Back to structures

term1_stool_scaffold_19_prodigal-single.1__X__X__00096

Bact-Vir

term1_stool_scaffold_19_prodigal-single.1__X__X__00096

Identity

Kingdom:
phage

Quality

88.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-176
PDB
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1jmxA02 2.40.128.120 Mainly Beta › Beta Barrel › Lipocalin › Quinohemoprotein amine dehydrogenase alpha subunit, domain 2 0.58 34.0 4.15e-01 91.4% 91.7%
1pbyA02 2.40.128.120 Mainly Beta › Beta Barrel › Lipocalin › Quinohemoprotein amine dehydrogenase alpha subunit, domain 2 0.55 31.0 3.86e-01 92.0% 89.6%
2w7qB00 2.50.20.10 Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX 0.55 47.0 4.71e-01 100.0% 89.4%
2lepA00 3.30.70.2350 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 18.0 2.99e-01 85.1% 82.5%
2rgnB02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.52 25.0 2.99e-01 89.7% 65.0%
8es5A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 31.0 3.40e-01 85.1% 73.9%
5ee2A00 2.40.160.90 Mainly Beta › Beta Barrel › Porin › 0.50 33.0 3.82e-01 94.9% 93.4%
6gbuD00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.50 21.0 3.15e-01 89.1% 98.4%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4995507 243.6.1.1 a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain › DUF1947 0.59 21.0 3.11e-01 86.9% 70.7%
2631766 3894.1.1.1 beta meanders › O-GlcNAc transferase GtfA beta-meander domain › O-GlcNAc transferase GtfA beta-meander domain › O-GlcNAc transferase GtfA beta-meander domain › Asp1 0.55 23.0 2.71e-01 99.4% 50.8%
4879580 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.55 44.0 4.67e-01 97.1% 96.1%
3386839 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.54 42.0 4.40e-01 99.4% 89.3%
3964807 9.7.1.2 beta barrels › Lipocalins/Streptavidin › Metalloprotease inhibitor › Metalloprotease inhibitor › PF28291 0.54 30.0 3.90e-01 89.1% 98.9%
3838812 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.54 42.0 4.45e-01 100.0% 91.2%
4115428 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.53 45.0 4.51e-01 100.0% 89.4%
3965943 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.53 46.0 4.47e-01 100.0% 86.0%
4133228 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.52 45.0 4.44e-01 100.0% 88.6%
4309203 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.52 44.0 4.43e-01 99.4% 90.0%
4285166 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.51 45.0 4.39e-01 100.0% 86.5%
4598953 12.1.1.0 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.51 24.0 2.92e-01 100.0% 67.6%
4123780 71.1.1.2 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA 0.51 45.0 4.37e-01 100.0% 87.6%
3056895 71.1.1.7 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA_2 0.50 44.0 4.30e-01 100.0% 87.4%
4965937 11.1.1.1419 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Fn3_arc 0.50 27.0 3.57e-01 92.0% 100.0%
D2 high residues 866-956
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.62 52.0 4.20e-01 100.0% 47.2%
2ccyA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.60 50.0 4.51e-01 92.3% 92.9%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 44.0 4.60e-01 80.2% 95.2%
1sdiA00 1.10.3890.10 Mainly Alpha › Orthogonal Bundle › YcfC-like › HflD-like 0.58 51.0 3.94e-01 100.0% 78.4%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.58 47.0 4.82e-01 100.0% 94.3%
2yinA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.56 46.0 4.11e-01 89.0% 92.2%
6bldA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.56 46.0 3.01e-01 91.2% 57.5%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 46.0 4.40e-01 97.8% 79.2%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.55 46.0 4.53e-01 92.3% 100.0%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 44.0 4.16e-01 89.0% 85.7%
3nynA03 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.55 41.0 4.30e-01 85.7% 92.6%
1b48A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 48.0 4.54e-01 97.8% 81.7%
3cuxA02 1.20.1220.12 Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III 0.54 46.0 4.21e-01 95.6% 98.3%
4pxoA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 47.0 4.19e-01 97.8% 73.3%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.53 46.0 4.17e-01 95.6% 76.8%
3nf4A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.53 39.0 3.68e-01 80.2% 96.6%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 44.0 3.70e-01 91.2% 87.3%
1qhhA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 33.0 2.82e-01 93.4% 34.1%
4ofzA01 1.20.58.1800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 46.0 4.33e-01 97.8% 85.8%
