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thymidine_kinase
Euk-VirMeleagrid_alphaherpesvirus_1
thymidine_kinase__NP_073316__Meleagrid_alphaherpesvirus_1__37108
Identity
- Accession:
- NP_073316 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
89.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Mardivirus›
Meleagrid_alphaherpesvirus_1
TaxID: 37108
Cluster
View cluster (35 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 11-43_156-343
Domain cluster:
rep: thymidina_kinase__YP_009664657__Bubaline_alphaherpesvirus_1__202910__D121-329
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 127.8 | 6.70e-37 | 65.6% | 48.6% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1p72A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.87 | 85.0 | 7.25e-01 | 100.0% | 97.8% |
| 1osnC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.86 | 83.0 | 7.17e-01 | 98.6% | 98.7% |
| 1e2jA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.80 | 77.0 | 6.77e-01 | 100.0% | 98.4% |
| 2qorA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 39.0 | 5.07e-01 | 89.6% | 98.5% |
| 6wctD01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 39.0 | 4.70e-01 | 90.5% | 85.7% |
| 4cvnA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 40.0 | 4.42e-01 | 89.1% | 87.2% |
| 6ln3A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 45.0 | 4.69e-01 | 88.7% | 97.5% |
| 1khtB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 43.0 | 4.59e-01 | 87.8% | 99.0% |
| 1xg8A00 | 3.40.30.30 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Hypothetical protein sa0798. | 0.50 | 21.0 | 2.93e-01 | 88.7% | 76.9% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 9545 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.87 | 85.0 | 7.18e-01 | 100.0% | 97.9% |
| 9546 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.86 | 83.0 | 7.07e-01 | 98.6% | 98.5% |
| 1322887 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.80 | 78.0 | 6.81e-01 | 100.0% | 98.0% |
| 5054245 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.59 | 40.0 | 4.60e-01 | 88.7% | 90.5% |
| None | — | 0.57 | 40.0 | 4.46e-01 | 89.1% | 89.1% | |
| 4970123 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.57 | 41.0 | 4.54e-01 | 89.1% | 89.4% |
| 5022990 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.56 | 41.0 | 4.54e-01 | 88.7% | 89.7% |
| 4934321 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.55 | 40.0 | 4.33e-01 | 88.7% | 86.3% |
| 5031231 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.54 | 39.0 | 4.29e-01 | 87.3% | 87.6% |
| 5024224 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.52 | 42.0 | 4.52e-01 | 90.0% | 96.3% |
| 4938237 | 2004.1.1.191 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_17 | 0.51 | 41.0 | 4.55e-01 | 86.9% | 100.0% |
| 3499873 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.51 | 43.0 | 4.51e-01 | 91.0% | 95.5% |
D2
medium
residues 44-155
Domain cluster:
rep: ORF38_gene_product__YP_006273018__Equid_alphaherpesvirus_8__39637__D59-120_334-352
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 116.3 | 2.20e-33 | 100.0% | 41.1% |