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tegument_serine_threonine_protein_kinase
Euk-VirPsittacid_alphaherpesvirus_1
tegument_serine_threonine_protein_kinase__NP_944427__Psittacid_alphaherpesvirus_1__50294
Identity
- Accession:
- NP_944427 ↗
- Protein ID:
- tegument_serine_threonine_protein_kinase
- Kingdom:
- euk
Quality
70.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Iltovirus›
Psittacid_alphaherpesvirus_1
TaxID: 50294
Cluster
View cluster (78 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 286-309_346-458
Domain cluster:
rep: tegument_serine_threonine_protein_kinase__NP_066843__Gallid_alphaherpesvirus_3__35250__D318-498
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3qhbA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 47.0 | 4.33e-01 | 82.5% | 92.2% |
| 4by6D02 | 1.25.40.800 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 43.0 | 3.60e-01 | 73.0% | 51.1% |
| 3ayhA00 | 1.20.1250.40 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › RNA Polymerase II, Rpb4 subunit | 0.60 | 31.0 | 3.14e-01 | 70.8% | 48.5% |
| 2yk0A03 | 1.20.58.1930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 41.0 | 3.48e-01 | 73.0% | 66.5% |
| 1aluA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 46.0 | 4.47e-01 | 85.4% | 88.5% |
| 2oi8A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 40.0 | 3.53e-01 | 75.9% | 60.6% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 44.0 | 4.47e-01 | 86.9% | 95.6% |
| 2azjA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 40.0 | 3.18e-01 | 75.9% | 52.9% |
| 6pnjL00 | 1.20.1240.10 | Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI | 0.53 | 40.0 | 3.88e-01 | 79.6% | 80.8% |
| 4kk2B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 40.0 | 3.11e-01 | 82.5% | 72.6% |
| 3ay5A01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.51 | 34.0 | 3.48e-01 | 90.5% | 68.4% |
| 2hkuB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 38.0 | 3.49e-01 | 78.1% | 69.7% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 43.0 | 3.53e-01 | 91.2% | 85.5% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3937581 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 47.0 | 4.03e-01 | 76.6% | 61.0% |
| 3611515 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.62 | 46.0 | 4.04e-01 | 77.4% | 97.5% |
| 3302941 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.60 | 48.0 | 4.13e-01 | 83.2% | 67.8% |
| 3750086 | 150.3.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 | 0.60 | 47.0 | 4.22e-01 | 84.7% | 83.1% |
| 3438721 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.60 | 48.0 | 4.14e-01 | 83.9% | 67.3% |
| 3248617 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.59 | 46.0 | 3.87e-01 | 81.8% | 56.1% |
| 3861565 | 150.3.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 | 0.58 | 46.0 | 4.10e-01 | 85.4% | 82.5% |
| 3450834 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.57 | 35.0 | 4.11e-01 | 74.5% | 87.2% |
| 4946929 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 43.0 | 3.63e-01 | 78.1% | 93.8% |
| 4564645 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.56 | 40.0 | 4.16e-01 | 73.0% | 85.6% |
| 3884473 | 150.3.1.10 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › CNTF | 0.55 | 44.0 | 4.06e-01 | 85.4% | 83.4% |
| 4012252 | 5048.1.1.0 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like | 0.54 | 45.0 | 3.65e-01 | 88.3% | 71.6% |
| 3563412 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.53 | 45.0 | 3.68e-01 | 89.8% | 82.4% |
| 5044770 | 5050.1.1.14 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › ATG22 | 0.53 | 41.0 | 3.49e-01 | 81.0% | 94.5% |
| 3921752 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 43.0 | 3.65e-01 | 89.1% | 84.3% |
| 3740863 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.52 | 38.0 | 3.24e-01 | 74.5% | 79.1% |
| 3875901 | 206.1.1.71 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo | 0.51 | 39.0 | 3.05e-01 | 81.0% | 98.0% |
D2
medium
residues 66-193_241-285
D3
medium
residues 194-240_310-345
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4otpA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.69 | 59.0 | 4.82e-01 | 91.6% | 52.4% |
| 5klkB01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.67 | 44.0 | 2.99e-01 | 97.6% | 19.0% |
| 4qoxA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.67 | 62.0 | 4.79e-01 | 100.0% | 89.0% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 38.0 | 4.24e-01 | 90.4% | 71.2% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 37.0 | 3.49e-01 | 100.0% | 43.4% |
| 2j6lA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.64 | 41.0 | 2.81e-01 | 97.6% | 18.0% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 44.0 | 3.92e-01 | 100.0% | 52.1% |
| 3uebF00 | 3.30.300.100 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like | 0.61 | 44.0 | 4.16e-01 | 75.9% | 100.0% |
| 3akjA02 | 1.10.1070.20 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › | 0.60 | 54.0 | 4.06e-01 | 100.0% | 76.6% |
| 2fhzA00 | 3.30.190.30 | Alpha Beta › 2-Layer Sandwich › Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase › | 0.60 | 50.0 | 4.57e-01 | 89.2% | 84.9% |
