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thymidine_kinase
Euk-VirGallid_alphaherpesvirus_1
thymidine_kinase__YP_182352__Gallid_alphaherpesvirus_1__10386
Identity
- Accession:
- YP_182352 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
81.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Iltovirus›
Gallid_alphaherpesvirus_1
TaxID: 10386
Cluster
View cluster (35 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 12-153_187-201_340-364
Domain cluster:
rep: thymidine_kinase__YP_009230154__Leporid_alphaherpesvirus_4__481315__D1-149_256-295
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 95.2 | 6.20e-27 | 67.6% | 42.1% |
D2
medium
residues 154-186_202-339
Domain cluster:
rep: thymidina_kinase__YP_009664657__Bubaline_alphaherpesvirus_1__202910__D121-329
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 59.1 | 6.20e-16 | 71.4% | 40.7% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1p72A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.85 | 82.0 | 6.42e-01 | 100.0% | 56.7% |
| 1osnC00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.84 | 81.0 | 6.39e-01 | 100.0% | 56.2% |
| 1e2jA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.82 | 77.0 | 6.08e-01 | 100.0% | 53.9% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 26.0 | 3.21e-01 | 84.8% | 71.3% |
| 1ax8A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 26.0 | 2.86e-01 | 88.9% | 58.5% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 9545 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.85 | 82.0 | 6.36e-01 | 100.0% | 55.0% |
| 9546 | 2004.1.1.52 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_TK | 0.84 | 81.0 | 6.31e-01 | 100.0% | 54.2% |
| 2157267 | 109.4.1.204 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_EZ | 0.55 | 31.0 | 3.69e-01 | 83.6% | 79.3% |
| 4971759 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.53 | 30.0 | 3.31e-01 | 91.2% | 67.1% |