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thymidine_kinase
Euk-VirCricetid_gammaherpesvirus_2
thymidine_kinase__YP_004207857__Cricetid_gammaherpesvirus_2__1605972
Identity
- Accession:
- YP_004207857 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
65.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Cricetid_gammaherpesvirus_2
TaxID: 1605972
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 258-282_414-556
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.53 | 27.0 | 3.16e-01 | 88.1% | 68.1% |
| 1jhgA00 | 1.10.1270.10 | Mainly Alpha › Orthogonal Bundle › Trp Operon Repressor; Chain A › TrpR-like | 0.52 | 27.0 | 3.38e-01 | 88.7% | 81.2% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.51 | 27.0 | 3.02e-01 | 86.9% | 63.3% |
D2
medium
residues 283-413_557-577
Domain cluster:
rep: thymidine_kinase__YP_009230154__Leporid_alphaherpesvirus_4__481315__D1-149_256-295
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 29.5 | 6.40e-07 | 89.5% | 48.2% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1e2jA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.88 | 85.0 | 6.49e-01 | 100.0% | 91.8% |
| 1p72A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.87 | 84.0 | 6.33e-01 | 100.0% | 89.8% |
| 1osnC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.86 | 82.0 | 6.24e-01 | 100.0% | 91.7% |
| 1p5zB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.71 | 60.0 | 5.12e-01 | 88.2% | 79.0% |
| 1zm7B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.68 | 57.0 | 5.19e-01 | 88.2% | 82.3% |
| 2yk0A03 | 1.20.58.1930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 3.89e-01 | 83.6% | 80.2% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 9545 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.90 | 86.0 | 6.43e-01 | 100.0% | 90.1% |
| 9546 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.87 | 83.0 | 6.27e-01 | 100.0% | 91.7% |
| 1322887 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.87 | 83.0 | 6.38e-01 | 100.0% | 92.5% |
| 3753842 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.71 | 61.0 | 5.21e-01 | 88.2% | 72.4% |
| 4435067 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.71 | 60.0 | 4.94e-01 | 88.2% | 74.9% |
| 315491 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.68 | 57.0 | 5.18e-01 | 87.5% | 82.3% |
| 3188362 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.60 | 50.0 | 4.49e-01 | 88.8% | 88.0% |
| 3789439 | 603.1.1.222 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Rbsn | 0.59 | 45.0 | 4.25e-01 | 78.3% | 90.0% |
| 4942854 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.59 | 49.0 | 4.47e-01 | 87.5% | 75.0% |
| 4279626 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.59 | 49.0 | 4.48e-01 | 89.5% | 87.8% |
| 4213018 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.59 | 49.0 | 4.44e-01 | 89.5% | 87.1% |
| 3713984 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.53 | 40.0 | 4.14e-01 | 82.2% | 83.6% |