3ln6A01 3.30.590.20 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › 0.52 46.0 2.99e-01 100.0% 52.3%
5xdcB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.52 38.0 3.63e-01 79.1% 100.0%
6z0fA02 1.25.40.680 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type VII secretion system EssB, C-terminal-like domain 0.52 41.0 3.45e-01 91.2% 48.2%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.51 43.0 4.44e-01 100.0% 100.0%
3hgtA00 3.40.50.12360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 42.0 3.05e-01 93.4% 93.0%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4946612 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.63 52.0 4.86e-01 91.2% 93.9%
3176286 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 52.0 3.97e-01 92.3% 61.4%
2992201 6171.1.1.1 alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › JHD 0.59 45.0 4.27e-01 82.4% 76.4%
4025845 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.59 44.0 3.37e-01 78.0% 78.1%
3228669 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.58 48.0 4.00e-01 92.3% 72.7%
3954514 604.5.1.61 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PF30641 0.58 51.0 5.00e-01 100.0% 89.8%
4343245 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.57 43.0 3.98e-01 82.4% 79.2%
3801950 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.57 47.0 3.68e-01 91.2% 42.0%
3494082 109.4.1.464 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exportin-T 0.57 49.0 3.59e-01 96.7% 48.1%
3764093 6171.1.1.1 alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › JHD 0.57 49.0 4.83e-01 100.0% 89.5%
4200315 604.6.1.59 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › PigN 0.56 50.0 4.39e-01 100.0% 69.6%
3284612 604.10.1.10 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PF30641 0.56 49.0 4.81e-01 100.0% 89.0%
3272245 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.56 50.0 3.59e-01 100.0% 79.3%
3768971 192.29.1.11 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA 0.55 45.0 4.30e-01 91.2% 90.0%
3533886 109.4.1.1635 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26779 0.55 45.0 3.94e-01 91.2% 82.9%
4943811 3883.1.1.0 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain 0.55 42.0 3.32e-01 96.7% 37.6%
3408177 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 44.0 3.84e-01 90.1% 67.1%
3888027 109.4.1.1635 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26779 0.54 42.0 3.52e-01 86.8% 79.4%
3401878 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.53 42.0 3.28e-01 87.9% 75.8%
3231735 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.53 41.0 3.25e-01 82.4% 61.6%
4477679 604.27.1.1 alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac › Endotoxin_C2 0.52 45.0 4.38e-01 100.0% 84.8%
3534307 601.1.1.98 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PF27524 0.52 44.0 3.87e-01 96.7% 66.9%
3909447 601.1.2.63 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R 0.51 44.0 4.01e-01 98.9% 73.6%
1718749 109.4.1.1798 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3, TPR_8, TPR_12, TPR_16, TTC7_N 0.50 42.0 2.59e-01 97.8% 25.0%
D3 high residues 979-1070
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4q7fA01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.62 46.0 3.22e-01 78.3% 61.3%
4uhiA01 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.59 42.0 2.69e-01 72.8% 86.2%
3czhA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.59 44.0 2.78e-01 77.2% 84.1%
3wuyA00 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.59 44.0 3.14e-01 80.4% 59.9%
8e83B01 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.59 41.0 2.65e-01 72.8% 82.5%
3ejbB01 3.30.43.20 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › 0.58 37.0 3.83e-01 84.8% 69.9%
1bvyB00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.57 41.0 2.65e-01 75.0% 85.6%
1s3lA00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.57 42.0 3.52e-01 79.3% 52.7%
2q5iA03 3.40.50.800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain 0.56 37.0 3.46e-01 94.6% 52.1%
2gb7D00 3.40.91.80 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.56 42.0 3.00e-01 80.4% 61.0%
4axsA00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.56 41.0 2.91e-01 77.2% 90.4%
2i4lA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.56 42.0 2.96e-01 83.7% 65.9%
6l4lA01 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.55 39.0 3.62e-01 73.9% 99.1%
3bfmA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.54 44.0 3.72e-01 93.5% 88.3%
2kknA00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.54 41.0 3.52e-01 81.5% 65.6%
