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term1_stool_scaffold_19_prodigal-single.1__X__X__00193

Bact-Vir

term1_stool_scaffold_19_prodigal-single.1__X__X__00193

Identity

Kingdom:
phage

Quality

63.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 297-395
PDB
Domain cluster: representative
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.85 61.0 6.38e-01 73.7% 80.2%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.84 62.0 5.25e-01 75.8% 52.3%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.80 61.0 6.04e-01 88.9% 75.0%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 59.0 5.01e-01 79.8% 50.0%
4fppB01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.78 53.0 6.21e-01 100.0% 98.6%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.77 56.0 4.94e-01 88.9% 54.4%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.77 58.0 5.14e-01 77.8% 88.9%
1jkvA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.77 61.0 4.73e-01 82.8% 84.8%
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.76 67.0 5.40e-01 94.9% 78.9%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.75 62.0 5.06e-01 85.9% 89.9%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 57.0 4.86e-01 78.8% 84.7%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 56.0 4.99e-01 79.8% 90.5%
4w6vA00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.74 59.0 3.73e-01 85.9% 85.7%
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.74 59.0 4.79e-01 84.8% 90.4%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 62.0 5.08e-01 92.9% 74.2%
3rkoG00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 52.0 5.26e-01 83.8% 75.0%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 49.0 5.59e-01 77.8% 93.2%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.71 58.0 4.96e-01 85.9% 95.4%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.71 63.0 4.44e-01 100.0% 94.7%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.70 54.0 4.96e-01 81.8% 65.4%
8etcb01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.70 54.0 4.72e-01 81.8% 69.2%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.70 57.0 5.02e-01 85.9% 70.3%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 62.0 4.56e-01 100.0% 94.4%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.69 54.0 4.58e-01 81.8% 64.7%
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.69 53.0 4.65e-01 82.8% 58.9%
3ok8A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 58.0 4.34e-01 88.9% 76.7%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 44.0 4.96e-01 74.7% 86.7%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.67 44.0 4.08e-01 75.8% 52.4%
7eu3E01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 50.0 5.25e-01 83.8% 89.7%
8e9gK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 49.0 5.10e-01 83.8% 83.5%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 46.0 5.24e-01 100.0% 98.6%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 57.0 4.45e-01 97.0% 52.7%
3c5iA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.65 54.0 3.93e-01 89.9% 55.4%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 50.0 4.75e-01 83.8% 75.2%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 56.0 4.27e-01 92.9% 74.8%
8anqA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 55.0 4.29e-01 97.0% 61.6%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.64 50.0 3.92e-01 85.9% 82.8%
5tqbB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 52.0 3.57e-01 87.9% 44.3%
3buxB01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.62 56.0 5.12e-01 97.0% 97.7%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 59.0 4.15e-01 100.0% 67.3%
5b00A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.62 49.0 3.57e-01 82.8% 50.2%
1w33A00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.62 54.0 4.45e-01 96.0% 64.1%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 57.0 4.18e-01 99.0% 63.6%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.61 56.0 4.45e-01 99.0% 93.6%
4ehsA00 1.10.860.10 Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A 0.61 47.0 4.43e-01 83.8% 95.2%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.60 56.0 5.04e-01 100.0% 97.7%
1y6xA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.60 38.0 4.01e-01 75.8% 72.4%
8hdlA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.59 51.0 3.82e-01 93.9% 40.7%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 54.0 3.90e-01 100.0% 71.8%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.58 50.0 3.66e-01 100.0% 86.2%
7cj3A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.57 51.0 3.80e-01 100.0% 50.8%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4936497 150.1.1.14 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like 0.92 63.0 6.75e-01 72.7% 79.5%
5012651 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.87 62.0 6.71e-01 82.8% 85.9%
5034673 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.86 64.0 5.48e-01 77.8% 51.3%
3974230 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.84 63.0 6.21e-01 77.8% 84.8%
3639099 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.84 61.0 3.85e-01 74.7% 26.2%
3945517 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.82 57.0 5.82e-01 70.7% 73.7%
3985434 622.4.1.0 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.82 56.0 5.94e-01 70.7% 77.8%
3637930 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.82 67.0 4.95e-01 85.9% 78.3%
2142296 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.82 61.0 6.17e-01 76.8% 78.6%
3285654 5051.1.1.10 ↗ alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 0.81 66.0 4.15e-01 85.9% 76.0%
4950274 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.81 59.0 5.98e-01 75.8% 75.8%
3584946 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.80 66.0 4.89e-01 86.9% 40.8%
4111212 622.4.1.30 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › ETR1_N 0.80 64.0 6.42e-01 84.8% 83.0%
4987192 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.80 71.0 6.60e-01 97.0% 100.0%
