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thymidine_kinase
Euk-VirWood_mouse_herpesvirus
thymidine_kinase__YP_010085896__Wood_mouse_herpesvirus__432370
Identity
- Accession:
- YP_010085896 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
60.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Wood_mouse_herpesvirus
TaxID: 432370
Cluster
View cluster (22 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 327-523_596-642
Domain cluster:
rep: thymidine_kinase__YP_009230154__Leporid_alphaherpesvirus_4__481315__D1-149_256-295
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01712.26 best | dNK | 40.2 | 4.60e-10 | 78.3% | 77.8% |
| PF00693.25 | Herpes_TK | 69.6 | 3.80e-19 | 77.0% | 67.1% |
| PF08465.16 | Herpes_TK_C | 43.7 | 2.50e-11 | 13.5% | 93.9% |
D2
medium
residues 524-595
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qvwA04 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.58 | 42.0 | 3.39e-01 | 77.8% | 61.4% |
| 2b3wA00 | 1.10.357.40 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › YbiA-like | 0.55 | 43.0 | 3.30e-01 | 100.0% | 36.3% |
| 1p4wA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 41.0 | 3.89e-01 | 84.7% | 67.8% |
| 3hhcC00 | 1.20.1250.60 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda | 0.54 | 41.0 | 3.27e-01 | 81.9% | 74.2% |
| 2j0wA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.54 | 46.0 | 4.34e-01 | 100.0% | 88.2% |
| 3gruA02 | 1.10.8.100 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › rRNA adenine dimethylase, C-terminal domain | 0.54 | 45.0 | 4.36e-01 | 98.6% | 86.0% |
| 2q0yA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.52 | 40.0 | 3.26e-01 | 83.3% | 47.1% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3929697 | 101.1.1.3 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding | 0.65 | 45.0 | 4.06e-01 | 73.6% | 51.4% |
| 3812411 | 101.1.1.69 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_7 | 0.65 | 46.0 | 4.26e-01 | 76.4% | 63.2% |
| 3289678 | 101.1.1.58 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 | 0.64 | 46.0 | 4.90e-01 | 76.4% | 98.3% |
| 3395545 | 101.1.1.69 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_7 | 0.63 | 45.0 | 4.08e-01 | 76.4% | 56.0% |
| 4961280 | 101.1.2.939 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF26270 | 0.60 | 48.0 | 4.95e-01 | 100.0% | 98.5% |
| 4458965 | 101.1.1.63 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_28 | 0.60 | 41.0 | 4.03e-01 | 72.2% | 82.5% |
| 3687110 | 101.1.1.36 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeobox_KN | 0.60 | 42.0 | 4.08e-01 | 73.6% | 75.0% |
| 3964894 | 101.1.1.58 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_18 | 0.60 | 42.0 | 3.83e-01 | 75.0% | 73.0% |
| 4936844 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.59 | 46.0 | 4.60e-01 | 88.9% | 94.7% |
| 3960027 | 101.1.1.535 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › LCM | 0.57 | 41.0 | 3.98e-01 | 76.4% | 93.8% |
| 4241531 | 101.1.3.1 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE | 0.56 | 41.0 | 4.22e-01 | 88.9% | 84.3% |
| 4057034 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.53 | 41.0 | 4.06e-01 | 86.1% | 81.3% |
| 3938616 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.51 | 41.0 | 3.88e-01 | 94.4% | 74.7% |