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tegument_serine_threonine_protein_kinase
Euk-VirCercopithecine_alphaherpesvirus_2
tegument_serine_threonine_protein_kinase__YP_164455__Cercopithecine_alphaherpesvirus_2__10317
Identity
- Accession:
- YP_164455 ↗
- Protein ID:
- tegument_serine_threonine_protein_kinase
- Kingdom:
- euk
Quality
77.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Cercopithecine_alphaherpesvirus_2
TaxID: 10317
Cluster
View cluster (78 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 331-365_391-509
D2
medium
residues 106-234_305-330
Domain cluster:
rep: Phosphotransferase__NP_050248__Human_betaherpesvirus_6B__32604__D157-277_344-373
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2wtkC01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.72 | 38.0 | 5.06e-01 | 74.8% | 92.1% |
| 3jr1A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.72 | 41.0 | 5.05e-01 | 74.8% | 87.9% |
| 3g2fA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.70 | 40.0 | 5.23e-01 | 74.2% | 100.0% |
| 4c0tA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.70 | 41.0 | 5.29e-01 | 77.4% | 98.9% |
| 4crsA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.60 | 44.0 | 4.69e-01 | 74.2% | 93.3% |
| 5c3vA01 | 3.30.800.10 | Alpha Beta › 2-Layer Sandwich › Phosphatidylinositol Phosphate Kinase II Beta › Phosphatidylinositol Phosphate Kinase II Beta | 0.58 | 43.0 | 4.20e-01 | 74.8% | 93.4% |
| 5f9eA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.58 | 44.0 | 4.69e-01 | 91.0% | 89.6% |
| 5gz8A00 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.55 | 49.0 | 3.98e-01 | 94.2% | 62.9% |
| 4btfA03 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.54 | 38.0 | 4.36e-01 | 97.4% | 100.0% |
| 2f2uB01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.53 | 46.0 | 4.33e-01 | 91.6% | 92.4% |
| 1cjaA01 | 3.30.1010.10 | Alpha Beta › 2-Layer Sandwich › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 | 0.52 | 36.0 | 3.75e-01 | 71.6% | 98.0% |
ECOD (56)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4003305 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.67 | 50.0 | 4.24e-01 | 77.4% | 59.2% |
| 3644839 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.66 | 53.0 | 4.24e-01 | 82.6% | 62.8% |
| 4263654 | 206.1.1.73 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, APH | 0.66 | 54.0 | 4.16e-01 | 85.8% | 62.4% |
| 3723566 | 206.1.1.41 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF3669 | 0.66 | 48.0 | 3.63e-01 | 75.5% | 68.6% |
| 3293466 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.65 | 52.0 | 3.92e-01 | 81.9% | 51.2% |
| None | — | 0.64 | 50.0 | 3.97e-01 | 80.6% | 62.0% | |
| 3840200 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.64 | 44.0 | 3.50e-01 | 70.3% | 55.8% |
| 4022985 | 206.1.1.41 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF3669 | 0.64 | 47.0 | 3.58e-01 | 75.5% | 69.9% |
| 2121624 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.64 | 50.0 | 3.94e-01 | 81.3% | 57.8% |
| 3304155 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.63 | 50.0 | 3.90e-01 | 82.6% | 56.5% |
| 3647739 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.63 | 51.0 | 3.95e-01 | 84.5% | 61.9% |
| 3259209 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.62 | 58.0 | 3.83e-01 | 98.7% | 69.7% |
| 3841474 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.62 | 51.0 | 4.01e-01 | 84.5% | 55.3% |
| 3722388 | 206.1.1.41 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF3669 | 0.62 | 45.0 | 3.76e-01 | 74.2% | 73.1% |
| None | — | 0.62 | 51.0 | 3.99e-01 | 85.8% | 56.8% | |
| 3437535 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.62 | 52.0 | 3.97e-01 | 88.4% | 53.9% |
| 3535709 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.62 | 50.0 | 3.89e-01 | 83.9% | 52.3% |
| 3253861 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.61 | 52.0 | 4.02e-01 | 88.4% | 68.9% |
| 3729327 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 49.0 | 2.94e-01 | 83.2% | 20.2% |
| 4112222 | 206.1.1.18 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › AceK_kinase | 0.59 | 44.0 | 3.50e-01 | 74.8% | 66.1% |
