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term4_saliva_scaffold_5_prodigal-single.1__X__X__00177
Bact-Virterm4_saliva_scaffold_5_prodigal-single.1__X__X__00177
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-188
Domain cluster:
rep: NC_021330__YP_008059651.1__M202-gp129__00089__D21-171
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07728.21 best | AAA_5 | 35.1 | 1.70e-08 | 80.2% | 92.8% |
| PF00004.36 | AAA | 22.2 | 2.30e-04 | 80.2% | 85.5% |
D2
high
residues 199-318
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tzvA00 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.67 | 44.0 | 4.24e-01 | 95.0% | 56.7% |
| 4unfA02 | 1.10.340.30 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2 | 0.65 | 41.0 | 4.16e-01 | 96.7% | 63.2% |
| 3vw4A01 | 1.10.340.50 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › | 0.64 | 37.0 | 4.19e-01 | 80.0% | 75.0% |
| 3r2cA00 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.62 | 41.0 | 3.92e-01 | 95.0% | 58.0% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.60 | 39.0 | 4.57e-01 | 93.3% | 97.5% |
| 6tmfT00 | 1.10.60.20 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 | 0.55 | 30.0 | 3.77e-01 | 80.0% | 96.9% |
| 2anvA00 | 1.10.530.40 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.53 | 36.0 | 3.43e-01 | 97.5% | 56.8% |
| 1wlmA01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.53 | 34.0 | 3.66e-01 | 86.7% | 74.8% |
| 4qnsA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.53 | 42.0 | 4.47e-01 | 92.5% | 97.2% |
| 3u5nA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 44.0 | 4.49e-01 | 95.0% | 96.7% |
| 2yqdA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.50 | 41.0 | 4.19e-01 | 94.2% | 90.8% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3589948 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.66 | 42.0 | 4.05e-01 | 94.2% | 55.0% |
| 3838730 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.65 | 47.0 | 4.09e-01 | 91.7% | 50.9% |
| 3296661 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.62 | 41.0 | 3.70e-01 | 95.0% | 47.6% |
| 3998882 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.59 | 35.0 | 4.00e-01 | 90.8% | 82.4% |
| 3670373 | 5054.1.1.70 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Yip1 | 0.58 | 49.0 | 5.09e-01 | 92.5% | 97.3% |
| 4170883 | 103.7.1.2 ↗ | alpha arrays › RuvA-C › Hypothetical protein MTH1615 › Hypothetical protein MTH1615 › DUF494 | 0.58 | 39.0 | 4.19e-01 | 94.2% | 82.0% |
| 3643402 | 592.1.1.0 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain | 0.57 | 41.0 | 3.91e-01 | 93.3% | 64.3% |
| 5022220 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.56 | 37.0 | 3.62e-01 | 94.2% | 58.5% |
| 5003414 | 7014.1.1.2 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE | 0.54 | 42.0 | 3.36e-01 | 82.5% | 52.2% |
| 3493369 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.53 | 45.0 | 4.48e-01 | 96.7% | 91.2% |
| 3166830 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.50 | 43.0 | 4.20e-01 | 93.3% | 86.9% |
| 4183120 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.50 | 43.0 | 4.07e-01 | 96.7% | 77.9% |
| 3226183 | 633.23.1.14 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_3 | 0.50 | 41.0 | 3.75e-01 | 91.7% | 94.6% |
D3
high
residues 323-475
Domain cluster:
representative
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.76 | 32.0 | 4.60e-01 | 70.6% | 82.7% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 37.0 | 4.07e-01 | 77.1% | 56.9% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 38.0 | 4.36e-01 | 77.1% | 65.8% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.72 | 40.0 | 4.66e-01 | 71.2% | 75.2% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.69 | 43.0 | 5.04e-01 | 70.6% | 88.2% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.68 | 31.0 | 4.30e-01 | 71.2% | 86.7% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.67 | 36.0 | 3.85e-01 | 77.8% | 58.4% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.64 | 37.0 | 4.37e-01 | 80.4% | 83.3% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.63 | 50.0 | 4.59e-01 | 83.7% | 90.5% |
| 2i2xB01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.62 | 38.0 | 4.50e-01 | 93.5% | 91.0% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 40.0 | 4.00e-01 | 77.8% | 65.6% |
| 5cy5B00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.58 | 40.0 | 4.08e-01 | 81.0% | 71.8% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.57 | 39.0 | 4.49e-01 | 81.0% | 93.0% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 39.0 | 4.10e-01 | 81.7% | 77.7% |
| 2w2dD01 | 1.20.1120.10 | Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" | 0.56 | 40.0 | 3.01e-01 | 74.5% | 56.3% |
| 3ha4B00 | 1.20.58.690 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 36.0 | 4.00e-01 | 100.0% | 81.7% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 37.0 | 3.75e-01 | 73.9% | 68.7% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.54 | 40.0 | 3.76e-01 | 77.1% | 64.9% |
