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thiol_protease

Euk-Vir

Phaeocystis_globosa_virus

thiol_protease__YP_008052642__Phaeocystis_globosa_virus__251749

Identity

Accession:
YP_008052642 ↗
Protein ID:
thiol_protease
Kingdom:
euk

Quality

72.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 112-293
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02902.26 best Peptidase_C48 38.5 1.60e-09 73.1% 51.6%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1th0B00 3.40.395.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A 0.75 70.0 6.47e-01 100.0% 79.4%
1xt9A00 3.40.395.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A 0.75 71.0 6.77e-01 100.0% 87.5%
4ekfA00 3.40.395.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenoviral Proteinase; Chain › Adenoviral Proteinase; Chain A 0.72 64.0 6.35e-01 96.7% 88.5%
1euvA02 3.30.310.130 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Ubiquitin-related 0.68 40.0 5.20e-01 77.5% 100.0%
7c2fB01 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.63 31.0 4.32e-01 75.3% 96.5%
1tigA00 3.30.110.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Translation initiation factor 3 (IF-3), C-terminal domain 0.62 30.0 4.10e-01 71.4% 93.2%
7c2gG01 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.60 30.0 4.28e-01 83.0% 100.0%
3lyhA00 3.40.50.1400 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 35.0 4.10e-01 94.0% 84.2%
3r3pB00 3.40.960.10 Alpha Beta › 3-Layer(aba) Sandwich › Endonuclease; Chain A › VSR Endonuclease 0.57 31.0 4.15e-01 83.0% 99.0%
5ysnB02 3.40.50.11240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Ethanolamine ammonia-lyase light chain (EutC) 0.57 38.0 3.83e-01 87.9% 65.4%
1nmnA00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.54 33.0 3.89e-01 83.5% 89.2%
2b99C00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.54 40.0 4.30e-01 91.2% 90.8%
6ecpB01 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.54 32.0 3.49e-01 83.0% 70.3%
2ayaA00 3.30.300.150 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › DNA polymerase III, tau subunit, domain V 0.53 32.0 3.71e-01 95.6% 82.8%
2yv4A00 3.40.50.11030 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Threonylcarbamoyl-AMP synthase, C-terminal domain 0.52 28.0 3.60e-01 96.2% 91.2%
3pbkA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.52 31.0 3.79e-01 76.9% 96.3%
1di0A00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.52 35.0 3.89e-01 83.5% 85.1%
4lizA00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.51 35.0 3.95e-01 70.9% 89.9%
1d0nA03 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.51 31.0 3.66e-01 81.9% 87.6%
1lw7A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.51 34.0 3.59e-01 100.0% 72.2%
1jjfA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 40.0 3.62e-01 84.1% 73.7%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None 0.78 70.0 6.57e-01 100.0% 79.1%
7400 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.78 70.0 6.49e-01 100.0% 77.4%
2410593 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.78 73.0 6.30e-01 98.9% 85.0%
3416006 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.76 71.0 6.46e-01 100.0% 77.0%
3783242 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.76 69.0 6.32e-01 100.0% 75.7%
3696004 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.75 71.0 6.48e-01 100.0% 79.1%
3498187 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.75 71.0 6.46e-01 100.0% 77.4%
3466516 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 70.0 6.34e-01 100.0% 86.3%
3737708 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 71.0 6.25e-01 100.0% 79.7%
3209165 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 71.0 6.29e-01 100.0% 74.7%
3875060 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 70.0 6.50e-01 100.0% 83.6%
3776113 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 70.0 6.13e-01 100.0% 87.7%
3404797 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 69.0 6.56e-01 100.0% 86.1%
3517168 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 70.0 6.43e-01 100.0% 84.9%
3626575 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.74 69.0 6.54e-01 100.0% 87.3%
3256272 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 70.0 6.34e-01 100.0% 79.9%
3369707 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 70.0 5.89e-01 100.0% 64.9%
3659695 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 69.0 6.43e-01 100.0% 87.9%
4026880 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 70.0 6.25e-01 100.0% 80.0%
3189169 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 69.0 6.38e-01 100.0% 85.3%
3228402 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 67.0 6.38e-01 100.0% 84.8%
3410176 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 69.0 6.46e-01 100.0% 87.0%
3974984 219.1.1.67 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › ElaD-SseL-like_C,ElaD_SseL-like_N 0.73 69.0 5.56e-01 100.0% 67.4%
3994259 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 68.0 6.22e-01 100.0% 91.1%
3788927 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.73 68.0 6.07e-01 100.0% 94.0%
3258711 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.72 68.0 6.11e-01 100.0% 88.1%
153044 219.1.1.5 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C5 0.72 64.0 6.35e-01 96.7% 88.5%
3794680 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.71 67.0 5.94e-01 100.0% 79.1%
3737961 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.71 67.0 6.31e-01 100.0% 87.9%
3323220 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.71 67.0 5.71e-01 100.0% 84.3%
3738382 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.71 66.0 6.01e-01 100.0% 78.3%
3635663 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.71 66.0 5.81e-01 100.0% 90.4%
4236698 219.1.1.20 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Acetyltransf_14 0.70 66.0 5.70e-01 100.0% 92.2%
3677902 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.70 65.0 4.49e-01 100.0% 34.7%
3826010 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.69 65.0 5.59e-01 100.0% 80.0%
1870510 219.1.1.20 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Acetyltransf_14 0.67 63.0 5.16e-01 100.0% 87.0%
3678661 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.66 61.0 4.30e-01 100.0% 45.5%
3248679 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.65 55.0 5.81e-01 91.8% 99.4%
2323988 219.1.1.20 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Acetyltransf_14 0.65 60.0 4.89e-01 100.0% 82.5%
5071835 224.1.1.0 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.62 32.0 4.44e-01 82.4% 98.9%
4997461 224.1.1.2 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.61 30.0 4.31e-01 76.4% 97.8%
2643927 224.1.1.2 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.61 31.0 4.34e-01 72.0% 100.0%
5045327 224.1.1.0 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.61 32.0 4.38e-01 72.5% 100.0%
4998632 224.1.1.2 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.61 32.0 4.13e-01 72.5% 90.0%
5000415 224.1.1.0 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.60 31.0 4.04e-01 72.0% 86.7%
3526484 224.1.1.2 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.58 32.0 3.83e-01 84.6% 76.8%
4997307 224.1.1.2 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.57 31.0 4.06e-01 85.2% 95.0%
3654558 219.1.1.16 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C48 0.57 50.0 5.14e-01 95.1% 100.0%
4976954 224.1.1.2 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin 0.56 29.0 3.88e-01 72.0% 100.0%
5072973 224.1.1.0 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.56 33.0 4.20e-01 86.3% 99.0%
4202670 2005.1.1.11 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.55 32.0 2.98e-01 76.9% 44.4%
5053500 224.1.1.0 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.54 31.0 4.01e-01 83.0% 100.0%
4929304 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.51 31.0 3.55e-01 87.9% 82.3%
3213642 7572.1.1.1 a/b three-layered sandwiches › Phosphofructokinase C-terminal domain › Phosphofructokinase C-terminal domain › Phosphofructokinase C-terminal domain › PFK 0.50 34.0 4.01e-01 97.3% 100.0%
D2 medium residues 18-108
PDB