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term1_saliva_scaffold_5_curated_closed_gap_prodigal-single.1__X__X__00133
Bact-Virterm1_saliva_scaffold_5_curated_closed_gap_prodigal-single.1__X__X__00133
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 162-210
Domain cluster:
representative
CATH (53)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1s28A00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.77 | 66.0 | 4.90e-01 | 100.0% | 68.5% |
| 2jkgA00 | 3.30.450.30 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic | 0.76 | 63.0 | 4.41e-01 | 100.0% | 28.5% |
| 1b9mA03 | 2.40.50.100 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain | 0.66 | 48.0 | 4.30e-01 | 91.8% | 54.9% |
| 5yjwA00 | 3.50.50.100 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › | 0.65 | 55.0 | 3.20e-01 | 95.9% | 73.3% |
| 2y3aA01 | 3.10.20.770 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.65 | 44.0 | 2.75e-01 | 71.4% | 51.4% |
| 5mmiG01 | 3.90.930.12 | Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 | 0.65 | 54.0 | 4.59e-01 | 95.9% | 97.6% |
| 2v79A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 43.0 | 3.28e-01 | 79.6% | 31.3% |
| 1gutA00 | 2.40.50.100 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain | 0.62 | 47.0 | 4.31e-01 | 91.8% | 61.2% |
| 3mfiA04 | 3.30.1490.100 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain | 0.61 | 52.0 | 4.03e-01 | 100.0% | 54.6% |
| 3lp5A00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.61 | 53.0 | 3.39e-01 | 100.0% | 35.2% |
| 4lniJ01 | 3.10.20.70 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Glutamine synthetase, N-terminal domain | 0.60 | 48.0 | 3.94e-01 | 95.9% | 91.3% |
| 6aqgA01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.59 | 47.0 | 3.56e-01 | 95.9% | 51.1% |
| 4hppA01 | 3.10.20.70 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Glutamine synthetase, N-terminal domain | 0.59 | 43.0 | 3.59e-01 | 83.7% | 90.1% |
| 1xttB00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.59 | 43.0 | 2.81e-01 | 77.6% | 18.3% |
| 4u7cB04 | 3.30.1490.100 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain | 0.59 | 49.0 | 3.93e-01 | 100.0% | 59.6% |
| 6julA02 | 3.30.1490.100 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain | 0.59 | 49.0 | 4.07e-01 | 100.0% | 67.7% |
| 6hoxA01 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.58 | 49.0 | 3.22e-01 | 100.0% | 22.4% |
| 5jk0B01 | 1.10.443.10 | Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core | 0.58 | 45.0 | 3.15e-01 | 87.8% | 33.5% |
| 2h7fX02 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.57 | 49.0 | 3.16e-01 | 98.0% | 28.2% |
| 1a41A01 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.57 | 45.0 | 3.45e-01 | 89.8% | 40.9% |
| 1se8A02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.57 | 46.0 | 3.67e-01 | 95.9% | 75.7% |
| 1jb7A02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.57 | 48.0 | 3.74e-01 | 100.0% | 66.4% |
| 3pvlA02 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.57 | 47.0 | 3.92e-01 | 100.0% | 76.0% |
| 4a55A01 | 3.10.20.770 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.57 | 45.0 | 2.78e-01 | 89.8% | 34.5% |
| 5odnC00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.57 | 43.0 | 3.60e-01 | 91.8% | 50.0% |
| 3f02B02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.57 | 45.0 | 3.62e-01 | 89.8% | 66.0% |
| 4hscX04 | 2.60.40.1430 | Mainly Beta › Sandwich › Immunoglobulin-like › Perfringolysin, domain 4 | 0.57 | 47.0 | 3.77e-01 | 100.0% | 78.2% |
| 1utbB01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 44.0 | 3.39e-01 | 87.8% | 93.8% |
| 1mtpA02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.56 | 45.0 | 3.73e-01 | 89.8% | 60.4% |
| 3t91B00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.55 | 46.0 | 3.07e-01 | 95.9% | 38.4% |
| 3h20A01 | 3.30.1490.240 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain | 0.55 | 39.0 | 3.72e-01 | 93.9% | 60.6% |
| 2v1yA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.55 | 39.0 | 3.32e-01 | 83.7% | 41.6% |
| 1tg0A00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.55 | 37.0 | 3.39e-01 | 81.6% | 51.5% |
