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tegument_protein_VP11_12

Euk-Vir

Cercopithecine_alphaherpesvirus_2

tegument_protein_VP11_12__YP_164489__Cercopithecine_alphaherpesvirus_2__10317

Identity

Accession:
YP_164489 ↗
Protein ID:
tegument_protein_VP11_12
Kingdom:
euk

Quality

69.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 172-221_290-325
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03387.19 best Herpes_UL46 71.2 1.10e-19 60.5% 11.7%
CATH (77)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3rklA00 6.10.140.1640 Special › Helix non-globular › Helix Hairpins › 0.81 53.0 5.56e-01 82.6% 72.5%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 57.0 6.54e-01 80.2% 100.0%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.77 55.0 6.30e-01 80.2% 100.0%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.77 61.0 5.50e-01 86.0% 63.2%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.77 62.0 6.01e-01 84.9% 97.9%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 53.0 5.87e-01 82.6% 91.2%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.75 56.0 5.95e-01 79.1% 95.9%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.75 59.0 6.41e-01 82.6% 98.6%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 62.0 4.60e-01 89.5% 75.6%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.74 54.0 5.43e-01 89.5% 76.5%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.74 61.0 5.72e-01 87.2% 79.4%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.74 58.0 4.80e-01 81.4% 51.4%
4gczA03 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.73 53.0 5.98e-01 86.0% 100.0%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.73 58.0 5.50e-01 84.9% 79.0%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 60.0 4.76e-01 86.0% 60.4%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.73 55.0 4.56e-01 81.4% 47.6%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.73 53.0 5.77e-01 75.6% 93.2%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.72 56.0 5.66e-01 86.0% 81.4%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.72 58.0 4.63e-01 84.9% 76.4%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.72 58.0 4.17e-01 84.9% 52.9%
3rx6A00 1.20.58.1090 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer 0.72 64.0 4.85e-01 95.3% 80.7%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.71 56.0 5.22e-01 84.9% 70.9%
3teqB00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 62.0 5.86e-01 94.2% 93.1%
2a3qA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.71 52.0 4.69e-01 75.6% 57.5%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.71 54.0 5.77e-01 81.4% 100.0%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.71 58.0 5.74e-01 86.0% 95.5%
6vq6G02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.71 59.0 4.59e-01 90.7% 86.4%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 53.0 5.59e-01 89.5% 89.5%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.71 61.0 5.53e-01 91.9% 94.6%
2etnB01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.71 54.0 5.67e-01 84.9% 90.8%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.71 56.0 3.72e-01 83.7% 79.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 58.0 6.02e-01 87.2% 92.6%
2yayA02 1.20.1670.10 Mainly Alpha › Up-down Bundle › all-alpha NTP pyrophosphatase › Type II deoxyuridine triphosphatase 0.70 53.0 4.52e-01 88.4% 51.1%
2gtaA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.69 48.0 4.65e-01 75.6% 63.9%
2wauA02 1.20.58.830 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 57.0 5.11e-01 95.3% 63.9%
2b3tB01 6.10.140.1980 Special › Helix non-globular › Helix Hairpins › 0.69 38.0 4.33e-01 89.5% 72.3%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.68 54.0 5.64e-01 86.0% 97.4%
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 46.0 4.93e-01 82.6% 82.4%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.68 58.0 4.52e-01 94.2% 84.2%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.67 58.0 5.22e-01 95.3% 73.1%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.67 53.0 5.34e-01 82.6% 87.1%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.67 49.0 5.37e-01 80.2% 100.0%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 51.0 4.27e-01 80.2% 61.5%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.67 55.0 5.13e-01 89.5% 96.2%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 54.0 3.89e-01 90.7% 69.3%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 56.0 5.22e-01 95.3% 74.8%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 48.0 5.29e-01 81.4% 97.1%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 51.0 4.68e-01 81.4% 64.0%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.66 52.0 4.68e-01 84.9% 66.4%
3fb2A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 56.0 5.28e-01 95.3% 79.0%
3cqcA00 1.20.190.50 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 0.66 59.0 4.23e-01 100.0% 58.3%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 56.0 5.26e-01 94.2% 79.8%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 55.0 5.25e-01 90.7% 80.8%
3udcA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 49.0 4.48e-01 80.2% 64.3%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 55.0 5.03e-01 95.3% 79.5%
1ykhA00 6.10.140.200 Special › Helix non-globular › Helix Hairpins › 0.65 49.0 4.75e-01 79.1% 72.6%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 56.0 5.24e-01 95.3% 87.9%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.65 50.0 5.01e-01 84.9% 80.0%
5fj8A06 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.64 49.0 4.06e-01 80.2% 47.6%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 54.0 5.17e-01 94.2% 79.4%
4hteA02 1.20.58.1740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 54.0 4.87e-01 90.7% 79.5%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 53.0 4.92e-01 93.0% 76.1%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 49.0 5.10e-01 83.7% 91.0%