4021944 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.79 64.0 4.67e-01 84.8% 95.0%
4586824 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.79 64.0 4.67e-01 83.8% 83.5%
2163536 150.1.2.8 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › MiaE 0.78 65.0 5.04e-01 87.9% 80.2%
4952530 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.78 69.0 6.23e-01 98.0% 97.0%
3640629 3843.1.1.0 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.77 61.0 5.09e-01 84.8% 53.5%
3285217 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.76 60.0 4.51e-01 83.8% 46.8%
3288395 150.1.1.12 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF4439 0.76 56.0 4.99e-01 76.8% 88.1%
3221606 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.76 61.0 5.96e-01 83.8% 100.0%
4973614 5069.1.3.26 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF1622 0.75 60.0 5.81e-01 84.8% 84.5%
4935725 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.75 68.0 6.14e-01 100.0% 91.1%
3791831 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.74 60.0 4.48e-01 84.8% 79.5%
3615987 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.73 59.0 4.31e-01 83.8% 80.4%
3996198 174.1.1.1 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.72 59.0 5.13e-01 86.9% 60.7%
3214191 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 54.0 5.12e-01 78.8% 87.8%
4119718 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.71 55.0 5.76e-01 97.0% 87.8%
3170506 4177.1.1.14 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 0.71 57.0 4.17e-01 83.8% 77.5%
4676422 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.71 53.0 4.41e-01 79.8% 92.0%
4654652 633.21.1.23 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.71 56.0 4.92e-01 82.8% 66.4%
5039649 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 61.0 5.62e-01 89.9% 88.3%
4266510 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.70 63.0 6.20e-01 93.9% 92.4%
3929729 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.70 61.0 4.73e-01 90.9% 68.7%
5081365 601.33.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.70 65.0 5.67e-01 100.0% 84.8%
4074458 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.70 62.0 6.21e-01 92.9% 95.0%
4345287 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.70 62.0 6.21e-01 92.9% 95.0%
4470423 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.70 64.0 6.01e-01 96.0% 85.2%
4617194 601.16.1.22 ↗ alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Apolipoprotein 0.70 58.0 4.86e-01 86.9% 64.5%
4541659 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.69 61.0 6.01e-01 92.9% 91.4%
4042986 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.69 60.0 6.07e-01 92.9% 95.0%
3931307 601.1.2.4 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.69 55.0 4.79e-01 83.8% 66.2%
4223425 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.69 63.0 6.21e-01 97.0% 90.5%
4032165 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.68 60.0 6.06e-01 92.9% 95.0%
4044992 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.68 60.0 5.92e-01 93.9% 93.3%
3477777 4177.1.1.12 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAM92 0.68 64.0 4.61e-01 97.0% 64.3%
3608199 1189.1.1.0 ↗ alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.68 58.0 4.60e-01 89.9% 77.8%
3479602 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.68 59.0 4.43e-01 91.9% 50.0%
3940645 633.23.1.1 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin 0.68 59.0 4.63e-01 91.9% 61.1%
4179301 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.67 59.0 5.73e-01 100.0% 83.6%
4429835 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.67 58.0 5.87e-01 92.9% 93.0%
3296913 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.66 60.0 4.98e-01 96.0% 61.9%
3453619 601.4.1.12 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B 0.66 60.0 5.12e-01 100.0% 87.7%
4304767 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.66 57.0 5.74e-01 93.9% 95.0%
3633897 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 59.0 4.75e-01 96.0% 83.7%
3214864 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 51.0 4.43e-01 83.8% 58.7%
4618995 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.65 48.0 4.86e-01 78.8% 90.0%
3574954 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.64 57.0 4.46e-01 96.0% 94.6%
4479516 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.64 58.0 5.78e-01 96.0% 95.0%
3783621 4177.1.1.14 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 0.63 58.0 3.99e-01 97.0% 67.5%
4126682 192.29.1.116 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Apolipoprotein 0.62 51.0 4.02e-01 88.9% 48.0%
3680262 611.9.1.4 ↗ alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.54 44.0 4.10e-01 89.9% 96.0%
D2 medium residues 179-253
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 64.0 5.73e-01 100.0% 97.2%
2lxlA00 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.71 61.0 4.73e-01 96.0% 77.9%
1w99A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.70 62.0 4.75e-01 100.0% 65.3%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.70 50.0 4.76e-01 76.0% 97.8%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.69 62.0 5.89e-01 100.0% 95.5%
1ya0A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 56.0 4.13e-01 98.7% 37.9%
1wjzA00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.64 45.0 4.19e-01 73.3% 74.5%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.64 54.0 4.68e-01 98.7% 65.1%
4wz0A00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.63 54.0 4.84e-01 97.3% 93.6%
2wauA02 1.20.58.830 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 52.0 4.51e-01 98.7% 96.7%
1w2yA00 1.10.4010.10 Mainly Alpha › Orthogonal Bundle › all-alpha NTP pyrophosphatase fold › Type II deoxyuridine triphosphatase 0.61 45.0 3.25e-01 80.0% 54.0%
5jjxA01 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 51.0 3.48e-01 100.0% 65.0%
