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term4_saliva_scaffold_1_prodigal-single.1__X__X__00140

Bact-Vir

term4_saliva_scaffold_1_prodigal-single.1__X__X__00140

Identity

Kingdom:
phage

Quality

86.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 13-113
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vwxA02 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.64 37.0 4.15e-01 90.1% 73.8%
1ib8A02 2.30.30.180 Mainly Beta › Roll › SH3 type barrels. › Ribosome maturation factor RimP, C-terminal domain 0.62 35.0 4.08e-01 78.2% 82.1%
2vxtI00 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.61 49.0 4.26e-01 86.1% 96.8%
5uc6A00 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.57 48.0 4.17e-01 90.1% 94.7%
4usoA00 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.57 45.0 4.14e-01 86.1% 97.1%
1nycA00 2.40.310.10 Mainly Beta › Beta Barrel › Staphostatins › beta-Barrel protease inhibitors 0.57 40.0 3.94e-01 73.3% 91.0%
1f39A00 2.10.109.10 Mainly Beta › Ribbon › Umud Fragment, subunit A › Umud Fragment, subunit A 0.55 32.0 3.30e-01 99.0% 57.4%
2k3dA00 3.10.450.130 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › folded 79 residue fragment of lin0334 like domains 0.55 39.0 4.12e-01 73.3% 85.1%
1cbiA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 40.0 3.65e-01 78.2% 96.3%
1r8nA00 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.54 43.0 3.62e-01 88.1% 90.8%
1yemB00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.53 38.0 3.29e-01 75.2% 97.0%
7dpyB01 2.40.128.200 Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor 0.53 40.0 4.30e-01 90.1% 96.4%
1oh1A00 2.40.310.10 Mainly Beta › Beta Barrel › Staphostatins › beta-Barrel protease inhibitors 0.53 37.0 3.67e-01 72.3% 88.1%
3v0rA01 2.40.350.20 Mainly Beta › Beta Barrel › AOC barrel-like › 0.53 39.0 3.73e-01 78.2% 94.2%
6cz4A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 32.0 3.45e-01 80.2% 70.9%
4hwmA00 2.40.128.500 Mainly Beta › Beta Barrel › Lipocalin › YedD-like protein 0.52 41.0 3.94e-01 87.1% 72.6%
5a67A00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.52 43.0 3.53e-01 94.1% 81.1%
7szeB02 3.90.380.10 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 0.51 39.0 3.25e-01 81.2% 81.5%
3cxjA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.51 36.0 3.21e-01 74.3% 77.8%
1x99A00 2.60.270.20 Mainly Beta › Sandwich › Mutm (Fpg) Protein; Chain: A, domain 2 › Cytolysin/lectin 0.50 35.0 3.17e-01 72.3% 92.4%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4937423 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.69 49.0 5.32e-01 85.1% 88.2%
3172078 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.68 43.0 3.19e-01 79.2% 26.7%
4675879 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.66 43.0 3.14e-01 79.2% 25.3%
3781145 239.3.1.0 ↗ beta barrels › Ribosomal protein L25-like › FAS1 domain › FAS1 domain 0.63 48.0 4.07e-01 81.2% 70.3%
3843359 4.1.1.246 ↗ beta barrels › SH3 › SH3 › SH3 › Tudor_Coilin 0.62 41.0 4.45e-01 85.1% 80.0%
3214782 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.58 40.0 3.76e-01 70.3% 100.0%
3214867 207.1.1.81 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.58 41.0 2.96e-01 73.3% 43.4%
3222053 2484.1.1.200 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FTH 0.58 40.0 3.06e-01 70.3% 51.6%
None — 0.58 43.0 3.38e-01 80.2% 67.1%
4216985 331.19.1.2 ↗ a+b two layers › TBP-like › Toxin RnlA N-terminal domains › Toxin RnlA N-terminal domains › RnlA_toxin_N 0.57 38.0 4.12e-01 72.3% 82.4%
4013671 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.57 31.0 4.09e-01 75.2% 100.0%
3214007 145.1.1.1 ↗ alpha arrays › F-box domain › F-box domain › F-box domain › F-box 0.57 39.0 3.69e-01 71.3% 99.2%
868 9.6.1.2 ↗ beta barrels › Lipocalins/Streptavidin › Staphostatin › Staphostatin › Staphostatin_B 0.57 40.0 3.94e-01 73.3% 91.0%
3852438 883.1.1.24 ↗ a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › PF29321 0.56 41.0 3.42e-01 77.2% 55.0%
3935730 241.10.1.1 ↗ a+b two layers › Type III secretory system chaperone-like › GAS2 domain › GAS2 domain › GAS2 0.55 41.0 4.33e-01 100.0% 86.7%
3948079 9.1.1.4 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › META 0.55 44.0 4.17e-01 87.1% 93.3%
4677426 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.54 41.0 3.26e-01 78.2% 90.0%
