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thymidine_kinase

Euk-Vir

Macropodid_alphaherpesvirus_1

thymidine_kinase__YP_009227256__Macropodid_alphaherpesvirus_1__137443

Identity

Accession:
YP_009227256 ↗
Protein ID:
thymidine_kinase
Kingdom:
euk

Quality

89.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 33-53_66-86_142-178_193-326
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00693.25 best Herpes_TK 124.6 6.40e-36 73.7% 61.8%
D2 medium residues 54-65_87-141_179-192_327-353
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00693.25 best Herpes_TK 26.8 4.20e-06 61.1% 17.1%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3e9lA02 1.20.80.40 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region 0.65 38.0 4.10e-01 99.1% 66.3%
2cteA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.55 35.0 3.97e-01 96.3% 87.3%
3cjnA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 39.0 3.51e-01 74.1% 97.3%
3mk7C01 6.10.280.130 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 32.0 3.46e-01 83.3% 68.1%
3fryA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 27.0 3.32e-01 88.0% 78.1%
4r24B00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.53 28.0 3.16e-01 100.0% 64.7%
2qndA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.51 35.0 3.97e-01 95.4% 95.0%
3broD00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 36.0 3.35e-01 72.2% 90.3%
3spcA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.50 37.0 3.59e-01 78.7% 70.9%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4588083 327.16.1.15 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › Secretin_N_2 0.65 39.0 4.82e-01 96.3% 98.5%
3387161 327.16.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system 0.58 38.0 4.52e-01 95.4% 97.3%
3522222 5001.1.1.43 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › V1R 0.56 46.0 3.72e-01 88.9% 79.8%
3829362 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.55 38.0 2.74e-01 72.2% 79.1%
167429 101.1.2.15 alpha arrays › HTH › HTH › winged helix domain › MarR 0.54 39.0 3.51e-01 74.1% 97.3%
3924002 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.53 33.0 3.99e-01 95.4% 97.1%
4132207 101.1.2.15 alpha arrays › HTH › HTH › winged helix domain › MarR 0.53 40.0 3.68e-01 80.6% 90.3%
3815375 5069.1.3.17 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF679 0.52 34.0 3.15e-01 83.3% 50.7%