4fxxB01 6.10.140.1790 Special › Helix non-globular › Helix Hairpins › 0.63 49.0 5.31e-01 100.0% 95.8%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 54.0 4.85e-01 95.3% 75.0%
4aybA07 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.63 48.0 4.27e-01 80.2% 59.2%
3terA00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 55.0 4.98e-01 98.8% 94.1%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.63 46.0 4.48e-01 77.9% 77.3%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 53.0 4.91e-01 93.0% 74.1%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 44.0 4.13e-01 91.9% 60.0%
1dtoA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.60 44.0 4.16e-01 76.7% 64.7%
1hx8A02 1.20.58.150 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › ANTH domain 0.59 47.0 4.28e-01 91.9% 64.1%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 46.0 4.24e-01 100.0% 64.9%
5jazA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.56 33.0 3.28e-01 86.0% 53.8%
8h6qD01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.55 50.0 3.40e-01 100.0% 73.6%
5fhiA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 48.0 4.15e-01 100.0% 84.9%
3c8eA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 47.0 3.88e-01 100.0% 74.5%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5040454 3922.1.1.137 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › HisKA 0.80 54.0 6.18e-01 86.0% 92.3%
3244499 109.4.1.2361 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › LIN9_C 0.77 64.0 6.34e-01 87.2% 88.9%
3619443 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.76 62.0 5.32e-01 86.0% 59.2%
4520297 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.76 62.0 4.34e-01 86.0% 31.4%
4149566 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.75 63.0 4.34e-01 87.2% 89.2%
4114693 5041.1.1.28 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › PF26135 0.75 58.0 6.37e-01 81.4% 100.0%
3973966 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.75 53.0 4.97e-01 72.1% 69.0%
3598431 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.75 62.0 4.83e-01 86.0% 46.7%
3812652 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.75 62.0 4.64e-01 87.2% 68.7%
5054541 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.74 61.0 3.61e-01 86.0% 14.0%
3706526 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 61.0 4.93e-01 86.0% 51.3%
4106453 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 60.0 5.57e-01 84.9% 69.5%
3937465 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.73 59.0 4.31e-01 87.2% 34.0%
3882066 3291.1.1.124 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Bap31 0.73 60.0 4.68e-01 84.9% 44.2%
4177674 4992.1.1.23 extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N 0.73 63.0 5.79e-01 93.0% 91.8%
3244102 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.73 62.0 5.68e-01 90.7% 97.3%
3597047 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.73 65.0 4.48e-01 95.3% 35.5%
3503307 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.72 67.0 5.37e-01 100.0% 71.9%
3872501 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 58.0 3.67e-01 84.9% 19.0%
3332048 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.72 58.0 5.32e-01 86.0% 71.8%
3681397 5059.1.1.17 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TMEM234 0.72 62.0 5.45e-01 91.9% 66.7%
5024245 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.72 58.0 5.32e-01 86.0% 74.5%
3743496 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.71 56.0 4.02e-01 87.2% 30.9%
4612826 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.71 54.0 5.64e-01 80.2% 88.7%
3183024 3755.3.1.46 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › She9_MDM33 0.71 61.0 5.08e-01 90.7% 62.1%
4169938 3684.1.1.44 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DAHL 0.71 53.0 4.80e-01 94.2% 59.1%
3793286 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.71 60.0 4.50e-01 90.7% 81.5%
3935633 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.71 66.0 5.01e-01 100.0% 62.2%
5035050 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 57.0 5.47e-01 95.3% 76.5%
3961547 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.70 53.0 5.01e-01 79.1% 71.0%
3605932 109.4.1.623 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1 0.70 60.0 3.62e-01 95.3% 25.1%
3177117 5041.1.1.20 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › PF26669 0.70 54.0 5.64e-01 82.6% 88.7%
3363819 159.1.1.1 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG 0.70 51.0 4.40e-01 75.6% 52.0%
3676480 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 55.0 5.48e-01 84.9% 80.0%
3642338 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.69 55.0 5.85e-01 82.6% 98.7%
3239087 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.69 57.0 5.22e-01 91.9% 91.3%
3339474 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.69 59.0 5.24e-01 95.3% 65.6%
5029796 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.69 56.0 4.94e-01 86.0% 64.2%
3233475 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.69 61.0 5.03e-01 98.8% 56.0%
3840817 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.69 60.0 4.71e-01 95.3% 61.1%
3794016 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.68 55.0 3.85e-01 86.0% 30.2%
3511449 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.68 55.0 4.63e-01 86.0% 55.0%
3885007 3922.1.1.67 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Val_tRNA-synt_C 0.67 48.0 5.23e-01 82.6% 94.3%
4408647 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.66 56.0 5.26e-01 93.0% 96.2%
4649114 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.66 50.0 4.82e-01 81.4% 77.0%
3504303 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 55.0 5.27e-01 95.3% 79.0%
4660205 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.66 53.0 4.61e-01 88.4% 77.0%
3876590 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.65 56.0 5.67e-01 94.2% 94.1%
4016292 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.65 53.0 4.61e-01 89.5% 91.9%