3700781 3794.1.1.0 ↗ a+b two layers › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Methylcrotonyl-CoA carboxylase alpha-subunit BT domain-related › Barrel domain in methylcrotonyl-CoA carboxylase alpha-subunit 0.53 40.0 3.70e-01 79.2% 83.8%
3736787 331.3.1.2 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Ring_hydroxyl_A 0.53 41.0 2.97e-01 81.2% 90.9%
3286115 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.53 38.0 3.64e-01 74.3% 71.3%
4168024 6.1.1.0 ↗ beta duplicates or obligate multimers › beta-Trefoil › beta-Trefoil › beta-Trefoil 0.53 41.0 3.69e-01 84.2% 95.7%
5059099 241.2.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › Frataxin-like › Frataxin-like 0.52 37.0 3.89e-01 94.1% 84.1%
3931011 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.51 39.0 3.63e-01 83.2% 93.8%
3337354 719.1.1.0 ↗ beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain 0.51 36.0 3.36e-01 74.3% 79.2%
D2 high residues 216-289
PDB
Domain cluster: representative
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6bogA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.73 49.0 5.69e-01 85.1% 98.1%
3udcA02 2.30.30.60 Mainly Beta › Roll › SH3 type barrels. › 0.69 42.0 4.89e-01 85.1% 92.0%
6bhdA03 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.68 52.0 5.56e-01 89.2% 95.2%
5ajiB02 2.30.30.60 Mainly Beta › Roll › SH3 type barrels. › 0.68 42.0 4.80e-01 85.1% 92.0%
7cfdA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.68 46.0 4.65e-01 87.8% 71.2%
4ytlA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.66 42.0 4.91e-01 83.8% 98.0%
7c9rH01 3.90.50.10 Alpha Beta › Alpha-Beta Complex › Photosynthetic Reaction Center; Chain H, domain 2 › Photosynthetic Reaction Center, subunit H, domain 2 0.66 45.0 3.63e-01 71.6% 71.6%
3goxA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.65 42.0 4.91e-01 77.0% 96.1%
4c5eC02 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.64 52.0 4.69e-01 85.1% 92.7%
2do3A01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.64 40.0 4.64e-01 77.0% 92.2%
2e70A00 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.63 42.0 4.27e-01 83.8% 70.4%
5yy8A00 2.120.10.80 Mainly Beta › 6 Propeller › Neuraminidase › Kelch-type beta propeller 0.63 44.0 3.02e-01 74.3% 27.6%
4ii1A02 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.63 45.0 5.03e-01 89.2% 100.0%
2b5lB01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.63 45.0 2.85e-01 75.7% 29.6%
3h8zA02 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.63 43.0 4.55e-01 85.1% 81.2%
1b7tA02 2.30.30.360 Mainly Beta › Roll › SH3 type barrels. › Myosin S1 fragment, N-terminal 0.62 39.0 4.39e-01 78.4% 88.5%
3htyA00 2.40.128.280 Mainly Beta › Beta Barrel › Lipocalin › 0.62 49.0 4.63e-01 90.5% 98.9%
2eqjA00 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.62 43.0 4.53e-01 87.8% 81.8%
1jmxB00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.61 46.0 3.01e-01 81.1% 39.5%
1w1hD00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 47.0 3.88e-01 83.8% 81.8%
7razA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 44.0 4.24e-01 89.2% 67.1%
3dsmA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.61 43.0 2.80e-01 74.3% 22.6%
3feoB02 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.61 49.0 4.72e-01 86.5% 95.2%
2xk0A00 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.60 45.0 4.62e-01 91.9% 84.1%
5tf2A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.60 44.0 2.85e-01 77.0% 36.1%
4j0wA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.60 42.0 2.76e-01 74.3% 30.9%
3u4yA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.59 43.0 2.88e-01 78.4% 34.8%
1jyaB00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.59 48.0 4.12e-01 89.2% 80.2%
1r5mA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.59 41.0 2.70e-01 74.3% 20.8%
2cnxA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.59 41.0 2.72e-01 73.0% 34.0%
7b9cA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.59 43.0 2.82e-01 81.1% 45.5%
2e6zA00 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.59 40.0 4.39e-01 85.1% 89.8%
1vyhC01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.58 42.0 2.84e-01 77.0% 25.6%
4lg8A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.58 41.0 2.76e-01 75.7% 34.2%
2ymsA00 2.40.128.630 Mainly Beta › Beta Barrel › Lipocalin › 0.58 41.0 3.53e-01 75.7% 83.1%