3h4rA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.54 38.0 2.95e-01 73.9% 50.2%
5khaB01 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.52 38.0 2.88e-01 79.3% 51.9%
1htwA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 38.0 3.24e-01 77.2% 72.8%
2qb7B02 3.10.310.20 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain 0.52 43.0 3.88e-01 96.7% 95.7%
2az4A01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.52 37.0 2.77e-01 77.2% 86.3%
8dvhB01 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.51 37.0 3.01e-01 76.1% 89.4%
2qsfA04 3.30.70.2460 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Rad4, beta-hairpin domain BHD3 0.51 34.0 3.78e-01 73.9% 90.0%
2edmA00 2.60.40.2770 Mainly Beta › Sandwich › Immunoglobulin-like › WSSV envelope protein-like 0.50 39.0 3.37e-01 87.0% 67.1%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4056470 3585.1.1.1 a+b two layers › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA_pol_IIIA_C 0.78 54.0 5.73e-01 70.7% 90.0%
3263231 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.63 47.0 3.45e-01 79.3% 70.8%
4435772 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.59 51.0 4.67e-01 97.8% 100.0%
5064873 246.1.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase 0.59 45.0 3.21e-01 81.5% 66.7%
5029060 246.3.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.58 43.0 3.34e-01 80.4% 64.1%
5009813 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.58 41.0 3.29e-01 76.1% 67.2%
3620960 2008.1.1.147 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF29557 0.57 40.0 2.72e-01 72.8% 66.0%
5024737 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.57 41.0 3.46e-01 76.1% 66.3%
3703066 246.3.1.0 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like 0.57 42.0 3.29e-01 80.4% 77.3%
4946846 2008.1.1.4 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 0.56 38.0 3.17e-01 70.7% 43.0%
5028297 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.56 46.0 4.26e-01 93.5% 100.0%
4175432 246.1.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase 0.56 42.0 3.05e-01 82.6% 64.6%
4280402 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.55 47.0 4.20e-01 96.7% 99.3%
4041870 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.55 47.0 4.35e-01 95.7% 100.0%
4672117 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.55 46.0 4.22e-01 94.6% 100.0%
5080291 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.55 45.0 4.24e-01 91.3% 100.0%
4628908 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.55 46.0 4.22e-01 96.7% 100.0%
3453900 246.1.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Carbon-nitrogen hydrolase › Carbon-nitrogen hydrolase › CN_hydrolase 0.55 43.0 3.01e-01 85.9% 63.4%
3582144 2008.2.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like 0.55 39.0 3.71e-01 73.9% 88.9%
5029885 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.54 45.0 4.26e-01 95.7% 100.0%
3956851 3785.1.1.0 a+b three layers › Suppressor of Fused, C-terminal domain › Suppressor of Fused, C-terminal domain › Suppressor of Fused, C-terminal domain 0.54 40.0 3.69e-01 76.1% 72.2%
3954346 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.54 41.0 2.91e-01 80.4% 96.9%
4122987 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.54 45.0 4.24e-01 96.7% 100.0%
4948107 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.54 44.0 4.15e-01 94.6% 100.0%
4086119 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.54 45.0 4.20e-01 96.7% 100.0%
4183414 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.53 44.0 4.10e-01 93.5% 99.2%
3799509 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.53 37.0 2.85e-01 70.7% 77.1%
5063520 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.53 45.0 4.29e-01 97.8% 99.1%
4217008 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.53 45.0 4.09e-01 97.8% 98.5%
4279209 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.53 45.0 4.15e-01 97.8% 100.0%
4298327 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.53 44.0 4.06e-01 95.7% 100.0%
4966826 2008.1.1.16 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.52 38.0 3.53e-01 75.0% 72.2%
4669968 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.52 41.0 3.86e-01 85.9% 78.8%
4449296 2004.1.1.84 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TsaE 0.52 38.0 3.42e-01 78.3% 81.5%
3969876 2006.1.6.15 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58 0.52 37.0 2.78e-01 73.9% 93.9%
4411782 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.52 44.0 4.17e-01 96.7% 100.0%