3250554 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.65 52.0 3.63e-01 87.2% 31.6%
3991853 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.65 49.0 4.56e-01 79.1% 67.6%
3212006 601.24.1.0 alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.64 55.0 4.86e-01 96.5% 70.8%
3965698 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.64 52.0 3.12e-01 89.5% 12.1%
3719904 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.64 50.0 3.34e-01 86.0% 23.2%
3580238 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.64 49.0 4.06e-01 80.2% 69.0%
5073974 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.63 49.0 5.22e-01 84.9% 97.3%
3717701 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.63 53.0 3.61e-01 94.2% 30.3%
3962381 150.5.1.50 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › EspA_EspE 0.63 49.0 5.04e-01 83.7% 92.5%
3368122 3755.3.1.366 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7653 0.63 49.0 3.17e-01 84.9% 19.0%
3490268 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.61 54.0 3.59e-01 95.3% 53.3%
3471229 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.60 50.0 3.45e-01 93.0% 30.5%
3770414 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 49.0 4.64e-01 90.7% 81.9%
3281424 3755.3.1.299 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF445 0.59 44.0 3.44e-01 77.9% 39.4%
3425784 109.4.1.2011 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1, PF26778 0.59 51.0 3.66e-01 94.2% 54.5%
3937968 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 51.0 4.16e-01 100.0% 56.4%
4951651 5042.1.1.1 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › CorA 0.55 38.0 4.17e-01 72.1% 100.0%
D2 medium residues 222-289_353-383
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03387.19 best Herpes_UL46 68.3 7.80e-19 69.7% 15.4%
PF03387.19 Herpes_UL46 31.9 9.00e-08 33.3% 7.4%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.64 39.0 3.38e-01 98.0% 40.0%
3owaA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 56.0 4.75e-01 99.0% 84.2%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.63 54.0 4.38e-01 97.0% 81.2%
4xvxA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 55.0 4.81e-01 100.0% 74.8%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 45.0 4.81e-01 97.0% 89.7%
4y9jA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 54.0 4.74e-01 100.0% 81.9%
2ddhA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 55.0 4.96e-01 100.0% 78.0%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 51.0 3.75e-01 97.0% 75.3%
2uuiA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.58 50.0 4.29e-01 97.0% 59.4%
6elqA01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 49.0 4.12e-01 97.0% 86.9%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.56 48.0 4.31e-01 97.0% 83.2%
4b1bA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 49.0 3.21e-01 98.0% 81.0%
2wyhB04 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.55 43.0 4.32e-01 97.0% 84.2%
3nb0B03 6.10.260.10 Special › Helix non-globular › F1FO ATP Synthase › 0.55 38.0 4.09e-01 70.7% 100.0%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.54 46.0 4.23e-01 93.9% 88.3%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.53 40.0 3.59e-01 78.8% 89.4%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.53 43.0 3.54e-01 87.9% 54.3%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 45.0 4.43e-01 98.0% 84.1%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.53 40.0 3.77e-01 98.0% 66.9%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.53 46.0 3.62e-01 94.9% 75.2%
2pgsA03 1.10.3410.10 Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain 0.51 42.0 4.31e-01 91.9% 100.0%
1x4oA00 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.51 30.0 3.30e-01 96.0% 73.1%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3591490 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.65 56.0 4.92e-01 94.9% 96.0%
4319390 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.62 55.0 4.79e-01 100.0% 72.9%
3829132 604.3.1.35 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF6857 0.61 45.0 3.96e-01 76.8% 61.4%
3437243 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.61 53.0 4.84e-01 97.0% 84.4%
3596209 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.60 53.0 4.55e-01 100.0% 67.3%
4960326 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.60 52.0 4.73e-01 96.0% 70.8%
3961891 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.60 54.0 4.78e-01 100.0% 82.1%
3542442 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.57 51.0 4.49e-01 96.0% 68.6%
3529270 632.1.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid 0.57 46.0 4.70e-01 97.0% 91.6%
3942162 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.57 50.0 3.99e-01 94.9% 90.5%
5065759 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.56 40.0 3.68e-01 77.8% 58.4%
3414710 109.4.1.436 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nipped-B_C 0.56 48.0 3.86e-01 96.0% 52.5%
3515126 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.56 49.0 4.00e-01 93.9% 86.9%
5065191 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.55 46.0 4.43e-01 88.9% 82.7%
3801982 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.54 44.0 4.54e-01 99.0% 96.8%
3932573 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.52 46.0 4.18e-01 100.0% 80.7%
3379095 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.52 47.0 3.88e-01 100.0% 78.9%
3405970 150.1.1.100 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › TMD0_ABC 0.51 44.0 3.60e-01 100.0% 61.0%
5056066 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 44.0 3.53e-01 98.0% 98.1%
3636933 5059.1.1.17 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TMEM234 0.51 45.0 4.00e-01 100.0% 81.3%
4081382 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 44.0 3.38e-01 96.0% 70.2%
3595102 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.50 38.0 4.07e-01 98.0% 97.6%