7afrX02 2.30.30.180 Mainly Beta › Roll › SH3 type barrels. › Ribosome maturation factor RimP, C-terminal domain 0.57 42.0 4.51e-01 87.8% 96.7%
3gjyA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 44.0 3.03e-01 85.1% 43.4%
4wj7D00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 42.0 3.65e-01 82.4% 94.3%
2gu3A02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 39.0 4.15e-01 74.3% 98.4%
3loyA02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 41.0 3.59e-01 78.4% 84.2%
2cudA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.55 40.0 3.95e-01 79.7% 72.2%
2in5A00 2.40.360.10 Mainly Beta › Beta Barrel › YmcC-like fold › YmcC-like 0.54 41.0 3.09e-01 83.8% 74.9%
2rqrA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.53 38.0 3.26e-01 75.7% 47.9%
1x6bA01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.53 39.0 4.14e-01 81.1% 90.6%
3ci0K01 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.53 38.0 3.47e-01 78.4% 67.3%
4q1vA01 2.140.10.30 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › Dipeptidylpeptidase IV, N-terminal domain 0.53 38.0 2.43e-01 78.4% 34.2%
1lckA01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.52 37.0 4.06e-01 79.7% 94.9%
1mg2A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 39.0 2.56e-01 83.8% 35.3%
4cvbA00 2.140.10.10 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › Quinoprotein alcohol dehydrogenase-like superfamily 0.51 38.0 2.38e-01 83.8% 33.3%
6g6qA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 39.0 3.21e-01 83.8% 72.2%
1sqhA02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.50 41.0 3.46e-01 91.9% 76.3%
2m0yA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.50 37.0 3.70e-01 82.4% 78.4%
ECOD (79)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5050433 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.82 50.0 6.13e-01 85.1% 100.0%
5042477 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.79 48.0 5.88e-01 82.4% 100.0%
4992872 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.78 52.0 5.87e-01 87.8% 92.7%
5040416 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.78 48.0 5.59e-01 85.1% 92.0%
4997767 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.77 47.0 5.66e-01 83.8% 100.0%
5033075 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.77 49.0 5.49e-01 89.2% 87.3%
5058671 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.75 49.0 5.50e-01 89.2% 89.1%
4952887 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.75 48.0 5.35e-01 86.5% 87.3%
4990212 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.75 48.0 5.42e-01 85.1% 89.1%
4946165 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.74 50.0 5.60e-01 89.2% 92.7%
4994957 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.74 49.0 5.62e-01 86.5% 92.7%
4950396 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.74 45.0 5.14e-01 86.5% 83.6%
3603357 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.74 49.0 5.56e-01 87.8% 92.7%
5017214 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.73 48.0 5.42e-01 86.5% 90.9%
5013892 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.71 49.0 5.54e-01 87.8% 96.4%
3831652 71.1.1.17 ↗ beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › PF28435 0.70 45.0 3.52e-01 70.3% 30.4%
4579331 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.70 48.0 5.19e-01 90.5% 84.1%
4947995 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.70 47.0 5.27e-01 87.8% 92.7%
3302818 4.1.1.236 ↗ beta barrels › SH3 › SH3 › SH3 › KOWx_SPT5 0.70 46.0 5.16e-01 87.8% 90.9%
5044373 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.69 48.0 5.21e-01 90.5% 88.3%
3914746 4.1.1.128 ↗ beta barrels › SH3 › SH3 › SH3 › Tudor_4 0.69 52.0 5.38e-01 89.2% 84.3%
4978125 4.1.1.13 ↗ beta barrels › SH3 › SH3 › SH3 › MS_channel_2nd 0.69 42.0 5.02e-01 79.7% 100.0%
3240406 4.1.1.347 ↗ beta barrels › SH3 › SH3 › SH3 › KOW7_SPT5, KOW6_SPT5 0.69 48.0 4.09e-01 71.6% 49.6%
5025079 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.69 46.0 5.13e-01 87.8% 92.7%
4975150 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.68 48.0 5.16e-01 89.2% 90.0%
3261235 4.1.1.9 ↗ beta barrels › SH3 › SH3 › SH3 › TUDOR 0.68 48.0 4.64e-01 86.5% 64.7%
5060760 4.1.1.13 ↗ beta barrels › SH3 › SH3 › SH3 › MS_channel_2nd 0.68 48.0 5.07e-01 87.8% 84.6%
