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thymidine_kinase
Euk-VirMacropodid_alphaherpesvirus_1
thymidine_kinase__YP_009227256__Macropodid_alphaherpesvirus_1__137443
Identity
- Accession:
- YP_009227256 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
89.7
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Macropodid_alphaherpesvirus_1
TaxID: 137443
Cluster
View cluster (35 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 33-53_66-86_142-178_193-326
Domain cluster:
rep: thymidina_kinase__YP_009664657__Bubaline_alphaherpesvirus_1__202910__D121-329
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 124.6 | 6.40e-36 | 73.7% | 61.8% |
D2
medium
residues 54-65_87-141_179-192_327-353
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 26.8 | 4.20e-06 | 61.1% | 17.1% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3e9lA02 | 1.20.80.40 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region | 0.65 | 38.0 | 4.10e-01 | 99.1% | 66.3% |
| 2cteA01 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.55 | 35.0 | 3.97e-01 | 96.3% | 87.3% |
| 3cjnA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 39.0 | 3.51e-01 | 74.1% | 97.3% |
| 3mk7C01 | 6.10.280.130 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 32.0 | 3.46e-01 | 83.3% | 68.1% |
| 3fryA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 27.0 | 3.32e-01 | 88.0% | 78.1% |
| 4r24B00 | 1.10.1660.10 | Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › | 0.53 | 28.0 | 3.16e-01 | 100.0% | 64.7% |
| 2qndA02 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.51 | 35.0 | 3.97e-01 | 95.4% | 95.0% |
| 3broD00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 36.0 | 3.35e-01 | 72.2% | 90.3% |
| 3spcA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.50 | 37.0 | 3.59e-01 | 78.7% | 70.9% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4588083 | 327.16.1.15 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › Secretin_N_2 | 0.65 | 39.0 | 4.82e-01 | 96.3% | 98.5% |
| 3387161 | 327.16.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system | 0.58 | 38.0 | 4.52e-01 | 95.4% | 97.3% |
| 3522222 | 5001.1.1.43 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › V1R | 0.56 | 46.0 | 3.72e-01 | 88.9% | 79.8% |
| 3829362 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.55 | 38.0 | 2.74e-01 | 72.2% | 79.1% |
| 167429 | 101.1.2.15 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR | 0.54 | 39.0 | 3.51e-01 | 74.1% | 97.3% |
| 3924002 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.53 | 33.0 | 3.99e-01 | 95.4% | 97.1% |
| 4132207 | 101.1.2.15 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR | 0.53 | 40.0 | 3.68e-01 | 80.6% | 90.3% |
| 3815375 | 5069.1.3.17 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF679 | 0.52 | 34.0 | 3.15e-01 | 83.3% | 50.7% |