2ksfA00 1.20.120.620 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd, 0.59 47.0 4.28e-01 90.7% 65.4%
4hkaA01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 47.0 3.26e-01 92.0% 82.3%
1t9kA01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.58 46.0 3.84e-01 90.7% 54.3%
2jroA01 3.30.1910.10 Alpha Beta › 2-Layer Sandwich › so0334 like fold › so0334 like domain 0.57 42.0 4.51e-01 78.7% 100.0%
7blfB01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.56 45.0 2.95e-01 92.0% 56.8%
1ps9A01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 44.0 2.89e-01 90.7% 34.8%
3oq2A00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 40.0 3.74e-01 89.3% 60.6%
4tv5A00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.54 43.0 3.04e-01 88.0% 42.9%
7tjbA01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.54 41.0 3.04e-01 84.0% 43.2%
7prrB01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.52 40.0 3.17e-01 89.3% 37.3%
2bdqA00 3.20.20.380 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Copper homeostasis (CutC) domain 0.50 39.0 2.92e-01 86.7% 34.0%
2ff4A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 37.0 3.45e-01 81.3% 73.7%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4169660 604.27.1.0 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac 0.84 70.0 7.26e-01 89.3% 98.6%
3588836 604.27.1.0 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac 0.84 76.0 5.69e-01 98.7% 81.7%
4092776 604.27.1.0 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac 0.84 71.0 7.16e-01 90.7% 95.9%
4163035 604.27.1.1 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac › Endotoxin_C2 0.82 67.0 6.60e-01 88.0% 90.0%
4345155 604.27.1.1 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac › Endotoxin_C2 0.80 70.0 7.01e-01 94.7% 94.7%
4052114 604.27.1.0 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac 0.80 66.0 6.80e-01 89.3% 97.1%
4108164 604.27.1.4 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac › Cry1Ac_D5 0.80 64.0 4.22e-01 86.7% 26.1%
4335598 604.27.1.0 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac 0.79 65.0 5.75e-01 88.0% 74.3%
4477679 604.27.1.1 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac › Endotoxin_C2 0.79 64.0 5.68e-01 86.7% 73.3%
1388531 604.27.1.0 ↗ alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac 0.78 67.0 5.95e-01 94.7% 74.8%
3505507 1134.1.1.0 ↗ alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.72 60.0 6.21e-01 89.3% 100.0%
3820599 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.72 57.0 4.27e-01 85.3% 52.8%
3214191 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 63.0 5.47e-01 98.7% 96.5%
4453346 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 49.0 3.25e-01 72.0% 66.9%
3605561 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.68 58.0 4.59e-01 98.7% 73.9%
5059668 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.68 58.0 5.28e-01 98.7% 89.5%
3893367 604.1.1.92 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_desmoplakin_3 0.67 58.0 4.50e-01 97.3% 77.0%
5000698 604.38.1.0 ↗ alpha bundles › Spectrin repeat-like › Legionella effector SdeA 3-helical bundle › Legionella effector SdeA 3-helical bundle 0.64 54.0 4.87e-01 96.0% 79.0%
3807866 109.4.1.120 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Kinetochor_Ybp2 0.63 57.0 3.53e-01 100.0% 19.5%
3656993 109.4.1.120 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Kinetochor_Ybp2 0.63 54.0 3.74e-01 100.0% 39.3%
3820927 109.4.1.109 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 0.61 55.0 3.70e-01 100.0% 32.5%
3686012 3722.1.1.0 ↗ alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain 0.61 54.0 3.95e-01 98.7% 69.8%
4024251 4984.1.1.0 ↗ alpha bundles › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain › Duffy-binding-like domain, C-terminal subdomain 0.61 45.0 3.97e-01 81.3% 88.3%
3695755 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 51.0 3.88e-01 96.0% 59.5%
3655530 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.59 51.0 4.72e-01 98.7% 79.0%
4546376 3922.1.1.276 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SMC_N, AAA_21 0.57 45.0 2.75e-01 86.7% 62.6%
5074374 2002.1.1.32 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Oxidored_FMN 0.57 45.0 2.94e-01 89.3% 42.4%
4946099 3843.1.1.0 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.55 47.0 4.61e-01 98.7% 89.2%
4022166 109.4.1.17 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin 0.54 41.0 3.70e-01 86.7% 87.0%
4982139 633.6.1.1 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.50 40.0 3.36e-01 94.7% 82.0%
D3 medium residues 254-296_396-416
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ezuA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 54.0 4.03e-01 95.3% 48.9%
2vzbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 55.0 4.09e-01 96.9% 59.9%
4r42A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 55.0 3.95e-01 96.9% 56.1%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 50.0 3.67e-01 89.1% 85.0%
2fzfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 51.0 3.90e-01 93.8% 56.7%
1xl7A01 1.10.275.20 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Choline/Carnitine o-acyltransferase 0.58 45.0 3.95e-01 85.9% 85.4%
2c2uA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 48.0 3.55e-01 95.3% 81.5%
3zssA02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.56 48.0 4.46e-01 93.8% 84.8%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 42.0 3.43e-01 90.6% 95.2%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5055566 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.64 54.0 4.56e-01 98.4% 87.8%
3707377 604.12.1.73 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF27107 0.63 47.0 3.78e-01 79.7% 73.6%
5051132 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.63 49.0 3.97e-01 87.5% 76.3%
4984330 3651.1.1.0 ↗ alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain 0.58 40.0 3.58e-01 71.9% 51.1%
3465357 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.52 45.0 3.78e-01 100.0% 83.5%