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thymidine_kinase
Euk-VirAnopheles_minimus_iridovirus
thymidine_kinase__YP_009021189__Anopheles_minimus_iridovirus__1465751
Identity
- Accession:
- YP_009021189 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
93.3
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Iridoviridae›
Chloriridovirus›
Chloriridovirus_anopheles1
TaxID: 1465751
Cluster
View cluster (116 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 25-187
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01712.26 best | dNK | 129.4 | 2.20e-37 | 98.8% | 80.8% |
| PF02223.24 | Thymidylate_kin | 34.2 | 3.00e-08 | 90.2% | 69.7% |
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1p5zB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.94 | 91.0 | 7.90e-01 | 100.0% | 87.8% |
| 1zm7B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.93 | 83.0 | 7.65e-01 | 92.0% | 84.3% |
| 2jaqA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.89 | 86.0 | 8.09e-01 | 100.0% | 86.2% |
| 1osnC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.82 | 78.0 | 6.14e-01 | 100.0% | 83.1% |
| 1gtvA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.79 | 75.0 | 6.85e-01 | 100.0% | 88.0% |
| 3lv8A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.78 | 73.0 | 6.73e-01 | 100.0% | 85.3% |
| 1e9fA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.76 | 70.0 | 6.50e-01 | 100.0% | 78.2% |
| 4cvnA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.70 | 53.0 | 5.14e-01 | 100.0% | 70.9% |
| 3kb2A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.70 | 57.0 | 5.64e-01 | 100.0% | 81.9% |
| 3v9pB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 63.0 | 5.84e-01 | 100.0% | 88.1% |
| 3kfvA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 46.0 | 4.94e-01 | 100.0% | 81.6% |
| 2bwjA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 58.0 | 5.44e-01 | 100.0% | 82.1% |
| 2zm5B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 54.0 | 4.79e-01 | 100.0% | 89.6% |
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 33.0 | 3.94e-01 | 71.8% | 83.2% |
| 3cm0A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 50.0 | 4.84e-01 | 100.0% | 87.0% |
| 1e6bA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 34.0 | 3.94e-01 | 90.2% | 90.1% |
| 2k3oA00 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.54 | 29.0 | 3.25e-01 | 84.0% | 64.3% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 33.0 | 3.73e-01 | 79.8% | 78.9% |
| 2iksB02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 29.0 | 2.85e-01 | 86.5% | 46.0% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.53 | 30.0 | 3.76e-01 | 92.0% | 89.2% |
| 2cz2A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 40.0 | 4.43e-01 | 82.2% | 100.0% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.53 | 33.0 | 3.64e-01 | 92.0% | 78.6% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.52 | 34.0 | 3.71e-01 | 80.4% | 79.4% |
| 6uqyB01 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.51 | 46.0 | 3.89e-01 | 98.2% | 78.7% |
| 1f2eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 33.0 | 3.94e-01 | 87.7% | 100.0% |
| 3e74A02 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.51 | 45.0 | 3.67e-01 | 100.0% | 59.0% |
| 4iw9A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.50 | 34.0 | 3.90e-01 | 87.1% | 97.3% |
ECOD (59)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3314216 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.95 | 92.0 | 7.41e-01 | 100.0% | 81.4% |
| 3753842 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.95 | 92.0 | 8.03e-01 | 100.0% | 81.3% |
| 4435067 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.94 | 91.0 | 7.57e-01 | 100.0% | 83.9% |
| 3273940 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.93 | 90.0 | 8.09e-01 | 100.0% | 82.4% |
| 315491 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.93 | 83.0 | 7.64e-01 | 92.0% | 84.3% |
| 4032626 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.92 | 89.0 | 8.05e-01 | 100.0% | 84.8% |
| 3590072 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.92 | 89.0 | 7.66e-01 | 100.0% | 77.9% |
| 3256146 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.91 | 88.0 | 7.48e-01 | 100.0% | 71.0% |
| 4032154 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.90 | 87.0 | 8.00e-01 | 100.0% | 86.0% |
| 312817 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.90 | 87.0 | 8.13e-01 | 100.0% | 85.8% |
| 4418044 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.88 | 84.0 | 7.47e-01 | 100.0% | 82.6% |
| 5053129 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.87 | 83.0 | 7.51e-01 | 100.0% | 82.4% |
| 2056195 | 2004.1.1.70 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › dNK | 0.85 | 72.0 | 6.76e-01 | 88.3% | 88.8% |