4967397 4.1.1.13 ↗ beta barrels › SH3 › SH3 › SH3 › MS_channel_2nd 0.68 48.0 5.14e-01 89.2% 86.2%
3517728 4.1.1.43 ↗ beta barrels › SH3 › SH3 › SH3 › SMN_Tudor 0.67 46.0 4.78e-01 83.8% 75.7%
4964421 4.1.1.13 ↗ beta barrels › SH3 › SH3 › SH3 › MS_channel_2nd 0.66 46.0 4.84e-01 87.8% 81.5%
3343255 5.1.4.37 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nup160 0.65 45.0 2.74e-01 73.0% 18.2%
5049481 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.64 47.0 3.97e-01 75.7% 63.4%
4002896 4.1.1.9 ↗ beta barrels › SH3 › SH3 › SH3 › TUDOR 0.64 45.0 4.23e-01 89.2% 60.0%
3398093 4.1.1.43 ↗ beta barrels › SH3 › SH3 › SH3 › SMN_Tudor 0.64 47.0 5.12e-01 91.9% 96.7%
3300848 4.1.1.38 ↗ beta barrels › SH3 › SH3 › SH3 › Ribosomal_L2_C 0.64 40.0 3.57e-01 86.5% 44.7%
3421470 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.63 50.0 3.33e-01 89.2% 90.1%
4014269 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.63 45.0 2.80e-01 75.7% 37.7%
4980648 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.63 47.0 4.86e-01 89.2% 84.3%
3347499 5.1.10.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 12-bladed 0.63 37.0 3.79e-01 83.8% 60.0%
3883159 4.1.1.9 ↗ beta barrels › SH3 › SH3 › SH3 › TUDOR 0.63 45.0 4.21e-01 89.2% 61.1%
5036647 4.1.1.13 ↗ beta barrels › SH3 › SH3 › SH3 › MS_channel_2nd 0.63 46.0 4.71e-01 89.2% 81.4%
3840679 4.1.1.9 ↗ beta barrels › SH3 › SH3 › SH3 › TUDOR 0.63 45.0 4.12e-01 89.2% 57.9%
3728321 267.1.1.3 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase 0.63 50.0 3.46e-01 87.8% 51.5%
3715158 5.1.5.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.63 44.0 2.60e-01 74.3% 12.3%
3474731 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.62 43.0 2.52e-01 74.3% 20.0%
3761733 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.62 44.0 2.88e-01 75.7% 34.2%
3592525 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.60 53.0 4.63e-01 97.3% 89.1%
3060582 5.1.4.58 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › DUF5074 0.60 42.0 2.77e-01 74.3% 21.6%
3500244 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.60 44.0 2.80e-01 78.4% 29.3%
3707373 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.60 42.0 2.73e-01 75.7% 37.6%
3923813 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.59 48.0 5.09e-01 89.2% 100.0%
3653947 71.1.1.17 ↗ beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › PF28435 0.59 45.0 3.43e-01 82.4% 65.0%
4147983 5.1.4.126 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Striatin 0.59 41.0 2.66e-01 74.3% 32.9%
4036214 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.57 44.0 2.82e-01 85.1% 31.7%
3717633 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 45.0 2.84e-01 87.8% 49.9%
3570911 4291.1.1.1 ↗ beta barrels › Oxysterol-binding protein › Oxysterol-binding protein › Oxysterol-binding protein › Oxysterol_BP 0.57 47.0 3.14e-01 97.3% 46.9%
3999240 5.1.5.45 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › PROPPIN 0.57 43.0 3.19e-01 83.8% 44.7%
3717796 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.57 42.0 3.03e-01 81.1% 50.4%
3486202 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.56 42.0 2.68e-01 82.4% 17.2%
3716768 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.56 40.0 2.61e-01 77.0% 21.1%
3670140 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.56 43.0 3.09e-01 83.8% 44.8%
3276702 5.1.4.319 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR11_1st 0.56 44.0 2.70e-01 86.5% 24.6%
3222210 4.1.1.54 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_2 0.55 42.0 4.33e-01 82.4% 87.1%
2581407 241.14.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › SARS-unique domain-C › SARS-unique domain-C 0.54 43.0 4.26e-01 90.5% 89.7%
158943 4.1.1.1 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_1 0.53 39.0 3.86e-01 81.1% 73.4%
3998645 4.1.1.54 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_2 0.53 37.0 3.90e-01 77.0% 83.1%
3482683 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.53 36.0 3.97e-01 74.3% 90.0%
3224441 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.53 38.0 3.97e-01 82.4% 83.8%
3585799 5.1.5.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.52 40.0 2.91e-01 83.8% 57.3%
3520708 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.52 39.0 2.56e-01 82.4% 23.3%
3240651 4.1.1.1 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_1 0.52 37.0 3.67e-01 79.7% 70.0%
