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tegument_serine-threonine_protein_kinase
Euk-VirMacaca_nemestrina_herpesvirus_7
tegument_serine-threonine_protein_kinase__YP_009253974__Macaca_nemestrina_herpesvirus_7__1846169
Identity
- Accession:
- YP_009253974 ↗
- Protein ID:
- tegument_serine-threonine_protein_kinase
- Kingdom:
- euk
Quality
80.7
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Roseolovirus›
macacine_betaherpesvirus_9
TaxID: 1846169
Cluster
View cluster (78 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 84-234_292-327
Domain cluster:
rep: Phosphotransferase__NP_050248__Human_betaherpesvirus_6B__32604__D157-277_344-373
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06734.19 best | UL97 | 36.2 | 7.90e-09 | 28.3% | 19.2% |
D2
medium
residues 235-291_328-383
Domain cluster:
rep: ganciclovir_kinase__NP_042962__Human_betaherpesvirus_6A__32603__D293-340_364-424
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06734.19 best | UL97 | 82.4 | 5.50e-23 | 74.3% | 33.2% |
D3
medium
residues 384-517
Domain cluster:
rep: E97__YP_007016494__Murid_betaherpesvirus_8__1261657__D382-566
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06734.19 best | UL97 | 89.8 | 3.00e-25 | 55.2% | 39.0% |
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.69 | 33.0 | 4.03e-01 | 76.9% | 70.1% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.66 | 46.0 | 3.92e-01 | 71.6% | 91.3% |
| 1owaA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 33.0 | 3.64e-01 | 79.1% | 59.4% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 38.0 | 4.06e-01 | 94.0% | 69.2% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.60 | 31.0 | 3.76e-01 | 79.1% | 75.3% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.60 | 31.0 | 4.05e-01 | 79.1% | 95.6% |
| 1s3qG00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 43.0 | 4.07e-01 | 77.6% | 82.8% |
| 1s0pA01 | 1.25.40.330 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Adenylate cyclase-associated CAP, N-terminal domain | 0.57 | 43.0 | 3.99e-01 | 79.1% | 100.0% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 35.0 | 3.43e-01 | 99.3% | 55.6% |
| 2i53A02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.56 | 32.0 | 3.44e-01 | 77.6% | 64.0% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.56 | 35.0 | 3.31e-01 | 79.1% | 52.8% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 41.0 | 3.69e-01 | 80.6% | 86.5% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.53 | 33.0 | 3.74e-01 | 79.9% | 82.0% |
| 1zymA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.53 | 37.0 | 3.83e-01 | 70.1% | 84.1% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.52 | 38.0 | 3.66e-01 | 73.9% | 76.5% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 46.0 | 3.95e-01 | 96.3% | 67.3% |
| 2wmoA01 | 1.25.40.410 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DOCK DHR2 domain, lobe A | 0.52 | 40.0 | 4.09e-01 | 100.0% | 81.3% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.52 | 32.0 | 3.51e-01 | 84.3% | 73.5% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.52 | 40.0 | 3.59e-01 | 94.8% | 58.0% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 38.0 | 3.68e-01 | 76.9% | 86.5% |
| 4l8eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 36.0 | 3.98e-01 | 92.5% | 87.3% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 33.0 | 3.16e-01 | 79.1% | 54.0% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.51 | 36.0 | 3.74e-01 | 92.5% | 77.4% |
| 6vmsR00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 45.0 | 3.56e-01 | 96.3% | 78.8% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.51 | 44.0 | 3.36e-01 | 94.0% | 60.1% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 38.0 | 3.40e-01 | 79.1% | 85.9% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5035274 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.66 | 39.0 | 4.13e-01 | 92.5% | 65.0% |
| 5045165 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.65 | 37.0 | 4.23e-01 | 94.0% | 75.0% |
| 4946120 | 102.1.3.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain | 0.64 | 40.0 | 4.13e-01 | 94.0% | 66.4% |
| 3230413 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.62 | 39.0 | 3.31e-01 | 96.3% | 37.0% |
| 4971806 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 43.0 | 3.78e-01 | 73.9% | 95.6% |
| 3980133 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.60 | 41.0 | 3.38e-01 | 70.1% | 51.2% |
| 3254024 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.58 | 43.0 | 3.99e-01 | 76.9% | 81.8% |
| 3991215 | 109.4.1.649 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4807 | 0.58 | 40.0 | 3.75e-01 | 71.6% | 56.1% |
| 5068068 | 601.30.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 | 0.57 | 31.0 | 3.17e-01 | 77.6% | 50.4% |
| 4024116 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 42.0 | 3.71e-01 | 75.4% | 92.3% |
| 3688491 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 40.0 | 3.45e-01 | 72.4% | 96.4% |
| 3388359 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 41.0 | 3.66e-01 | 75.4% | 91.5% |
| 3921752 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.56 | 40.0 | 3.34e-01 | 72.4% | 87.2% |
| 3286104 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.55 | 33.0 | 3.78e-01 | 79.1% | 79.0% |
| 4267909 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.55 | 39.0 | 3.41e-01 | 71.6% | 93.3% |
| 3567471 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.55 | 45.0 | 3.60e-01 | 87.3% | 65.2% |
| 5079159 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 42.0 | 3.72e-01 | 80.6% | 93.5% |
| 4637254 | 5050.1.1.25 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TLC | 0.55 | 43.0 | 3.60e-01 | 85.1% | 88.2% |
| 4264193 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 38.0 | 3.21e-01 | 73.9% | 87.8% |
| 4211332 | 633.10.1.35 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › NKAIN | 0.53 | 38.0 | 4.02e-01 | 73.1% | 92.5% |
| 3939681 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.52 | 48.0 | 3.56e-01 | 100.0% | 56.1% |
| 5053890 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.52 | 42.0 | 4.49e-01 | 90.3% | 98.3% |
| 4412948 | 5050.1.1.25 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TLC | 0.52 | 39.0 | 3.37e-01 | 81.3% | 94.7% |
| 3412554 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.52 | 39.0 | 4.03e-01 | 79.9% | 96.8% |
| 3714082 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.51 | 45.0 | 3.74e-01 | 97.8% | 78.8% |
| 3194196 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.51 | 35.0 | 3.52e-01 | 94.0% | 67.9% |