| 3goeA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.55 | 37.0 | 3.21e-01 | 79.6% | 43.8% |
| 6njyA01 | 3.30.70.1900 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 39.0 | 3.16e-01 | 85.7% | 96.7% |
| 7trwA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 45.0 | 3.68e-01 | 100.0% | 98.0% |
| 2wweA01 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.54 | 48.0 | 3.75e-01 | 100.0% | 81.7% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.54 | 47.0 | 2.87e-01 | 100.0% | 64.5% |
| 1wyuA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.53 | 40.0 | 2.50e-01 | 79.6% | 100.0% |
| 4mfzA02 | 3.40.630.120 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › | 0.53 | 40.0 | 2.96e-01 | 85.7% | 31.3% |
| 1zr6A02 | 3.30.465.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › | 0.53 | 36.0 | 2.66e-01 | 85.7% | 24.8% |
| 4oxiA01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.53 | 44.0 | 2.63e-01 | 98.0% | 87.6% |
| 1wx9A00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 42.0 | 3.57e-01 | 91.8% | 86.0% |
| 2i02A00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.53 | 44.0 | 3.24e-01 | 95.9% | 35.0% |
| 4yfbC02 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.53 | 37.0 | 3.25e-01 | 75.5% | 82.1% |
| 2z3gB00 | 3.40.140.10 | Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 | 0.52 | 42.0 | 3.28e-01 | 98.0% | 70.9% |
| 1v2yA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.52 | 41.0 | 3.32e-01 | 93.9% | 85.7% |
| 2jz6A01 | 2.30.170.40 | Mainly Beta › Roll › Ribosomal Protein L24e; Chain: T; › Ribosomal protein L28/L24 | 0.51 | 36.0 | 3.64e-01 | 91.8% | 78.0% |
| 1z2mA02 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.51 | 40.0 | 3.51e-01 | 89.8% | 92.2% |
| 2wyqA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.50 | 39.0 | 3.48e-01 | 89.8% | 100.0% |
| 1ttnA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.50 | 40.0 | 3.64e-01 | 95.9% | 100.0% |
| 5mj6A03 | 2.60.40.1910 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.50 | 40.0 | 3.53e-01 | 95.9% | 90.0% |
| 1gcbA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.50 | 44.0 | 2.54e-01 | 100.0% | 11.7% |
ECOD (68)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4024768 | 330.3.1.7 ↗ | a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like › AP2 | 0.94 | 88.0 | 8.41e-01 | 100.0% | 90.9% |
| 4026211 | 252.2.1.1 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 | 0.93 | 85.0 | 8.49e-01 | 98.0% | 98.0% |
| 4030681 | 252.2.1.1 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 | 0.91 | 79.0 | 7.11e-01 | 93.9% | 72.3% |
| 4026802 | 252.2.1.0 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like | 0.91 | 81.0 | 5.87e-01 | 95.9% | 41.7% |
| 4025434 | 252.2.1.1 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 | 0.90 | 78.0 | 6.67e-01 | 93.9% | 62.7% |
| 4026200 | 252.2.1.0 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like | 0.89 | 81.0 | 7.09e-01 | 100.0% | 75.7% |
| 4029445 | 252.2.1.1 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 | 0.88 | 76.0 | 7.33e-01 | 93.9% | 85.5% |
| 4026577 | 252.2.1.1 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 | 0.87 | 79.0 | 7.63e-01 | 100.0% | 90.9% |
| 4029439 | 252.2.1.0 ↗ | a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like | 0.85 | 76.0 | 6.76e-01 | 100.0% | 73.9% |
| 169012 | 223.2.1.1 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Profilin | 0.77 | 68.0 | 4.64e-01 | 100.0% | 30.6% |
| 4595166 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.75 | 51.0 | 3.27e-01 | 71.4% | 30.7% |
| 3255946 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.71 | 50.0 | 4.20e-01 | 73.5% | 45.0% |
| 3877843 | 3075.1.1.2 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › UPF0561 | 0.70 | 50.0 | 4.55e-01 | 75.5% | 60.9% |
| 3225917 | 2498.1.1.23 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M49 | 0.70 | 48.0 | 2.63e-01 | 71.4% | 6.5% |
| 3587631 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.69 | 55.0 | 3.94e-01 | 100.0% | 30.7% |
| 5038957 | 323.1.1.1 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › 2-oxoacid_dh | 0.69 | 52.0 | 3.33e-01 | 87.8% | 86.2% |
| 4947471 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.68 | 48.0 | 3.03e-01 | 73.5% | 28.5% |
