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thymidine_kinase
Euk-VirEquid_alphaherpesvirus_9
thymidine_kinase__YP_002333520__Equid_alphaherpesvirus_9__55744
Identity
- Accession:
- YP_002333520 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
88.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
Equid_alphaherpesvirus_9
TaxID: 55744
Cluster
View cluster (35 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 26-350
Domain cluster:
rep: thymidine_kinase__YP_009052001__Elephant_endotheliotropic_herpesvirus_5__768738__D59-313
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 305.3 | 5.60e-91 | 85.2% | 99.6% |
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1p72A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.97 | 93.0 | 9.39e-01 | 100.0% | 97.5% |
| 1osnC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.96 | 90.0 | 9.23e-01 | 99.4% | 98.7% |
| 1e2jA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.96 | 87.0 | 9.03e-01 | 100.0% | 98.0% |
| 1zm7B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.84 | 49.0 | 6.40e-01 | 87.7% | 95.5% |
| 1e9fA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.81 | 49.0 | 6.18e-01 | 94.2% | 95.0% |
| 1kagA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.78 | 39.0 | 5.59e-01 | 92.0% | 98.7% |
| 4mqbB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.76 | 48.0 | 5.97e-01 | 93.5% | 99.5% |
| 3kb2A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.75 | 40.0 | 5.54e-01 | 93.2% | 98.2% |
| 1rkbA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.75 | 40.0 | 5.48e-01 | 94.2% | 97.1% |
| 4loaA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.75 | 37.0 | 5.39e-01 | 92.3% | 98.7% |
| 4cvnA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.74 | 37.0 | 5.03e-01 | 92.9% | 87.2% |
| 3a4lB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.74 | 40.0 | 5.41e-01 | 93.8% | 95.5% |
| 2plrA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.72 | 46.0 | 5.69e-01 | 93.8% | 98.6% |
| 1m8pA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.68 | 39.0 | 5.02e-01 | 93.8% | 95.7% |
| 1bifA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 41.0 | 5.06e-01 | 93.8% | 94.7% |
| 1uejB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 39.0 | 4.85e-01 | 94.2% | 98.6% |
| 3nivC02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 25.0 | 3.98e-01 | 80.9% | 97.6% |
| 2h92A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 38.0 | 4.64e-01 | 92.6% | 99.5% |
| 3f5fA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 36.0 | 3.86e-01 | 92.6% | 69.2% |
| 3oziB00 | 3.40.50.10140 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain | 0.57 | 31.0 | 4.11e-01 | 96.0% | 98.2% |
| 3zidB00 | 3.40.50.1440 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain | 0.57 | 34.0 | 3.43e-01 | 93.5% | 55.6% |
| 2hf9B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 34.0 | 4.14e-01 | 93.8% | 89.5% |
| 2zm5B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 38.0 | 4.50e-01 | 91.7% | 99.6% |
| 4hi0E00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 33.0 | 4.20e-01 | 93.2% | 99.5% |
| 1sbzD00 | 3.40.50.1950 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like | 0.53 | 30.0 | 3.85e-01 | 92.3% | 94.6% |
| 2hc9A01 | 3.40.50.10590 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Zn-dependent exopeptidases | 0.53 | 24.0 | 3.39e-01 | 87.1% | 87.0% |
| 7bovA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.52 | 32.0 | 4.06e-01 | 93.8% | 100.0% |
| 4rgyA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 33.0 | 3.80e-01 | 93.5% | 87.8% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 9545 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.97 | 96.0 | 9.52e-01 | 100.0% | 97.6% |
| 1322887 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.96 | 87.0 | 9.00e-01 | 100.0% | 97.7% |
| 9546 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.94 | 91.0 | 9.12e-01 | 99.4% | 98.5% |
| 3753842 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.85 | 55.0 | 6.61e-01 | 93.2% | 93.3% |
| 5072252 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.84 | 51.0 | 6.48e-01 | 92.0% | 95.6% |
| 5043901 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.82 | 50.0 | 6.39e-01 | 93.2% | 98.5% |
| 4032626 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.82 | 51.0 | 6.42e-01 | 93.5% | 97.1% |
| 5064255 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.81 | 46.0 | 6.15e-01 | 93.2% | 99.4% |
| 4573455 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.79 | 47.0 | 6.12e-01 | 92.3% | 99.5% |
| 4435067 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.77 | 56.0 | 6.39e-01 | 93.5% | 94.1% |
| 5035981 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.77 | 40.0 | 5.26e-01 | 92.9% | 87.0% |
| 9562 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.76 | 40.0 | 5.58e-01 | 92.0% | 100.0% |
| 5054054 | 2004.1.1.191 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_17 | 0.74 | 42.0 | 5.63e-01 | 92.3% | 100.0% |
| 4004342 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 50.0 | 5.87e-01 | 93.8% | 97.4% |
| 3784993 | 2004.1.1.60 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SKI | 0.72 | 41.0 | 5.36e-01 | 93.2% | 95.8% |
| 3337189 | 2004.1.1.208 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_33 | 0.68 | 33.0 | 4.73e-01 | 92.9% | 96.7% |
| 4477375 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.68 | 38.0 | 4.99e-01 | 93.5% | 94.2% |
| 3493918 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.68 | 56.0 | 5.29e-01 | 97.5% | 73.2% |
| 3786098 | 2004.1.1.65 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › 6PF2K | 0.67 | 43.0 | 4.97e-01 | 93.5% | 86.3% |
| 4256195 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.64 | 36.0 | 4.79e-01 | 93.5% | 98.3% |
| 4993881 | 2005.1.1.13 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTP_transf_like | 0.62 | 22.0 | 3.93e-01 | 99.1% | 99.0% |
| 4417566 | 2004.1.1.44 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PRK | 0.62 | 39.0 | 4.84e-01 | 93.2% | 99.5% |
| 3277496 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 42.0 | 4.46e-01 | 93.2% | 87.6% |
| 3959007 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 39.0 | 4.53e-01 | 92.6% | 99.6% |
| 4956528 | 2004.1.1.94 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATP_bind_1 | 0.53 | 39.0 | 4.51e-01 | 93.2% | 99.6% |
| 3375691 | 2004.1.1.94 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATP_bind_1 | 0.53 | 39.0 | 4.21e-01 | 93.5% | 86.3% |
| 4676398 | 2004.1.1.94 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ATP_bind_1 | 0.52 | 39.0 | 4.40e-01 | 93.2% | 98.8% |
| 4339805 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.51 | 27.0 | 3.35e-01 | 73.5% | 77.6% |
| 4419476 | 4958.1.1.1 ↗ | a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 | 0.51 | 28.0 | 3.79e-01 | 85.5% | 100.0% |
| 3285858 | 2004.1.1.88 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › cobW | 0.50 | 36.0 | 4.09e-01 | 92.6% | 96.7% |