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tegument_serine_threonine_protein_kinase
Euk-VirWood_mouse_herpesvirus
tegument_serine_threonine_protein_kinase__YP_010085911__Wood_mouse_herpesvirus__432370
Identity
- Accession:
- YP_010085911 ↗
- Protein ID:
- tegument_serine_threonine_protein_kinase
- Kingdom:
- euk
Quality
82.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Wood_mouse_herpesvirus
TaxID: 432370
Cluster
View cluster (78 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 41-159_218-254
Domain cluster:
rep: ORF36__YP_438159__Ovine_gammaherpesvirus_2__10398__D54-226
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3zh8C01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.60 | 41.0 | 4.68e-01 | 73.7% | 92.2% |
| 4m69A00 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.59 | 46.0 | 3.71e-01 | 82.1% | 62.0% |
| 1vr9A01 | 3.90.1280.20 | Alpha Beta › Alpha-Beta Complex › CBS domain Like › | 0.56 | 20.0 | 2.99e-01 | 87.8% | 73.4% |
| 5gz8A00 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.55 | 48.0 | 3.94e-01 | 92.9% | 65.1% |
| 6bg2A02 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.54 | 41.0 | 4.61e-01 | 87.2% | 99.2% |
| 2vd5B01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.53 | 45.0 | 4.26e-01 | 91.0% | 88.2% |
| 1jyaB00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.52 | 33.0 | 3.69e-01 | 71.2% | 81.8% |
ECOD (61)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3606496 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.73 | 54.0 | 3.90e-01 | 76.9% | 59.1% |
| 3615135 | 206.1.1.74 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr | 0.71 | 53.0 | 3.78e-01 | 76.9% | 46.5% |
| 3609530 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.68 | 54.0 | 4.00e-01 | 82.1% | 68.3% |
| 3185940 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.67 | 49.0 | 3.93e-01 | 74.4% | 62.4% |
| 3361134 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.67 | 52.0 | 4.05e-01 | 80.1% | 64.3% |
| 3325416 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.66 | 56.0 | 4.09e-01 | 87.2% | 62.1% |
| 3825241 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.66 | 54.0 | 4.18e-01 | 83.3% | 56.7% |
| 3407047 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.66 | 51.0 | 3.86e-01 | 79.5% | 50.6% |
| 3223548 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.66 | 50.0 | 3.88e-01 | 78.2% | 60.6% |
| 3585647 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.66 | 50.0 | 3.88e-01 | 78.2% | 54.5% |
| 3275983 | 206.1.2.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt | 0.65 | 47.0 | 3.82e-01 | 74.4% | 92.1% |
| 3412360 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.65 | 51.0 | 3.56e-01 | 80.1% | 50.8% |
| 3608389 | 206.1.1.14 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 | 0.65 | 48.0 | 3.28e-01 | 76.3% | 73.5% |
| None | — | 0.65 | 51.0 | 3.25e-01 | 81.4% | 26.7% | |
| 3907490 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.64 | 50.0 | 4.49e-01 | 79.5% | 92.7% |
| None | — | 0.64 | 51.0 | 3.99e-01 | 82.7% | 65.2% | |
| 3223139 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.63 | 49.0 | 3.84e-01 | 81.4% | 60.9% |
| 4004448 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.63 | 48.0 | 3.69e-01 | 79.5% | 57.9% |
| 3673308 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.62 | 52.0 | 3.85e-01 | 87.2% | 66.1% |
| 3816813 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.62 | 54.0 | 4.10e-01 | 91.7% | 62.1% |
| 4962780 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.61 | 47.0 | 4.12e-01 | 79.5% | 79.8% |
| 3698820 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 43.0 | 3.39e-01 | 73.1% | 99.1% |
| 4025755 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 45.0 | 3.68e-01 | 76.9% | 58.9% |
| 4958069 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.61 | 46.0 | 3.53e-01 | 77.6% | 87.7% |
| 4342305 | 206.1.2.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt | 0.60 | 43.0 | 3.48e-01 | 73.7% | 97.0% |
| 2712923 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.60 | 44.0 | 4.56e-01 | 75.0% | 83.8% |
| 3298634 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 53.0 | 4.01e-01 | 91.7% | 55.3% |
| 3350184 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 54.0 | 3.87e-01 | 92.9% | 55.7% |
| 3305785 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 53.0 | 4.07e-01 | 91.7% | 63.4% |
| 3992291 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 53.0 | 4.09e-01 | 91.7% | 53.8% |
| 3271806 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.59 | 47.0 | 3.33e-01 | 84.0% | 85.8% |