| 4948264 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.68 | 52.0 | 4.38e-01 | 81.6% | 56.2% |
| 4058734 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.68 | 54.0 | 4.61e-01 | 100.0% | 52.6% |
| 4023956 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.67 | 57.0 | 4.22e-01 | 95.9% | 82.3% |
| 4405858 | 2003.1.1.3 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short | 0.66 | 47.0 | 2.88e-01 | 77.6% | 11.7% |
| 3250437 | 239.4.1.0 ↗ | beta barrels › Ribosomal protein L25-like › Glutamine synthetase, N-terminal domain › Glutamine synthetase, N-terminal domain | 0.65 | 54.0 | 4.06e-01 | 93.9% | 88.8% |
| 4962375 | 2484.1.1.49 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N | 0.65 | 54.0 | 4.03e-01 | 98.0% | 35.6% |
| 3203514 | 2484.1.1.24 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.65 | 57.0 | 4.03e-01 | 100.0% | 32.3% |
| 3164555 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.65 | 55.0 | 3.97e-01 | 98.0% | 31.3% |
| 4995243 | 3501.1.1.1 ↗ | a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 | 0.65 | 50.0 | 4.46e-01 | 87.8% | 90.7% |
| 4945973 | 2484.1.1.49 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N | 0.65 | 54.0 | 4.05e-01 | 100.0% | 38.5% |
| 3174631 | 2003.1.1.3 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short | 0.65 | 46.0 | 2.80e-01 | 77.6% | 11.3% |
| 138326 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.64 | 48.0 | 3.53e-01 | 81.6% | 34.5% |
| 5039446 | 2484.1.1.49 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N | 0.64 | 54.0 | 3.97e-01 | 100.0% | 37.1% |
| 3237267 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.62 | 49.0 | 4.01e-01 | 95.9% | 44.8% |
| 5068175 | 2484.1.1.49 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N | 0.62 | 51.0 | 3.90e-01 | 100.0% | 43.1% |
| 4995715 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.62 | 49.0 | 3.24e-01 | 100.0% | 30.6% |
| 3423775 | 601.16.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218 | 0.61 | 54.0 | 3.81e-01 | 100.0% | 87.7% |
| 3607731 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.61 | 44.0 | 3.58e-01 | 87.8% | 38.4% |
| 3963148 | 2.1.1.15 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon | 0.60 | 47.0 | 3.88e-01 | 91.8% | 48.0% |
| 3497573 | 221.1.1.36 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › FERM_N | 0.60 | 42.0 | 3.11e-01 | 87.8% | 27.4% |
| 4928680 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.60 | 47.0 | 3.14e-01 | 85.7% | 48.4% |
| 3484153 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.59 | 48.0 | 2.70e-01 | 91.8% | 95.9% |
| 3430282 | 601.1.2.68 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DUF1218 | 0.58 | 52.0 | 3.54e-01 | 100.0% | 98.2% |
| 3578208 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.58 | 38.0 | 3.73e-01 | 87.8% | 60.0% |
| 3591474 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.57 | 50.0 | 3.29e-01 | 100.0% | 67.3% |
| 3227661 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.56 | 45.0 | 2.85e-01 | 98.0% | 44.0% |
| 1211453 | 2498.1.1.23 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M49 | 0.56 | 49.0 | 2.72e-01 | 100.0% | 17.3% |
| 4355046 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.56 | 43.0 | 3.77e-01 | 100.0% | 52.6% |
| 5078418 | 7584.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins | 0.55 | 41.0 | 2.60e-01 | 81.6% | 65.5% |
| 4353121 | 218.1.1.8 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA | 0.55 | 43.0 | 3.65e-01 | 100.0% | 56.0% |
| 3508428 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 46.0 | 3.09e-01 | 91.8% | 30.6% |
| 3194492 | 109.4.1.1297 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TIMELESS, PF27570 | 0.54 | 46.0 | 2.51e-01 | 91.8% | 24.4% |
| 3219578 | 221.1.1.2 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin | 0.53 | 37.0 | 3.10e-01 | 87.8% | 38.9% |
| 3614862 | 4015.1.1.1 ↗ | alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 | 0.53 | 47.0 | 3.05e-01 | 100.0% | 50.9% |
| 3715658 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.53 | 41.0 | 2.63e-01 | 87.8% | 68.8% |
