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term4_saliva_scaffold_1_prodigal-single.1__X__X__00221
Bact-Virterm4_saliva_scaffold_1_prodigal-single.1__X__X__00221
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 6-122
Domain cluster:
representative
CATH (84)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.81 | 49.0 | 4.64e-01 | 100.0% | 51.1% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.79 | 47.0 | 5.63e-01 | 97.4% | 87.5% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.78 | 55.0 | 5.21e-01 | 100.0% | 62.0% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.78 | 62.0 | 5.56e-01 | 97.4% | 62.4% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.76 | 64.0 | 5.68e-01 | 100.0% | 65.2% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.75 | 59.0 | 5.45e-01 | 95.7% | 66.4% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.75 | 47.0 | 5.44e-01 | 100.0% | 88.1% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 53.0 | 5.27e-01 | 100.0% | 70.8% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 42.0 | 4.48e-01 | 75.2% | 63.1% |
| 3qhbA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 53.0 | 4.60e-01 | 74.4% | 93.9% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.74 | 59.0 | 4.72e-01 | 100.0% | 44.3% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.74 | 62.0 | 5.31e-01 | 100.0% | 58.4% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.74 | 59.0 | 4.77e-01 | 100.0% | 45.6% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.74 | 60.0 | 5.05e-01 | 100.0% | 52.9% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.74 | 49.0 | 5.12e-01 | 94.9% | 73.1% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 62.0 | 5.91e-01 | 100.0% | 77.6% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 61.0 | 5.61e-01 | 100.0% | 69.3% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.73 | 59.0 | 4.93e-01 | 100.0% | 51.5% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 55.0 | 5.29e-01 | 100.0% | 71.5% |
| 2jswA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.71 | 61.0 | 5.12e-01 | 100.0% | 56.6% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.71 | 52.0 | 4.98e-01 | 100.0% | 66.2% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.71 | 55.0 | 5.09e-01 | 100.0% | 64.2% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.71 | 64.0 | 6.50e-01 | 100.0% | 100.0% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 53.0 | 5.11e-01 | 100.0% | 70.8% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 65.0 | 4.80e-01 | 100.0% | 74.6% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 50.0 | 5.01e-01 | 96.6% | 72.5% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 52.0 | 5.08e-01 | 100.0% | 71.9% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 55.0 | 5.53e-01 | 97.4% | 83.8% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.69 | 63.0 | 5.84e-01 | 100.0% | 80.4% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 64.0 | 4.80e-01 | 99.1% | 84.0% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.69 | 53.0 | 4.85e-01 | 100.0% | 62.3% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.68 | 49.0 | 4.97e-01 | 99.1% | 76.1% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 64.0 | 4.78e-01 | 100.0% | 83.1% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 59.0 | 5.71e-01 | 100.0% | 83.1% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 57.0 | 5.70e-01 | 100.0% | 87.4% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 52.0 | 5.16e-01 | 100.0% | 77.0% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.68 | 51.0 | 5.19e-01 | 100.0% | 80.2% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.68 | 63.0 | 4.85e-01 | 100.0% | 81.2% |
| 1hciA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 45.0 | 4.46e-01 | 76.9% | 63.5% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 54.0 | 4.69e-01 | 100.0% | 56.1% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 61.0 | 4.78e-01 | 99.1% | 73.1% |
| 2oexA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.67 | 62.0 | 5.76e-01 | 100.0% | 86.7% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 45.0 | 5.29e-01 | 74.4% | 97.6% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 45.0 | 4.47e-01 | 76.9% | 66.1% |