| 3244580 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.59 | 43.0 | 3.24e-01 | 76.3% | 48.4% |
| 3707120 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.59 | 52.0 | 3.88e-01 | 94.9% | 63.1% |
| 3702202 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.59 | 45.0 | 3.53e-01 | 80.1% | 59.4% |
| 3430423 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.59 | 56.0 | 3.44e-01 | 100.0% | 32.0% |
| 3984011 | 206.1.1.33 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › OspG_kinase | 0.59 | 45.0 | 4.29e-01 | 78.2% | 89.7% |
| 3176674 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.59 | 44.0 | 3.26e-01 | 77.6% | 47.5% |
| 3310878 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.58 | 54.0 | 3.54e-01 | 98.1% | 32.5% |
| 3638043 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 44.0 | 3.57e-01 | 77.6% | 52.1% |
| 3421299 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 45.0 | 3.46e-01 | 79.5% | 64.0% |
| 1515972 | 206.1.1.33 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › OspG_kinase | 0.58 | 43.0 | 4.26e-01 | 75.6% | 90.2% |
| 3591562 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 43.0 | 3.52e-01 | 76.9% | 66.7% |
| 3517289 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.58 | 48.0 | 3.72e-01 | 87.2% | 68.8% |
| 4011246 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.57 | 43.0 | 3.29e-01 | 77.6% | 84.7% |
| 3973549 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.57 | 48.0 | 3.84e-01 | 89.1% | 61.7% |
| 3285532 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.56 | 42.0 | 3.44e-01 | 76.9% | 83.6% |
| 3803799 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.56 | 50.0 | 3.96e-01 | 92.9% | 59.3% |
| 3352835 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.56 | 50.0 | 3.76e-01 | 94.2% | 61.4% |
| 3691698 | 206.1.1.82 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF7580 | 0.56 | 49.0 | 3.79e-01 | 95.5% | 78.9% |
| 3500899 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.55 | 50.0 | 3.90e-01 | 95.5% | 69.4% |
| 3366990 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.55 | 49.0 | 3.85e-01 | 93.6% | 60.3% |
| 3752372 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.54 | 48.0 | 3.74e-01 | 93.6% | 59.7% |
| 1823374 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.54 | 42.0 | 3.30e-01 | 80.1% | 61.0% |
| None | — | 0.54 | 48.0 | 3.94e-01 | 92.9% | 66.2% | |
| 4261761 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.54 | 40.0 | 3.20e-01 | 76.9% | 69.5% |
| 3479795 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.53 | 46.0 | 3.59e-01 | 91.7% | 61.9% |
| 3693493 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.52 | 46.0 | 3.74e-01 | 93.6% | 97.9% |
| 3337374 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.52 | 46.0 | 3.27e-01 | 93.6% | 39.1% |
| 3175550 | 206.1.1.10 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Choline_kinase | 0.52 | 46.0 | 3.30e-01 | 92.9% | 86.5% |
| 3673870 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.51 | 45.0 | 3.42e-01 | 92.9% | 55.4% |
| 3454696 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.51 | 45.0 | 3.49e-01 | 94.2% | 65.5% |
D2
medium
residues 160-217_255-303
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7aqbB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.77 | 63.0 | 5.06e-01 | 100.0% | 47.9% |
| 3s95A02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.76 | 66.0 | 5.18e-01 | 100.0% | 48.0% |
| 5lohA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.75 | 61.0 | 5.03e-01 | 99.1% | 51.1% |
| 3uqcD02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.74 | 49.0 | 4.30e-01 | 100.0% | 47.7% |
| 6npyB00 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.74 | 58.0 | 4.90e-01 | 100.0% | 52.7% |
| 4otpA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.73 | 51.0 | 4.57e-01 | 100.0% | 53.8% |
| 4krdA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.72 | 66.0 | 5.16e-01 | 100.0% | 49.3% |
| 3zduA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.71 | 62.0 | 4.89e-01 | 100.0% | 47.8% |
| 4ianA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.71 | 65.0 | 4.91e-01 | 100.0% | 44.3% |
| 8jpdG02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.71 | 63.0 | 4.96e-01 | 100.0% | 49.0% |
| 5cemA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.70 | 60.0 | 4.95e-01 | 100.0% | 54.2% |
| 4ow8A02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.70 | 64.0 | 5.16e-01 | 100.0% | 55.7% |
| 3kmuA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.69 | 63.0 | 5.18e-01 | 100.0% | 58.1% |