| 3544242 | 221.1.1.69 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › SNX17-27-31_F1_FERM | 0.53 | 42.0 | 3.43e-01 | 95.9% | 73.3% |
| 3284000 | 4107.1.1.2 ↗ | alpha arrays › Jann2411-like › Jann2411-like › Jann2411-like › zf-CGNR | 0.53 | 43.0 | 3.01e-01 | 95.9% | 49.4% |
| 3560843 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.53 | 41.0 | 3.29e-01 | 91.8% | 90.9% |
| 4017638 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.53 | 41.0 | 3.22e-01 | 87.8% | 90.0% |
| 3839768 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.53 | 42.0 | 2.65e-01 | 100.0% | 20.9% |
| 3910235 | 221.1.1.36 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › FERM_N | 0.52 | 42.0 | 3.42e-01 | 91.8% | 94.7% |
| 3400530 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.51 | 41.0 | 3.11e-01 | 91.8% | 90.0% |
| 3593127 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.51 | 40.0 | 3.39e-01 | 89.8% | 85.6% |
| 3621904 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.51 | 39.0 | 3.14e-01 | 91.8% | 88.7% |
| 3171102 | 221.1.1.113 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA_3 | 0.51 | 40.0 | 3.03e-01 | 89.8% | 79.2% |
| 5018572 | 304.48.1.72 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_N | 0.51 | 45.0 | 3.03e-01 | 100.0% | 45.6% |
| 3855388 | 221.1.1.76 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA_2 | 0.51 | 39.0 | 3.29e-01 | 89.8% | 87.4% |
| 3938317 | 389.1.1.0 ↗ | few secondary structure elements › EGF-like › EGF-related › EGF/Laminin | 0.51 | 33.0 | 3.59e-01 | 75.5% | 80.0% |
| 3501223 | 7516.1.1.8 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Galactosyl_T | 0.51 | 40.0 | 2.58e-01 | 95.9% | 75.2% |
| 3592085 | 4015.1.1.1 ↗ | alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 | 0.50 | 43.0 | 2.70e-01 | 95.9% | 25.8% |
| 3897327 | 2.1.1.241 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Rsm22 | 0.50 | 39.0 | 3.82e-01 | 89.8% | 87.3% |
D2
medium
residues 1-51
Domain cluster:
representative
CATH (62)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4hs5A00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.71 | 55.0 | 4.42e-01 | 86.3% | 44.8% |
| 4jpdA00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.71 | 55.0 | 4.34e-01 | 86.3% | 43.1% |
| 4ifsA01 | 2.30.29.150 | Mainly Beta › Roll › PH-domain like › | 0.68 | 53.0 | 3.95e-01 | 86.3% | 62.1% |
| 2nn5A00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.67 | 52.0 | 3.70e-01 | 88.2% | 76.6% |
| 1r7lA00 | 3.30.2120.10 | Alpha Beta › 2-Layer Sandwich › Bacillus phage protein › Bacillus phage protein-like | 0.67 | 51.0 | 4.09e-01 | 84.3% | 43.7% |
| 4a17E01 | 3.90.930.12 | Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 | 0.66 | 51.0 | 4.38e-01 | 88.2% | 83.5% |
| 2gcjA01 | 2.30.29.150 | Mainly Beta › Roll › PH-domain like › | 0.65 | 50.0 | 3.75e-01 | 86.3% | 59.0% |
| 4ci8A01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.63 | 54.0 | 3.30e-01 | 98.0% | 78.9% |
| 7whgG02 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.63 | 47.0 | 3.86e-01 | 80.4% | 100.0% |
| 1vx7H01 | 3.90.930.12 | Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 | 0.63 | 48.0 | 4.18e-01 | 88.2% | 84.7% |
| 6grrB01 | 3.30.457.10 | Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › Copper amine oxidase-like, N-terminal domain | 0.63 | 51.0 | 4.43e-01 | 90.2% | 81.0% |
| 2fn0B00 | 3.60.120.10 | Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase | 0.62 | 45.0 | 2.74e-01 | 84.3% | 10.7% |
| 2f2hA01 | 2.60.40.1760 | Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) | 0.61 | 50.0 | 3.34e-01 | 100.0% | 43.3% |
| 2ltrA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.60 | 52.0 | 4.15e-01 | 100.0% | 70.5% |
| 4chmB00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.60 | 53.0 | 3.95e-01 | 98.0% | 52.4% |
| 1g29102 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.60 | 43.0 | 4.55e-01 | 92.2% | 91.1% |
| 1wiiA01 | 2.20.25.190 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.60 | 50.0 | 4.71e-01 | 94.1% | 77.4% |
| 3hrsA02 | 2.30.30.90 | Mainly Beta › Roll › SH3 type barrels. › Ferrous iron transport protein A (FeoA) | 0.59 | 42.0 | 3.73e-01 | 74.5% | 81.6% |
| 4iapA01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.59 | 44.0 | 3.63e-01 | 80.4% | 45.7% |