| 3693400 | 206.1.1.74 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr | 0.59 | 56.0 | 3.71e-01 | 100.0% | 46.4% |
| 3668072 | 206.1.1.74 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr | 0.58 | 48.0 | 3.62e-01 | 86.5% | 63.1% |
| 3503175 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.58 | 53.0 | 4.06e-01 | 100.0% | 81.7% |
| 3925996 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.58 | 46.0 | 3.59e-01 | 81.9% | 53.5% |
| 4317590 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 51.0 | 3.89e-01 | 92.3% | 56.3% |
| 3273851 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 53.0 | 3.63e-01 | 100.0% | 43.9% |
| 4977218 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.57 | 47.0 | 3.57e-01 | 85.8% | 68.1% |
| 3454700 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.57 | 51.0 | 4.00e-01 | 93.5% | 53.4% |
| 4435338 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.57 | 49.0 | 3.70e-01 | 91.6% | 56.4% |
| 3638674 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.55 | 51.0 | 4.03e-01 | 100.0% | 81.6% |
| 4337982 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.55 | 51.0 | 3.90e-01 | 100.0% | 47.1% |
| 3601646 | 206.1.2.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase | 0.55 | 50.0 | 3.94e-01 | 100.0% | 81.9% |
| 3647662 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.54 | 51.0 | 3.85e-01 | 100.0% | 54.1% |
| 3248607 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.54 | 49.0 | 3.85e-01 | 100.0% | 83.9% |
| 3356942 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.54 | 49.0 | 3.79e-01 | 100.0% | 84.6% |
| 3529333 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.53 | 48.0 | 3.72e-01 | 96.8% | 56.4% |
| 4950477 | 809.1.1.0 ↗ | a+b two layers › BLIP-like › beta-lactamase-inhibitor protein, BLIP › beta-lactamase-inhibitor protein, BLIP | 0.53 | 25.0 | 3.49e-01 | 74.8% | 92.0% |
| 3274096 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.53 | 48.0 | 3.70e-01 | 100.0% | 85.1% |
| 3276215 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.52 | 48.0 | 3.86e-01 | 100.0% | 90.0% |
| 3275437 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.52 | 48.0 | 3.83e-01 | 100.0% | 83.8% |
| 3496279 | 206.1.2.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › Ins_P5_2-kin | 0.52 | 45.0 | 3.21e-01 | 93.5% | 93.8% |
| 3204278 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.52 | 48.0 | 3.36e-01 | 100.0% | 52.2% |
| 3407102 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.52 | 48.0 | 3.76e-01 | 100.0% | 77.8% |
| 3493701 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.52 | 47.0 | 3.72e-01 | 100.0% | 84.3% |
| 3900870 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.52 | 47.0 | 3.63e-01 | 100.0% | 84.0% |
| 4951171 | 809.1.1.0 ↗ | a+b two layers › BLIP-like › beta-lactamase-inhibitor protein, BLIP › beta-lactamase-inhibitor protein, BLIP | 0.52 | 25.0 | 3.56e-01 | 72.9% | 100.0% |
| 3938890 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.51 | 47.0 | 3.79e-01 | 100.0% | 84.3% |
| 3727614 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.51 | 47.0 | 3.86e-01 | 99.4% | 57.3% |
| 3495958 | 206.1.2.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase | 0.51 | 47.0 | 3.90e-01 | 100.0% | 94.1% |
| 3499420 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.51 | 47.0 | 3.75e-01 | 100.0% | 82.7% |
| 3198158 | 206.1.1.83 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1, PK_Tyr_Ser-Thr | 0.51 | 44.0 | 3.39e-01 | 94.8% | 60.3% |
| 3469420 | 206.1.2.2 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › PIP5K | 0.51 | 47.0 | 3.62e-01 | 100.0% | 75.0% |
| 5065362 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.51 | 47.0 | 3.60e-01 | 100.0% | 55.4% |
| 3193289 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.51 | 45.0 | 3.30e-01 | 96.1% | 46.0% |
| 6632 | 241.1.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › Invas_SpaK | 0.51 | 34.0 | 3.65e-01 | 74.2% | 78.4% |
| 3558331 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.51 | 45.0 | 3.19e-01 | 96.8% | 37.0% |
D3
medium
residues 235-304_366-390