| 2wtkC02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.68 | 64.0 | 5.13e-01 | 100.0% | 55.1% |
| 2ydjA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.68 | 59.0 | 4.91e-01 | 94.4% | 56.4% |
| 4itjB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.68 | 63.0 | 5.11e-01 | 100.0% | 55.9% |
| 1vzoA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.68 | 61.0 | 4.77e-01 | 100.0% | 49.0% |
| 4y93A03 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.67 | 62.0 | 5.09e-01 | 100.0% | 58.4% |
| 6vg3B02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.66 | 62.0 | 5.00e-01 | 100.0% | 59.3% |
| 2jiiA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.66 | 61.0 | 4.90e-01 | 100.0% | 56.5% |
| 3vwaA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.59 | 52.0 | 4.70e-01 | 100.0% | 72.0% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.53 | 30.0 | 3.34e-01 | 100.0% | 69.4% |
| 1kblA05 | 1.20.80.30 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.52 | 35.0 | 3.78e-01 | 75.7% | 83.1% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3719381 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.81 | 76.0 | 5.30e-01 | 100.0% | 39.7% |
| 3599371 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.81 | 77.0 | 5.13e-01 | 100.0% | 33.5% |
| 3660160 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.77 | 53.0 | 4.19e-01 | 70.1% | 46.8% |
| 2125846 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.75 | 64.0 | 4.58e-01 | 100.0% | 33.3% |
| 3592426 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.74 | 69.0 | 4.49e-01 | 100.0% | 43.7% |
| 3788691 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.72 | 67.0 | 4.72e-01 | 100.0% | 37.4% |
| 3236347 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.72 | 53.0 | 3.79e-01 | 100.0% | 28.9% |
| 4982702 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.72 | 51.0 | 4.01e-01 | 100.0% | 38.0% |
| 3209716 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.72 | 52.0 | 3.49e-01 | 100.0% | 21.3% |
| 3699594 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.71 | 66.0 | 4.59e-01 | 100.0% | 37.5% |
| 3562325 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.71 | 67.0 | 3.83e-01 | 100.0% | 12.2% |
| 3576324 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.71 | 67.0 | 5.15e-01 | 100.0% | 51.4% |
| 3470391 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.71 | 65.0 | 4.48e-01 | 100.0% | 42.0% |
| 5049007 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.71 | 49.0 | 3.84e-01 | 100.0% | 35.8% |
| 5023556 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.70 | 49.0 | 3.55e-01 | 100.0% | 28.1% |
| 3614950 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.70 | 65.0 | 4.37e-01 | 100.0% | 29.6% |
| 3570115 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.70 | 66.0 | 4.55e-01 | 100.0% | 34.3% |
| 3816949 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.69 | 65.0 | 4.64e-01 | 100.0% | 42.5% |
| None | — | 0.69 | 65.0 | 3.79e-01 | 100.0% | 14.1% | |
| 3314539 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.69 | 65.0 | 4.08e-01 | 100.0% | 22.3% |
| 3495244 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.68 | 65.0 | 4.28e-01 | 100.0% | 28.2% |
| 3264197 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.68 | 64.0 | 4.33e-01 | 100.0% | 30.1% |
| 3815404 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.68 | 64.0 | 4.40e-01 | 100.0% | 32.4% |
| 3356906 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.68 | 64.0 | 4.18e-01 | 100.0% | 26.8% |
| 3674718 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.68 | 63.0 | 4.24e-01 | 100.0% | 40.0% |
| 3686335 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.67 | 63.0 | 4.14e-01 | 100.0% | 26.8% |
| 3466189 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.66 | 62.0 | 4.24e-01 | 100.0% | 33.5% |
| 3782484 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.65 | 56.0 | 3.97e-01 | 91.6% | 33.8% |
| 3240615 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.64 | 58.0 | 4.54e-01 | 98.1% | 59.5% |
| 3222227 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.64 | 59.0 | 4.10e-01 | 100.0% | 40.0% |
| 3689617 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.63 | 59.0 | 4.00e-01 | 100.0% | 38.1% |
| 3904461 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.61 | 57.0 | 4.16e-01 | 100.0% | 40.4% |
| 4030160 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 55.0 | 4.23e-01 | 100.0% | 58.1% |
| 3645097 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.57 | 54.0 | 3.73e-01 | 100.0% | 35.4% |