| 2yyzA02 | 2.40.50.100 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain | 0.59 | 43.0 | 4.19e-01 | 100.0% | 70.7% |
| 4chjA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.59 | 53.0 | 3.94e-01 | 100.0% | 54.8% |
| 4ms4B02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.59 | 44.0 | 3.07e-01 | 84.3% | 27.2% |
| 3fssA02 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.58 | 43.0 | 3.73e-01 | 82.4% | 64.0% |
| 3nvnA00 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.58 | 49.0 | 2.98e-01 | 100.0% | 39.4% |
| 6o5cA02 | 2.30.30.90 | Mainly Beta › Roll › SH3 type barrels. › Ferrous iron transport protein A (FeoA) | 0.58 | 42.0 | 3.72e-01 | 76.5% | 81.6% |
| 2f09A00 | 2.40.128.200 | Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor | 0.58 | 43.0 | 3.83e-01 | 84.3% | 79.3% |
| 2cs7A00 | 3.10.50.90 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.58 | 40.0 | 3.96e-01 | 72.5% | 67.3% |
| 2bzyA00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.57 | 34.0 | 3.27e-01 | 74.5% | 46.8% |
| 1yqeA01 | 3.40.630.50 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › AF0625-like | 0.57 | 42.0 | 3.02e-01 | 86.3% | 94.1% |
| 1wi1A01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.56 | 42.0 | 3.43e-01 | 86.3% | 44.1% |
| 3igfA02 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.56 | 43.0 | 3.80e-01 | 88.2% | 56.8% |
| 2dmyA00 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.56 | 46.0 | 3.85e-01 | 98.0% | 60.8% |
| 6qp7A01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.56 | 45.0 | 2.68e-01 | 96.1% | 94.2% |
| 2q2tA03 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.56 | 44.0 | 3.66e-01 | 96.1% | 89.6% |
| 1go3E01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.55 | 46.0 | 3.89e-01 | 98.0% | 79.8% |
| 4e69A00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.55 | 45.0 | 2.86e-01 | 100.0% | 51.6% |
| 7nn3B01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.55 | 47.0 | 2.91e-01 | 100.0% | 49.4% |
| 3k1lA01 | 3.30.457.40 | Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › | 0.55 | 41.0 | 3.53e-01 | 88.2% | 80.4% |
| 3p54A02 | 3.30.67.10 | Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 | 0.55 | 44.0 | 4.05e-01 | 94.1% | 78.9% |
| 6epkA02 | 3.30.67.10 | Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 | 0.54 | 44.0 | 4.03e-01 | 94.1% | 81.7% |
| 6v55A02 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 46.0 | 3.16e-01 | 100.0% | 56.4% |
| 3ak5D02 | 2.160.20.20 | Mainly Beta › 3 Solenoid › Pectate Lyase C-like › | 0.54 | 47.0 | 2.62e-01 | 100.0% | 12.3% |
| 6o15A02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.54 | 43.0 | 2.93e-01 | 96.1% | 80.3% |
| 3d3rA00 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.54 | 41.0 | 3.60e-01 | 96.1% | 54.2% |
| 2zxrA01 | 2.40.50.460 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.53 | 44.0 | 3.21e-01 | 98.0% | 38.6% |
| 3kdgB01 | 3.30.1540.20 | Alpha Beta › 2-Layer Sandwich › formyl-coa transferase, domain 3 › MutL, C-terminal domain, dimerisation subdomain | 0.53 | 43.0 | 3.66e-01 | 96.1% | 74.2% |
| 1cjaA01 | 3.30.1010.10 | Alpha Beta › 2-Layer Sandwich › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4 | 0.53 | 46.0 | 3.32e-01 | 98.0% | 58.7% |
| 6kwzA00 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.53 | 43.0 | 3.53e-01 | 92.2% | 93.9% |
| 4hdoA03 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.53 | 45.0 | 3.80e-01 | 100.0% | 56.5% |
| 5cmlA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.53 | 41.0 | 2.71e-01 | 88.2% | 25.4% |
| 8aasC01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.53 | 44.0 | 3.59e-01 | 98.0% | 55.9% |
| 1l1oF01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.53 | 42.0 | 3.31e-01 | 98.0% | 64.1% |
| 5zx8A00 | 3.40.50.1470 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase | 0.51 | 41.0 | 2.98e-01 | 100.0% | 96.2% |
| 2z1cB00 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.51 | 38.0 | 3.56e-01 | 98.0% | 62.2% |
| 3h09B02 | 2.160.20.20 | Mainly Beta › 3 Solenoid › Pectate Lyase C-like › | 0.51 | 44.0 | 2.57e-01 | 100.0% | 17.6% |