D4 medium residues 213-341
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01612.27 best DNA_pol_A_exo1 26.3 8.60e-06 91.5% 56.1%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1d8yA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.88 77.0 6.25e-01 96.1% 53.5%
7r0kB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.83 71.0 5.55e-01 93.0% 46.0%
7sxqA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 68.0 5.32e-01 99.2% 45.2%
6vddD01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 60.0 5.31e-01 91.5% 54.9%
2e6mA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 67.0 5.86e-01 100.0% 61.3%
7pbkA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.79 59.0 4.82e-01 96.1% 44.6%
2a1rB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 68.0 5.08e-01 91.5% 67.8%
2d5rA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.77 68.0 5.33e-01 93.0% 73.0%
1uocB00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.74 67.0 5.31e-01 96.9% 70.9%
1j54A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.73 54.0 4.82e-01 76.0% 70.7%
1vk0A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 65.0 5.52e-01 98.4% 61.5%
1s5jA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 53.0 4.56e-01 76.0% 67.5%
1noyB02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.70 52.0 4.24e-01 76.0% 69.9%
7wrnA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.69 50.0 4.31e-01 76.0% 67.2%
3iayA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.69 51.0 4.28e-01 77.5% 70.4%
4okeA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.65 48.0 4.42e-01 76.0% 74.4%
2gx9A00 3.30.420.330 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Influenza virus non-structural protein, effector domain 0.53 42.0 4.26e-01 90.7% 86.5%
4g4sP00 3.40.50.10900 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PAC-like subunit 0.51 36.0 3.13e-01 71.3% 90.0%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4975018 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.90 68.0 5.74e-01 90.7% 51.3%
3163747 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.89 77.0 4.94e-01 96.1% 23.5%
3965745 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.89 79.0 5.88e-01 96.9% 42.9%
4165451 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.88 79.0 6.17e-01 100.0% 49.0%
3980678 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 79.0 5.56e-01 98.4% 35.8%
4233346 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.86 77.0 5.47e-01 100.0% 36.1%
2469642 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.86 66.0 5.44e-01 93.8% 48.8%
4995738 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 78.0 6.33e-01 96.9% 56.4%
4037090 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.84 75.0 6.12e-01 100.0% 55.0%
4821698 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.83 74.0 7.08e-01 96.1% 82.9%
3388110 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.82 75.0 5.39e-01 99.2% 37.3%
4029824 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 68.0 5.11e-01 99.2% 40.0%
4821686 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.81 69.0 7.31e-01 90.7% 100.0%
2579558 2484.1.1.96 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_polI_exo1 0.80 66.0 5.54e-01 100.0% 55.0%
3956762 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 67.0 5.58e-01 100.0% 54.3%
160349 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.79 68.0 5.87e-01 100.0% 60.3%
3803681 2484.1.1.45 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.79 72.0 5.29e-01 96.9% 67.9%
3283743 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.79 66.0 4.78e-01 100.0% 34.0%
3266621 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 70.0 6.39e-01 93.8% 81.8%
3242153 2484.1.1.45 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.79 72.0 5.05e-01 96.9% 53.4%
3990932 2484.1.1.45 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.78 71.0 5.32e-01 96.9% 69.3%
3894412 2484.1.1.45 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 0.78 68.0 4.88e-01 91.5% 65.3%
3261268 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.78 70.0 4.81e-01 93.8% 31.7%
2810987 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.78 59.0 5.00e-01 96.9% 50.2%
3407164 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.78 68.0 5.55e-01 96.1% 53.6%
3817603 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.77 73.0 4.82e-01 100.0% 29.8%
3685910 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 68.0 5.66e-01 100.0% 57.2%
3892440 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 67.0 5.32e-01 93.8% 51.0%