| 3u0cA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.67 | 50.0 | 4.50e-01 | 76.9% | 60.3% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 50.0 | 4.18e-01 | 98.3% | 45.9% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 49.0 | 4.92e-01 | 99.1% | 77.7% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 59.0 | 4.86e-01 | 100.0% | 91.4% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 60.0 | 4.54e-01 | 100.0% | 82.3% |
| 3ajwA00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 48.0 | 4.59e-01 | 76.9% | 68.7% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 48.0 | 3.83e-01 | 76.9% | 43.7% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.64 | 47.0 | 4.73e-01 | 94.0% | 74.4% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.64 | 54.0 | 4.79e-01 | 98.3% | 63.1% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 56.0 | 4.77e-01 | 93.2% | 84.0% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.64 | 43.0 | 4.98e-01 | 77.8% | 97.6% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 47.0 | 3.66e-01 | 76.9% | 38.0% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 56.0 | 4.61e-01 | 94.0% | 79.0% |
| 3g9gA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 58.0 | 4.47e-01 | 100.0% | 75.6% |
| 1qu7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.63 | 45.0 | 3.57e-01 | 76.9% | 38.3% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.62 | 57.0 | 5.28e-01 | 100.0% | 81.5% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 54.0 | 4.16e-01 | 95.7% | 80.2% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 56.0 | 4.43e-01 | 99.1% | 84.0% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 55.0 | 4.33e-01 | 99.1% | 82.4% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 55.0 | 4.14e-01 | 99.1% | 79.3% |
| 1aluA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.60 | 43.0 | 3.88e-01 | 73.5% | 100.0% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.60 | 47.0 | 4.74e-01 | 82.9% | 95.8% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.60 | 42.0 | 3.83e-01 | 95.7% | 51.8% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 54.0 | 4.37e-01 | 99.1% | 84.9% |
| 4yonA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.59 | 41.0 | 3.39e-01 | 70.9% | 84.7% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.59 | 48.0 | 5.05e-01 | 86.3% | 98.1% |
| 1w33A00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.59 | 54.0 | 4.63e-01 | 100.0% | 80.7% |
| 1f6fA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 43.0 | 3.72e-01 | 77.8% | 88.5% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.58 | 47.0 | 4.36e-01 | 100.0% | 66.7% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.58 | 49.0 | 4.22e-01 | 95.7% | 58.1% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.58 | 42.0 | 4.58e-01 | 76.9% | 93.8% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 50.0 | 3.86e-01 | 99.1% | 77.1% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.57 | 42.0 | 3.89e-01 | 100.0% | 61.0% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 50.0 | 3.89e-01 | 100.0% | 45.6% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.56 | 47.0 | 4.43e-01 | 100.0% | 73.4% |
| 1dbhA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.55 | 46.0 | 3.86e-01 | 93.2% | 98.1% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.54 | 48.0 | 4.35e-01 | 97.4% | 85.4% |
| 4jvsA01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 49.0 | 4.83e-01 | 100.0% | 98.4% |
| 3dytA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 45.0 | 3.89e-01 | 95.7% | 92.6% |
| 3nrhA00 | 1.20.120.1550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Protein of unknown function DUF5063 | 0.51 | 45.0 | 4.09e-01 | 100.0% | 93.7% |
ECOD (80)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3672657 | 3755.4.1.23 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF7032 | 0.82 | 57.0 | 5.21e-01 | 100.0% | 56.0% |
| 3862625 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.78 | 59.0 | 5.52e-01 | 100.0% | 65.7% |
| 3832044 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.78 | 65.0 | 6.56e-01 | 100.0% | 88.7% |
| 3975942 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.77 | 43.0 | 4.16e-01 | 72.6% | 49.2% |
| 3554799 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.76 | 54.0 | 5.31e-01 | 99.1% | 68.0% |