| 6w0pA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.51 | 36.0 | 2.17e-01 | 76.5% | 22.5% |
| 3k0xA00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.51 | 43.0 | 3.57e-01 | 100.0% | 55.6% |
| 3n40P02 | 2.60.40.3200 | Mainly Beta › Sandwich › Immunoglobulin-like › Alphavirus E2 glycoprotein, A domain | 0.51 | 42.0 | 2.82e-01 | 98.0% | 49.8% |
| 2nttA02 | 2.40.50.110 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.51 | 41.0 | 3.81e-01 | 98.0% | 85.7% |
| 1dq3A02 | 3.30.160.90 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.50 | 42.0 | 3.81e-01 | 100.0% | 80.3% |
| 2jmcA00 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.50 | 42.0 | 3.74e-01 | 98.0% | 80.5% |
| 1x43A01 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.50 | 35.0 | 3.37e-01 | 76.5% | 90.3% |
ECOD (76)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4660347 | 12.3.1.6 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Bgal_small_N | 0.69 | 60.0 | 3.71e-01 | 100.0% | 43.9% |
| 4995140 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.68 | 53.0 | 3.84e-01 | 86.3% | 58.6% |
| 3224950 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.66 | 50.0 | 4.06e-01 | 84.3% | 43.8% |
| 3621099 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.66 | 50.0 | 3.97e-01 | 82.4% | 54.3% |
| 5042618 | 896.1.1.0 ↗ | a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related | 0.66 | 47.0 | 4.32e-01 | 74.5% | 60.0% |
| 4928066 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.65 | 49.0 | 3.48e-01 | 86.3% | 46.6% |
| 5014319 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.65 | 54.0 | 5.06e-01 | 100.0% | 89.7% |
| 3988063 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.63 | 51.0 | 4.85e-01 | 96.1% | 87.7% |
| 4589583 | 2008.1.1.191 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_HpaII | 0.63 | 48.0 | 3.35e-01 | 84.3% | 37.0% |
| 5052723 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.63 | 47.0 | 4.10e-01 | 92.2% | 52.5% |
| 3976843 | 9.11.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like › MliC | 0.63 | 47.0 | 4.03e-01 | 84.3% | 67.4% |
| 4180663 | 2.4.1.1 ↗ | beta barrels › OB-fold › MOP-like › MOP-like › TOBE | 0.62 | 50.0 | 3.79e-01 | 92.2% | 36.8% |
| 3945055 | 2484.2.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Methylated DNA-protein cysteine methyltransferase domain › Methylated DNA-protein cysteine methyltransferase domain › Methyltransf_1N | 0.62 | 48.0 | 4.18e-01 | 90.2% | 97.6% |
| 3992786 | 11.1.1.1176 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Beta-prop_Rol-3 | 0.62 | 47.0 | 2.91e-01 | 84.3% | 44.3% |
| 5045441 | 192.2.1.88 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › NFACT_N | 0.61 | 41.0 | 2.85e-01 | 94.1% | 20.6% |
| 4580534 | 241.3.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › N domain of copper amine oxidase › N domain of copper amine oxidase › Cu_amine_oxidN1 | 0.61 | 55.0 | 4.26e-01 | 100.0% | 66.4% |
| 4989302 | 512.1.1.2 ↗ | a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_2nd | 0.61 | 47.0 | 3.22e-01 | 88.2% | 34.6% |
| 3957580 | 2003.1.2.24 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 | 0.61 | 40.0 | 2.83e-01 | 72.5% | 21.3% |
| 3218510 | 145.1.1.0 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain | 0.61 | 44.0 | 3.71e-01 | 86.3% | 42.9% |
| 4934385 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.60 | 46.0 | 3.16e-01 | 84.3% | 41.6% |
| 4026536 | 220.1.1.53 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › ISP1_C | 0.60 | 53.0 | 3.95e-01 | 98.0% | 52.4% |
| 5066347 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.60 | 46.0 | 3.32e-01 | 84.3% | 52.7% |
| 3516108 | 2004.1.1.250 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd | 0.60 | 50.0 | 3.01e-01 | 98.0% | 81.5% |
| 4023915 | 220.1.1.53 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › ISP1_C | 0.60 | 54.0 | 4.10e-01 | 100.0% | 67.8% |
| 4585317 | 4.1.1.175 ↗ | beta barrels › SH3 › SH3 › SH3 › MSSS | 0.60 | 37.0 | 3.71e-01 | 74.5% | 58.2% |
| 4931058 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.60 | 39.0 | 2.79e-01 | 94.1% | 20.6% |
| 3903835 | 224.1.1.2 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin | 0.59 | 45.0 | 3.62e-01 | 84.3% | 81.0% |