3580193 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 64.0 5.39e-01 96.9% 56.1%
3656569 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.75 64.0 5.35e-01 98.4% 55.2%
5000651 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.75 56.0 3.92e-01 78.3% 69.0%
3428835 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.74 67.0 5.38e-01 97.7% 68.8%
3528675 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.73 68.0 5.49e-01 100.0% 56.2%
3368406 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.73 66.0 5.67e-01 100.0% 63.6%
4603831 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.73 66.0 5.26e-01 100.0% 51.0%
4929239 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.73 54.0 3.97e-01 77.5% 56.3%
4672299 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.72 54.0 4.67e-01 77.5% 64.9%
3357118 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 64.0 5.46e-01 98.4% 61.0%
5016375 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.72 53.0 4.56e-01 76.0% 60.0%
3664145 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.71 65.0 5.51e-01 98.4% 61.5%
3961715 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 67.0 5.89e-01 100.0% 82.8%
4649118 2484.1.1.197 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.70 53.0 3.67e-01 78.3% 69.1%
4959338 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.69 52.0 4.52e-01 76.7% 70.8%
4022366 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 51.0 3.23e-01 77.5% 23.5%
3463966 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.68 62.0 5.06e-01 98.4% 65.5%
3392123 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.68 51.0 4.24e-01 77.5% 57.1%
4932453 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.68 50.0 3.72e-01 77.5% 50.6%
5056578 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.68 51.0 3.85e-01 78.3% 53.6%
3482008 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.68 51.0 4.10e-01 77.5% 63.0%
5023018 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.67 50.0 4.25e-01 77.5% 68.6%
4504110 2484.1.1.197 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.67 51.0 3.48e-01 78.3% 62.9%
4505558 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.67 49.0 4.19e-01 76.7% 64.9%
3555725 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.66 57.0 3.95e-01 92.2% 36.9%
3766382 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.66 56.0 4.48e-01 91.5% 58.8%
5051934 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.66 56.0 4.59e-01 89.9% 64.4%
3742269 2484.1.1.90 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDDh_C 0.66 49.0 4.21e-01 77.5% 56.5%
5035328 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.65 48.0 3.93e-01 77.5% 52.8%
3951189 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.64 48.0 3.88e-01 77.5% 47.8%
3610983 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.63 47.0 3.57e-01 76.7% 39.7%
4629102 2484.1.1.36 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.59 44.0 2.97e-01 76.7% 28.3%
3273761 2011.2.1.7 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC2 0.51 37.0 2.89e-01 73.6% 91.9%
4971322 2484.3.1.1 mixed a+b and a/b › Ribonuclease H-like › Creatinase/prolidase N-terminal domain › Creatinase/prolidase N-terminal domain › Creatinase_N 0.51 44.0 4.19e-01 95.3% 92.3%
4945376 2484.3.1.7 mixed a+b and a/b › Ribonuclease H-like › Creatinase/prolidase N-terminal domain › Creatinase/prolidase N-terminal domain › Peptidase_M24 0.51 44.0 4.29e-01 96.1% 95.2%
3223923 7579.1.1.5 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S10 0.50 42.0 2.35e-01 92.2% 92.6%
D5 medium residues 449-569
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6vddA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.88 79.0 8.10e-01 100.0% 98.3%
1bdp002 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.86 73.0 7.70e-01 100.0% 99.1%
1t7pA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.78 70.0 6.36e-01 95.0% 100.0%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.72 41.0 4.66e-01 93.4% 71.9%
1bbhA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.72 38.0 3.74e-01 95.0% 47.3%
7r0kA01 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.71 58.0 6.08e-01 86.0% 100.0%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.67 39.0 4.20e-01 95.9% 68.0%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 41.0 4.27e-01 99.2% 72.7%
1n4kA02 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.61 35.0 3.26e-01 90.9% 46.6%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 34.0 3.22e-01 98.3% 48.3%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 32.0 3.09e-01 90.9% 44.4%