3479037 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.52 37.0 3.64e-01 77.0% 70.0%
3905176 4.1.1.1 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_1 0.52 38.0 4.00e-01 82.4% 89.2%
4890224 5.1.4.37 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nup160 0.51 41.0 2.58e-01 95.9% 25.1%
3455400 5.1.3.142 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Beta-prop_AT5G49610-like 0.51 43.0 2.90e-01 100.0% 45.1%
3577993 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.50 42.0 3.02e-01 98.6% 29.6%
3482646 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.50 38.0 2.79e-01 81.1% 65.0%
3404744 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.50 39.0 2.63e-01 90.5% 87.9%
4449649 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.50 41.0 2.56e-01 90.5% 96.3%
D3 medium residues 114-166_356-393
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 52.0 4.93e-01 93.4% 90.8%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.60 39.0 3.85e-01 89.0% 60.0%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.60 46.0 4.23e-01 92.3% 62.0%
2ncoA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.60 38.0 3.75e-01 97.8% 57.8%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 50.0 4.63e-01 93.4% 88.9%
4bbrM00 1.10.472.170 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › 0.59 43.0 3.35e-01 100.0% 35.8%
1w98B02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.59 44.0 4.13e-01 100.0% 64.0%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 48.0 4.66e-01 92.3% 88.2%
1nklA00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.57 36.0 3.86e-01 91.2% 73.1%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.57 48.0 4.53e-01 93.4% 91.7%
1c9bA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.56 43.0 4.09e-01 100.0% 68.9%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 47.0 4.46e-01 92.3% 85.0%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 46.0 3.84e-01 91.2% 80.4%
1aisB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.55 42.0 4.18e-01 100.0% 77.7%
1f16A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.55 39.0 3.13e-01 90.1% 35.4%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 41.0 4.38e-01 90.1% 94.7%
1vs5O00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.55 40.0 4.11e-01 91.2% 80.7%
4acoA01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.54 47.0 4.41e-01 100.0% 79.1%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.54 40.0 4.24e-01 90.1% 88.7%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 48.0 4.62e-01 97.8% 87.1%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.54 45.0 4.50e-01 91.2% 87.4%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.54 44.0 3.45e-01 91.2% 40.6%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.53 47.0 4.37e-01 98.9% 90.4%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 45.0 4.25e-01 92.3% 83.3%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.52 43.0 4.01e-01 91.2% 80.3%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.52 42.0 3.83e-01 90.1% 68.8%
2jaqA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 42.0 3.39e-01 100.0% 44.4%
ECOD (51)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5000534 601.30.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.69 58.0 4.79e-01 91.2% 65.6%
3594203 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.67 56.0 5.33e-01 90.1% 92.4%
3401839 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.64 58.0 5.09e-01 100.0% 87.4%
3484909 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 53.0 4.80e-01 91.2% 90.0%
3903775 192.8.1.419 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › PF27603 0.62 51.0 4.70e-01 90.1% 80.8%
2885155 109.21.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleopor_Nup85 0.62 54.0 3.23e-01 96.7% 14.8%
3577620 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 52.0 4.85e-01 92.3% 82.6%
3718156 101.1.9.0 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain 0.62 47.0 4.64e-01 82.4% 76.8%
4943557 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.60 54.0 4.82e-01 100.0% 86.2%
3849331 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.60 51.0 4.72e-01 92.3% 81.7%
3961527 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.60 51.0 4.38e-01 94.5% 100.0%
None — 0.60 49.0 2.96e-01 92.3% 15.4%