| 3529790 | 601.1.1.57 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_VBS2 | 0.76 | 59.0 | 5.69e-01 | 100.0% | 73.1% |
| 2596506 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.75 | 63.0 | 5.69e-01 | 100.0% | 66.9% |
| 4220561 | 601.1.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C | 0.75 | 55.0 | 5.36e-01 | 98.3% | 69.0% |
| 3798573 | 601.1.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C | 0.75 | 64.0 | 5.73e-01 | 100.0% | 67.1% |
| 4943286 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.75 | 52.0 | 4.77e-01 | 70.9% | 60.1% |
| 5045846 | 633.6.1.55 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › DUF1512 | 0.74 | 68.0 | 6.09e-01 | 100.0% | 83.7% |
| 2396196 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.74 | 56.0 | 5.40e-01 | 100.0% | 70.5% |
| 5066877 | 3633.1.1.4 ↗ | alpha duplicates or obligate multimers › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor › DUF1512 | 0.74 | 67.0 | 5.75e-01 | 100.0% | 83.2% |
| 3814372 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.73 | 60.0 | 6.27e-01 | 94.9% | 96.2% |
| 4013484 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.72 | 49.0 | 4.03e-01 | 70.1% | 81.0% |
| 5023736 | 192.29.1.303 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF1512 | 0.72 | 66.0 | 6.01e-01 | 98.3% | 100.0% |
| 3411249 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.72 | 55.0 | 5.32e-01 | 97.4% | 71.5% |
| 5036028 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.71 | 54.0 | 5.05e-01 | 100.0% | 64.8% |
| 3450208 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.71 | 61.0 | 5.05e-01 | 100.0% | 54.9% |
| 4018180 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.71 | 49.0 | 3.72e-01 | 70.9% | 65.9% |
| 1761248 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.70 | 60.0 | 5.00e-01 | 100.0% | 54.3% |
| 3440229 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 64.0 | 5.37e-01 | 100.0% | 74.4% |
| 4959549 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.70 | 53.0 | 4.54e-01 | 97.4% | 50.3% |
| 4133341 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.70 | 48.0 | 4.79e-01 | 100.0% | 68.3% |
| 3625011 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 57.0 | 5.20e-01 | 100.0% | 66.5% |
| 3557360 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.70 | 65.0 | 4.81e-01 | 100.0% | 71.8% |
| 3880326 | 4177.2.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain | 0.69 | 65.0 | 4.73e-01 | 100.0% | 69.3% |
| 3277855 | 3562.1.1.3 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › DUF6328 | 0.69 | 57.0 | 5.31e-01 | 100.0% | 71.0% |
| 3378097 | 604.1.1.110 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › WIT1_2_N | 0.69 | 44.0 | 4.40e-01 | 75.2% | 62.5% |
| 3426522 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.69 | 59.0 | 5.66e-01 | 98.3% | 80.0% |
| 1824764 | 1189.1.1.4 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › HpHbR | 0.68 | 63.0 | 4.88e-01 | 100.0% | 79.9% |
| 3415295 | 4177.1.1.38 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Tektin | 0.68 | 63.0 | 5.81e-01 | 100.0% | 88.7% |
| 5054165 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.68 | 47.0 | 3.78e-01 | 100.0% | 37.3% |
| 4084678 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.68 | 59.0 | 6.11e-01 | 95.7% | 100.0% |
| 3698277 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.68 | 64.0 | 5.68e-01 | 100.0% | 81.9% |
| 3187418 | 601.1.2.149 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF30922 | 0.68 | 45.0 | 4.60e-01 | 96.6% | 68.7% |
| 3403179 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.68 | 45.0 | 4.76e-01 | 75.2% | 75.2% |
| 3272925 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.67 | 55.0 | 5.37e-01 | 100.0% | 80.8% |
| 3729299 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 55.0 | 5.03e-01 | 100.0% | 66.5% |
| 4118417 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.66 | 47.0 | 4.55e-01 | 100.0% | 65.4% |
| 3971056 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.66 | 48.0 | 4.84e-01 | 87.2% | 73.3% |
| 3720276 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.66 | 61.0 | 4.41e-01 | 99.1% | 70.6% |
| 3488340 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.66 | 51.0 | 5.20e-01 | 100.0% | 83.5% |