4lmoA00 1.10.132.70 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.57 47.0 3.79e-01 90.9% 97.6%
1mn8D00 1.10.150.180 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Gamma-retroviral matrix domain 0.54 36.0 3.92e-01 72.7% 82.5%
6srbA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 28.0 2.99e-01 90.9% 53.2%
1yowA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.53 42.0 3.45e-01 90.9% 45.2%
5af7B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 45.0 4.21e-01 90.9% 96.6%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.53 44.0 4.61e-01 89.3% 97.3%
3mk7A00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.53 46.0 3.05e-01 94.2% 98.3%
2dfkC01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.52 44.0 3.70e-01 94.2% 76.9%
7d3uC01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 32.0 3.44e-01 92.6% 72.0%
1xjuA00 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.50 35.0 3.26e-01 71.1% 98.1%
1rp3G02 1.20.140.160 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain 0.50 34.0 3.24e-01 86.8% 58.5%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3163747 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.92 83.0 5.29e-01 100.0% 23.3%
4848449 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.91 68.0 6.95e-01 87.6% 79.5%
4319500 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.90 82.0 5.28e-01 100.0% 24.0%
4061480 2484.1.1.58 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Taq-exonuc 0.90 82.0 5.76e-01 100.0% 34.8%
3580212 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.90 69.0 7.74e-01 85.1% 100.0%
4339694 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.90 80.0 5.19e-01 100.0% 24.3%
4072515 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.89 81.0 5.36e-01 100.0% 27.4%
3964115 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.89 80.0 7.79e-01 97.5% 86.9%
1391185 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.89 79.0 6.72e-01 100.0% 61.1%
57665 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.88 80.0 6.90e-01 100.0% 64.6%
3274000 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.86 82.0 6.86e-01 100.0% 91.1%
3333792 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.85 81.0 6.97e-01 100.0% 68.6%
3595357 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.85 81.0 6.92e-01 100.0% 72.2%
3676005 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.85 80.0 5.35e-01 100.0% 30.0%
3616267 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.85 81.0 7.05e-01 100.0% 74.1%
3505184 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.83 80.0 6.10e-01 100.0% 54.3%
3555725 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.83 77.0 5.16e-01 100.0% 28.7%
2970331 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.82 78.0 6.74e-01 100.0% 74.4%
1503978 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.82 76.0 6.33e-01 100.0% 61.0%
3211911 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.81 77.0 6.81e-01 100.0% 79.4%
3483300 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.79 74.0 5.93e-01 99.2% 70.0%
3407160 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.78 72.0 6.59e-01 100.0% 78.0%
4027632 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.77 71.0 7.18e-01 95.9% 96.7%
2810986 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.76 71.0 6.03e-01 100.0% 65.2%
4032335 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.73 68.0 5.74e-01 100.0% 63.7%
4024559 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.72 67.0 5.82e-01 100.0% 71.3%
3598489 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.69 64.0 5.88e-01 100.0% 78.7%
3916642 192.2.1.56 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF9 0.67 45.0 4.18e-01 95.9% 55.3%
3728304 604.12.1.24 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6604 0.59 37.0 4.03e-01 92.6% 75.0%
3990094 5086.1.1.94 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD 0.55 40.0 3.56e-01 92.6% 53.5%
3499191 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 49.0 4.57e-01 98.3% 76.7%
3215086 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.55 42.0 3.38e-01 81.8% 77.1%
4352465 632.5.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylocoagulase › Staphylocoagulase › Coagulase 0.51 38.0 3.63e-01 85.1% 66.4%
4025303 3860.1.1.155 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › RIFIN 0.50 38.0 3.13e-01 78.5% 57.1%
D6 medium residues 625-751
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 69.9 2.80e-19 98.4% 27.3%