3896730 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 50.0 4.39e-01 91.2% 93.3%
5000678 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.59 45.0 4.38e-01 100.0% 73.0%
4553877 633.23.1.22 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.58 51.0 4.31e-01 100.0% 79.4%
3457105 601.4.1.44 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DUF3054 0.58 52.0 4.68e-01 98.9% 91.2%
3899960 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 48.0 4.67e-01 91.2% 85.0%
3900975 604.1.1.92 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_desmoplakin_3 0.58 48.0 4.31e-01 92.3% 76.9%
3483197 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 52.0 4.38e-01 100.0% 92.0%
4863092 150.3.1.28 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › GCSF 0.57 51.0 4.75e-01 100.0% 95.6%
3505438 604.1.1.67 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_5 0.57 47.0 4.64e-01 91.2% 87.0%
3712348 5057.1.1.0 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.57 49.0 3.66e-01 100.0% 71.0%
3489764 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 47.0 4.52e-01 92.3% 88.6%
3707377 604.12.1.73 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF27107 0.56 46.0 4.17e-01 90.1% 70.4%
3796191 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 47.0 4.44e-01 92.3% 78.2%
3491110 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 47.0 4.42e-01 92.3% 82.7%
3640330 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 48.0 4.19e-01 96.7% 83.6%
5045256 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 44.0 4.38e-01 91.2% 84.2%
3524429 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 45.0 4.44e-01 91.2% 86.0%
3725215 192.29.1.148 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF3433 0.55 43.0 3.63e-01 89.0% 75.3%
3217462 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 45.0 4.38e-01 91.2% 86.0%
3569538 601.1.1.52 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Yip1 0.54 47.0 3.85e-01 97.8% 76.6%
3220003 198.1.1.0 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.54 34.0 3.70e-01 92.3% 76.0%
3778551 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 45.0 4.23e-01 92.3% 87.0%
5077440 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.54 46.0 4.05e-01 95.6% 87.1%
3921192 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 44.0 4.14e-01 91.2% 91.3%
3415238 603.1.1.6 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.53 44.0 3.54e-01 92.3% 52.4%
3504302 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 44.0 4.28e-01 92.3% 89.0%
4864293 601.15.1.3 ↗ alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › BPA 0.52 36.0 3.51e-01 87.9% 62.5%
4387552 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.52 42.0 4.32e-01 91.2% 94.1%
3504305 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 43.0 4.18e-01 92.3% 82.9%
4034409 1075.1.2.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.52 45.0 3.95e-01 100.0% 93.8%
4937575 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 41.0 4.20e-01 90.1% 90.0%
3934523 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.51 42.0 4.21e-01 91.2% 90.5%
3932692 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.51 42.0 4.26e-01 91.2% 98.9%
3939162 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 42.0 3.90e-01 91.2% 76.7%
3934928 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 42.0 4.16e-01 91.2% 90.5%
3932407 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.51 45.0 3.39e-01 100.0% 49.6%
4019223 4983.1.1.0 ↗ alpha superhelices › Indoleamine 2,3-dioxygenase N-terminal subdomain › Indoleamine 2,3-dioxygenase N-terminal subdomain › Indoleamine 2,3-dioxygenase N-terminal subdomain 0.50 43.0 3.69e-01 96.7% 71.3%
3208722 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.50 41.0 3.89e-01 91.2% 73.6%
4957181 603.1.1.242 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF5667 0.50 44.0 3.78e-01 95.6% 98.6%
D4 medium residues 167-215_290-355
PDB
Domain cluster: representative
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.73 50.0 4.54e-01 93.9% 53.6%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.68 39.0 3.54e-01 94.8% 42.2%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.67 48.0 4.35e-01 92.2% 55.6%
7e84A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 49.0 4.85e-01 76.5% 87.0%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 55.0 5.67e-01 94.8% 92.7%
