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thymidine_kinase
Euk-VirChrysochromulina_ericina_virus
thymidine_kinase__YP_009173315__Chrysochromulina_ericina_virus__455364
Identity
- Accession:
- YP_009173315 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
82.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Algavirales›
Phycodnaviridae›
Chrysochromulina_ericina_virus
TaxID: 455364
Cluster
View cluster (85 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-212
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00265.25 best | TK | 131.9 | 3.10e-38 | 86.3% | 98.9% |
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4tl8F00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.69 | 50.0 | 5.03e-01 | 74.1% | 76.5% |
| 3upuA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.68 | 48.0 | 5.27e-01 | 72.2% | 88.1% |
| 3e1sA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 48.0 | 4.85e-01 | 72.2% | 81.6% |
| 1s8nA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.65 | 35.0 | 4.28e-01 | 70.3% | 80.3% |
| 1r8jB01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.65 | 33.0 | 3.85e-01 | 70.3% | 67.1% |
| 2fwrA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 44.0 | 4.75e-01 | 72.6% | 84.3% |
| 3crmA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 36.0 | 4.24e-01 | 72.6% | 81.6% |
| 8jx6B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 49.0 | 5.06e-01 | 84.0% | 88.0% |
| 3flhB00 | 3.40.250.10 | Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain | 0.60 | 31.0 | 3.93e-01 | 82.1% | 82.6% |
| 4idhA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 52.0 | 5.28e-01 | 99.1% | 94.7% |
| 1wp9A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 47.0 | 4.85e-01 | 83.5% | 88.9% |
| 3nhvC01 | 3.40.250.10 | Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain | 0.58 | 31.0 | 3.90e-01 | 80.2% | 86.7% |
| 5l3qB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 43.0 | 4.15e-01 | 96.2% | 67.5% |
| 3f6cA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 35.0 | 4.41e-01 | 85.8% | 100.0% |
| 3graA00 | 3.40.50.880 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain | 0.57 | 37.0 | 4.00e-01 | 95.8% | 74.6% |
| 3i5xA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 48.0 | 4.48e-01 | 90.6% | 95.0% |
| 3mwyW03 | 3.40.50.10810 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain | 0.56 | 46.0 | 4.23e-01 | 85.4% | 90.3% |
| 1odfA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 41.0 | 3.70e-01 | 74.1% | 88.9% |
| 2vdwG00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.55 | 43.0 | 3.97e-01 | 80.7% | 92.0% |
| 1gcaA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 40.0 | 4.53e-01 | 92.0% | 98.1% |
| 5supC01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 44.0 | 4.47e-01 | 84.9% | 83.6% |
| 2yogA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 39.0 | 4.10e-01 | 96.2% | 78.7% |
| 3wrwA01 | 3.40.50.12020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Uncharacterised protein family UPF0261, NN domain | 0.55 | 38.0 | 4.07e-01 | 70.3% | 84.3% |
| 4omfG01 | 3.40.50.700 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NADH:ubiquinone oxidoreductase-like, 20kDa subunit | 0.54 | 32.0 | 3.57e-01 | 96.2% | 74.2% |
| 1ly1A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 38.0 | 4.38e-01 | 98.1% | 100.0% |
| 1dbrC00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 45.0 | 4.53e-01 | 90.6% | 96.3% |
| 4wd1A01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.51 | 40.0 | 3.22e-01 | 90.1% | 41.3% |
| 4d8lA00 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.50 | 38.0 | 3.38e-01 | 76.4% | 78.2% |
| 3lv8A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 40.0 | 4.07e-01 | 96.7% | 84.3% |
| 2qtlA03 | 3.40.50.80 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module | 0.50 | 36.0 | 4.10e-01 | 73.6% | 100.0% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4248117 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.95 | 62.0 | 7.74e-01 | 70.3% | 100.0% |
| 4081305 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.92 | 77.0 | 8.20e-01 | 90.1% | 95.3% |
| 3674153 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.91 | 83.0 | 8.19e-01 | 92.5% | 93.2% |
| 3717094 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.91 | 77.0 | 7.51e-01 | 90.6% | 81.3% |
| 4991383 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.88 | 72.0 | 7.89e-01 | 89.6% | 100.0% |
| 4462630 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.87 | 78.0 | 8.03e-01 | 99.5% | 96.1% |
| 4007998 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.86 | 76.0 | 7.78e-01 | 90.6% | 94.6% |
| 3976549 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.86 | 76.0 | 7.76e-01 | 90.6% | 94.6% |
| 4165287 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.84 | 73.0 | 7.53e-01 | 89.2% | 98.5% |
| 4628796 | 2004.1.1.28 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TK | 0.81 | 59.0 | 6.89e-01 | 73.6% | 100.0% |