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 42.0 | 3.85e-01 | 97.6% | 57.8% |
| 3ermB00 | 1.10.10.710 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like | 0.57 | 33.0 | 3.65e-01 | 88.0% | 71.9% |
| 3ly7A01 | 3.40.50.11830 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 36.0 | 2.89e-01 | 100.0% | 34.2% |
| 3cxjA00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.55 | 46.0 | 3.92e-01 | 94.0% | 75.0% |
| 2hkvA01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.55 | 46.0 | 3.88e-01 | 92.8% | 70.2% |
| 2oarB00 | 1.10.1200.120 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Large-conductance mechanosensitive channel, MscL; domain 1 | 0.55 | 43.0 | 3.75e-01 | 100.0% | 56.0% |
| 1jyaB00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.52 | 42.0 | 3.76e-01 | 90.4% | 73.6% |
| 5cjjB00 | 3.40.50.170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain | 0.52 | 44.0 | 3.44e-01 | 97.6% | 53.2% |
| 1ic8A01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.51 | 46.0 | 4.43e-01 | 100.0% | 96.8% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 41.0 | 3.31e-01 | 83.1% | 90.7% |
| 2wg7A00 | 1.20.90.10 | Mainly Alpha › Up-down Bundle › Phospholipase A2 › Phospholipase A2 domain | 0.51 | 40.0 | 3.52e-01 | 83.1% | 85.1% |
| 3hcyA00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.50 | 46.0 | 3.81e-01 | 100.0% | 99.3% |
| 2qe9B01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.50 | 44.0 | 3.60e-01 | 98.8% | 82.9% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3696503 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.77 | 68.0 | 4.44e-01 | 95.2% | 48.2% |
| 3601192 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.74 | 67.0 | 4.22e-01 | 97.6% | 43.0% |
| 3485296 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.66 | 45.0 | 4.16e-01 | 100.0% | 56.2% |
| 4950905 | 3896.1.2.6 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase › DUF92 | 0.65 | 45.0 | 3.71e-01 | 71.1% | 62.0% |
| 3234976 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.63 | 43.0 | 3.95e-01 | 100.0% | 53.6% |
| 3675304 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.61 | 43.0 | 3.75e-01 | 94.0% | 50.0% |
| 3614763 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.60 | 43.0 | 3.84e-01 | 100.0% | 52.5% |
| 3717870 | 109.4.1.150 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Ufd2P_core | 0.60 | 53.0 | 3.35e-01 | 100.0% | 34.3% |
| 3690513 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.59 | 41.0 | 3.48e-01 | 100.0% | 44.4% |
| 4032929 | 3415.1.1.3 ↗ | alpha complex topology › Concentrative nucleoside transporter › Concentrative nucleoside transporter › Concentrative nucleoside transporter › Nucleos_tra2_N,Nucleos_tra2_C | 0.58 | 52.0 | 3.34e-01 | 100.0% | 42.1% |
| 3884904 | 7515.1.1.2 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Sulfatase | 0.57 | 42.0 | 2.76e-01 | 98.8% | 19.1% |
| 3394225 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.57 | 47.0 | 4.15e-01 | 100.0% | 63.5% |
| 5056801 | 324.1.1.1 ↗ | a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC | 0.56 | 37.0 | 3.31e-01 | 72.3% | 45.6% |
| 4030041 | 4207.1.1.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) | 0.55 | 41.0 | 3.50e-01 | 100.0% | 50.0% |
| 3660160 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.54 | 43.0 | 3.16e-01 | 84.3% | 34.0% |
| 3206826 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.54 | 39.0 | 3.70e-01 | 75.9% | 91.0% |
| 3859550 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.54 | 44.0 | 3.88e-01 | 100.0% | 60.8% |
| 3754268 | 327.19.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › Mlh1_C | 0.54 | 35.0 | 3.30e-01 | 94.0% | 53.0% |
| 3740226 | 5051.1.1.7 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Nramp | 0.54 | 47.0 | 2.98e-01 | 98.8% | 54.1% |
| 3253944 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.54 | 47.0 | 3.72e-01 | 97.6% | 58.3% |
| 3482756 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 48.0 | 3.40e-01 | 100.0% | 83.5% |
| 3784427 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 43.0 | 2.74e-01 | 86.7% | 22.0% |
| 3491910 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.53 | 39.0 | 4.14e-01 | 100.0% | 88.0% |
| 4030384 | 109.4.1.522 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RPAP1_C | 0.53 | 44.0 | 2.71e-01 | 90.4% | 29.2% |
| 4083451 | 192.2.1.20 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ASNSD1-SEP | 0.52 | 44.0 | 4.52e-01 | 100.0% | 93.8% |
| 4681355 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.52 | 43.0 | 3.79e-01 | 100.0% | 60.8% |
| 5048217 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 45.0 | 3.25e-01 | 98.8% | 58.4% |
| 4666900 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.52 | 42.0 | 3.67e-01 | 100.0% | 58.4% |
| 3783273 | 327.19.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › Mlh1_C | 0.51 | 30.0 | 2.95e-01 | 94.0% | 50.0% |
| 3198044 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.51 | 38.0 | 3.69e-01 | 92.8% | 69.5% |
| 3517895 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.50 | 44.0 | 2.89e-01 | 100.0% | 23.2% |
| 3649913 | 5050.1.1.58 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NFD4_C | 0.50 | 44.0 | 3.53e-01 | 98.8% | 85.3% |