.0%
7b7tA01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.51 39.0 3.51e-01 79.7% 99.4%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.51 40.0 4.21e-01 85.6% 100.0%
3mk7A00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.50 44.0 3.02e-01 100.0% 77.9%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3552989 604.8.1.1 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Smac_DIABLO 0.81 62.0 5.25e-01 79.7% 72.3%
3715005 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.76 56.0 5.03e-01 77.1% 98.8%
3933045 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 57.0 4.84e-01 79.7% 63.0%
3814336 603.2.1.13 alpha bundles › STAT-like › STAT › STAT › NET2A_C 0.71 54.0 4.93e-01 79.7% 91.6%
5083776 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 52.0 5.70e-01 77.1% 97.9%
3502658 603.1.1.100 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.71 54.0 5.01e-01 79.7% 86.9%
3605285 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 57.0 5.35e-01 86.4% 92.4%
3231329 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.70 57.0 4.96e-01 86.4% 71.9%
3839889 601.51.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin 0.68 45.0 4.21e-01 78.0% 54.5%
4526671 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.68 51.0 3.99e-01 78.8% 60.0%
5005480 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 51.0 4.47e-01 79.7% 84.6%
3517330 603.2.1.1 alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.66 48.0 3.96e-01 74.6% 81.4%
4978688 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.66 49.0 5.40e-01 78.0% 96.8%
3579590 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.65 47.0 4.45e-01 74.6% 100.0%
3714007 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 51.0 3.12e-01 85.6% 44.4%
3871065 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 48.0 4.85e-01 81.4% 100.0%
3272619 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.63 47.0 4.69e-01 78.8% 80.0%
3894567 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.60 46.0 3.96e-01 81.4% 76.8%
4945548 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.59 47.0 4.02e-01 86.4% 86.2%
3791628 1203.1.2.0 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.58 51.0 4.81e-01 96.6% 99.3%
3406893 150.1.1.24 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Prominin 0.58 49.0 3.85e-01 93.2% 98.9%
3853566 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.56 42.0 4.26e-01 78.8% 83.5%
4554168 1079.1.1.13 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Mntp 0.55 39.0 3.46e-01 73.7% 80.0%
3395695 4177.2.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain 0.55 42.0 3.00e-01 79.7% 56.9%
4659183 1079.1.1.13 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Mntp 0.55 39.0 3.61e-01 73.7% 77.3%
3500007 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.53 43.0 3.93e-01 89.8% 100.0%
4946671 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 42.0 3.48e-01 86.4% 81.9%
3768459 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.51 44.0 3.83e-01 94.9% 90.3%
3880841 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.51 44.0 3.86e-01 94.9% 92.8%
3970466 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 43.0 3.67e-01 96.6% 90.5%
5070330 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.51 42.0 3.48e-01 92.4% 83.0%
D3 medium residues 266-384
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03387.19 best Herpes_UL46 105.1 5.50e-30 85.7% 19.5%
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.70 36.0 4.20e-01 94.1% 67.8%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.68 42.0 4.46e-01 95.8% 68.9%
3cbuA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 43.0 4.18e-01 100.0% 61.9%
4abnA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 46.0 3.55e-01 79.0% 90.7%
6srbA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 45.0 4.70e-01 95.8% 84.4%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.58 41.0 3.52e-01 100.0% 46.2%
5djsA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 31.0 2.92e-01 92.4% 41.3%
4ie5A02 1.20.58.1470 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FTO C-terminal domain 0.56 44.0 4.24e-01 83.2% 78.4%
4agsA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 43.0 4.13e-01 94.1% 71.1%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 48.0 3.86e-01 97.5% 76.5%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 44.0 3.85e-01 88.2% 82.6%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.54 40.0 4.43e-01 89.9% 95.8%
6al9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.54 34.0 3.72e-01 77.3% 81.3%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 38.0 3.77e-01 94.1% 70.5%
1to9A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.53 40.0 3.27e-01 79.8% 73.3%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.53 41.0 3.98e-01 81.5% 94.7%
3k8pC01 1.20.58.1440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 41.0 4.38e-01 97.5% 97.1%
3rvyA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.50 40.0 4.08e-01 91.6% 86.8%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.50 37.0 3.93e-01 90.8% 88.6%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3971056 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.70 44.0 4.45e-01 100.0% 62.5%
4622027 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.66 53.0 4.12e-01 85.7% 66.9%
3915982 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.60 42.0 4.20e-01 73.1% 88.8%
5062167 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.60 47.0 3.94e-01 85.7% 65.1%
3436931 192.6.1.11 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › eIF-3c_N 0.59 42.0 4.41e-01 92.4% 80.0%
3680600 604.12.1.67 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › eIF-3c_N 0.59 42.0 4.43e-01 93.3% 80.9%
3786830 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.59 47.0 3.88e-01 86.6% 79.1%
3497466 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.58 40.0 4.56e-01 92.4% 94.4%
3451070 226.1.1.3 a+b two layers › POZ domain › POZ domain › POZ domain › Skp1,Skp1_POZ 0.54 34.0 3.30e-01 92.4% 52.9%
3849992 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.54 40.0 4.37e-01 92.4% 93.0%
3504312 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.54 40.0 4.38e-01 92.4% 93.0%
3235672 192.29.1.137 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Otopetrin 0.53 42.0 3.63e-01 87.4% 89.3%
3705964 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 40.0 4.29e-01 78.2% 94.0%
3885645 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.53 43.0 3.71e-01 87.4% 62.2%
3695642 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.53 31.0 3.30e-01 90.8% 65.7%
3616343 601.1.1.97 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DNA_repr_REX1B 0.52 42.0 4.08e-01 86.6% 93.3%
3626951 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.51 34.0 3.14e-01 94.1% 52.7%
3590184 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.51 44.0 4.26e-01 96.6% 89.6%
3567398 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 44.0 3.65e-01 100.0% 58.3%