| 3838853 | 2004.1.1.125 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › RuvB_N | 0.74 | 41.0 | 4.95e-01 | 72.2% | 79.3% |
| 4279180 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.72 | 42.0 | 4.86e-01 | 73.1% | 76.9% |
| 3196949 | 2004.1.1.366 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N | 0.69 | 47.0 | 5.01e-01 | 73.1% | 76.8% |
| 4030391 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.67 | 49.0 | 4.45e-01 | 73.1% | 84.4% |
| 3947000 | 2004.1.1.120 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII | 0.67 | 47.0 | 5.48e-01 | 73.6% | 99.3% |
| 3741693 | 2004.1.1.455 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase, UvrD_C, UvrD_C_2 | 0.67 | 59.0 | 4.01e-01 | 93.4% | 89.9% |
| 2512657 | 2004.1.1.62 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Viral_helicase1 | 0.67 | 47.0 | 5.32e-01 | 94.8% | 94.3% |
| 4006300 | 2004.1.1.455 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase, UvrD_C, UvrD_C_2 | 0.66 | 57.0 | 3.97e-01 | 90.6% | 93.0% |
| 4973762 | 2004.1.1.99 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Terminase_6N | 0.66 | 53.0 | 5.12e-01 | 83.5% | 85.8% |
| 4962524 | 2004.1.1.49 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase | 0.65 | 60.0 | 4.28e-01 | 99.5% | 96.6% |
| 1867152 | 2007.1.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg | 0.63 | 33.0 | 4.25e-01 | 80.7% | 87.3% |
| 3251898 | 7590.1.1.0 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs | 0.62 | 34.0 | 4.49e-01 | 85.8% | 95.7% |
| 419052 | 2004.1.1.232 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEXQc_Suv3 | 0.61 | 44.0 | 4.84e-01 | 84.4% | 89.0% |
| 3955799 | 2004.1.1.364 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C | 0.61 | 56.0 | 4.16e-01 | 98.6% | 76.6% |
| 5051560 | 2004.1.1.187 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DNA_pol3_delta2 | 0.61 | 43.0 | 4.67e-01 | 72.6% | 82.7% |
| 5041616 | 213.1.1.120 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › NAT10_TcmA_helicase | 0.61 | 57.0 | 3.93e-01 | 99.5% | 38.2% |
| 4972934 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.60 | 52.0 | 5.19e-01 | 94.3% | 87.9% |
| 3735958 | 2004.1.1.366 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N | 0.60 | 46.0 | 2.98e-01 | 77.8% | 21.6% |
| 4970114 | 2004.1.1.343 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_14 | 0.60 | 56.0 | 4.46e-01 | 99.1% | 68.8% |
| 3163821 | 2004.1.1.193 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_19 | 0.60 | 49.0 | 4.59e-01 | 84.0% | 93.3% |
| 5062874 | 2004.1.1.343 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_14 | 0.60 | 48.0 | 4.86e-01 | 84.0% | 82.8% |
| 4973417 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.59 | 43.0 | 4.33e-01 | 84.0% | 71.8% |
| 4382856 | 2004.1.1.211 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CLP1_P | 0.59 | 45.0 | 4.29e-01 | 96.2% | 67.9% |
| 1187396 | 2004.1.1.117 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Terminase_3 | 0.59 | 53.0 | 5.17e-01 | 100.0% | 87.1% |
| 3164763 | 2004.1.1.99 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Terminase_6N | 0.59 | 52.0 | 4.95e-01 | 94.8% | 86.4% |
| 4984756 | 2004.1.1.343 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_14 | 0.59 | 47.0 | 4.51e-01 | 83.5% | 84.9% |
| 1289553 | 2007.6.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS | 0.58 | 39.0 | 4.14e-01 | 79.7% | 76.9% |
| 3878864 | 2004.1.1.180 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_6 | 0.58 | 42.0 | 4.18e-01 | 72.6% | 73.0% |
| 4937848 | 2004.1.1.343 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_14 | 0.58 | 49.0 | 4.95e-01 | 88.7% | 90.7% |
| 3732225 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 54.0 | 3.99e-01 | 97.6% | 67.3% |
| 3692736 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 53.0 | 4.04e-01 | 97.6% | 70.9% |
| 3954923 | 2004.1.1.343 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_14 | 0.57 | 45.0 | 4.65e-01 | 80.7% | 93.5% |
| 4369666 | 2004.1.1.43 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 | 0.57 | 44.0 | 4.51e-01 | 96.7% | 81.9% |
| 3340067 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 46.0 | 4.07e-01 | 84.0% | 84.6% |
| 3729346 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.57 | 48.0 | 4.40e-01 | 91.5% | 96.5% |
| 3634704 | 2004.1.1.176 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Beta-Casp | 0.56 | 41.0 | 3.84e-01 | 96.7% | 59.3% |
| 3679306 | 2004.1.1.474 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynamin_N, MMR_HSR1 | 0.55 | 39.0 | 3.04e-01 | 73.1% | 52.1% |
| None | — | 0.55 | 49.0 | 4.78e-01 | 94.3% | 87.8% | |
| 4032496 | 2004.1.1.205 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_30 | 0.55 | 49.0 | 4.65e-01 | 94.3% | 84.9% |
| 3589264 | 2004.1.1.193 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_19 | 0.54 | 49.0 | 4.49e-01 | 94.3% | 77.0% |
| 3636544 | 2004.1.1.189 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_16 | 0.53 | 46.0 | 4.05e-01 | 89.6% | 93.6% |
| 3348287 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.50 | 35.0 | 3.64e-01 | 95.3% | 75.0% |