| 4936538 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.83 | 79.0 | 6.88e-01 | 100.0% | 84.7% |
| 4942854 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.83 | 79.0 | 7.28e-01 | 100.0% | 83.5% |
| 4279626 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.83 | 79.0 | 7.22e-01 | 100.0% | 84.4% |
| 5064255 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.82 | 73.0 | 7.00e-01 | 100.0% | 83.9% |
| 5037208 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.82 | 78.0 | 6.91e-01 | 100.0% | 88.2% |
| 4193197 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.81 | 77.0 | 6.69e-01 | 100.0% | 80.0% |
| 5026353 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.81 | 76.0 | 7.16e-01 | 100.0% | 84.2% |
| 4307343 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.81 | 77.0 | 6.99e-01 | 100.0% | 84.8% |
| 4457642 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.81 | 77.0 | 6.92e-01 | 100.0% | 83.2% |
| 4133212 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.81 | 76.0 | 6.81e-01 | 100.0% | 81.4% |
| 4183580 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.81 | 74.0 | 6.88e-01 | 100.0% | 80.0% |
| 4573455 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.80 | 76.0 | 7.10e-01 | 100.0% | 87.7% |
| 5040462 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.80 | 76.0 | 6.88e-01 | 100.0% | 82.9% |
| 3702353 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.80 | 75.0 | 6.67e-01 | 100.0% | 85.8% |
| 4680943 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.80 | 76.0 | 7.02e-01 | 100.0% | 83.0% |
| 5069454 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.80 | 76.0 | 6.95e-01 | 100.0% | 84.8% |
| 3950209 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.79 | 75.0 | 6.83e-01 | 100.0% | 87.1% |
| 4636169 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.79 | 74.0 | 6.76e-01 | 100.0% | 85.2% |
| 4569464 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.79 | 74.0 | 6.93e-01 | 100.0% | 86.7% |
| 4957829 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.78 | 74.0 | 6.89e-01 | 100.0% | 84.0% |
| 4043560 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.78 | 74.0 | 6.89e-01 | 100.0% | 86.9% |
| 5033182 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.78 | 74.0 | 6.95e-01 | 100.0% | 86.1% |
| 4518593 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.78 | 74.0 | 6.78e-01 | 100.0% | 81.0% |
| None | — | 0.78 | 74.0 | 6.79e-01 | 100.0% | 81.9% | |
| 4587249 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.77 | 73.0 | 6.91e-01 | 100.0% | 86.8% |
| 4974163 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.77 | 73.0 | 6.57e-01 | 100.0% | 79.9% |
| 3591766 | 2004.1.1.79 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin | 0.74 | 69.0 | 5.75e-01 | 100.0% | 60.4% |
| 4972761 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.74 | 69.0 | 6.01e-01 | 100.0% | 84.5% |
| 4940619 | 2004.1.1.192 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 | 0.74 | 57.0 | 5.61e-01 | 100.0% | 74.9% |
| 4990030 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 67.0 | 5.94e-01 | 100.0% | 86.4% |
| 3891699 | 2004.1.1.41 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADK | 0.70 | 60.0 | 5.79e-01 | 100.0% | 80.0% |
| 3282741 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.70 | 58.0 | 5.76e-01 | 100.0% | 82.9% |
| 4254912 | 2004.1.1.60 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SKI | 0.68 | 58.0 | 5.74e-01 | 100.0% | 85.7% |
| None | — | 0.68 | 61.0 | 5.51e-01 | 100.0% | 72.6% | |
| 4312860 | 2004.1.1.60 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SKI | 0.67 | 57.0 | 5.52e-01 | 100.0% | 81.7% |
| 4014185 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.67 | 59.0 | 5.60e-01 | 100.0% | 81.1% |
| 3413676 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.65 | 61.0 | 5.46e-01 | 100.0% | 74.1% |
| None | — | 0.64 | 58.0 | 5.52e-01 | 100.0% | 84.1% | |
| 3592293 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.63 | 55.0 | 5.26e-01 | 100.0% | 80.0% |
| 3454879 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 36.0 | 4.16e-01 | 83.4% | 80.9% |
| 3588701 | 2004.1.1.50 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin | 0.61 | 55.0 | 5.38e-01 | 100.0% | 88.3% |
| 4406265 | 2004.1.1.71 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IPPT | 0.61 | 56.0 | 4.88e-01 | 100.0% | 89.6% |
| 3959007 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 50.0 | 4.40e-01 | 100.0% | 89.6% |
| 3630542 | 109.4.1.264 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RMD1-3 | 0.54 | 35.0 | 4.11e-01 | 84.7% | 95.5% |
| 4504299 | 109.2.1.16 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › LANC_like | 0.54 | 41.0 | 3.07e-01 | 79.1% | 89.8% |
| 5065759 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.52 | 38.0 | 4.25e-01 | 100.0% | 98.4% |