| 1txdA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.54 | 41.0 | 3.60e-01 | 79.1% | 61.9% |
| 3ubcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 34.0 | 3.59e-01 | 71.2% | 71.0% |
| 3x0uB01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.53 | 49.0 | 4.19e-01 | 100.0% | 81.5% |
| 1wvtA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.53 | 40.0 | 4.07e-01 | 77.8% | 82.4% |
| 1x9fC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 35.0 | 3.59e-01 | 71.9% | 67.8% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 35.0 | 3.92e-01 | 78.4% | 84.4% |
| 2fo7A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 32.0 | 3.41e-01 | 98.0% | 66.9% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 39.0 | 3.94e-01 | 77.8% | 83.5% |
| 2rasA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 40.0 | 3.76e-01 | 82.4% | 89.0% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.52 | 45.0 | 4.12e-01 | 100.0% | 70.9% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 45.0 | 3.89e-01 | 96.1% | 78.8% |
| 4o8sA02 | 1.20.58.1790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › JHP933, helical tail domain | 0.50 | 32.0 | 3.72e-01 | 98.7% | 90.7% |
| 2fzfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 38.0 | 3.90e-01 | 78.4% | 85.3% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4982818 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.64 | 34.0 | 3.89e-01 | 78.4% | 67.5% |
| 3822258 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.63 | 34.0 | 3.60e-01 | 76.5% | 57.9% |
| 3459287 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 38.0 | 3.72e-01 | 77.1% | 55.8% |
| 4027056 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 39.0 | 4.10e-01 | 70.6% | 70.7% |
| 4312016 | 601.4.1.49 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TMEM171 | 0.60 | 35.0 | 3.64e-01 | 71.9% | 59.3% |
| 3690080 | 603.5.1.0 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like | 0.60 | 43.0 | 4.83e-01 | 75.8% | 95.0% |
| 3287092 | 604.39.1.9 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › Vut_1 | 0.58 | 42.0 | 3.80e-01 | 75.2% | 58.6% |
| 3290528 | 109.3.1.379 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF4153 | 0.58 | 43.0 | 3.78e-01 | 77.1% | 54.7% |
| 3493827 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.57 | 43.0 | 4.67e-01 | 83.7% | 91.5% |
| 3731168 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 37.0 | 4.34e-01 | 98.0% | 95.2% |
| 137835 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.56 | 50.0 | 4.52e-01 | 96.1% | 87.1% |
| 3797233 | 603.5.1.0 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like | 0.55 | 50.0 | 4.78e-01 | 100.0% | 95.0% |
| 3625427 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 37.0 | 4.19e-01 | 83.7% | 91.3% |
| 3401839 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 39.0 | 4.12e-01 | 81.0% | 83.7% |
| 3502133 | 109.4.1.2119 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, HAT_Syf1_M, HAT_Syf1_CNRKL1_C, HAT_Syf1_CNRKL1_N | 0.54 | 45.0 | 2.93e-01 | 96.1% | 18.0% |
| 5064713 | 1075.1.1.19 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_4 | 0.54 | 39.0 | 3.30e-01 | 74.5% | 85.4% |
| 5077440 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.54 | 43.0 | 4.53e-01 | 100.0% | 93.6% |
| 4024825 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 49.0 | 4.65e-01 | 100.0% | 85.5% |
| 3655342 | 5082.1.1.0 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like | 0.53 | 40.0 | 3.67e-01 | 77.1% | 77.9% |
| 3960608 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.53 | 36.0 | 3.83e-01 | 76.5% | 79.2% |
| 4934327 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.53 | 48.0 | 4.27e-01 | 98.0% | 89.3% |
| 5028719 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.53 | 37.0 | 3.21e-01 | 72.5% | 97.6% |
| 4021431 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 40.0 | 4.16e-01 | 81.7% | 85.0% |
| None | — | 0.52 | 46.0 | 3.75e-01 | 99.3% | 93.5% | |
| 3199411 | 109.4.1.514 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps54 | 0.52 | 44.0 | 3.81e-01 | 93.5% | 77.3% |
| 4974859 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.52 | 38.0 | 3.36e-01 | 76.5% | 96.6% |
| 3836802 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.52 | 40.0 | 3.87e-01 | 81.7% | 71.8% |
| 4972025 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.51 | 38.0 | 3.52e-01 | 77.1% | 70.2% |
| 3932492 | 5001.1.1.63 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab | 0.51 | 39.0 | 3.65e-01 | 81.0% | 63.8% |
| 3202751 | 109.4.1.1319 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans, PF31024 | 0.51 | 46.0 | 3.24e-01 | 100.0% | 34.4% |
| 5047572 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.51 | 41.0 | 3.58e-01 | 85.6% | 76.4% |
| 4955441 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.50 | 37.0 | 3.26e-01 | 96.7% | 50.9% |