| 4945655 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.59 | 52.0 | 4.20e-01 | 100.0% | 51.0% |
| 3615326 | 7039.1.1.0 ↗ | a+b complex topology › Helical domain of PCIF1/CAPAM › Helical domain of PCIF1/CAPAM › Helical domain of PCIF1/CAPAM | 0.59 | 49.0 | 3.14e-01 | 94.1% | 34.2% |
| 1283866 | 220.1.1.51 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › ISP3_C | 0.59 | 53.0 | 3.94e-01 | 100.0% | 54.8% |
| 4935088 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.59 | 39.0 | 2.95e-01 | 94.1% | 26.9% |
| 3176830 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.58 | 44.0 | 3.56e-01 | 86.3% | 40.0% |
| 4545531 | 220.1.1.255 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_10 | 0.58 | 51.0 | 4.39e-01 | 100.0% | 98.8% |
| 4030191 | 5.1.5.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 | 0.58 | 48.0 | 2.70e-01 | 100.0% | 14.9% |
| 4034423 | 4.8.1.26 ↗ | beta barrels › SH3 › Chromo domain-like › Chromo domain-like › bPH_8 | 0.58 | 49.0 | 4.18e-01 | 98.0% | 81.2% |
| 5030534 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.58 | 43.0 | 3.80e-01 | 88.2% | 54.7% |
| 3604511 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.58 | 48.0 | 4.75e-01 | 96.1% | 89.1% |
| 4960634 | 3755.3.1.127 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NFACT_N | 0.57 | 37.0 | 2.66e-01 | 92.2% | 20.0% |
| 4451554 | 4337.1.1.0 ↗ | a+b two layers › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain | 0.57 | 46.0 | 3.86e-01 | 94.1% | 81.9% |
| 4029057 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.57 | 50.0 | 3.99e-01 | 100.0% | 64.8% |
| 4028811 | 10.13.1.0 ↗ | beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A | 0.57 | 51.0 | 3.90e-01 | 100.0% | 65.2% |
| 3717071 | 7579.1.1.0 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases | 0.57 | 49.0 | 2.96e-01 | 98.0% | 86.8% |
| 3936608 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.57 | 42.0 | 3.31e-01 | 82.4% | 36.4% |
| 3918968 | 5.1.4.12 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Sema | 0.57 | 48.0 | 2.98e-01 | 100.0% | 49.8% |
| 4956663 | 3291.1.1.49 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › NFACT_N | 0.57 | 38.0 | 2.96e-01 | 94.1% | 28.8% |
| 3292855 | 220.1.1.36 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_12 | 0.57 | 49.0 | 3.73e-01 | 98.0% | 59.2% |
| 3693093 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.57 | 49.0 | 3.69e-01 | 98.0% | 57.6% |
| 5049640 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.56 | 50.0 | 4.28e-01 | 98.0% | 64.6% |
| 4406214 | 101.1.2.70 ↗ | alpha arrays › HTH › HTH › winged helix domain › PqqD | 0.56 | 44.0 | 3.67e-01 | 88.2% | 76.3% |
| 3723092 | 220.1.1.36 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_12 | 0.56 | 48.0 | 3.65e-01 | 96.1% | 59.2% |
| 5024500 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.56 | 36.0 | 2.91e-01 | 92.2% | 31.4% |
| 3775796 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.56 | 47.0 | 3.31e-01 | 100.0% | 37.2% |
| 3567079 | 5.1.2.2 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › WD40 | 0.55 | 43.0 | 2.84e-01 | 84.3% | 77.1% |
| 5019170 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.55 | 49.0 | 3.70e-01 | 98.0% | 45.2% |
| 3668896 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.55 | 44.0 | 2.63e-01 | 94.1% | 11.3% |
| 3928361 | 220.1.1.46 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_14 | 0.55 | 48.0 | 3.54e-01 | 100.0% | 70.0% |
| 3643227 | 220.1.1.36 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_12 | 0.55 | 48.0 | 3.46e-01 | 100.0% | 51.3% |
| 4967607 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.55 | 34.0 | 2.53e-01 | 94.1% | 20.0% |
| 5031325 | 246.2.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos | 0.54 | 47.0 | 2.96e-01 | 100.0% | 50.2% |
| 5051446 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 41.0 | 3.07e-01 | 96.1% | 31.4% |
| 4024720 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.54 | 46.0 | 3.20e-01 | 100.0% | 63.7% |
| 3828657 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 46.0 | 3.74e-01 | 98.0% | 65.0% |
| 4997629 | 298.1.1.24 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 | 0.54 | 43.0 | 2.99e-01 | 90.2% | 71.9% |