| 3378238 | 192.29.1.115 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF599 | 0.66 | 61.0 | 4.89e-01 | 100.0% | 59.1% |
| 3517735 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.66 | 60.0 | 5.00e-01 | 100.0% | 87.5% |
| 3223631 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.65 | 59.0 | 5.23e-01 | 100.0% | 70.0% |
| 4253649 | 601.4.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH | 0.65 | 50.0 | 4.71e-01 | 100.0% | 67.9% |
| 3937801 | 4177.1.1.38 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Tektin | 0.65 | 60.0 | 4.97e-01 | 100.0% | 76.5% |
| 3601550 | 207.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats | 0.65 | 60.0 | 3.44e-01 | 100.0% | 18.8% |
| 3440913 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.64 | 58.0 | 5.60e-01 | 100.0% | 86.7% |
| 3755568 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.64 | 59.0 | 4.92e-01 | 100.0% | 79.0% |
| 3290817 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.64 | 49.0 | 4.63e-01 | 99.1% | 67.1% |
| 4963908 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.64 | 53.0 | 5.03e-01 | 100.0% | 74.1% |
| 4929564 | 5057.1.1.1 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb | 0.64 | 49.0 | 4.81e-01 | 98.3% | 74.2% |
| 4986424 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.64 | 44.0 | 4.15e-01 | 70.1% | 87.9% |
| 3730903 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.64 | 47.0 | 4.36e-01 | 99.1% | 60.7% |
| 4950911 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.63 | 47.0 | 4.35e-01 | 76.9% | 80.7% |
| 4932401 | 3930.1.1.3 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical | 0.63 | 53.0 | 5.14e-01 | 93.2% | 80.8% |
| 4663047 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 46.0 | 3.69e-01 | 76.9% | 40.9% |
| 3685679 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 57.0 | 5.18e-01 | 100.0% | 81.9% |
| 3283506 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 45.0 | 4.71e-01 | 100.0% | 83.8% |
| 3417771 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.62 | 46.0 | 3.62e-01 | 76.9% | 41.8% |
| 3783873 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.62 | 52.0 | 4.95e-01 | 89.7% | 89.6% |
| 2722116 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.61 | 56.0 | 4.68e-01 | 100.0% | 64.3% |
| 3170937 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.61 | 54.0 | 4.07e-01 | 95.7% | 83.3% |
| 3473142 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 45.0 | 4.23e-01 | 76.1% | 64.3% |
| 4941675 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.61 | 44.0 | 2.88e-01 | 76.9% | 18.1% |
| 3701568 | 601.1.1.99 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Got1 | 0.60 | 47.0 | 4.54e-01 | 100.0% | 71.9% |
| 4216904 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.59 | 53.0 | 4.35e-01 | 99.1% | 54.3% |
| 3202451 | 3567.1.1.51 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Fung_rhodopsin | 0.59 | 53.0 | 4.56e-01 | 100.0% | 92.1% |
| 3275929 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.59 | 52.0 | 5.08e-01 | 100.0% | 86.9% |
| 3970945 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.58 | 46.0 | 4.65e-01 | 99.1% | 85.2% |
| 4507149 | 4177.1.1.9 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Snx8_BAR_dom | 0.58 | 53.0 | 4.27e-01 | 98.3% | 92.7% |
| 1518904 | 601.40.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › N-terminal domain in uncharacterized DUF3829-like protein › N-terminal domain in uncharacterized DUF3829-like protein › DUF6845 | 0.58 | 47.0 | 4.36e-01 | 100.0% | 66.7% |
| 3713791 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 38.0 | 3.96e-01 | 72.6% | 70.9% |
| 3768053 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.56 | 52.0 | 4.69e-01 | 100.0% | 78.1% |
| 3284257 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.56 | 50.0 | 4.66e-01 | 100.0% | 79.3% |
| 3462375 | 3755.4.1.46 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › NET2A | 0.54 | 49.0 | 4.05e-01 | 100.0% | 57.6% |
| 3725261 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.53 | 47.0 | 3.52e-01 | 99.1% | 79.3% |
| 3881428 | 3835.1.1.1 ↗ | alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › PLC-beta_C | 0.53 | 38.0 | 3.27e-01 | 76.9% | 46.8% |