| 3788706 | 109.4.1.163 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SYMPK_PTA1_N | 0.54 | 41.0 | 2.54e-01 | 80.4% | 30.3% |
| 3839361 | 102.2.1.0 ↗ | alpha arrays › HhH/H2TH › H2TH › H2TH | 0.50 | 34.0 | 3.71e-01 | 94.4% | 87.1% |
D3
medium
residues 304-430
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3whjA00 | 6.10.140.1710 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 31.0 | 3.36e-01 | 73.2% | 55.0% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.58 | 39.0 | 4.44e-01 | 75.6% | 95.6% |
| 2gslF00 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.58 | 34.0 | 3.50e-01 | 92.9% | 57.5% |
| 3n00A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.57 | 43.0 | 3.81e-01 | 78.7% | 77.7% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 42.0 | 3.97e-01 | 77.2% | 87.6% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 37.0 | 3.06e-01 | 70.9% | 37.8% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 31.0 | 3.57e-01 | 81.1% | 73.1% |
| 1xvpB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.55 | 43.0 | 3.49e-01 | 82.7% | 93.1% |
| 1s9qA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.55 | 41.0 | 3.46e-01 | 78.7% | 84.8% |
| 8be0A01 | 3.40.91.90 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain | 0.55 | 42.0 | 3.67e-01 | 81.1% | 99.5% |
| 4okmD00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 48.0 | 3.67e-01 | 98.4% | 50.0% |
| 2qksA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 35.0 | 3.83e-01 | 86.6% | 79.2% |
| 6cnzF00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.54 | 38.0 | 3.61e-01 | 74.0% | 66.5% |
| 1oshA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.54 | 41.0 | 3.53e-01 | 82.7% | 91.2% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.53 | 26.0 | 3.13e-01 | 71.7% | 69.5% |
| 3q2qA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 48.0 | 3.62e-01 | 100.0% | 65.9% |
| 7b00A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.52 | 43.0 | 2.98e-01 | 89.0% | 50.6% |
| 8d7hD01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 46.0 | 4.14e-01 | 96.9% | 72.8% |
| 5eroA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.52 | 39.0 | 3.10e-01 | 82.7% | 61.5% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.51 | 31.0 | 2.74e-01 | 80.3% | 40.8% |
| 2wy4A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 37.0 | 3.62e-01 | 75.6% | 72.7% |
| 3q9oA02 | 3.90.1350.10 | Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain | 0.51 | 40.0 | 3.67e-01 | 83.5% | 71.3% |
| 3pvlA03 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.51 | 35.0 | 3.61e-01 | 71.7% | 74.6% |
| 2mgyA01 | 1.20.1260.100 | Mainly Alpha › Up-down Bundle › Ferritin › TspO/MBR protein | 0.50 | 37.0 | 3.47e-01 | 77.2% | 86.9% |
| 3ipiA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.50 | 44.0 | 3.55e-01 | 100.0% | 99.6% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4079211 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.64 | 47.0 | 4.90e-01 | 74.8% | 100.0% |
| 4665476 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.63 | 45.0 | 3.80e-01 | 74.0% | 55.3% |
| 4958850 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.61 | 27.0 | 3.10e-01 | 77.2% | 55.8% |
| 3740824 | 101.1.10.22 ↗ | alpha arrays › HTH › HTH › Cyclin-like › ORC6 | 0.59 | 42.0 | 4.72e-01 | 74.0% | 100.0% |
| 3912426 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.58 | 42.0 | 3.59e-01 | 75.6% | 72.1% |
| 3740341 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.58 | 27.0 | 2.67e-01 | 76.4% | 39.3% |
| 5051149 | 5065.1.1.3 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 | 0.56 | 45.0 | 3.37e-01 | 85.8% | 66.5% |
| 3600865 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.54 | 36.0 | 3.25e-01 | 73.2% | 49.4% |
| 4027595 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 39.0 | 3.37e-01 | 75.6% | 95.2% |
| 4024127 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.53 | 41.0 | 3.59e-01 | 81.9% | 64.6% |
| 5024430 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.53 | 46.0 | 3.54e-01 | 96.1% | 89.0% |
| 5014330 | 148.1.3.402 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Rad50_zn_hook | 0.53 | 29.0 | 3.14e-01 | 75.6% | 60.9% |
| 4453461 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.52 | 42.0 | 3.51e-01 | 87.4% | 92.4% |
| 5070059 | 3834.1.1.25 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 | 0.51 | 31.0 | 2.55e-01 | 83.5% | 30.0% |
| 3783942 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.51 | 36.0 | 3.49e-01 | 70.9% | 83.6% |
| 4152656 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 36.0 | 2.21e-01 | 73.2% | 79.5% |