1ciyA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.66 51.0 4.09e-01 98.3% 42.1%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.66 46.0 4.63e-01 92.2% 71.1%
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 50.0 4.56e-01 93.0% 60.5%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 48.0 5.29e-01 77.4% 100.0%
1dlcA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.63 48.0 3.84e-01 94.8% 40.2%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 57.0 5.68e-01 97.4% 95.7%
7utzR02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 51.0 3.87e-01 89.6% 79.5%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 48.0 4.41e-01 95.7% 63.8%
1yf2A02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.61 47.0 4.86e-01 80.0% 99.1%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 48.0 4.58e-01 89.6% 70.3%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 50.0 5.12e-01 91.3% 90.2%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 52.0 5.41e-01 95.7% 96.3%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 52.0 5.32e-01 100.0% 95.4%
5mq1A00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.60 37.0 3.83e-01 91.3% 63.9%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.60 47.0 4.81e-01 90.4% 85.6%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 50.0 4.75e-01 99.1% 77.2%
1gqiA03 3.90.1330.10 Alpha Beta › Alpha-Beta Complex › Alpha-d-glucuronidase, C-terminal Domain › Alpha-glucuronidase, C-terminal domain 0.59 50.0 3.99e-01 93.0% 73.8%
4mycA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.59 51.0 3.63e-01 92.2% 43.0%
5iduC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 46.0 4.14e-01 95.7% 59.7%
3b77B02 1.10.287.210 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 42.0 4.72e-01 78.3% 96.6%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 49.0 5.03e-01 96.5% 92.9%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.58 51.0 4.79e-01 100.0% 82.9%
1nu7D01 1.20.120.750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle domain 1 0.57 43.0 4.10e-01 78.3% 71.9%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 45.0 4.75e-01 93.0% 96.0%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 43.0 4.47e-01 79.1% 89.9%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.56 43.0 4.05e-01 80.0% 70.7%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.56 47.0 4.58e-01 100.0% 81.6%
3lxuX06 1.25.40.710 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 48.0 3.72e-01 93.0% 61.2%
4fwvA02 1.20.120.1680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 45.0 4.27e-01 85.2% 85.1%
4wr4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 40.0 4.19e-01 99.1% 82.9%
3b8mC02 1.10.287.210 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 42.0 4.41e-01 80.0% 92.3%
2o8bB03 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.55 47.0 3.93e-01 93.0% 55.3%
4y9jA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 45.0 4.20e-01 95.7% 70.5%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 44.0 4.56e-01 97.4% 94.4%
3rrkA02 1.20.1460.20 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › 0.54 42.0 3.86e-01 82.6% 63.9%
3khkB01 1.20.1260.30 Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain 0.54 43.0 3.88e-01 85.2% 83.0%
3llwD00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.54 41.0 3.07e-01 92.2% 32.2%
5ux2B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 48.0 3.86e-01 96.5% 64.0%
3m92A01 3.30.300.360 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Protein of unknown function (DUF2498) 0.53 29.0 3.67e-01 90.4% 89.9%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 43.0 4.01e-01 99.1% 71.1%
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.52 32.0 3.50e-01 79.1% 74.7%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4069414 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 55.0 4.71e-01 79.1% 74.1%
4270827 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 54.0 4.58e-01 79.1% 98.9%
4952130 3714.1.1.1 ↗ a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › LonC_helical 0.69 55.0 4.25e-01 82.6% 69.1%
3608835 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 59.0 5.57e-01 98.3% 94.8%
3492369 622.4.1.21 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Frag1 0.64 51.0 5.10e-01 84.3% 93.3%