| 4953042 | 2.14.1.1 ↗ | beta barrels › OB-fold › HupF/HypC-like › HupF/HypC-like › HupF_HypC | 0.53 | 41.0 | 3.74e-01 | 98.0% | 60.0% |
| 3901202 | 4.1.1.1 ↗ | beta barrels › SH3 › SH3 › SH3 › SH3_1 | 0.53 | 32.0 | 3.46e-01 | 74.5% | 72.5% |
| 4368436 | 5.1.4.12 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Sema | 0.53 | 40.0 | 2.61e-01 | 88.2% | 74.2% |
| 3649351 | 4337.1.1.0 ↗ | a+b two layers › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain | 0.53 | 44.0 | 3.85e-01 | 98.0% | 75.3% |
| 3255448 | 224.1.1.2 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin | 0.53 | 47.0 | 3.59e-01 | 100.0% | 85.8% |
| 3214149 | 4.1.1.92 ↗ | beta barrels › SH3 › SH3 › SH3 › SH3_9 | 0.53 | 32.0 | 3.01e-01 | 74.5% | 44.6% |
| 4964968 | 192.2.1.88 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › NFACT_N | 0.52 | 40.0 | 2.87e-01 | 86.3% | 61.9% |
| 4969344 | 4337.1.1.0 ↗ | a+b two layers › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain › DNA mismatch repair protein MutL dimerization subdomain | 0.52 | 41.0 | 3.44e-01 | 96.1% | 78.1% |
| 3356732 | 2.1.1.67 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ten1_2 | 0.52 | 41.0 | 3.34e-01 | 98.0% | 51.7% |
| 4962106 | 2.4.1.2 ↗ | beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 | 0.52 | 41.0 | 3.29e-01 | 98.0% | 95.2% |
| 4169657 | 4.1.1.175 ↗ | beta barrels › SH3 › SH3 › SH3 › MSSS | 0.51 | 36.0 | 3.66e-01 | 76.5% | 88.0% |
| 4392322 | 3239.1.1.1 ↗ | alpha complex topology › Cas1 › Cas1 › Cas1 › Cas_Cas1 | 0.51 | 44.0 | 2.76e-01 | 100.0% | 83.0% |
| 3929049 | 219.1.1.80 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF4796_C | 0.50 | 36.0 | 3.14e-01 | 78.4% | 82.4% |
D3
medium
residues 52-153
Domain cluster:
rep: MG592441.1__AUR84696.1__NVP1063O_029__00029__D2-109
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF13392.13 best | HNH_3 | 33.7 | 2.90e-08 | 42.2% | 97.8% |
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2jmkA00 | 3.30.420.600 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Thermoplasma acidophilum protein TA0956 | 0.60 | 34.0 | 3.38e-01 | 80.4% | 51.8% |
| 1a73A00 | 3.90.75.10 | Alpha Beta › Alpha-Beta Complex › Homing Intron 3 (I-Ppo) Encoded Endonuclease; Chain A › Homing Intron 3 (I-ppo) Encoded Endonuclease; Chain A | 0.55 | 50.0 | 4.26e-01 | 99.0% | 82.1% |
| 5muaB01 | 2.80.10.50 | Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › | 0.52 | 37.0 | 3.37e-01 | 74.5% | 89.8% |
| 3u4vA00 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.51 | 34.0 | 3.31e-01 | 85.3% | 59.5% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3539740 | 378.1.1.19 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_3 | 0.81 | 72.0 | 6.63e-01 | 93.1% | 86.4% |
| 3586841 | 378.1.1.7 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › NUMOD4,HNH_3 | 0.73 | 54.0 | 5.20e-01 | 77.5% | 89.6% |
| 419 | 2.4.1.1 ↗ | beta barrels › OB-fold › MOP-like › MOP-like › TOBE | 0.68 | 34.0 | 3.86e-01 | 75.5% | 63.2% |
| 3965202 | 378.1.1.19 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › HNH_3 | 0.60 | 55.0 | 5.33e-01 | 95.1% | 90.9% |
| 4347147 | 2.1.1.57 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N | 0.57 | 32.0 | 3.60e-01 | 80.4% | 71.2% |
| 5055480 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.56 | 29.0 | 3.27e-01 | 77.5% | 64.0% |
| 4373832 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.56 | 34.0 | 3.43e-01 | 84.3% | 59.0% |
| 3826195 | 2.1.1.130 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 | 0.55 | 34.0 | 3.45e-01 | 81.4% | 62.0% |
| 4277745 | 2.1.1.57 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RecO_N | 0.55 | 32.0 | 3.54e-01 | 80.4% | 72.5% |
| 3711293 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.54 | 28.0 | 3.38e-01 | 77.5% | 76.9% |
| 4936782 | 80.1.1.1 ↗ | beta complex topology › HesB-like domain › HesB-like domain › HesB-like domain › Fe-S_biosyn | 0.53 | 31.0 | 3.08e-01 | 92.2% | 53.3% |
| 3490309 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.52 | 33.0 | 2.99e-01 | 81.4% | 48.1% |
| 3476170 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.50 | 33.0 | 3.16e-01 | 84.3% | 58.3% |