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thymidine_kinase
Euk-VirHuman_gammaherpesvirus_4
thymidine_kinase__YP_401701__Human_gammaherpesvirus_4__10376
Identity
- Accession:
- YP_401701 ↗
- Protein ID:
- thymidine_kinase
- Kingdom:
- euk
Quality
61.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Lymphocryptovirus›
human_gammaherpesvirus_4
TaxID: 10376
Cluster
View cluster (22 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 281-304_447-563
D2
medium
residues 305-392_564-607
Domain cluster:
rep: thymidine_kinase__YP_009118411__Equid_gammaherpesvirus_5__10371__D300-425_605-623
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00693.25 best | Herpes_TK | 27.1 | 3.40e-06 | 69.7% | 26.1% |
| PF08465.16 | Herpes_TK_C | 69.2 | 2.70e-19 | 23.5% | 93.9% |
D3
medium
residues 393-446
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3qxzA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.64 | 45.0 | 4.36e-01 | 74.1% | 95.0% |
| 3zdmB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.63 | 44.0 | 4.55e-01 | 74.1% | 98.0% |
| 4jvyB00 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.61 | 44.0 | 3.10e-01 | 79.6% | 95.3% |
| 5o6uB00 | 3.30.70.2540 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › CRISPR-associated endoribonuclease Cas6/Csy4 | 0.59 | 44.0 | 3.16e-01 | 83.3% | 26.4% |
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.54 | 44.0 | 4.04e-01 | 100.0% | 81.0% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3695742 | 109.3.1.315 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF27826 | 0.79 | 58.0 | 3.72e-01 | 77.8% | 27.1% |
| 4033267 | 4317.1.1.1 ↗ | a+b duplicates or obligate multimers › YdfO-like › YdfO-like › YdfO-like › DUF1398 | 0.70 | 49.0 | 4.70e-01 | 72.2% | 90.0% |
| 2101211 | 304.51.1.5 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Csy4 | 0.59 | 44.0 | 3.81e-01 | 83.3% | 52.7% |