3881428 3835.1.1.1 ↗ alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › PLC-beta_C 0.64 48.0 4.05e-01 79.1% 48.9%
3631798 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.64 55.0 4.21e-01 93.0% 41.5%
3705513 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 57.0 5.45e-01 98.3% 96.3%
3605561 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 57.0 5.07e-01 99.1% 89.1%
3190737 5001.1.1.115 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Frag1 0.64 51.0 4.10e-01 86.1% 90.7%
3675873 3291.1.1.1 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.63 48.0 4.09e-01 80.0% 52.4%
3522104 601.11.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Perilipin 0.63 57.0 4.73e-01 100.0% 67.5%
3801589 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 54.0 4.61e-01 100.0% 58.9%
3694080 3758.1.1.0 ↗ alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.62 54.0 3.88e-01 96.5% 61.5%
3597988 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.62 52.0 4.65e-01 98.3% 65.6%
3743755 604.12.1.4 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.61 51.0 4.95e-01 90.4% 86.2%
3191834 4207.1.1.1 ↗ alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Med21 0.61 45.0 4.21e-01 77.4% 65.7%
3722363 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.60 54.0 4.79e-01 96.5% 72.5%
3605252 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.60 45.0 3.98e-01 78.3% 84.2%
3715499 109.4.1.623 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1 0.60 55.0 3.17e-01 98.3% 17.0%
3619580 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.60 44.0 4.65e-01 77.4% 93.3%
3395845 109.4.1.514 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps54 0.60 54.0 3.37e-01 98.3% 22.8%
3573612 3615.1.1.1 ↗ alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Fzo_mitofusin 0.59 54.0 3.66e-01 100.0% 53.7%
3516337 604.7.1.0 ↗ alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.59 50.0 5.18e-01 90.4% 99.1%
5081054 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.59 45.0 4.02e-01 80.0% 84.4%
3668148 601.1.1.56 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF7798 0.59 51.0 3.92e-01 92.2% 65.7%
3802401 5050.1.1.2 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.58 51.0 4.15e-01 95.7% 88.4%
4021846 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 52.0 3.99e-01 95.7% 61.6%
4369161 3615.1.1.0 ↗ alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.58 44.0 4.16e-01 86.1% 66.4%
3690657 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.58 48.0 4.48e-01 89.6% 97.1%
4945037 1075.1.2.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.58 52.0 4.78e-01 96.5% 97.2%
4128176 6108.1.1.0 ↗ alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins 0.57 52.0 3.27e-01 100.0% 32.2%
3436384 5050.1.1.2 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.57 51.0 4.02e-01 98.3% 84.9%
5052572 5079.1.1.1 ↗ alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.57 49.0 4.43e-01 93.0% 83.5%
3610597 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 51.0 4.71e-01 100.0% 77.2%
3703032 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 49.0 4.77e-01 92.2% 91.2%
3978183 304.58.1.0 ↗ a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.57 43.0 3.22e-01 79.1% 43.6%
4069075 2004.1.1.73 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.56 52.0 3.50e-01 100.0% 31.1%
3392569 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.56 49.0 4.75e-01 93.0% 88.8%
3601853 604.7.1.0 ↗ alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.56 49.0 4.61e-01 98.3% 97.2%
4941726 5079.1.1.1 ↗ alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.56 47.0 3.78e-01 90.4% 60.0%
3766746 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 38.0 3.18e-01 73.0% 50.3%
3519442 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 47.0 4.31e-01 99.1% 84.5%
3402316 633.1.1.1 ↗ alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain 0.53 40.0 3.86e-01 80.9% 93.3%
3601776 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.52 47.0 3.41e-01 100.0% 39.4%
3343645 3965.1.1.0 ↗ alpha arrays › Origin recognition complex subunit 3 helical insert domain › Origin recognition complex subunit 3 helical insert domain › Origin recognition complex subunit 3 helical insert domain 0.52 49.0 4.11e-01 100.0% 92.4%
3733568 192.8.1.342 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › PHM7_cyt 0.50 42.0 4.08e-01 91.3% 99.2%